Gene Gene information from NCBI Gene database.
Entrez ID 3625
Gene name Inhibin subunit beta B
Gene symbol INHBB
Synonyms (NCBI Gene)
-
Chromosome 2
Chromosome location 2q14.2
Summary This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activa
miRNA miRNA information provided by mirtarbase database.
484
miRTarBase ID miRNA Experiments Reference
MIRT018821 hsa-miR-335-5p Microarray 18185580
MIRT054468 hsa-miR-34a-5p Luciferase reporter assayqRT-PCRWestern blot 24446339
MIRT1066474 hsa-miR-105 CLIP-seq
MIRT1066475 hsa-miR-1207-3p CLIP-seq
MIRT1066476 hsa-miR-1207-5p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
53
GO ID Ontology Definition Evidence Reference
GO:0001541 Process Ovarian follicle development NAS 12790766
GO:0005125 Function Cytokine activity IBA
GO:0005125 Function Cytokine activity TAS 3122219
GO:0005179 Function Hormone activity IEA
GO:0005179 Function Hormone activity TAS 3122219
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
147390 6067 ENSG00000163083
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P09529
Protein name Inhibin beta B chain (Activin beta-B chain)
Protein function Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonad
PDB 7U5O
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00688 TGFb_propeptide 61 278 TGF-beta propeptide Family
PF00019 TGF_beta 302 406 Transforming growth factor beta like domain Domain
Sequence
Sequence length 407
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Signaling pathways regulating pluripotency of stem cells
  Signaling by Activin
Glycoprotein hormones
Antagonism of Activin by Follistatin