Gene Gene information from NCBI Gene database.
Entrez ID 353143
Gene name Late cornified envelope 3B
Gene symbol LCE3B
Synonyms (NCBI Gene)
LEP14
Chromosome 1
Chromosome location 1q21.3
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0008544 Process Epidermis development IEA
GO:0031424 Process Keratinization IEA
GO:0031640 Process Killing of cells of another organism IDA 28634035
GO:0050829 Process Defense response to Gram-negative bacterium IDA 28634035
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612614 29462 ENSG00000187238
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5TA77
Protein name Late cornified envelope protein 3B (Late envelope protein 14)
Protein function A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, bo
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14672 LCE 19 95 Late cornified envelope Family
Tissue specificity TISSUE SPECIFICITY: Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta. {ECO:0000269|PubMed:15854049}.
Sequence
Sequence length 95
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Formation of the cornified envelope