Gene Gene information from NCBI Gene database.
Entrez ID 353500
Gene name Bone morphogenetic protein 8a
Gene symbol BMP8A
Synonyms (NCBI Gene)
OP-2Op2
Chromosome 1
Chromosome location 1p34.3
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate
miRNA miRNA information provided by mirtarbase database.
477
miRTarBase ID miRNA Experiments Reference
MIRT021585 hsa-miR-142-3p Microarray 17612493
MIRT517421 hsa-miR-1910-3p PAR-CLIP 23446348
MIRT517420 hsa-miR-6511a-5p PAR-CLIP 23446348
MIRT517419 hsa-miR-25-3p PAR-CLIP 23446348
MIRT517418 hsa-miR-32-5p PAR-CLIP 23446348
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
GO ID Ontology Definition Evidence Reference
GO:0001503 Process Ossification IEA
GO:0002024 Process Diet induced thermogenesis IDA 22579288
GO:0005125 Function Cytokine activity IBA
GO:0005125 Function Cytokine activity IEA
GO:0005576 Component Extracellular region IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620847 21650 ENSG00000183682
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z5Y6
Protein name Bone morphogenetic protein 8A (BMP-8A)
Protein function Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation o
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00688 TGFb_propeptide 29 251 TGF-beta propeptide Family
PF00019 TGF_beta 300 401 Transforming growth factor beta like domain Domain
Sequence
Sequence length 402
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Hippo signaling pathway
Thermogenesis