Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	341676
Gene name	NIMA related kinase 5
Gene symbol	NEK5
Synonyms (NCBI Gene)	-
Chromosome	13
Chromosome location	13q14.3

208

Show/Hide all (208)

miRTarBase ID	miRNA	Experiments
MIRT1180185	hsa-miR-103a	CLIP-seq
MIRT1180186	hsa-miR-107	CLIP-seq
MIRT1180187	hsa-miR-10a	CLIP-seq
MIRT1180188	hsa-miR-10b	CLIP-seq
MIRT1180189	hsa-miR-1273e	CLIP-seq
MIRT1180190	hsa-miR-1297	CLIP-seq
MIRT1180191	hsa-miR-130a	CLIP-seq
MIRT1180192	hsa-miR-130b	CLIP-seq
MIRT1180193	hsa-miR-141	CLIP-seq
MIRT1180194	hsa-miR-143	CLIP-seq
MIRT1180195	hsa-miR-1470	CLIP-seq
MIRT1180196	hsa-miR-148a	CLIP-seq
MIRT1180197	hsa-miR-148b	CLIP-seq
MIRT1180198	hsa-miR-152	CLIP-seq
MIRT1180199	hsa-miR-1912	CLIP-seq
MIRT1180200	hsa-miR-1914	CLIP-seq
MIRT1180201	hsa-miR-1915	CLIP-seq
MIRT1180202	hsa-miR-197	CLIP-seq
MIRT1180203	hsa-miR-200a	CLIP-seq
MIRT1180204	hsa-miR-2053	CLIP-seq
MIRT1180205	hsa-miR-216a	CLIP-seq
MIRT1180206	hsa-miR-216b	CLIP-seq
MIRT1180207	hsa-miR-218	CLIP-seq
MIRT1180208	hsa-miR-26a	CLIP-seq
MIRT1180209	hsa-miR-26b	CLIP-seq
MIRT1180210	hsa-miR-301a	CLIP-seq
MIRT1180211	hsa-miR-301b	CLIP-seq
MIRT1180212	hsa-miR-3130-5p	CLIP-seq
MIRT1180213	hsa-miR-34a	CLIP-seq
MIRT1180214	hsa-miR-34c-5p	CLIP-seq
MIRT1180215	hsa-miR-3610	CLIP-seq
MIRT1180216	hsa-miR-3614-5p	CLIP-seq
MIRT1180217	hsa-miR-3657	CLIP-seq
MIRT1180218	hsa-miR-3666	CLIP-seq
MIRT1180219	hsa-miR-3714	CLIP-seq
MIRT1180220	hsa-miR-375	CLIP-seq
MIRT1180221	hsa-miR-3919	CLIP-seq
MIRT1180222	hsa-miR-3921	CLIP-seq
MIRT1180223	hsa-miR-4295	CLIP-seq
MIRT1180224	hsa-miR-4436b-3p	CLIP-seq
MIRT1180225	hsa-miR-4465	CLIP-seq
MIRT1180226	hsa-miR-4482	CLIP-seq
MIRT1180227	hsa-miR-4493	CLIP-seq
MIRT1180228	hsa-miR-449a	CLIP-seq
MIRT1180229	hsa-miR-449b	CLIP-seq
MIRT1180230	hsa-miR-454	CLIP-seq
MIRT1180231	hsa-miR-4635	CLIP-seq
MIRT1180232	hsa-miR-4640-3p	CLIP-seq
MIRT1180233	hsa-miR-4653-5p	CLIP-seq
MIRT1180234	hsa-miR-4667-3p	CLIP-seq
MIRT1180235	hsa-miR-4669	CLIP-seq
MIRT1180236	hsa-miR-4686	CLIP-seq
MIRT1180237	hsa-miR-4696	CLIP-seq
MIRT1180238	hsa-miR-4717-5p	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT1180240	hsa-miR-4753-5p	CLIP-seq
MIRT1180241	hsa-miR-4756-3p	CLIP-seq
MIRT1180242	hsa-miR-4766-5p	CLIP-seq
MIRT1180243	hsa-miR-4770	CLIP-seq
MIRT1180244	hsa-miR-4790-3p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT1180246	hsa-miR-513c	CLIP-seq
MIRT1180247	hsa-miR-514b-5p	CLIP-seq
MIRT1180248	hsa-miR-576-3p	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180250	hsa-miR-628-5p	CLIP-seq
MIRT1180251	hsa-miR-636	CLIP-seq
MIRT1180252	hsa-miR-642a	CLIP-seq
MIRT1180185	hsa-miR-103a	CLIP-seq
MIRT1180186	hsa-miR-107	CLIP-seq
MIRT1180195	hsa-miR-1470	CLIP-seq
MIRT2052134	hsa-miR-2355-3p	CLIP-seq
MIRT1180216	hsa-miR-3614-5p	CLIP-seq
MIRT2052135	hsa-miR-3653	CLIP-seq
MIRT2052136	hsa-miR-3658	CLIP-seq
MIRT1180219	hsa-miR-3714	CLIP-seq
MIRT1180220	hsa-miR-375	CLIP-seq
MIRT1180227	hsa-miR-4493	CLIP-seq
MIRT1180231	hsa-miR-4635	CLIP-seq
MIRT1180234	hsa-miR-4667-3p	CLIP-seq
MIRT1180236	hsa-miR-4686	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT2052137	hsa-miR-4725-5p	CLIP-seq
MIRT1180244	hsa-miR-4790-3p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT2052138	hsa-miR-504	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180250	hsa-miR-628-5p	CLIP-seq
MIRT1180252	hsa-miR-642a	CLIP-seq
MIRT2052139	hsa-miR-676	CLIP-seq
MIRT1180185	hsa-miR-103a	CLIP-seq
MIRT1180186	hsa-miR-107	CLIP-seq
MIRT1180187	hsa-miR-10a	CLIP-seq
MIRT1180188	hsa-miR-10b	CLIP-seq
MIRT1180189	hsa-miR-1273e	CLIP-seq
MIRT1180190	hsa-miR-1297	CLIP-seq
MIRT1180193	hsa-miR-141	CLIP-seq
MIRT1180195	hsa-miR-1470	CLIP-seq
MIRT1180199	hsa-miR-1912	CLIP-seq
MIRT1180200	hsa-miR-1914	CLIP-seq
MIRT1180201	hsa-miR-1915	CLIP-seq
MIRT1180202	hsa-miR-197	CLIP-seq
MIRT1180203	hsa-miR-200a	CLIP-seq
MIRT1180204	hsa-miR-2053	CLIP-seq
MIRT1180205	hsa-miR-216a	CLIP-seq
MIRT1180206	hsa-miR-216b	CLIP-seq
MIRT1180207	hsa-miR-218	CLIP-seq
MIRT2052134	hsa-miR-2355-3p	CLIP-seq
MIRT1180208	hsa-miR-26a	CLIP-seq
MIRT1180209	hsa-miR-26b	CLIP-seq
MIRT1180212	hsa-miR-3130-5p	CLIP-seq
MIRT2281443	hsa-miR-3135	CLIP-seq
MIRT2281444	hsa-miR-3182	CLIP-seq
MIRT2281445	hsa-miR-3189-3p	CLIP-seq
MIRT1180216	hsa-miR-3614-5p	CLIP-seq
MIRT2052135	hsa-miR-3653	CLIP-seq
MIRT1180217	hsa-miR-3657	CLIP-seq
MIRT2052136	hsa-miR-3658	CLIP-seq
MIRT1180219	hsa-miR-3714	CLIP-seq
MIRT1180220	hsa-miR-375	CLIP-seq
MIRT2281446	hsa-miR-3909	CLIP-seq
MIRT1180221	hsa-miR-3919	CLIP-seq
MIRT1180222	hsa-miR-3921	CLIP-seq
MIRT2281447	hsa-miR-4312	CLIP-seq
MIRT1180225	hsa-miR-4465	CLIP-seq
MIRT1180226	hsa-miR-4482	CLIP-seq
MIRT1180227	hsa-miR-4493	CLIP-seq
MIRT2281448	hsa-miR-450b-3p	CLIP-seq
MIRT1180231	hsa-miR-4635	CLIP-seq
MIRT1180232	hsa-miR-4640-3p	CLIP-seq
MIRT1180233	hsa-miR-4653-5p	CLIP-seq
MIRT2281449	hsa-miR-4659a-3p	CLIP-seq
MIRT2281450	hsa-miR-4659b-3p	CLIP-seq
MIRT1180234	hsa-miR-4667-3p	CLIP-seq
MIRT1180235	hsa-miR-4669	CLIP-seq
MIRT1180236	hsa-miR-4686	CLIP-seq
MIRT2281451	hsa-miR-4713-3p	CLIP-seq
MIRT1180238	hsa-miR-4717-5p	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT2052137	hsa-miR-4725-5p	CLIP-seq
MIRT2281452	hsa-miR-4727-5p	CLIP-seq
MIRT1180240	hsa-miR-4753-5p	CLIP-seq
MIRT1180241	hsa-miR-4756-3p	CLIP-seq
MIRT1180242	hsa-miR-4766-5p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT2052138	hsa-miR-504	CLIP-seq
MIRT1180246	hsa-miR-513c	CLIP-seq
MIRT1180247	hsa-miR-514b-5p	CLIP-seq
MIRT1180248	hsa-miR-576-3p	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180250	hsa-miR-628-5p	CLIP-seq
MIRT1180251	hsa-miR-636	CLIP-seq
MIRT2281453	hsa-miR-638	CLIP-seq
MIRT1180252	hsa-miR-642a	CLIP-seq
MIRT2052139	hsa-miR-676	CLIP-seq
MIRT2281454	hsa-miR-769-3p	CLIP-seq
MIRT1180195	hsa-miR-1470	CLIP-seq
MIRT2052134	hsa-miR-2355-3p	CLIP-seq
MIRT1180217	hsa-miR-3657	CLIP-seq
MIRT1180221	hsa-miR-3919	CLIP-seq
MIRT1180234	hsa-miR-4667-3p	CLIP-seq
MIRT1180235	hsa-miR-4669	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT2052137	hsa-miR-4725-5p	CLIP-seq
MIRT1180241	hsa-miR-4756-3p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT2052138	hsa-miR-504	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180252	hsa-miR-642a	CLIP-seq
MIRT2052139	hsa-miR-676	CLIP-seq
MIRT1180217	hsa-miR-3657	CLIP-seq
MIRT1180235	hsa-miR-4669	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT2052137	hsa-miR-4725-5p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT2052138	hsa-miR-504	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180195	hsa-miR-1470	CLIP-seq
MIRT2052134	hsa-miR-2355-3p	CLIP-seq
MIRT1180216	hsa-miR-3614-5p	CLIP-seq
MIRT1180217	hsa-miR-3657	CLIP-seq
MIRT1180220	hsa-miR-375	CLIP-seq
MIRT1180221	hsa-miR-3919	CLIP-seq
MIRT1180234	hsa-miR-4667-3p	CLIP-seq
MIRT1180235	hsa-miR-4669	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT2052137	hsa-miR-4725-5p	CLIP-seq
MIRT1180241	hsa-miR-4756-3p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT2052138	hsa-miR-504	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180252	hsa-miR-642a	CLIP-seq
MIRT2052139	hsa-miR-676	CLIP-seq
MIRT2579801	hsa-miR-769-5p	CLIP-seq
MIRT1180195	hsa-miR-1470	CLIP-seq
MIRT2052134	hsa-miR-2355-3p	CLIP-seq
MIRT1180217	hsa-miR-3657	CLIP-seq
MIRT1180221	hsa-miR-3919	CLIP-seq
MIRT1180234	hsa-miR-4667-3p	CLIP-seq
MIRT1180235	hsa-miR-4669	CLIP-seq
MIRT1180239	hsa-miR-4722-3p	CLIP-seq
MIRT2052137	hsa-miR-4725-5p	CLIP-seq
MIRT1180241	hsa-miR-4756-3p	CLIP-seq
MIRT1180245	hsa-miR-494	CLIP-seq
MIRT2052138	hsa-miR-504	CLIP-seq
MIRT1180249	hsa-miR-605	CLIP-seq
MIRT1180252	hsa-miR-642a	CLIP-seq
MIRT2052139	hsa-miR-676	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IBA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005929	Component	Cilium	IDA	31429579
GO:0005929	Component	Cilium	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0031514	Component	Motile cilium	IEA
GO:0036126	Component	Sperm flagellum	IDA	31429579
GO:0042995	Component	Cell projection	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0106310	Function	Protein serine kinase activity	IEA

MIM	HGNC	e!Ensembl
616731	7748	ENSG00000197168

Q6P3R8

Protein name

Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	4 → 259	Protein kinase domain	Domain

Sequence

MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKH
PNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIH
DRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKP
YNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLF
QVSPRDRPSINSILKRPFLENLIPKYLTPEVIQEEFSHMLICRAGAPASRHAGKVVQKCK
IQKVRFQGKCPPRSRISVPIKRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDY
YYAQLDMLRRRAHKPSYHPIPQENTGVEDYGQETRHGPSPSQWPAEYLQRKFEAQQYKLK
VEKQLGLRPSSAEPNYNQRQELRSNGEEPRFQELPFRKNEMKEQEYWKQLEEIRQQYHND
MKEIRKKMGREPEENSKISHKTYLVKKSNLPVHQDASEGEAPVQMEFRSCCPGWSAMARS
WLTATSASQDIEKDLKQMRLQNTKESKNPEQKYKAKKGVKFEINLDKCISDENILQEEEA
MDIPNETLTFEDGMKFKEYECVKEHGDYTDKAFEKLHCPEAGFSTQTVAAVGNRRQWDGG
APQTLLQMMAVADITSTCPTGPDSESVLSVSRQEGKTKDPYSPVLILM

Sequence length

708

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CROHN'S DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Associate	36550548	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	31906878, 36550548	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Hyperplasia	Associate	28380430	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	28380430	★★★★★ ★☆☆☆☆ Found in Text Mining only

NEK5 (NIMA related kinase 5)