IK (IK cytokine)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3550
Gene name Gene Name - the full gene name approved by the HGNC.
IK cytokine
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IK
Synonyms (NCBI Gene) Gene synonyms aliases
CSA2, RED, RER
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q31.3
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(5)
miRTarBase ID miRNA Experiments Reference
MIRT025539 hsa-miR-34a-5p Proteomics 21566225
MIRT048953 hsa-miR-92a-3p CLASH 23622248
MIRT040554 hsa-miR-92b-3p CLASH 23622248
MIRT2247169 hsa-miR-3674 CLIP-seq
MIRT2247170 hsa-miR-3978 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(16)
GO ID Ontology Definition Evidence Reference
GO:0000228 Component Nuclear chromosome IMP 24252166
GO:0000278 Process Mitotic cell cycle IMP 24252166
GO:0000398 Process MRNA splicing, via spliceosome IBA 21873635
GO:0000398 Process MRNA splicing, via spliceosome IDA 28781166
GO:0005515 Function Protein binding IPI 22190034, 22351768, 22365833, 24996188, 25416956, 28514442, 32296183, 32814053
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
600549 5958 ENSG00000113141
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q13123
Protein name Protein Red (Cytokine IK) (IK factor) (Protein RER)
Protein function Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166). Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mito
PDB 5O9Z , 6Q8I , 8QO9 , 8QZS
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07808 RED_N 76 → 302 RED-like protein N-terminal region Family
PF07807 RED_C 445 → 554 RED-like protein C-terminal region Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10216252}.
Sequence
Sequence length 557
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 24185611
Show/Hide Text Mining Associations (15)
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 14983485
Calcinosis Cutis Associate 14983485
Carcinogenesis Associate 9439149
Colonic Neoplasms Associate 10723572
Colorectal Neoplasms Associate 14687025, 21097699, 8030745, 8932328, 9342373
Colorectal Neoplasms Hereditary Nonpolyposis Associate 14983485
Liver Failure Associate 14983485
Lymphoma B Cell Associate 9163616
Lymphoma B Cell Marginal Zone Associate 8579126
Neoplasm Metastasis Associate 14983485