APOH (apolipoprotein H)

Gene

• Entrez ID: 350
• Gene name: Apolipoprotein H
• Gene symbol: APOH
• Synonyms (NCBI Gene): B2G1, B2GP1, BG
• Chromosome: 17
• Chromosome location: 17q24.2
• Summary: Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphos

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs398124629	T>C	Likely-pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017373	hsa-miR-335-5p	Microarray	18185580
MIRT621471	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT621470	hsa-miR-764	HITS-CLIP	23824327
MIRT621469	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT650871	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621468	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT621467	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT650870	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT621463	hsa-miR-640	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT621471	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT621470	hsa-miR-764	HITS-CLIP	23824327
MIRT621469	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT650871	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621468	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT621467	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT650870	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT621463	hsa-miR-640	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT634105	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT634104	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT634103	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT634102	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT634101	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT634100	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT634099	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT634098	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT634097	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT634096	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT634095	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT634094	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT634093	hsa-miR-302e	HITS-CLIP	23824327
MIRT634092	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT634091	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT634090	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT634089	hsa-miR-520b	HITS-CLIP	23824327
MIRT634088	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT634087	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT634086	hsa-miR-520e	HITS-CLIP	23824327
MIRT634085	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT634084	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT634083	hsa-miR-520h	HITS-CLIP	23824327
MIRT634082	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT634081	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT634080	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT634079	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT634078	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT634077	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT621471	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT621470	hsa-miR-764	HITS-CLIP	23824327
MIRT621469	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT621468	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT621467	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT621463	hsa-miR-640	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT621471	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT621470	hsa-miR-764	HITS-CLIP	23824327
MIRT621469	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT650871	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621468	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT621467	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT650870	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT621463	hsa-miR-640	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT621471	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT621470	hsa-miR-764	HITS-CLIP	23824327
MIRT621469	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT650871	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621468	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT621467	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT650870	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT621463	hsa-miR-640	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT634105	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT634104	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT634103	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT634102	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT634101	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT634100	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT634099	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT634098	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT634097	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT634096	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT634095	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT634094	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT634093	hsa-miR-302e	HITS-CLIP	23824327
MIRT634092	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT634091	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT634090	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT634089	hsa-miR-520b	HITS-CLIP	23824327
MIRT634088	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT634087	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT634086	hsa-miR-520e	HITS-CLIP	23824327
MIRT634085	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT634084	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT634083	hsa-miR-520h	HITS-CLIP	23824327
MIRT634082	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT634081	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT634080	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT634079	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT634078	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT634077	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT621471	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT621470	hsa-miR-764	HITS-CLIP	23824327
MIRT621469	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT621468	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT621467	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT621466	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT621465	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT621464	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT621463	hsa-miR-640	HITS-CLIP	23824327
MIRT621462	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT790067	hsa-miR-4504	CLIP-seq
MIRT790068	hsa-miR-542-3p	CLIP-seq
MIRT790069	hsa-miR-595	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001937	Process	Negative regulation of endothelial cell proliferation	IDA	17872974
GO:0005515	Function	Protein binding	IPI	9269765, 16480936, 19805618, 20223219, 32759297, 32814053
GO:0005543	Function	Phospholipid binding	IDA	15486070
GO:0005576	Component	Extracellular region	HDA	20551380
GO:0005576	Component	Extracellular region	HDA	27068509, 27559042
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	HDA	16502470, 20551380
GO:0005615	Component	Extracellular space	IDA	15486070
GO:0005615	Component	Extracellular space	IEA
GO:0007597	Process	Blood coagulation, intrinsic pathway	IDA	4052628
GO:0008201	Function	Heparin binding	IEA
GO:0008289	Function	Lipid binding	IDA	222615
GO:0009986	Component	Cell surface	IDA	16480936
GO:0010596	Process	Negative regulation of endothelial cell migration	IDA	17872974
GO:0016525	Process	Negative regulation of angiogenesis	IDA	17872974
GO:0030193	Process	Regulation of blood coagulation	IEA
GO:0030194	Process	Positive regulation of blood coagulation	TAS	16480936
GO:0030195	Process	Negative regulation of blood coagulation	IDA	4052628
GO:0031089	Component	Platelet dense granule lumen	TAS
GO:0031639	Process	Plasminogen activation	IDA	16480936
GO:0033033	Process	Negative regulation of myeloid cell apoptotic process	IDA	15534879
GO:0034197	Process	Triglyceride transport	ISS	7078428
GO:0034361	Component	Very-low-density lipoprotein particle	IDA	222615
GO:0034364	Component	High-density lipoprotein particle	IDA	222615
GO:0034371	Process	Chylomicron remodeling	IDA	7417307
GO:0034372	Process	Very-low-density lipoprotein particle remodeling	IDA	7417307
GO:0034392	Process	Negative regulation of smooth muscle cell apoptotic process	IDA	15534879
GO:0035473	Function	Lipase binding	IPI	7417307
GO:0042627	Component	Chylomicron	IDA	222615
GO:0042802	Function	Identical protein binding	IPI	18822289, 19805618
GO:0051917	Process	Regulation of fibrinolysis	IDA	16480936
GO:0051918	Process	Negative regulation of fibrinolysis	IDA	14726399
GO:0060230	Function	Lipoprotein lipase activator activity	IDA	7417307
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0090208	Process	Positive regulation of triglyceride metabolic process	IDA	7417307

Other IDs

• MIM: 138700
• HGNC: 616
• e!Ensembl: ENSG00000091583

Protein

• UniProt ID: P02749
• Protein name: Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)
• Protein function: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
• PDB: 1C1Z, 1G4F, 1G4G, 1QUB, 2KRI, 3OP8, 4JHS, 6V06, 6V08, 6V09, 6XSD, 6XST, 7JIK, 7KG4
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00084	Sushi	23 → 79	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	81 → 137	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	142 → 200	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	205 → 260	Sushi repeat (SCR repeat)	Domain
  PF09014	Sushi_2	261 → 345	Beta-2-glycoprotein-1 fifth domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma.
• Sequence:

  MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG
  MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD
  SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM
  FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL
  DGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC
  KNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC

• Sequence length: 345

Pathways

KEGG:

Cholesterol metabolism

Reactome:

Platelet degranulation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANTIPHOSPHOLIPID SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
APOH POLYMORPHISM	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ARTERIAL OCCLUSIVE DISEASES	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FAMILIAL LIPOPROTEIN LIPASE DEFICIENCY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-ALCOHOLIC FATTY LIVER DISEASE	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NONALCOHOLIC STEATOHEPATITIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Abortion Habitual	Associate	37243946	★☆☆☆☆ Found in Text Mining only
Abortion Spontaneous	Associate	37243946	★☆☆☆☆ Found in Text Mining only
Acute Aortic Syndrome	Associate	32256857	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Associate	35011591	★☆☆☆☆ Found in Text Mining only
Antiphospholipid Syndrome	Associate	10025920, 10366111, 10446865, 10643701, 11535526, 11711550, 11895785, 12235181, 12437660, 12571857, 12648080, 12871461, 15641049, 16472380, 17195232, 17223652, 20377996, 21255251, 21899894, 22106343, 22932793, 23811002, 24656088, 25027437, 25948765, 26576675, 28193831, 28667788, 29620217, 30923525, 31812994, 34107171, 35493489, 36012233, 36550078, 37243946, 9605162, 9933445	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Antiphospholipid Syndrome	Stimulate	12531807, 12780700, 26264622	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Atherosclerosis	Associate	20377996	★☆☆☆☆ Found in Text Mining only
Atrophy	Associate	35755170	★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Stimulate	24174712	★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Associate	10792380, 12437660, 19132787, 23279374, 9861005	★☆☆☆☆ Found in Text Mining only
Behcet Syndrome	Associate	34040049	★☆☆☆☆ Found in Text Mining only
Blood Coagulation Disorders	Associate	34232570	★☆☆☆☆ Found in Text Mining only
Blood Platelet Disorders	Inhibit	18654666, 23578283	★☆☆☆☆ Found in Text Mining only
Blood Platelet Disorders	Associate	34107171	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Inhibit	39291803	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	14984368, 17659677	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Associate	19132787	★☆☆☆☆ Found in Text Mining only
Carotid Artery Diseases	Associate	20377996	★☆☆☆☆ Found in Text Mining only
Carotid Artery Thrombosis	Associate	12571857	★☆☆☆☆ Found in Text Mining only
Carotid Stenosis	Associate	19132787	★☆☆☆☆ Found in Text Mining only
Central Nervous System Diseases	Associate	9933445	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Stimulate	35293591	★☆☆☆☆ Found in Text Mining only
Cholelithiasis	Associate	40428345	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Associate	21377902, 29669399	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Inhibit	22701550	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	30542696, 36101808	★☆☆☆☆ Found in Text Mining only
Corneal Endothelial Cell Loss	Stimulate	34221236	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Associate	23279374, 37686357	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COVID 19	Associate	34232570, 37371071	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Associate	34040049	★☆☆☆☆ Found in Text Mining only
Depressive Disorder	Associate	28667788	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Associate	28425473, 9377806	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Stimulate	37686357	★☆☆☆☆ Found in Text Mining only
Familial antiphospholipid syndrome	Associate	12648080, 12807892, 21255251	★☆☆☆☆ Found in Text Mining only
Fetal Diseases	Associate	15256379	★☆☆☆☆ Found in Text Mining only
Fibrosis	Inhibit	38027143	★☆☆☆☆ Found in Text Mining only
Guillain Barre Syndrome	Stimulate	20801190	★☆☆☆☆ Found in Text Mining only
HIV Seropositivity	Associate	34107171	★☆☆☆☆ Found in Text Mining only
Hydrocephalus Normal Pressure	Associate	34360799	★☆☆☆☆ Found in Text Mining only
Hyperlipoproteinemia Type II	Associate	12740481	★☆☆☆☆ Found in Text Mining only
Hyperlipoproteinemias	Associate	12740481	★☆☆☆☆ Found in Text Mining only
Hypoalphalipoproteinemias	Stimulate	26667175	★☆☆☆☆ Found in Text Mining only
Immunologic Deficiency Syndromes	Associate	12437660	★☆☆☆☆ Found in Text Mining only
Infectious Mononucleosis	Associate	10792380	★☆☆☆☆ Found in Text Mining only
Inflammation	Stimulate	17223652, 33355374, 34221236	★☆☆☆☆ Found in Text Mining only
Inflammation	Associate	20377996, 20801190, 23279374, 27228630, 28193831, 35293591	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Associate	21377902	★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Associate	38027143	★☆☆☆☆ Found in Text Mining only
Leukemia Monocytic Acute	Associate	21091668	★☆☆☆☆ Found in Text Mining only
Leukemia Prolymphocytic T Cell	Associate	8222331	★☆☆☆☆ Found in Text Mining only
Livedoid Vasculopathy	Associate	17223652	★☆☆☆☆ Found in Text Mining only
Liver Diseases	Associate	22932793	★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Associate	10366111, 12605674, 19132787, 22932793, 23214196, 28667788, 38609158	★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Stimulate	12780700, 29669399	★☆☆☆☆ Found in Text Mining only
Lupus Nephritis	Associate	19132787	★☆☆☆☆ Found in Text Mining only
Mouth Diseases	Associate	28193831	★☆☆☆☆ Found in Text Mining only
Mycosis Fungoides	Associate	33299887	★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Associate	10435722	★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	39291803	★☆☆☆☆ Found in Text Mining only
Neurologic Manifestations	Associate	21377902	★☆☆☆☆ Found in Text Mining only
Non alcoholic Fatty Liver Disease	Associate	35654975	★☆☆☆☆ Found in Text Mining only
Obesity	Associate	26711810, 28425473	★☆☆☆☆ Found in Text Mining only
Peritonitis	Associate	17223652	★☆☆☆☆ Found in Text Mining only
Placenta Diseases	Associate	15256379	★☆☆☆☆ Found in Text Mining only
Polyendocrinopathies Autoimmune	Associate	24819195, 35455968	★☆☆☆☆ Found in Text Mining only
Pregnancy Complications	Associate	12648080	★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Associate	28252112	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Associate	31920121	★☆☆☆☆ Found in Text Mining only
Respiratory Sounds	Associate	34538263	★☆☆☆☆ Found in Text Mining only
Seizures	Associate	21377902, 33532504	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	36430456	★☆☆☆☆ Found in Text Mining only
Thrombocytopenia	Inhibit	18654666	★☆☆☆☆ Found in Text Mining only
Thrombocytopenia Neonatal Alloimmune	Inhibit	18654666	★☆☆☆☆ Found in Text Mining only
Thrombophilia	Associate	25081279	★☆☆☆☆ Found in Text Mining only
Thrombosis	Associate	10366111, 12807892, 17223652, 22106343, 22932793, 23811002, 25081279, 30549270, 31812994, 34107171, 35293591, 8222331	★☆☆☆☆ Found in Text Mining only
Vasculitis	Associate	8222331	★☆☆☆☆ Found in Text Mining only
Venous Thrombosis	Associate	25081279	★☆☆☆☆ Found in Text Mining only