Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3439
Gene name Gene Name - the full gene name approved by the HGNC.	Interferon alpha 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	IFNA1
Synonyms (NCBI Gene) Gene synonyms aliases	IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@, leIF D
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9p21.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral,

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miRTarBase ID	miRNA	Experiments	Reference
MIRT023373	hsa-miR-122-5p	Microarray	17612493
MIRT736415	hsa-miR-491-3p	qRT-PCR, Flow cytometry	33679688
MIRT1060624	hsa-miR-219-2-3p	CLIP-seq
MIRT1060625	hsa-miR-4535	CLIP-seq
MIRT1060626	hsa-miR-4776-5p	CLIP-seq
MIRT1060627	hsa-miR-4781-3p	CLIP-seq

Transcription factors

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GO ID	Ontology	Definition	Evidence	Reference
GO:0002250	Process	Adaptive immune response	IBA
GO:0002286	Process	T cell activation involved in immune response	IBA
GO:0002312	Process	B cell activation involved in immune response	IBA
GO:0002323	Process	Natural killer cell activation involved in immune response	IBA
GO:0005125	Function	Cytokine activity	IBA
GO:0005125	Function	Cytokine activity	IEA
GO:0005126	Function	Cytokine receptor binding	IEA
GO:0005132	Function	Type I interferon receptor binding	IBA
GO:0005132	Function	Type I interferon receptor binding	TAS	4057246
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IEA
GO:0006952	Process	Defense response	IEA
GO:0006959	Process	Humoral immune response	IBA
GO:0043330	Process	Response to exogenous dsRNA	IBA
GO:0046718	Process	Symbiont entry into host cell	IDA	3036369
GO:0051607	Process	Defense response to virus	IEA
GO:0060337	Process	Type I interferon-mediated signaling pathway	IBA
GO:0060337	Process	Type I interferon-mediated signaling pathway	IDA	1849076
GO:0060337	Process	Type I interferon-mediated signaling pathway	NAS	30936491
GO:0098586	Process	Cellular response to virus	NAS	30936491
GO:0140374	Process	Antiviral innate immune response	IDA	22948139
GO:0140374	Process	Antiviral innate immune response	IEP	25930096

MIM	HGNC	e!Ensembl
147660	5417	ENSG00000197919

	KEGG		Reactome
	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway Necroptosis Toll-like receptor signaling pathway NOD-like receptor signaling pathway RIG-I-like receptor signaling pathway Cytosolic DNA-sensing pathway JAK-STAT signaling pathway Natural killer cell mediated cytotoxicity Alcoholic liver disease Tuberculosis Hepatitis C Hepatitis B Measles Human cytomegalovirus infection Influenza A Human papillomavirus infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Coronavirus disease - COVID-19 Pathways in cancer Autoimmune thyroid disease Lipid and atherosclerosis		Interferon alpha/beta signaling Regulation of IFNA signaling TRAF6 mediated IRF7 activation Factors involved in megakaryocyte development and platelet production

IFNA1 (interferon alpha 1)