Gene Gene information from NCBI Gene database.
Entrez ID 3652
Gene name Intracisternal A particle-promoted polypeptide
Gene symbol IPP
Synonyms (NCBI Gene)
KLHL27
Chromosome 1
Chromosome location 1p34.1
Summary The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provi
miRNA miRNA information provided by mirtarbase database.
439
miRTarBase ID miRNA Experiments Reference
MIRT030826 hsa-miR-21-5p Microarray 18591254
MIRT046572 hsa-miR-222-3p CLASH 23622248
MIRT691633 hsa-miR-106a-5p HITS-CLIP 23313552
MIRT691632 hsa-miR-106b-5p HITS-CLIP 23313552
MIRT691631 hsa-miR-17-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0003779 Function Actin binding IEA
GO:0003779 Function Actin binding TAS 10072760
GO:0005515 Function Protein binding IPI 32296183
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
147485 6108 ENSG00000197429
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y573
Protein name Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)
Protein function May play a role in organizing the actin cytoskeleton.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00651 BTB 27 134 BTB/POZ domain Domain
PF07707 BACK 139 241 BTB And C-terminal Kelch Domain
PF01344 Kelch_1 287 330 Kelch motif Repeat
PF01344 Kelch_1 332 377 Kelch motif Repeat
PF01344 Kelch_1 379 424 Kelch motif Repeat
PF01344 Kelch_1 426 472 Kelch motif Repeat
PF01344 Kelch_1 474 520 Kelch motif Repeat
PF01344 Kelch_1 522 573 Kelch motif Repeat
Sequence
Sequence length 584
Interactions View interactions