STAC2 (SH3 and cysteine rich domain 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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342667 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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SH3 and cysteine rich domain 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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STAC2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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24b2, 24b2/STAC2 |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q12 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein containing an SH3 domain and a zinc finger domain. The encoded protein has been shown to regulate calcium channel inactivation in a human cell line. Reduced expression of this gene has been observed in human heart failure. [pro |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q6ZMT1 | ||||||||||||||||||||
Protein name | SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2) | ||||||||||||||||||||
Protein function | Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C. {ECO:0000250|UniProtKB:Q8 | ||||||||||||||||||||
PDB | 6B26 , 6B27 , 6B28 | ||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 411 | ||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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