IL2RG (interleukin 2 receptor subunit gamma)

Gene

• Entrez ID: 3561
• Gene name: Interleukin 2 receptor subunit gamma
• Gene symbol: IL2RG
• Synonyms (NCBI Gene): CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1
• Chromosome: X
• Chromosome location: Xq13.1
• Summary: The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs111033618	G>A	Pathogenic	Coding sequence variant, missense variant
rs111033619	A>T	Pathogenic	Coding sequence variant, stop gained
rs111033620	C>T	Pathogenic	Coding sequence variant, missense variant
rs111033621	A>T	Pathogenic	Coding sequence variant, missense variant
rs111033622	A>G	Pathogenic	Coding sequence variant, missense variant
rs137852507	T>A,G	Pathogenic	Coding sequence variant, stop gained, missense variant
rs137852511	A>G	Pathogenic	Coding sequence variant, missense variant
rs193922346	C>A	Likely-pathogenic, pathogenic	Splice acceptor variant
rs193922347	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs193922348	A>C,G	Pathogenic, pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs193922349	A>G	Likely-pathogenic	Missense variant, coding sequence variant
rs193922350	C>T	Likely-pathogenic	Coding sequence variant, stop gained
rs587776729	->CCAATGCTG	Pathogenic	Inframe insertion, coding sequence variant
rs775704953	G>A,T	Benign, pathogenic	Coding sequence variant, missense variant, stop gained
rs776710796	T>C	Likely-pathogenic	Coding sequence variant, missense variant
rs869320658	G>A	Pathogenic	Missense variant, coding sequence variant
rs869320659	G>A	Pathogenic	Missense variant, coding sequence variant
rs869320660	C>T	Pathogenic	Missense variant, coding sequence variant
rs879253742	A>G	Likely-pathogenic	Missense variant, coding sequence variant
rs886039387	T>C	Pathogenic	Intron variant
rs886041334	A>G	Pathogenic	Initiator codon variant, missense variant
rs1057517747	G>A	Pathogenic	Coding sequence variant, stop gained
rs1057517950	A>G	Likely-pathogenic	Missense variant, coding sequence variant
rs1057520644	C>T	Likely-pathogenic, pathogenic	Missense variant, coding sequence variant
rs1057521062	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs1064793153	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs1064793338	C>-	Pathogenic	Frameshift variant, coding sequence variant
rs1131691652	G>A	Pathogenic	Coding sequence variant, stop gained
rs1556330234	C>T	Pathogenic	Stop gained, coding sequence variant
rs1556330249	G>A	Pathogenic	Stop gained, coding sequence variant
rs1556330286	G>C	Pathogenic	Stop gained, coding sequence variant
rs1556330552	G>A	Pathogenic	Stop gained, coding sequence variant
rs1556330562	A>-	Pathogenic	Frameshift variant, coding sequence variant
rs1556330568	C>T	Pathogenic	Stop gained, coding sequence variant
rs1556330710	T>-	Pathogenic	Frameshift variant, coding sequence variant
rs1556330713	G>A	Pathogenic	Stop gained, coding sequence variant
rs1556330755	C>T	Likely-pathogenic	Missense variant, coding sequence variant
rs1556330940	->CAGA	Pathogenic	Frameshift variant, coding sequence variant
rs1556330963	->CATGT	Pathogenic	Stop gained, coding sequence variant, inframe indel
rs1556331272	C>A	Pathogenic	Stop gained, coding sequence variant
rs1569479994	C>T	Likely-pathogenic	Coding sequence variant, stop gained
rs1569480018	C>T	Pathogenic	Splice donor variant
rs1569480047	C>T	Pathogenic	Coding sequence variant, stop gained
rs1569480082	G>A	Likely-pathogenic	Coding sequence variant, stop gained
rs1602289183	CA>-	Pathogenic	Coding sequence variant, splice donor variant, intron variant
rs1602289411	G>A	Pathogenic	Coding sequence variant, stop gained
rs1602289631	->AGCA	Pathogenic	Coding sequence variant, inframe indel, stop gained
rs1602289649	A>T	Likely-pathogenic	Coding sequence variant, missense variant
rs1602289943	C>-	Pathogenic	Coding sequence variant, frameshift variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT2015430	hsa-miR-4494	CLIP-seq
MIRT2015431	hsa-miR-4499	CLIP-seq
MIRT2015430	hsa-miR-4494	CLIP-seq
MIRT2015431	hsa-miR-4499	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
RXRA	Activation	12149223

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	TAS
GO:0004896	Function	Cytokine receptor activity	IBA	21873635
GO:0004911	Function	Interleukin-2 receptor activity	TAS	8266076
GO:0004913	Function	Interleukin-4 receptor activity	TAS	8266078
GO:0004917	Function	Interleukin-7 receptor activity	TAS	8266077
GO:0005515	Function	Protein binding	IPI	8266077, 12504082, 25416956, 31515488, 32296183
GO:0005768	Component	Endosome	TAS
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	TAS	8514792
GO:0006955	Process	Immune response	TAS	8266078
GO:0007165	Process	Signal transduction	NAS	8266076
GO:0009897	Component	External side of plasma membrane	IBA	21873635
GO:0009897	Component	External side of plasma membrane	ISS
GO:0009986	Component	Cell surface	IDA	15123770
GO:0016020	Component	Membrane	HDA	19946888
GO:0016032	Process	Viral process	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	IBA	21873635
GO:0019221	Process	Cytokine-mediated signaling pathway	TAS
GO:0019955	Function	Cytokine binding	IBA	21873635
GO:0019976	Function	Interleukin-2 binding	ISS
GO:0035723	Process	Interleukin-15-mediated signaling pathway	IMP	15123770
GO:0035723	Process	Interleukin-15-mediated signaling pathway	TAS
GO:0035771	Process	Interleukin-4-mediated signaling pathway	IEA
GO:0038110	Process	Interleukin-2-mediated signaling pathway	TAS
GO:0038111	Process	Interleukin-7-mediated signaling pathway	TAS
GO:0038113	Process	Interleukin-9-mediated signaling pathway	TAS
GO:0038114	Process	Interleukin-21-mediated signaling pathway	TAS
GO:0042010	Function	Interleukin-15 receptor activity	IDA	15123770
GO:0043235	Component	Receptor complex	IBA	21873635
GO:0050766	Process	Positive regulation of phagocytosis	IMP	15123770

Other IDs

• MIM: 308380
• HGNC: 6010
• e!Ensembl: ENSG00000147168

Protein

• UniProt ID: P31785
• Protein name: Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
• Protein function: Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770).
• PDB: 2B5I, 2ERJ, 3BPL, 3QAZ, 3QB7, 4GS7, 5M5E, 6OEL, 7S2R, 8ENT, 8EPA, 9JQT
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF09240	IL6Ra-bind	59 → 151	Interleukin-6 receptor alpha chain, binding	Domain

• Sequence:

  MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV
  QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK
  EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN
  HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW
  SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV
  TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP
  PCYTLKPET

• Sequence length: 369

Pathways

KEGG:

Cytokine-cytokine receptor interaction
Viral protein interaction with cytokine and cytokine receptor
Endocytosis
PI3K-Akt signaling pathway
JAK-STAT signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation
Measles
Human T-cell leukemia virus 1 infection
Pathways in cancer
Inflammatory bowel disease
Primary immunodeficiency

Reactome:

Interleukin-7 signaling
RAF/MAP kinase cascade
Interleukin-4 and Interleukin-13 signaling
Interleukin-15 signaling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-21 signaling
Interleukin receptor SHC signaling

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Agammaglobulinemia	Agammaglobulinemia	rs2134166251, rs128620183, rs128620185, rs128621193, rs128621201, rs128621204, rs121912424, rs267606711, rs376256147, rs281865422, rs1600631593, rs1555843601, rs267606871, rs879255271, rs2142904392, rs1555976766, rs1555977461, rs1555977580, rs1555977592, rs1555977598, rs1555978024, rs1555978197, rs1555978277, rs1555978891, rs1555980049, rs1555980799, rs1555980866, rs1554906579, rs1568801716, rs1565638431, rs2095906547, rs2095906404
Anemia	Anemia	rs118204044, rs118204045, rs118204046, rs121918330, rs869320719, rs869312029, rs121918332, rs869320724, rs767094129, rs786205058, rs786205059, rs137853119, rs137853120, rs137853121, rs1384933966, rs137853122, rs137853123, rs786205060, rs267607121, rs121908584, rs80338697, rs80338699, rs120074166, rs120074167, rs1050828, rs74575103, rs137852314, rs5030868, rs137852316, rs137852317, rs137852318, rs137852319, rs137852320, rs137852321, rs137852322, rs137852323, rs137852324, rs72554665, rs387906468, rs5030872, rs137852326, rs137852333, rs137852327, rs137852328, rs137852329, rs137852330, rs137852331, rs137852332, rs137852334, rs137852335, rs137852336, rs137852339, rs76645461, rs137852340, rs137852341, rs78478128, rs137852343, rs137852344, rs137852345, rs587776730, rs137852346, rs137852347, rs137852349, rs2070404412, rs2070350038, rs2070350009, rs137852303, rs137852304, rs33946267, rs34378160, rs33933298, rs11549407, rs35724775, rs34598529, rs41469945, rs267607201, rs80338694, rs80338696, rs387907018, rs398123546, rs78365220, rs587777100, rs587777101, rs483352840, rs869312752, rs765487627, rs1557229599, rs1557230040, rs1555524842, rs782090947, rs1358275550, rs1557229736, rs1557230573, rs1556323334, rs1233124208, rs1293528130, rs146864395, rs1595503440, rs1603411214, rs137852325, rs1575247302, rs1603411177, rs1336651679, rs782322505
Hypothyroidism	Hypothyroidism	rs869320723, rs121908862, rs121908863, rs121908865, rs121908866, rs121908867, rs121908870, rs121908871, rs121908872, rs2140110277, rs121908881, rs121908884, rs121908885, rs786205080, rs1586182912, rs121917847, rs104893655, rs104893657, rs104893658, rs104893659, rs104893660, rs104893656, rs121917719, rs786204790, rs189261858, rs879255608, rs868197660, rs879255609, rs1586744173, rs1586182837, rs771222349, rs1587618417, rs1601844140, rs760832986, rs780982673, rs1603336347, rs1691155605
Lymphoma	Lymphoma	rs11540652, rs1592119138, rs1592123162, rs1599367044
Lymphoproliferative disorder	Lymphoproliferative Disorders	rs121908191, rs398122933, rs397514667, rs397514260, rs397514261, rs748418658, rs781593353
Nephrotic syndrome	Nephrotic Syndrome	rs876657369, rs121912601, rs121912602, rs876657370, rs121912603, rs121912604, rs121912605, rs121907900, rs121907901, rs28941778, rs587776576, rs28942089, rs587776577, rs28941777, rs121907910, rs1568296260, rs119473033, rs74315342, rs74315343, rs74315345, rs74315346, rs74315347, rs74315348, rs121434394, rs267606919, rs121912488, rs267606953, rs267606954, rs267606955, rs104886210, rs1591732280, rs1591750243, rs140511594, rs140781106, rs147972030, rs587776969, rs386833863, rs386833880, rs386833882, rs386833892, rs386833895, rs386833909, rs386833911, rs386833920, rs386833935, rs386833947, rs1555763603, rs398122978, rs398122979, rs398122980, rs369573693, rs398122981, rs398122982, rs398122983, rs200482683, rs730882194, rs180177201, rs587777552, rs587777553, rs775170915, rs749740335, rs12568913, rs530318579, rs786204583, rs786204708, rs786204632, rs138656762, rs797044992, rs797044994, rs797044995, rs864321632, rs864321687, rs864321688, rs864321633, rs869025495, rs869025541, rs869312747, rs145473779, rs757674160, rs869320695, rs138909849, rs869312984, rs1057516900, rs763818901, rs199506378, rs1057517164, rs1057516523, rs1057516414, rs778055996, rs1057516395, rs1057516747, rs1057516880, rs1057516680, rs778217926, rs1057519347, rs764587648, rs1060499703, rs121907903, rs769259446, rs1131692252, rs1131692253, rs1131692254, rs1131692255, rs1131692256, rs746887949, rs1131692235, rs1135402911, rs1135402912, rs1135402913, rs1554946480, rs1555331969, rs773173317, rs1555816634, rs775006954, rs1320543506, rs534522842, rs1272948499, rs1191455921, rs1291398331, rs1554939785, rs776016942, rs1031744496, rs748812981, rs755972674, rs1553312833, rs967339926, rs1462028977, rs1212702104, rs1167223941, rs762631237, rs1553316575, rs1553315173, rs1553316648, rs1553316611, rs780761368, rs368572297, rs1568070817, rs1321552081, rs1558108130, rs1558091788, rs1565707103, rs1558355124, rs1564622701, rs1351580598, rs1589475328, rs1589413498, rs1572255744, rs1572262824, rs761410195, rs1602413491, rs1590326226, rs375998390, rs570583897, rs369363545, rs201488687, rs1334894971, rs763782471, rs138047529, rs895782232, rs1572255047, rs1589433172, rs1589509476, rs1572277600, rs1572282458, rs1584675898, rs759043857, rs1853443391
Schizophrenia	Schizophrenia, Chronic schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	24713359
Severe combined immunodeficiency disease	Severe Combined Immunodeficiency, Combined immunodeficiency, T-B+ severe combined immunodeficiency due to gamma chain deficiency	rs886037607, rs118203993, rs121908714, rs121908739, rs121908740, rs121908735, rs121908721, rs121908722, rs121908156, rs1564414523, rs1564418254, rs1564446526, rs786205074, rs121908157, rs121908159, rs786200884, rs397515357, rs104894562, rs137852624, rs137852625, rs137852626, rs137852627, rs137852507, rs137852509, rs111033619, rs111033620, rs1569480018, rs111033621, rs137852510, rs587776729, rs111033622, rs111033617, rs111033618, rs121917894, rs121917896, rs2133313409, rs121917897, rs28933392, rs104894282, rs104894283, rs104894285, rs121918570, rs121918572, rs730880318, rs104893674, rs730880319, rs104894453, rs104894454, rs104894451, rs137853206, rs777503956, rs267606645, rs267606648, rs397515390, rs193922346, rs193922347, rs193922348, rs193922349, rs193922350, rs137852508, rs193922640, rs193922641, rs193922643, rs193922645, rs193922361, rs193922364, rs193922464, rs148508754, rs193922574, rs113994174, rs606231246, rs397514671, rs397514686, rs397514755, rs199474679, rs199474685, rs199474686, rs199474681, rs150739647, rs267605358, rs886041036, rs587777335, rs587778405, rs145092287, rs587777562, rs606231256, rs200296680, rs786205456, rs786205517, rs774202259, rs786205615, rs878853261, rs786205890, rs782753385, rs746052951, rs869025224, rs869312857, rs869320660, rs869320659, rs869320658, rs879253742, rs886037924, rs886037925, rs750610248, rs886039394, rs761242509, rs886039387, rs886041043, rs886041044, rs886042051, rs886041333, rs749481781, rs1057517747, rs1057519506, rs1057523762, rs1057521062, rs1057520644, rs761583890, rs751635016, rs55729925, rs1064793248, rs1064793347, rs1064794027, rs781410769, rs1555524788, rs1486760100, rs769633203, rs1556330713, rs1555322558, rs1556330234, rs1556330755, rs1556329779, rs1556330552, rs1556329822, rs1556330286, rs1556331272, rs2146178281, rs376610445, rs757797994, rs775704953, rs1555743321, rs1564995660, rs1564995662, rs1556330249, rs144104577, rs886041796, rs1026474882, rs570768621, rs1556330562, rs1556330568, rs780014431, rs778343059, rs1555844617, rs1567629968, rs1567628757, rs1567629943, rs1567632864, rs1567632829, rs1567626023, rs1559328006, rs1561423197, rs1452483770, rs1568400897, rs1569479913, rs1568404443, rs1569480047, rs1563340753, rs368303189, rs1568431262, rs1568431102, rs1561424886, rs1602289943, rs1241698978, rs1569479994, rs1569480082, rs1602289649, rs1573261820, rs770985198, rs1589050343, rs1340132582, rs1589064324, rs1589070600, rs1213680890, rs149316157, rs1599873591, rs755706305, rs1602288051, rs1602289411, rs1602289183, rs1583513256, rs1589136659, rs1380154594, rs1011307501, rs1599876167, rs1569967422, rs1602289631, rs1573262398, rs760191638, rs1592117677, rs1640406042, rs372597855, rs1839558393, rs1839622622, rs1839957089, rs777008519, rs1233957241, rs2092261618, rs1839255008, rs1677695565, rs936493226, rs1162344514, rs991089005
Sezary syndrome	Sezary Syndrome	rs587776632	26551670
Combined immunodeficiency, x-linked	X-Linked Combined Immunodeficiency Diseases	rs137852510, rs111033618, rs869320659, rs869320658, rs1057520644, rs1064793347	7632950, 8299698, 16760466, 8961626, 8401490, 10794430, 7860773, 9399950, 9049783, 11129345, 2169613, 25869287, 7668284, 22039266, 9058718, 28747913, 7883965, 9150740, 8088810, 18641513, 23683512, 14966353, 21184155, 8900089, 7557965, 24534054, 8027558, 17598841, 11213805, 7937790

Unknown
Disease term	Disease name	Evidence	References	Source
Otitis media	Otitis Media			ClinVar
Omenn Syndrome	Omenn syndrome			GenCC

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma	Associate	32509861
Adrenoleukodystrophy	Associate	32072341
Agammaglobulinemia	Associate	33959125
Arthritis Reactive	Associate	32072341
Arthritis Rheumatoid	Associate	17257224
Arthritis Rheumatoid	Stimulate	24397353
Autoimmune Diseases	Associate	24406074, 31110501
Bone Diseases Metabolic	Associate	25565391
Breast Neoplasms	Associate	29685151
Carcinoma Adenoid Cystic	Associate	22382400
Carcinoma Renal Cell	Associate	10388747, 22363690, 37908350, 39233640, 9242704
Cardiomyopathy Dilated	Associate	36733486
Cataract	Associate	10914683, 18926820, 19262743, 24287181
Chagas Cardiomyopathy	Associate	17635814
Chromosome Disorders	Stimulate	12930384
Colitis Ulcerative	Associate	34353876
Crohn Disease	Associate	22128034, 40248067
Crohn Disease	Inhibit	40182599
Cystic Fibrosis	Associate	30177416
Dermatitis Atopic 3	Associate	34525985
Diabetes Mellitus Type 1	Associate	31110501
Diabetes Mellitus Type 2	Associate	26271466
Dysgammaglobulinemia	Associate	35052377
Eczema	Associate	34248995
Endometriosis	Associate	16759924
Genetic Diseases Inborn	Associate	35052377, 9633906
Glioblastoma	Associate	30152087
Glioma	Associate	30152087
Graft vs Host Disease	Associate	26444081
Granulomatous Disease Chronic	Associate	24406074
Growth Disorders	Associate	19189700
Hashimoto Disease	Associate	11045564, 32603365
Heart Diseases	Associate	17635814
Hereditary leiomyomatosis and renal cell cancer	Associate	18684866
HIV Infections	Stimulate	19864382
Hyperglycemia	Inhibit	31615064
Immune Deficiency Familial Variable	Associate	26076747
Immune System Diseases	Associate	11961146, 17827065, 37325673
Immunologic Deficiency Syndromes	Associate	24159173, 25565391, 7883965
Inflammation	Associate	32603365, 40248067
Inflammatory Bowel Diseases	Associate	37461086
Job Syndrome	Associate	34248995
Laryngeal Neoplasms	Associate	36033826
Leukemia Myeloid	Associate	33110919
Leukemia Prolymphocytic T Cell	Associate	24825865
Leukemia T Cell	Associate	18688285
Lipoma of the Conjunctiva	Associate	34349764
Lupus Erythematosus Systemic	Associate	17257224
Lymphohistiocytosis Hemophagocytic	Associate	10792291, 32993535
Lymphoma	Associate	15811959
Lymphoma T Cell	Associate	11902333
Lymphoma T Cell	Inhibit	40248067
Lymphoma T Cell Cutaneous	Associate	27329723
Lymphoma T Cell Peripheral	Associate	26536348
Melanoma	Associate	34159752
Meningococcal Infections	Associate	36033826
Necrosis	Associate	11902333
Neoplasm Metastasis	Associate	34159752
Neoplasms	Associate	22363690, 34349241, 34715892, 37841886, 9218839
Neoplasms	Inhibit	34159752
Neoplastic Syndromes Hereditary	Associate	24287181
Otitis Media with Effusion	Associate	22382400
Ovarian Neoplasms	Associate	37841886
Periodontitis	Associate	36438900
Pneumonia	Associate	23403317, 36799159
Premature Birth	Associate	23227263
Primary Immunodeficiency Diseases	Associate	31100039, 32265901
Progressive hearing loss stapes fixation	Associate	37461086
Renal Insufficiency	Associate	19189700
Severe Acute Respiratory Syndrome	Associate	25042067
Severe Combined Immunodeficiency	Associate	11961146, 12435740, 15831699, 17827065, 18559672, 19414857, 20149240, 26076747, 26547715, 28109013, 29728406, 30261899, 32265901, 32265911, 32754152, 33959125, 3478714, 35303369, 7668284, 7860773, 8317482, 8781427, 8916956, 9058718, 9446656, 9753072
Sezary Syndrome	Associate	26551670
Sjogren's Syndrome	Associate	34349764
Skin Neoplasms	Associate	32681206
Squamous Cell Carcinoma of Head and Neck	Associate	33232279
Tuberculosis	Associate	36799159
Warts	Associate	35052377
X Linked Combined Immunodeficiency Diseases	Associate	11260071, 11902333, 11961146, 12181059, 12435740, 1550118, 15585650, 17363735, 17369490, 18559672, 18688285, 18728247, 19189700, 19286997, 19398866, 22039266, 23403317, 24406074, 24853770, 25042067, 26444081, 26547715, 27099176, 30261899, 31100039, 32072341, 32681206, 32993535, 33959125, 34052995, 34248995, 35052377, 35764638, 36260239, 36553615, 36799159, 37461086, 7668284, 7860773, 7883965, 7937790, 8605322, 8605323, 8605324, 8704236, 8781427, 8916956, 9005984, 9054429, 9058718, 9633906, 9933465
Young Syndrome	Associate	34248995