Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3475
Gene name Gene Name - the full gene name approved by the HGNC.
Interferon related developmental regulator 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IFRD1
Synonyms (NCBI Gene) Gene synonyms aliases
PC4, TIS7
Disease Acronyms (UniProt) Disease acronyms from UniProt database
PC4
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q31.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005143 hsa-miR-30a-5p pSILAC 18668040
MIRT001623 hsa-let-7b-5p pSILAC 18668040
MIRT001454 hsa-miR-16-5p pSILAC 18668040
MIRT026426 hsa-miR-192-5p Microarray 19074876
MIRT005143 hsa-miR-30a-5p Proteomics;Other 18668040
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA 21873635
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA 21873635
GO:0007275 Process Multicellular organism development IEA
GO:0007518 Process Myoblast fate determination TAS 7756174
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603502 5456 ENSG00000006652
Protein
UniProt ID O00458
Protein name Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)
Protein function Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05004 IFRD 42 347 Interferon-related developmental regulator (IFRD) Family
PF04836 IFRD_C 392 445 Interferon-related protein conserved region Family
Tissue specificity TISSUE SPECIFICITY: Expressed in a variety of tissues.
Sequence
Sequence length 451
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Nystagmus Nystagmus rs137852207, rs137852208, rs1928435502, rs137852209, rs137852210, rs1929191668, rs137852211, rs137852212, rs2124209414, rs387906720, rs387906721, rs1602791884, rs786205896
Spinocerebellar ataxia SPINOCEREBELLAR ATAXIA 18, Spinocerebellar ataxia type 18 rs80356538, rs80356539, rs56144125, rs28937887, rs80356544, rs80356540, rs80356542, rs1941485201, rs121918306, rs151344520, rs151344519, rs151344521, rs151344523, rs151344512, rs193922926
View all (203 more)
Unknown
Disease term Disease name Evidence References Source
Peripheral axonal neuropathy Peripheral axonal neuropathy ClinVar
Spinocerebellar Ataxia spinocerebellar ataxia type 18 GenCC
Associations from Text Mining
Disease Name Relationship Type References
Amyotrophic Lateral Sclerosis Associate 31118040
Asthma Associate 33150670
Ataxia Associate 19409521
Colorectal Neoplasms Associate 29094309
Disease Models Animal Associate 25939412
Heredodegenerative Disorders Nervous System Associate 19409521
Muscle Neoplasms Associate 25531450
Myelodysplastic Syndromes Associate 26010722
Neoplasms Associate 29094309
Osteoarthritis Hip Associate 25939412