Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	345930
Gene name Gene Name - the full gene name approved by the HGNC.	Epithelial cell transforming 2 like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ECT2L
Synonyms (NCBI Gene) Gene synonyms aliases	ARHGEF32, C6orf91, FBXO49, LFDH, dJ509I19.2, dJ509I19.3, dJ509I19.5
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q24.1

Show/Hide all(156)

miRTarBase ID	miRNA	Experiments
MIRT951858	hsa-miR-1297	CLIP-seq
MIRT951859	hsa-miR-1305	CLIP-seq
MIRT951860	hsa-miR-26a	CLIP-seq
MIRT951861	hsa-miR-26b	CLIP-seq
MIRT951862	hsa-miR-4465	CLIP-seq
MIRT951863	hsa-miR-4670-3p	CLIP-seq
MIRT951864	hsa-miR-498	CLIP-seq
MIRT951865	hsa-miR-1227	CLIP-seq
MIRT951866	hsa-miR-1254	CLIP-seq
MIRT951867	hsa-miR-136	CLIP-seq
MIRT951868	hsa-miR-2467-5p	CLIP-seq
MIRT951869	hsa-miR-3116	CLIP-seq
MIRT951870	hsa-miR-3149	CLIP-seq
MIRT951871	hsa-miR-3188	CLIP-seq
MIRT951872	hsa-miR-3663-5p	CLIP-seq
MIRT951873	hsa-miR-3975	CLIP-seq
MIRT951874	hsa-miR-411	CLIP-seq
MIRT951875	hsa-miR-4316	CLIP-seq
MIRT951876	hsa-miR-4438	CLIP-seq
MIRT951877	hsa-miR-4690-5p	CLIP-seq
MIRT951878	hsa-miR-4710	CLIP-seq
MIRT951879	hsa-miR-4715-3p	CLIP-seq
MIRT951880	hsa-miR-4716-5p	CLIP-seq
MIRT951881	hsa-miR-4735-5p	CLIP-seq
MIRT951882	hsa-miR-4775	CLIP-seq
MIRT951883	hsa-miR-4781-3p	CLIP-seq
MIRT951884	hsa-miR-4792	CLIP-seq
MIRT951885	hsa-miR-4794	CLIP-seq
MIRT951886	hsa-miR-483-5p	CLIP-seq
MIRT951887	hsa-miR-485-5p	CLIP-seq
MIRT951888	hsa-miR-5095	CLIP-seq
MIRT951889	hsa-miR-515-5p	CLIP-seq
MIRT951890	hsa-miR-590-3p	CLIP-seq
MIRT951891	hsa-miR-661	CLIP-seq
MIRT1981878	hsa-miR-130a	CLIP-seq
MIRT1981879	hsa-miR-130b	CLIP-seq
MIRT1981880	hsa-miR-301a	CLIP-seq
MIRT1981881	hsa-miR-301b	CLIP-seq
MIRT1981882	hsa-miR-3616-5p	CLIP-seq
MIRT1981883	hsa-miR-3647-5p	CLIP-seq
MIRT1981884	hsa-miR-3666	CLIP-seq
MIRT1981885	hsa-miR-3929	CLIP-seq
MIRT1981886	hsa-miR-4295	CLIP-seq
MIRT1981887	hsa-miR-4419b	CLIP-seq
MIRT1981888	hsa-miR-4478	CLIP-seq
MIRT1981889	hsa-miR-454	CLIP-seq
MIRT1981890	hsa-miR-4795-5p	CLIP-seq
MIRT1981891	hsa-miR-494	CLIP-seq
MIRT1981892	hsa-miR-519a	CLIP-seq
MIRT1981893	hsa-miR-519b-3p	CLIP-seq
MIRT1981894	hsa-miR-519c-3p	CLIP-seq
MIRT1981895	hsa-miR-573	CLIP-seq
MIRT2216776	hsa-miR-106a	CLIP-seq
MIRT2216777	hsa-miR-106b	CLIP-seq
MIRT1981878	hsa-miR-130a	CLIP-seq
MIRT1981879	hsa-miR-130b	CLIP-seq
MIRT2216778	hsa-miR-150	CLIP-seq
MIRT2216779	hsa-miR-17	CLIP-seq
MIRT2216780	hsa-miR-20a	CLIP-seq
MIRT2216781	hsa-miR-20b	CLIP-seq
MIRT951868	hsa-miR-2467-5p	CLIP-seq
MIRT1981880	hsa-miR-301a	CLIP-seq
MIRT1981881	hsa-miR-301b	CLIP-seq
MIRT951871	hsa-miR-3188	CLIP-seq
MIRT1981882	hsa-miR-3616-5p	CLIP-seq
MIRT1981883	hsa-miR-3647-5p	CLIP-seq
MIRT951872	hsa-miR-3663-5p	CLIP-seq
MIRT1981884	hsa-miR-3666	CLIP-seq
MIRT2216782	hsa-miR-371-5p	CLIP-seq
MIRT2216783	hsa-miR-371b-5p	CLIP-seq
MIRT1981885	hsa-miR-3929	CLIP-seq
MIRT951873	hsa-miR-3975	CLIP-seq
MIRT1981886	hsa-miR-4295	CLIP-seq
MIRT951875	hsa-miR-4316	CLIP-seq
MIRT1981887	hsa-miR-4419b	CLIP-seq
MIRT2216784	hsa-miR-4464	CLIP-seq
MIRT1981888	hsa-miR-4478	CLIP-seq
MIRT1981889	hsa-miR-454	CLIP-seq
MIRT951878	hsa-miR-4710	CLIP-seq
MIRT951880	hsa-miR-4716-5p	CLIP-seq
MIRT2216785	hsa-miR-4748	CLIP-seq
MIRT951883	hsa-miR-4781-3p	CLIP-seq
MIRT951884	hsa-miR-4792	CLIP-seq
MIRT1981890	hsa-miR-4795-5p	CLIP-seq
MIRT951887	hsa-miR-485-5p	CLIP-seq
MIRT1981892	hsa-miR-519a	CLIP-seq
MIRT1981893	hsa-miR-519b-3p	CLIP-seq
MIRT1981894	hsa-miR-519c-3p	CLIP-seq
MIRT2216786	hsa-miR-519d	CLIP-seq
MIRT2216787	hsa-miR-520g	CLIP-seq
MIRT2216788	hsa-miR-520h	CLIP-seq
MIRT1981895	hsa-miR-573	CLIP-seq
MIRT2216789	hsa-miR-93	CLIP-seq
MIRT951866	hsa-miR-1254	CLIP-seq
MIRT951869	hsa-miR-3116	CLIP-seq
MIRT951870	hsa-miR-3149	CLIP-seq
MIRT951874	hsa-miR-411	CLIP-seq
MIRT951879	hsa-miR-4715-3p	CLIP-seq
MIRT951881	hsa-miR-4735-5p	CLIP-seq
MIRT951882	hsa-miR-4775	CLIP-seq
MIRT951885	hsa-miR-4794	CLIP-seq
MIRT951886	hsa-miR-483-5p	CLIP-seq
MIRT951890	hsa-miR-590-3p	CLIP-seq
MIRT951891	hsa-miR-661	CLIP-seq
MIRT951866	hsa-miR-1254	CLIP-seq
MIRT951869	hsa-miR-3116	CLIP-seq
MIRT951870	hsa-miR-3149	CLIP-seq
MIRT951874	hsa-miR-411	CLIP-seq
MIRT951879	hsa-miR-4715-3p	CLIP-seq
MIRT951881	hsa-miR-4735-5p	CLIP-seq
MIRT951882	hsa-miR-4775	CLIP-seq
MIRT951885	hsa-miR-4794	CLIP-seq
MIRT951886	hsa-miR-483-5p	CLIP-seq
MIRT951890	hsa-miR-590-3p	CLIP-seq
MIRT951891	hsa-miR-661	CLIP-seq
MIRT951865	hsa-miR-1227	CLIP-seq
MIRT951866	hsa-miR-1254	CLIP-seq
MIRT951867	hsa-miR-136	CLIP-seq
MIRT951869	hsa-miR-3116	CLIP-seq
MIRT951870	hsa-miR-3149	CLIP-seq
MIRT951874	hsa-miR-411	CLIP-seq
MIRT951876	hsa-miR-4438	CLIP-seq
MIRT951878	hsa-miR-4710	CLIP-seq
MIRT951879	hsa-miR-4715-3p	CLIP-seq
MIRT951880	hsa-miR-4716-5p	CLIP-seq
MIRT951881	hsa-miR-4735-5p	CLIP-seq
MIRT951882	hsa-miR-4775	CLIP-seq
MIRT951883	hsa-miR-4781-3p	CLIP-seq
MIRT951884	hsa-miR-4792	CLIP-seq
MIRT951885	hsa-miR-4794	CLIP-seq
MIRT951886	hsa-miR-483-5p	CLIP-seq
MIRT951888	hsa-miR-5095	CLIP-seq
MIRT951889	hsa-miR-515-5p	CLIP-seq
MIRT951890	hsa-miR-590-3p	CLIP-seq
MIRT951891	hsa-miR-661	CLIP-seq
MIRT951865	hsa-miR-1227	CLIP-seq
MIRT951866	hsa-miR-1254	CLIP-seq
MIRT951867	hsa-miR-136	CLIP-seq
MIRT951869	hsa-miR-3116	CLIP-seq
MIRT951870	hsa-miR-3149	CLIP-seq
MIRT951874	hsa-miR-411	CLIP-seq
MIRT951875	hsa-miR-4316	CLIP-seq
MIRT951876	hsa-miR-4438	CLIP-seq
MIRT951878	hsa-miR-4710	CLIP-seq
MIRT951879	hsa-miR-4715-3p	CLIP-seq
MIRT951880	hsa-miR-4716-5p	CLIP-seq
MIRT951881	hsa-miR-4735-5p	CLIP-seq
MIRT951882	hsa-miR-4775	CLIP-seq
MIRT951883	hsa-miR-4781-3p	CLIP-seq
MIRT951884	hsa-miR-4792	CLIP-seq
MIRT951885	hsa-miR-4794	CLIP-seq
MIRT951886	hsa-miR-483-5p	CLIP-seq
MIRT951888	hsa-miR-5095	CLIP-seq
MIRT951889	hsa-miR-515-5p	CLIP-seq
MIRT951890	hsa-miR-590-3p	CLIP-seq
MIRT951891	hsa-miR-661	CLIP-seq

Show/Hide all(1)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q008S8

Protein name

Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH)

Protein function

May act as a guanine nucleotide exchange factor (GEF).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12937	F-box-like	79 → 124	F-box-like	Domain
PF14252	DUF4347	290 → 460	Domain of unknown function (DUF4347)	Family
PF00621	RhoGEF	570 → 752	RhoGEF domain	Domain

Sequence

MESFHTRFSAWTPFSNKSLNRQLFQERVALISHWFDLWTNKQRQEFLFAIFLRCTKSQLR
FVQDWFSERMQVAKVDFSTVLPRFISLYIFSFLSPKDLCAAAQVSWPWKFLTEQDCLWMP
KCVKFGWFLPYTPTDNEYGAWKRHYIACVSHLDWLTPREAAATYGTLNEPKTEDEELLER
QREKCLRKRIWEKIALRKKELFKVRPPWVSGTCCSSVLKPRCQPRLSQTVRERVGLHEAL
EKQLVLTSLETLPKRSNISGSHSYPLLSKKNWHGVHKNDDRSSYALRPHFMLISSRIPAY
EMVMESVKAGVVSVVYEHSVTLESLLYLIEKALDGQKAQSIGIFSDGDSREINLLQGYKI
GVKNLLRPEVRDFWEKLGSYVATEEEGGHVDFFVPLGASEAGIEVLSQLSQLTGTFFTAP
TGIATGSYQHILSDWLGSQWGKAPSSIYFCESKLQTWSSFTDFLEETLKTVRKQLYPFFK
ELQKSISGRMIGQFMFDTMGMTNILNNQDTAQALADGLMELSKEDSERNVVEDNSWDTKS
RLSKNDLNFEALINLERILQKDSAEKRARVVRELLQSERKYVQILEIVRDVYVAPLKAAL
SSNRAILSAANIQIIFCDILQILSLNRQFLDNLRDRLQEWGPAHCVGEIVTKFGSQLNTY
TNFFNNYPVILKTIEKCREMIPAFRTFLKRHDKTIVTKMLSLPELLLYPSRRFEEYLNLL
YAVRLHTPAEHVDRGDLTTAIDQIKKYKGYIDQMKQNITMKDHLSDIQRIIWGCPTLSEV
NRYLIRVQDVAQLHCCDEEISFSLRLYEHIHDLSLFLFNDALLVSSRGTSHTPFERTSKT
TYQFIASVALHRLLIENIPDSKYVKNAFILQGPKYKWICATEIEDDKFLWLSVLRNAIKS
SMEK

Sequence length

904

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	36344993
Neoplasms	Associate	30865299
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	22237106
Spastic Paraplegia Hereditary	Associate	36344993

ECT2L (epithelial cell transforming 2 like)