ZNF404 (zinc finger protein 404)

Gene

• Entrez ID: 342908
• Gene name: Zinc finger protein 404
• Gene symbol: ZNF404
• Synonyms (NCBI Gene): -
• Chromosome: 19
• Chromosome location: 19q13.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019824	hsa-miR-375	Microarray	20215506
MIRT1523938	hsa-miR-1227	CLIP-seq
MIRT1523939	hsa-miR-455-5p	CLIP-seq
MIRT1523940	hsa-miR-532-5p	CLIP-seq
MIRT2158382	hsa-miR-412	CLIP-seq
MIRT2464242	hsa-miR-3691-3p	CLIP-seq
MIRT2464243	hsa-miR-656	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q494X3
• Protein name: Zinc finger protein 404
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	5 → 46	KRAB box	Family
  PF00096	zf-C2H2	159 → 181	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	187 → 209	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	215 → 237	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	271 → 293	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	299 → 321	Zinc finger, C2H2 type	Domain
  PF13912	zf-C2H2_6	327 → 352		Domain
  PF00096	zf-C2H2	355 → 377	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	383 → 405	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	411 → 433	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	439 → 461	Zinc finger, C2H2 type	Domain
  PF13912	zf-C2H2_6	467 → 492		Domain
  PF00096	zf-C2H2	495 → 517	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	523 → 546	Zinc finger, C2H2 type	Domain

• Sequence:

  MARVPLTFSDVAIDFSQEEWEYLNSDQRDLYRDVMLENYTNLVSLDFNFTTESNKLSSEK
  RNYEVNAYHQETWKRNKTFNLMRFIFRTDPQYTIEFGRQQRPKVGCFSQMIFKKHKSLPL
  HKRNNTREKSYECKEYKKGFRKYLHLTEHLRDHTGVIPYECNECGKAFVVFQHFIRHRKI
  HTDLKPYECNGCEKAFRFYSQLIQHQIIHTGMKPYECKQCGKAFRRHSHLTEHQKIHVGL
  KPFECKECGETFRLYRHMCLHQKIHHGVKPYKCKECGKAFGHRSSLYQHKKIHSGEKPYK
  CEQCEKAFVRSYLLVEHQRSHTGEKPHECMECGKAFGKGSSLLKHKRIHSSEKLYDCKDC
  GKAFCRGSQLTQHQRIHTGEKPHECKECGKTFKLHSYLIQHQIIHTDLKPYECKQCGKAF
  SRVGDLKTHQSIHAGEKPYECKECGKTFRLNSQLIYHQTIHTGLKPYVCKECKKAFRSIS
  GLSQHKRIHTGEKPYECKECDKAFNRSDRLTQHETIHTGVKPQKCKECGKAFSHCYQLSQ
  HQRFHHGERLLM

• Sequence length: 552

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Benign	rs112737770	RCV005913329

Associations from Text Mining
Disease Name	Relationship Type	References
Breast Neoplasms	Associate	28957321