IFRD1 (interferon related developmental regulator 1)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 3475
Gene name Interferon related developmental regulator 1
Gene symbol IFRD1
Synonyms (NCBI Gene)
PC4TIS7
Chromosome 7
Chromosome location 7q31.1
Summary This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development
miRNA miRNA information provided by mirtarbase database.
709
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (709)
miRTarBase ID miRNA Experiments Reference
MIRT005143 hsa-miR-30a-5p pSILAC 18668040
MIRT001623 hsa-let-7b-5p pSILAC 18668040
MIRT001454 hsa-miR-16-5p pSILAC 18668040
MIRT026426 hsa-miR-192-5p Microarray 19074876
MIRT005143 hsa-miR-30a-5p Proteomics;Other 18668040
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (15)
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
GO:0005737 Component Cytoplasm IEA
GO:0006357 Process Regulation of transcription by RNA polymerase II IEA
GO:0007518 Process Myoblast fate determination TAS 7756174
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
603502 5456 ENSG00000006652
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O00458
Protein name Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)
Protein function Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05004 IFRD 42 → 347 Interferon-related developmental regulator (IFRD) Family
PF04836 IFRD_C 392 → 445 Interferon-related protein conserved region Family
Tissue specificity TISSUE SPECIFICITY: Expressed in a variety of tissues.
Sequence
Sequence length 451
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
17
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (15)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Cervical cancer Likely benign rs565300368 RCV005922303
Charcot-Marie-Tooth disease Likely benign rs150651401 RCV000789967
Chronic lymphocytic leukemia/small lymphocytic lymphoma Benign rs61603869 RCV005868294
Clear cell carcinoma of kidney Benign rs61603869 RCV005868289
Show/Hide Text Mining Associations (13)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Amyotrophic Lateral Sclerosis Associate 31118040
Asthma Associate 33150670
Ataxia Associate 19409521
Colorectal Neoplasms Associate 29094309
Disease Models Animal Associate 25939412
Heredodegenerative Disorders Nervous System Associate 19409521
Muscle Neoplasms Associate 25531450
Myelodysplastic Syndromes Associate 26010722
Neoplasms Associate 29094309
Osteoarthritis Hip Associate 25939412