IL13RA1 (interleukin 13 receptor subunit alpha 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 3597 |
| Gene name | Interleukin 13 receptor subunit alpha 1 |
| Gene symbol | IL13RA1 |
| Synonyms (NCBI Gene) |
CD213A1CT19IL-13RaNR4
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| Chromosome | X |
| Chromosome location | Xq24 |
| Summary | The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 rece |
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miRNA
miRNA information provided by mirtarbase database.
370
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
13
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P78552 | |||||||||||||||
| Protein name | Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1) | |||||||||||||||
| Protein function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but canno | |||||||||||||||
| PDB | 3BPN , 3BPO , 4HWB , 5E4E | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. | |||||||||||||||
| Sequence |
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| Sequence length | 427 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
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