IFI27 (interferon alpha inducible protein 27)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3429
Gene name Gene Name - the full gene name approved by the HGNC.
Interferon alpha inducible protein 27
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
IFI27
Synonyms (NCBI Gene) Gene synonyms aliases
FAM14D, ISG12, ISG12A, P27
Chromosome Chromosome number
14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q32.12
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(21)
miRTarBase ID miRNA Experiments Reference
MIRT021256 hsa-miR-146a-5p Microarray 18057241
MIRT054031 hsa-miR-942-5p Flow, Luciferase reporter assay, qRT-PCR, Western blot 24970806
MIRT054031 hsa-miR-942-5p Flow, Luciferase reporter assay, qRT-PCR, Western blot 24970806
MIRT054031 hsa-miR-942-5p Flow, Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot 24727952
MIRT054031 hsa-miR-942-5p Flow, Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot 24727952
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(25)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IGI 22427340
GO:0001102 Function RNA polymerase II activating transcription factor binding IPI 22427340
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 27194766, 27673746
GO:0005521 Function Lamin binding IDA 22427340
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
600009 5397 ENSG00000165949
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P40305
Protein name Interferon alpha-inducible protein 27, mitochondrial (p27) (Interferon alpha-induced 11.5 kDa protein) (Interferon-stimulated gene 12a protein) (ISG12(a)) (ISG12A)
Protein function Probable adapter protein involved in different biological processes (PubMed:22427340, PubMed:27194766). Part of the signaling pathways that lead to apoptosis (PubMed:18330707, PubMed:24970806, PubMed:27673746). Involved in type-I interferon-indu
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06140 Ifi-6-16 38 → 116 Interferon-induced 6-16 family Family
Sequence
Sequence length 122
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Interferon alpha/beta signaling
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Celiac disease Celiac Disease 30097691 ClinVar
Show/Hide Text Mining Associations (86)
Associations from Text Mining
Disease Name Relationship Type References
Arthritis Psoriatic Stimulate 15086558
Behcet Syndrome Associate 37102643
Breast Neoplasms Associate 11710820, 12878323, 28108626, 33117284
Bronchiolitis Stimulate 17166282
Carcinoma Basal Cell Stimulate 17508019
Carcinoma Hepatocellular Associate 24999841, 30138348, 30821058, 39251909
Carcinoma Pancreatic Ductal Associate 39457004
Carcinoma Renal Cell Associate 26617834
Carcinoma Squamous Cell Associate 34504628
Celiac Disease Associate 30097691