ITGB5 (integrin subunit beta 5)

Gene

• Entrez ID: 3693
• Gene name: Integrin subunit beta 5
• Gene symbol: ITGB5
• Synonyms (NCBI Gene): -
• Chromosome: 3
• Chromosome location: 3q21.2
• Summary: This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signal

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018321	hsa-miR-335-5p	Microarray	18185580
MIRT020894	hsa-miR-155-5p	Proteomics	18668040
MIRT051994	hsa-let-7b-5p	CLASH	23622248
MIRT1074167	hsa-miR-1179	CLIP-seq
MIRT1074168	hsa-miR-1207-5p	CLIP-seq
MIRT1074169	hsa-miR-1287	CLIP-seq
MIRT1074170	hsa-miR-1302	CLIP-seq
MIRT1074171	hsa-miR-1321	CLIP-seq
MIRT1074172	hsa-miR-1343	CLIP-seq
MIRT1074173	hsa-miR-185	CLIP-seq
MIRT1074174	hsa-miR-1973	CLIP-seq
MIRT1074175	hsa-miR-3122	CLIP-seq
MIRT1074176	hsa-miR-3136-3p	CLIP-seq
MIRT1074177	hsa-miR-3153	CLIP-seq
MIRT1074178	hsa-miR-3154	CLIP-seq
MIRT1074179	hsa-miR-3155	CLIP-seq
MIRT1074180	hsa-miR-3155b	CLIP-seq
MIRT1074181	hsa-miR-3162-5p	CLIP-seq
MIRT1074182	hsa-miR-3202	CLIP-seq
MIRT1074183	hsa-miR-320a	CLIP-seq
MIRT1074184	hsa-miR-320b	CLIP-seq
MIRT1074185	hsa-miR-320c	CLIP-seq
MIRT1074186	hsa-miR-320d	CLIP-seq
MIRT1074187	hsa-miR-320e	CLIP-seq
MIRT1074188	hsa-miR-338-3p	CLIP-seq
MIRT1074189	hsa-miR-339-3p	CLIP-seq
MIRT1074190	hsa-miR-3682-5p	CLIP-seq
MIRT1074191	hsa-miR-3688-5p	CLIP-seq
MIRT1074192	hsa-miR-3690	CLIP-seq
MIRT1074193	hsa-miR-3913-5p	CLIP-seq
MIRT1074194	hsa-miR-4254	CLIP-seq
MIRT1074195	hsa-miR-4256	CLIP-seq
MIRT1074196	hsa-miR-4264	CLIP-seq
MIRT1074197	hsa-miR-4284	CLIP-seq
MIRT1074198	hsa-miR-4298	CLIP-seq
MIRT1074199	hsa-miR-4300	CLIP-seq
MIRT1074200	hsa-miR-4306	CLIP-seq
MIRT1074201	hsa-miR-4310	CLIP-seq
MIRT1074202	hsa-miR-4429	CLIP-seq
MIRT1074203	hsa-miR-4437	CLIP-seq
MIRT1074204	hsa-miR-4488	CLIP-seq
MIRT1074205	hsa-miR-4505	CLIP-seq
MIRT1074206	hsa-miR-4533	CLIP-seq
MIRT1074207	hsa-miR-4644	CLIP-seq
MIRT1074208	hsa-miR-4674	CLIP-seq
MIRT1074209	hsa-miR-4679	CLIP-seq
MIRT1074210	hsa-miR-4690-3p	CLIP-seq
MIRT1074211	hsa-miR-4697-5p	CLIP-seq
MIRT1074212	hsa-miR-4708-3p	CLIP-seq
MIRT1074213	hsa-miR-4731-5p	CLIP-seq
MIRT1074214	hsa-miR-4733-5p	CLIP-seq
MIRT1074215	hsa-miR-4736	CLIP-seq
MIRT1074216	hsa-miR-4739	CLIP-seq
MIRT1074217	hsa-miR-4756-5p	CLIP-seq
MIRT1074218	hsa-miR-4763-3p	CLIP-seq
MIRT1074219	hsa-miR-4764-5p	CLIP-seq
MIRT1074220	hsa-miR-4797-3p	CLIP-seq
MIRT1074221	hsa-miR-484	CLIP-seq
MIRT1074222	hsa-miR-493	CLIP-seq
MIRT1074223	hsa-miR-622	CLIP-seq
MIRT1074224	hsa-miR-637	CLIP-seq
MIRT1074225	hsa-miR-659	CLIP-seq
MIRT1074226	hsa-miR-920	CLIP-seq
MIRT1074227	hsa-miR-942	CLIP-seq
MIRT1074168	hsa-miR-1207-5p	CLIP-seq
MIRT1074169	hsa-miR-1287	CLIP-seq
MIRT1074170	hsa-miR-1302	CLIP-seq
MIRT1074173	hsa-miR-185	CLIP-seq
MIRT1074175	hsa-miR-3122	CLIP-seq
MIRT2018327	hsa-miR-3127-3p	CLIP-seq
MIRT2018328	hsa-miR-3189-5p	CLIP-seq
MIRT1074182	hsa-miR-3202	CLIP-seq
MIRT1074183	hsa-miR-320a	CLIP-seq
MIRT1074184	hsa-miR-320b	CLIP-seq
MIRT1074185	hsa-miR-320c	CLIP-seq
MIRT1074186	hsa-miR-320d	CLIP-seq
MIRT1074187	hsa-miR-320e	CLIP-seq
MIRT1074188	hsa-miR-338-3p	CLIP-seq
MIRT1074189	hsa-miR-339-3p	CLIP-seq
MIRT1074191	hsa-miR-3688-5p	CLIP-seq
MIRT1074193	hsa-miR-3913-5p	CLIP-seq
MIRT2018329	hsa-miR-421	CLIP-seq
MIRT1074196	hsa-miR-4264	CLIP-seq
MIRT1074198	hsa-miR-4298	CLIP-seq
MIRT1074200	hsa-miR-4306	CLIP-seq
MIRT2018330	hsa-miR-4323	CLIP-seq
MIRT1074202	hsa-miR-4429	CLIP-seq
MIRT2018331	hsa-miR-450b-5p	CLIP-seq
MIRT1074207	hsa-miR-4644	CLIP-seq
MIRT1074210	hsa-miR-4690-3p	CLIP-seq
MIRT2018332	hsa-miR-4709-5p	CLIP-seq
MIRT1074214	hsa-miR-4733-5p	CLIP-seq
MIRT1074215	hsa-miR-4736	CLIP-seq
MIRT1074218	hsa-miR-4763-3p	CLIP-seq
MIRT1074219	hsa-miR-4764-5p	CLIP-seq
MIRT1074220	hsa-miR-4797-3p	CLIP-seq
MIRT2018333	hsa-miR-518a-5p	CLIP-seq
MIRT2018334	hsa-miR-527	CLIP-seq
MIRT2250200	hsa-miR-103b	CLIP-seq
MIRT1074167	hsa-miR-1179	CLIP-seq
MIRT2250201	hsa-miR-1266	CLIP-seq
MIRT1074169	hsa-miR-1287	CLIP-seq
MIRT1074172	hsa-miR-1343	CLIP-seq
MIRT1074173	hsa-miR-185	CLIP-seq
MIRT2250202	hsa-miR-3163	CLIP-seq
MIRT1074182	hsa-miR-3202	CLIP-seq
MIRT1074187	hsa-miR-320e	CLIP-seq
MIRT1074188	hsa-miR-338-3p	CLIP-seq
MIRT2250203	hsa-miR-340	CLIP-seq
MIRT2250204	hsa-miR-3664-3p	CLIP-seq
MIRT1074192	hsa-miR-3690	CLIP-seq
MIRT2018329	hsa-miR-421	CLIP-seq
MIRT1074194	hsa-miR-4254	CLIP-seq
MIRT1074196	hsa-miR-4264	CLIP-seq
MIRT1074200	hsa-miR-4306	CLIP-seq
MIRT1074201	hsa-miR-4310	CLIP-seq
MIRT2250205	hsa-miR-4436a	CLIP-seq
MIRT2018331	hsa-miR-450b-5p	CLIP-seq
MIRT2250206	hsa-miR-4518	CLIP-seq
MIRT2250207	hsa-miR-4528	CLIP-seq
MIRT1074206	hsa-miR-4533	CLIP-seq
MIRT1074207	hsa-miR-4644	CLIP-seq
MIRT1074210	hsa-miR-4690-3p	CLIP-seq
MIRT2018332	hsa-miR-4709-5p	CLIP-seq
MIRT2250208	hsa-miR-4719	CLIP-seq
MIRT2250209	hsa-miR-4724-3p	CLIP-seq
MIRT1074220	hsa-miR-4797-3p	CLIP-seq
MIRT2018333	hsa-miR-518a-5p	CLIP-seq
MIRT2018334	hsa-miR-527	CLIP-seq
MIRT2250210	hsa-miR-548n	CLIP-seq
MIRT2250211	hsa-miR-548t	CLIP-seq
MIRT2452007	hsa-miR-3176	CLIP-seq
MIRT2452008	hsa-miR-3622b-5p	CLIP-seq
MIRT2452009	hsa-miR-3922-3p	CLIP-seq
MIRT2452010	hsa-miR-4720-5p	CLIP-seq
MIRT2452011	hsa-miR-4799-3p	CLIP-seq
MIRT2452012	hsa-miR-760	CLIP-seq
MIRT2250200	hsa-miR-103b	CLIP-seq
MIRT1074167	hsa-miR-1179	CLIP-seq
MIRT1074168	hsa-miR-1207-5p	CLIP-seq
MIRT2553731	hsa-miR-1231	CLIP-seq
MIRT2553732	hsa-miR-125a-3p	CLIP-seq
MIRT2250201	hsa-miR-1266	CLIP-seq
MIRT2553733	hsa-miR-1286	CLIP-seq
MIRT1074169	hsa-miR-1287	CLIP-seq
MIRT1074170	hsa-miR-1302	CLIP-seq
MIRT1074171	hsa-miR-1321	CLIP-seq
MIRT1074172	hsa-miR-1343	CLIP-seq
MIRT2553734	hsa-miR-15a	CLIP-seq
MIRT2553735	hsa-miR-15b	CLIP-seq
MIRT2553736	hsa-miR-16	CLIP-seq
MIRT1074173	hsa-miR-185	CLIP-seq
MIRT2553737	hsa-miR-195	CLIP-seq
MIRT1074174	hsa-miR-1973	CLIP-seq
MIRT2553738	hsa-miR-19a	CLIP-seq
MIRT2553739	hsa-miR-19b	CLIP-seq
MIRT1074175	hsa-miR-3122	CLIP-seq
MIRT2553740	hsa-miR-3126-5p	CLIP-seq
MIRT2018327	hsa-miR-3127-3p	CLIP-seq
MIRT1074176	hsa-miR-3136-3p	CLIP-seq
MIRT1074177	hsa-miR-3153	CLIP-seq
MIRT1074178	hsa-miR-3154	CLIP-seq
MIRT1074179	hsa-miR-3155	CLIP-seq
MIRT1074180	hsa-miR-3155b	CLIP-seq
MIRT1074181	hsa-miR-3162-5p	CLIP-seq
MIRT2452007	hsa-miR-3176	CLIP-seq
MIRT2018328	hsa-miR-3189-5p	CLIP-seq
MIRT1074182	hsa-miR-3202	CLIP-seq
MIRT1074183	hsa-miR-320a	CLIP-seq
MIRT1074184	hsa-miR-320b	CLIP-seq
MIRT1074185	hsa-miR-320c	CLIP-seq
MIRT1074186	hsa-miR-320d	CLIP-seq
MIRT1074187	hsa-miR-320e	CLIP-seq
MIRT1074188	hsa-miR-338-3p	CLIP-seq
MIRT1074189	hsa-miR-339-3p	CLIP-seq
MIRT2452008	hsa-miR-3622b-5p	CLIP-seq
MIRT2553741	hsa-miR-3655	CLIP-seq
MIRT2250204	hsa-miR-3664-3p	CLIP-seq
MIRT1074190	hsa-miR-3682-5p	CLIP-seq
MIRT1074191	hsa-miR-3688-5p	CLIP-seq
MIRT1074192	hsa-miR-3690	CLIP-seq
MIRT2553742	hsa-miR-3910	CLIP-seq
MIRT1074193	hsa-miR-3913-5p	CLIP-seq
MIRT2452009	hsa-miR-3922-3p	CLIP-seq
MIRT2018329	hsa-miR-421	CLIP-seq
MIRT2553743	hsa-miR-424	CLIP-seq
MIRT1074194	hsa-miR-4254	CLIP-seq
MIRT1074195	hsa-miR-4256	CLIP-seq
MIRT1074196	hsa-miR-4264	CLIP-seq
MIRT2553744	hsa-miR-4265	CLIP-seq
MIRT1074197	hsa-miR-4284	CLIP-seq
MIRT2553745	hsa-miR-4288	CLIP-seq
MIRT2553746	hsa-miR-4296	CLIP-seq
MIRT1074198	hsa-miR-4298	CLIP-seq
MIRT1074199	hsa-miR-4300	CLIP-seq
MIRT1074200	hsa-miR-4306	CLIP-seq
MIRT1074201	hsa-miR-4310	CLIP-seq
MIRT2553747	hsa-miR-4318	CLIP-seq
MIRT2553748	hsa-miR-4322	CLIP-seq
MIRT2018330	hsa-miR-4323	CLIP-seq
MIRT2553749	hsa-miR-4417	CLIP-seq
MIRT1074202	hsa-miR-4429	CLIP-seq
MIRT2553750	hsa-miR-4435	CLIP-seq
MIRT2250205	hsa-miR-4436a	CLIP-seq
MIRT1074203	hsa-miR-4437	CLIP-seq
MIRT1074204	hsa-miR-4488	CLIP-seq
MIRT1074205	hsa-miR-4505	CLIP-seq
MIRT2018331	hsa-miR-450b-5p	CLIP-seq
MIRT2250206	hsa-miR-4518	CLIP-seq
MIRT2553751	hsa-miR-4524	CLIP-seq
MIRT1074206	hsa-miR-4533	CLIP-seq
MIRT1074207	hsa-miR-4644	CLIP-seq
MIRT2553752	hsa-miR-4645-3p	CLIP-seq
MIRT1074208	hsa-miR-4674	CLIP-seq
MIRT1074209	hsa-miR-4679	CLIP-seq
MIRT1074210	hsa-miR-4690-3p	CLIP-seq
MIRT1074211	hsa-miR-4697-5p	CLIP-seq
MIRT1074212	hsa-miR-4708-3p	CLIP-seq
MIRT2018332	hsa-miR-4709-5p	CLIP-seq
MIRT2250208	hsa-miR-4719	CLIP-seq
MIRT2452010	hsa-miR-4720-5p	CLIP-seq
MIRT2553753	hsa-miR-4722-5p	CLIP-seq
MIRT2250209	hsa-miR-4724-3p	CLIP-seq
MIRT1074213	hsa-miR-4731-5p	CLIP-seq
MIRT1074214	hsa-miR-4733-5p	CLIP-seq
MIRT1074215	hsa-miR-4736	CLIP-seq
MIRT1074216	hsa-miR-4739	CLIP-seq
MIRT2553754	hsa-miR-4755-3p	CLIP-seq
MIRT1074217	hsa-miR-4756-5p	CLIP-seq
MIRT1074218	hsa-miR-4763-3p	CLIP-seq
MIRT1074219	hsa-miR-4764-5p	CLIP-seq
MIRT2553755	hsa-miR-4778-3p	CLIP-seq
MIRT1074220	hsa-miR-4797-3p	CLIP-seq
MIRT2452011	hsa-miR-4799-3p	CLIP-seq
MIRT1074221	hsa-miR-484	CLIP-seq
MIRT1074222	hsa-miR-493	CLIP-seq
MIRT2553756	hsa-miR-497	CLIP-seq
MIRT2553757	hsa-miR-503	CLIP-seq
MIRT2018333	hsa-miR-518a-5p	CLIP-seq
MIRT2018334	hsa-miR-527	CLIP-seq
MIRT2553758	hsa-miR-578	CLIP-seq
MIRT1074223	hsa-miR-622	CLIP-seq
MIRT2553759	hsa-miR-632	CLIP-seq
MIRT1074224	hsa-miR-637	CLIP-seq
MIRT2553760	hsa-miR-646	CLIP-seq
MIRT1074225	hsa-miR-659	CLIP-seq
MIRT2452012	hsa-miR-760	CLIP-seq
MIRT1074226	hsa-miR-920	CLIP-seq
MIRT1074227	hsa-miR-942	CLIP-seq
MIRT2250200	hsa-miR-103b	CLIP-seq
MIRT1074167	hsa-miR-1179	CLIP-seq
MIRT1074168	hsa-miR-1207-5p	CLIP-seq
MIRT2553731	hsa-miR-1231	CLIP-seq
MIRT2250201	hsa-miR-1266	CLIP-seq
MIRT2553733	hsa-miR-1286	CLIP-seq
MIRT1074169	hsa-miR-1287	CLIP-seq
MIRT1074170	hsa-miR-1302	CLIP-seq
MIRT1074171	hsa-miR-1321	CLIP-seq
MIRT1074172	hsa-miR-1343	CLIP-seq
MIRT2553734	hsa-miR-15a	CLIP-seq
MIRT2553735	hsa-miR-15b	CLIP-seq
MIRT2553736	hsa-miR-16	CLIP-seq
MIRT2553737	hsa-miR-195	CLIP-seq
MIRT1074174	hsa-miR-1973	CLIP-seq
MIRT2553738	hsa-miR-19a	CLIP-seq
MIRT2553739	hsa-miR-19b	CLIP-seq
MIRT1074175	hsa-miR-3122	CLIP-seq
MIRT2553740	hsa-miR-3126-5p	CLIP-seq
MIRT2018327	hsa-miR-3127-3p	CLIP-seq
MIRT1074176	hsa-miR-3136-3p	CLIP-seq
MIRT1074177	hsa-miR-3153	CLIP-seq
MIRT1074178	hsa-miR-3154	CLIP-seq
MIRT1074179	hsa-miR-3155	CLIP-seq
MIRT1074180	hsa-miR-3155b	CLIP-seq
MIRT1074181	hsa-miR-3162-5p	CLIP-seq
MIRT2452007	hsa-miR-3176	CLIP-seq
MIRT2018328	hsa-miR-3189-5p	CLIP-seq
MIRT1074182	hsa-miR-3202	CLIP-seq
MIRT1074183	hsa-miR-320a	CLIP-seq
MIRT1074184	hsa-miR-320b	CLIP-seq
MIRT1074185	hsa-miR-320c	CLIP-seq
MIRT1074186	hsa-miR-320d	CLIP-seq
MIRT1074187	hsa-miR-320e	CLIP-seq
MIRT1074188	hsa-miR-338-3p	CLIP-seq
MIRT1074189	hsa-miR-339-3p	CLIP-seq
MIRT2452008	hsa-miR-3622b-5p	CLIP-seq
MIRT2553741	hsa-miR-3655	CLIP-seq
MIRT2250204	hsa-miR-3664-3p	CLIP-seq
MIRT1074191	hsa-miR-3688-5p	CLIP-seq
MIRT1074192	hsa-miR-3690	CLIP-seq
MIRT2553742	hsa-miR-3910	CLIP-seq
MIRT1074193	hsa-miR-3913-5p	CLIP-seq
MIRT2452009	hsa-miR-3922-3p	CLIP-seq
MIRT2018329	hsa-miR-421	CLIP-seq
MIRT2553743	hsa-miR-424	CLIP-seq
MIRT1074194	hsa-miR-4254	CLIP-seq
MIRT1074195	hsa-miR-4256	CLIP-seq
MIRT1074196	hsa-miR-4264	CLIP-seq
MIRT2553744	hsa-miR-4265	CLIP-seq
MIRT1074197	hsa-miR-4284	CLIP-seq
MIRT2553745	hsa-miR-4288	CLIP-seq
MIRT2553746	hsa-miR-4296	CLIP-seq
MIRT1074198	hsa-miR-4298	CLIP-seq
MIRT1074199	hsa-miR-4300	CLIP-seq
MIRT1074201	hsa-miR-4310	CLIP-seq
MIRT2553747	hsa-miR-4318	CLIP-seq
MIRT2553748	hsa-miR-4322	CLIP-seq
MIRT2018330	hsa-miR-4323	CLIP-seq
MIRT2553749	hsa-miR-4417	CLIP-seq
MIRT1074202	hsa-miR-4429	CLIP-seq
MIRT2553750	hsa-miR-4435	CLIP-seq
MIRT2250205	hsa-miR-4436a	CLIP-seq
MIRT1074203	hsa-miR-4437	CLIP-seq
MIRT1074204	hsa-miR-4488	CLIP-seq
MIRT1074205	hsa-miR-4505	CLIP-seq
MIRT2018331	hsa-miR-450b-5p	CLIP-seq
MIRT2250206	hsa-miR-4518	CLIP-seq
MIRT2553751	hsa-miR-4524	CLIP-seq
MIRT1074206	hsa-miR-4533	CLIP-seq
MIRT2553752	hsa-miR-4645-3p	CLIP-seq
MIRT1074208	hsa-miR-4674	CLIP-seq
MIRT1074209	hsa-miR-4679	CLIP-seq
MIRT1074210	hsa-miR-4690-3p	CLIP-seq
MIRT1074211	hsa-miR-4697-5p	CLIP-seq
MIRT1074212	hsa-miR-4708-3p	CLIP-seq
MIRT2018332	hsa-miR-4709-5p	CLIP-seq
MIRT2452010	hsa-miR-4720-5p	CLIP-seq
MIRT2553753	hsa-miR-4722-5p	CLIP-seq
MIRT2250209	hsa-miR-4724-3p	CLIP-seq
MIRT1074213	hsa-miR-4731-5p	CLIP-seq
MIRT1074214	hsa-miR-4733-5p	CLIP-seq
MIRT1074215	hsa-miR-4736	CLIP-seq
MIRT1074216	hsa-miR-4739	CLIP-seq
MIRT2553754	hsa-miR-4755-3p	CLIP-seq
MIRT1074217	hsa-miR-4756-5p	CLIP-seq
MIRT1074218	hsa-miR-4763-3p	CLIP-seq
MIRT1074219	hsa-miR-4764-5p	CLIP-seq
MIRT2553755	hsa-miR-4778-3p	CLIP-seq
MIRT1074220	hsa-miR-4797-3p	CLIP-seq
MIRT2452011	hsa-miR-4799-3p	CLIP-seq
MIRT1074221	hsa-miR-484	CLIP-seq
MIRT1074222	hsa-miR-493	CLIP-seq
MIRT2553756	hsa-miR-497	CLIP-seq
MIRT2553757	hsa-miR-503	CLIP-seq
MIRT2018333	hsa-miR-518a-5p	CLIP-seq
MIRT2018334	hsa-miR-527	CLIP-seq
MIRT2553758	hsa-miR-578	CLIP-seq
MIRT1074223	hsa-miR-622	CLIP-seq
MIRT2553759	hsa-miR-632	CLIP-seq
MIRT1074224	hsa-miR-637	CLIP-seq
MIRT2553760	hsa-miR-646	CLIP-seq
MIRT2452012	hsa-miR-760	CLIP-seq
MIRT1074226	hsa-miR-920	CLIP-seq
MIRT1074227	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001618	Function	Virus receptor activity	IEA
GO:0001704	Process	Formation of primary germ layer	IEA
GO:0005102	Function	Signaling receptor binding	IEA
GO:0005178	Function	Integrin binding	IBA
GO:0005515	Function	Protein binding	IPI	1694173, 15611078, 19910644, 21397862, 21642953, 24997346, 25448675, 32296183
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	IBA
GO:0007160	Process	Cell-matrix adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	IMP	24036928
GO:0007160	Process	Cell-matrix adhesion	NAS	19693543
GO:0007179	Process	Transforming growth factor beta receptor signaling pathway	IBA
GO:0007179	Process	Transforming growth factor beta receptor signaling pathway	IEA
GO:0007179	Process	Transforming growth factor beta receptor signaling pathway	IMP	24036928
GO:0007229	Process	Integrin-mediated signaling pathway	IBA
GO:0007229	Process	Integrin-mediated signaling pathway	IEA
GO:0007229	Process	Integrin-mediated signaling pathway	IMP	24036928
GO:0007229	Process	Integrin-mediated signaling pathway	NAS	19693543
GO:0008305	Component	Integrin complex	IBA
GO:0009986	Component	Cell surface	HDA	23658023
GO:0009986	Component	Cell surface	IBA
GO:0009986	Component	Cell surface	IDA	7525578, 23154389, 24036928, 25063885
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IBA
GO:0016477	Process	Cell migration	IMP	26934001
GO:0033627	Process	Cell adhesion mediated by integrin	IBA
GO:0034684	Component	Integrin alphav-beta5 complex	IDA	25063885
GO:0034684	Component	Integrin alphav-beta5 complex	IEA
GO:0034684	Component	Integrin alphav-beta5 complex	IPI	1694173
GO:0035313	Process	Wound healing, spreading of epidermal cells	NAS	19693543
GO:0035987	Process	Endodermal cell differentiation	IEP	23154389
GO:0043149	Process	Stress fiber assembly	IBA
GO:0043149	Process	Stress fiber assembly	IEA
GO:0043149	Process	Stress fiber assembly	IMP	24036928
GO:0043235	Component	Receptor complex	IDA	23382219
GO:0045335	Component	Phagocytic vesicle	TAS
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0090136	Process	Epithelial cell-cell adhesion	IMP	24036928
GO:0098609	Process	Cell-cell adhesion	IBA

Other IDs

• MIM: 147561
• HGNC: 6160
• e!Ensembl: ENSG00000082781

Protein

• UniProt ID: P18084
• Protein name: Integrin beta-5
• Protein function: Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.; (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C.
• PDB: 7S46, 7S47, 7S48
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF17205	PSI_integrin	26 → 76	Integrin plexin domain	Domain
  PF00362	Integrin_beta	133 → 382	Integrin beta chain VWA domain	Domain
  PF18372	I-EGF_1	465 → 493	Integrin beta epidermal growth factor like domain 1	Domain
  PF07965	Integrin_B_tail	635 → 719	Integrin beta tail domain	Domain
  PF08725	Integrin_b_cyt	743 → 788	Integrin beta cytoplasmic domain	Domain

• Sequence:

  MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
  TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
  GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
  SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
  RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
  HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
  DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
  TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
  TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
  GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
  ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
  CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
  MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
  HTVDFTFNKFNKSYNGTVD

• Sequence length: 799

Pathways

KEGG:

Phagosome
Efferocytosis
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Regulation of actin cytoskeleton
Cytoskeleton in muscle cells
Human papillomavirus infection
Proteoglycans in cancer
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy

Reactome:

Cross-presentation of particulate exogenous antigens (phagosomes)
Molecules associated with elastic fibres
Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
Smooth Muscle Contraction

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Associated diseases

Unknown
Disease merge term	Disease name	Evidence	References	Source
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Carpal Tunnel Syndrome	Carpal tunnel syndrome	N/A	N/A	GWAS
Hypertension	Hypertension	N/A	N/A	GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Androgen Insensitivity Syndrome	Associate	25313366
Arrhythmogenic Right Ventricular Dysplasia	Associate	27613243
Bipolar Disorder	Stimulate	31695175
Carcinoma Hepatocellular	Associate	32951492, 36212176, 37149115
Carcinoma Hepatocellular	Stimulate	37603520
Carcinoma Pancreatic Ductal	Associate	40520021
Cardiomyopathies	Associate	27613243
Cartilage Diseases	Associate	9741315
Colorectal Neoplasms	Associate	24737953
Death	Associate	18224668
Fuchs' Endothelial Dystrophy	Stimulate	28726551
Glioblastoma	Associate	32634050
Heredodegenerative Disorders Nervous System	Associate	40106490
Lymphatic Metastasis	Associate	18224668, 25472585
Lysosomal Storage Diseases	Associate	40106490
Melanoma	Associate	10684289
Neoplasm Metastasis	Stimulate	24737953
Neoplasm Metastasis	Associate	33379338
Neoplasms	Associate	16838325, 24737953, 31882647, 34155195, 40520021
Neurodegenerative Diseases	Associate	40106490
Niemann Pick Disease Type C	Associate	40106490
Obesity	Associate	26213922, 34248836
Pancreatic Neoplasms	Associate	33073486, 33591944
Parkinson Disease	Associate	33021140
Pigmentation Disorders	Associate	38478639
Polycystic Ovary Syndrome	Associate	24279306
Respiratory Hypersensitivity	Associate	23984888
Sarcoma	Associate	38478639
Schizophrenia	Stimulate	31695175
Squamous Cell Carcinoma of Head and Neck	Associate	18224668, 24769516
Stomach Neoplasms	Associate	21931799, 25472585, 33178362, 39394072
Tertiary Lymphoid Structures	Stimulate	24737953
Triple Negative Breast Neoplasms	Associate	31882647
Warts	Associate	31569353