GPR141 (G protein-coupled receptor 141)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 353345
Gene name G protein-coupled receptor 141
Gene symbol GPR141
Synonyms (NCBI Gene)
PGR13
Chromosome 7
Chromosome location 7p14.1
Summary GPR141 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
34
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (34)
miRTarBase ID miRNA Experiments Reference
MIRT563020 hsa-miR-5683 PAR-CLIP 20371350
MIRT563019 hsa-miR-6871-5p PAR-CLIP 20371350
MIRT563018 hsa-miR-205-3p PAR-CLIP 20371350
MIRT563017 hsa-miR-6729-3p PAR-CLIP 20371350
MIRT563016 hsa-miR-4740-3p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity IBA
GO:0004930 Function G protein-coupled receptor activity IEA
GO:0005515 Function Protein binding IPI 32814053
GO:0005886 Component Plasma membrane IEA
GO:0006954 Process Inflammatory response IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
609045 19997 ENSG00000187037
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z602
Protein name Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13)
Protein function Orphan receptor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 33 → 281 7 transmembrane receptor (rhodopsin family) Family
Sequence
Sequence length 305
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
7
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (7)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CHRONIC GRAFT VERSUS HOST DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LATE-ONSET ALZHEIMER'S DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (4)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Breast Neoplasms Associate 37204251
★★★★★
★☆☆☆☆
Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome Associate 37204251
★★★★★
★☆☆☆☆
Found in Text Mining only
Neoplasm Metastasis Associate 37204251
★★★★★
★☆☆☆☆
Found in Text Mining only
Neoplasms Associate 37204251
★★★★★
★☆☆☆☆
Found in Text Mining only