SLC10A6 (solute carrier family 10 member 6)

Gene

• Entrez ID: 345274
• Gene name: Solute carrier family 10 member 6
• Gene symbol: SLC10A6
• Synonyms (NCBI Gene): SOAT
• Chromosome: 4
• Chromosome location: 4q21.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT699495	hsa-miR-302f	HITS-CLIP	23313552
MIRT699494	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT699493	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT699492	hsa-miR-940	HITS-CLIP	23313552
MIRT699491	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT699490	hsa-miR-4667-5p	HITS-CLIP	23313552
MIRT699489	hsa-miR-4700-5p	HITS-CLIP	23313552
MIRT699487	hsa-miR-8089	HITS-CLIP	23313552
MIRT699488	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT699486	hsa-miR-1253	HITS-CLIP	23313552
MIRT699485	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT699484	hsa-miR-4434	HITS-CLIP	23313552
MIRT699482	hsa-miR-4516	HITS-CLIP	23313552
MIRT699483	hsa-miR-5703	HITS-CLIP	23313552
MIRT699481	hsa-miR-3175	HITS-CLIP	23313552
MIRT699480	hsa-miR-1343-5p	HITS-CLIP	23313552
MIRT699479	hsa-miR-939-5p	HITS-CLIP	23313552
MIRT699478	hsa-miR-6825-5p	HITS-CLIP	23313552
MIRT699477	hsa-miR-1273e	HITS-CLIP	23313552
MIRT699476	hsa-miR-3150a-3p	HITS-CLIP	23313552
MIRT699475	hsa-miR-6763-5p	HITS-CLIP	23313552
MIRT672383	hsa-miR-665	HITS-CLIP	23313552
MIRT685445	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT685444	hsa-miR-193a-3p	HITS-CLIP	23313552
MIRT685443	hsa-miR-193b-3p	HITS-CLIP	23313552
MIRT685442	hsa-miR-4463	HITS-CLIP	23313552
MIRT685441	hsa-miR-3675-3p	HITS-CLIP	23313552
MIRT685440	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT685439	hsa-miR-3926	HITS-CLIP	23313552
MIRT685438	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT685437	hsa-miR-548s	HITS-CLIP	23313552
MIRT677518	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT677517	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT677516	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT677515	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT677514	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT677513	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT677512	hsa-miR-1281	HITS-CLIP	23824327
MIRT677511	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT677510	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT677509	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT677508	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT677507	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT677506	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT677505	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT677504	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT677503	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT677502	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT677501	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT672424	hsa-miR-3929	HITS-CLIP	23824327
MIRT672423	hsa-miR-4419b	HITS-CLIP	23824327
MIRT672422	hsa-miR-4478	HITS-CLIP	23824327
MIRT672421	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT672420	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT672419	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT672418	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT672417	hsa-miR-7112-5p	HITS-CLIP	23824327
MIRT672416	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT672415	hsa-miR-4786-5p	HITS-CLIP	23824327
MIRT672414	hsa-miR-769-5p	HITS-CLIP	23824327
MIRT672413	hsa-miR-3197	HITS-CLIP	23824327
MIRT672412	hsa-miR-6087	HITS-CLIP	23824327
MIRT672411	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT672410	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT672409	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT672408	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT672407	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT672406	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT672405	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT672404	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT672403	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT672402	hsa-miR-7977	HITS-CLIP	23824327
MIRT672401	hsa-miR-3672	HITS-CLIP	23824327
MIRT672400	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT672399	hsa-miR-6765-5p	HITS-CLIP	23824327
MIRT672398	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT672397	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT672396	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT672395	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT672394	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT672393	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT672392	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT672391	hsa-miR-3689c	HITS-CLIP	23824327
MIRT672390	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT672389	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT672388	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT672387	hsa-miR-3122	HITS-CLIP	23824327
MIRT672386	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT672385	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT672384	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT672383	hsa-miR-665	HITS-CLIP	23824327
MIRT699495	hsa-miR-302f	HITS-CLIP	23313552
MIRT699494	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT699493	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT699492	hsa-miR-940	HITS-CLIP	23313552
MIRT699491	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT699490	hsa-miR-4667-5p	HITS-CLIP	23313552
MIRT699489	hsa-miR-4700-5p	HITS-CLIP	23313552
MIRT699487	hsa-miR-8089	HITS-CLIP	23313552
MIRT699488	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT699486	hsa-miR-1253	HITS-CLIP	23313552
MIRT699485	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT699484	hsa-miR-4434	HITS-CLIP	23313552
MIRT699482	hsa-miR-4516	HITS-CLIP	23313552
MIRT699483	hsa-miR-5703	HITS-CLIP	23313552
MIRT699481	hsa-miR-3175	HITS-CLIP	23313552
MIRT699480	hsa-miR-1343-5p	HITS-CLIP	23313552
MIRT699479	hsa-miR-939-5p	HITS-CLIP	23313552
MIRT699478	hsa-miR-6825-5p	HITS-CLIP	23313552
MIRT699477	hsa-miR-1273e	HITS-CLIP	23313552
MIRT699476	hsa-miR-3150a-3p	HITS-CLIP	23313552
MIRT699475	hsa-miR-6763-5p	HITS-CLIP	23313552
MIRT672383	hsa-miR-665	HITS-CLIP	23313552
MIRT685445	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT685444	hsa-miR-193a-3p	HITS-CLIP	23313552
MIRT685443	hsa-miR-193b-3p	HITS-CLIP	23313552
MIRT685442	hsa-miR-4463	HITS-CLIP	23313552
MIRT685441	hsa-miR-3675-3p	HITS-CLIP	23313552
MIRT685440	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT685439	hsa-miR-3926	HITS-CLIP	23313552
MIRT685438	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT685437	hsa-miR-548s	HITS-CLIP	23313552
MIRT677518	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT677517	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT677516	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT677515	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT677514	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT677513	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT677512	hsa-miR-1281	HITS-CLIP	23824327
MIRT677511	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT677510	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT677509	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT677508	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT677507	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT677506	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT677505	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT677504	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT677503	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT677502	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT677501	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT672424	hsa-miR-3929	HITS-CLIP	23824327
MIRT672423	hsa-miR-4419b	HITS-CLIP	23824327
MIRT672422	hsa-miR-4478	HITS-CLIP	23824327
MIRT672421	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT672420	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT672419	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT672418	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT672417	hsa-miR-7112-5p	HITS-CLIP	23824327
MIRT672416	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT672415	hsa-miR-4786-5p	HITS-CLIP	23824327
MIRT672414	hsa-miR-769-5p	HITS-CLIP	23824327
MIRT672413	hsa-miR-3197	HITS-CLIP	23824327
MIRT672412	hsa-miR-6087	HITS-CLIP	23824327
MIRT672411	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT672410	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT672409	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT672408	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT672407	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT672406	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT672405	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT672404	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT672403	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT672402	hsa-miR-7977	HITS-CLIP	23824327
MIRT672401	hsa-miR-3672	HITS-CLIP	23824327
MIRT672400	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT672399	hsa-miR-6765-5p	HITS-CLIP	23824327
MIRT672398	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT672397	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT672396	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT672395	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT672394	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT672393	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT672392	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT672391	hsa-miR-3689c	HITS-CLIP	23824327
MIRT672390	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT672389	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT672388	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT672387	hsa-miR-3122	HITS-CLIP	23824327
MIRT672386	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT672385	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT672384	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT672383	hsa-miR-665	HITS-CLIP	23824327
MIRT1351658	hsa-miR-125a-5p	CLIP-seq
MIRT1351659	hsa-miR-125b	CLIP-seq
MIRT1351660	hsa-miR-203	CLIP-seq
MIRT1351661	hsa-miR-4319	CLIP-seq
MIRT1351662	hsa-miR-4732-3p	CLIP-seq
MIRT1351663	hsa-miR-515-5p	CLIP-seq
MIRT1351664	hsa-miR-548t	CLIP-seq
MIRT1351665	hsa-miR-670	CLIP-seq
MIRT2328400	hsa-miR-1207-3p	CLIP-seq
MIRT2328401	hsa-miR-193b	CLIP-seq
MIRT2328402	hsa-miR-3607-5p	CLIP-seq
MIRT2328403	hsa-miR-592	CLIP-seq
MIRT2328404	hsa-miR-597	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006814	Process	Sodium ion transport	IEA
GO:0006869	Process	Lipid transport	IEA
GO:0008508	Function	Bile acid:sodium symporter activity	IBA
GO:0008508	Function	Bile acid:sodium symporter activity	TAS
GO:0015293	Function	Symporter activity	IEA
GO:0015721	Process	Bile acid and bile salt transport	IBA
GO:0016020	Component	Membrane	IEA
GO:0043250	Function	Sodium-dependent organic anion transmembrane transporter activity	IEA
GO:0043251	Process	Sodium-dependent organic anion transport	IEA
GO:0055085	Process	Transmembrane transport	TAS

Other IDs

• MIM: 613366
• HGNC: 30603
• e!Ensembl: ENSG00000145283

Protein

• UniProt ID: Q3KNW5
• Protein name: Sodium-dependent organic anion transporter (SOAT) (Solute carrier family 10 member 6) (SLC10A6)
• Protein function: Transports sulfoconjugated steroid hormones from the extracellular compartment into the cytosol in a sodium-dependent manner without hydrolysis (PubMed:17491011, PubMed:23667501, PubMed:24717977, PubMed:28951227). Steroid sulfate hormones are co
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01758	SBF	39 → 217	Sodium Bile acid symporter family	Family

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in testis, placenta and pancreas. Moderately expressed in heart, lung and mammary gland. Weakly expressed in brain, colon, kidney, liver, ovary, prostate, small intestine, spleen and thymus. {ECO:0000269|PubMed:1749101
• Sequence:

  MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWS
  HIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVD
  GDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGV
  YVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVT
  GFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLID
  GFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGP
  MDCHRALEPVGHITSCE

• Sequence length: 377

Pathways

Reactome:

Transport of bile salts and organic acids, metal ions and amine compounds