NME9 (NME/NM23 family member 9)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
347736
Gene name Gene Name - the full gene name approved by the HGNC.
NME/NM23 family member 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NME9
Synonyms (NCBI Gene) Gene synonyms aliases
NM23-H9, NXL2, TXL-2, TXL2, TXNDC6
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q22.3
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(9)
GO ID Ontology Definition Evidence Reference
GO:0004550 Function Nucleoside diphosphate kinase activity IEA
GO:0005737 Component Cytoplasm IEA
GO:0005856 Component Cytoskeleton IEA
GO:0006183 Process GTP biosynthetic process IEA
GO:0006228 Process UTP biosynthetic process IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
618584 21343 ENSG00000181322
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q86XW9
Protein name Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2)
Protein function May be a regulator of microtubule physiology.
PDB 8J07
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00085 Thioredoxin 11 → 111 Thioredoxin Domain
PF00334 NDK 159 → 300 Nucleoside diphosphate kinase Domain
Tissue specificity TISSUE SPECIFICITY: Detected at very low levels in testis, lung and brain. {ECO:0000269|PubMed:12569107}.
Sequence
Sequence length 330
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (7)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis N/A N/A GWAS
Diabetes Type 2 diabetes N/A N/A GWAS
Dyslexia Dyslexia N/A N/A GWAS
Gout Gout N/A N/A GWAS
Show/Hide Text Mining Associations (5)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Colorectal Neoplasms Stimulate 23311631
Lymphoma Associate 33603952
Neoplasm Metastasis Associate 23311631
Neoplasms Stimulate 23311631
Testicular Diseases Associate 33603952