FAM131C (family with sequence similarity 131 member C)

Gene

• Entrez ID: 348487
• Gene name: Family with sequence similarity 131 member C
• Gene symbol: FAM131C
• Synonyms (NCBI Gene): C1orf117
• Chromosome: 1
• Chromosome location: 1p36.13

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017110	hsa-miR-335-5p	Microarray	18185580
MIRT980043	hsa-miR-3126-5p	CLIP-seq
MIRT980044	hsa-miR-3199	CLIP-seq
MIRT980045	hsa-miR-3689a-3p	CLIP-seq
MIRT980046	hsa-miR-3689c	CLIP-seq
MIRT980047	hsa-miR-4259	CLIP-seq
MIRT980048	hsa-miR-4425	CLIP-seq
MIRT980049	hsa-miR-4724-5p	CLIP-seq
MIRT980050	hsa-miR-4726-3p	CLIP-seq
MIRT980051	hsa-miR-4728-5p	CLIP-seq
MIRT980052	hsa-miR-4740-5p	CLIP-seq
MIRT980053	hsa-miR-571	CLIP-seq
MIRT1990359	hsa-miR-1343	CLIP-seq
MIRT2224564	hsa-miR-1273f	CLIP-seq
MIRT2224565	hsa-miR-143	CLIP-seq
MIRT980043	hsa-miR-3126-5p	CLIP-seq
MIRT2224566	hsa-miR-4419a	CLIP-seq
MIRT2224567	hsa-miR-4510	CLIP-seq
MIRT2224568	hsa-miR-4658	CLIP-seq
MIRT2224569	hsa-miR-4708-5p	CLIP-seq
MIRT980051	hsa-miR-4728-5p	CLIP-seq
MIRT2224570	hsa-miR-4758-5p	CLIP-seq
MIRT2224571	hsa-miR-4765	CLIP-seq
MIRT2224572	hsa-miR-4770	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 32296183, 32814053

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96AQ9
• Protein name: Protein FAM131C
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15010	FAM131	62 → 236	Putative cell signalling	Family

• Sequence:

  MGSCVSRDLFTSAHKNCPMPQGADPLNPDLPSGRTPTVAPDCVIGKDKQMDFCWDPWQRC
  FQTTNGYLSDSRSRPGNYNVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWS
  AQPAGWELSPAEDEHYCCLPDELREARFAAGVAEQFAITEATLSAWSSLDEEELHPENSP
  QGIVQLQDLESIYLQDSLPSGPSQDDSLQAFSSPSPSPDSCPSPEEPPSTAGIPQPPSPE
  LQHRRRLPGAQGPEGGTHPPGSLPSMDSGSLWEEDEVFYN

• Sequence length: 280

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-ALCOHOLIC FATTY LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations