STAC2 (SH3 and cysteine rich domain 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 342667 |
| Gene name | SH3 and cysteine rich domain 2 |
| Gene symbol | STAC2 |
| Synonyms (NCBI Gene) |
24b224b2/STAC2
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| Chromosome | 17 |
| Chromosome location | 17q12 |
| Summary | This gene encodes a protein containing an SH3 domain and a zinc finger domain. The encoded protein has been shown to regulate calcium channel inactivation in a human cell line. Reduced expression of this gene has been observed in human heart failure. [pro |
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SNPs
SNP information provided by dbSNP.
1
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miRNA
miRNA information provided by mirtarbase database.
548
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q6ZMT1 | ||||||||||||||||||||
| Protein name | SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2) | ||||||||||||||||||||
| Protein function | Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C. {ECO:0000250|UniProtKB:Q8 | ||||||||||||||||||||
| PDB | 6B26 , 6B27 , 6B28 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 411 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
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