Gene Gene information from NCBI Gene database.
Entrez ID 341116
Gene name Membrane spanning 4-domains A10
Gene symbol MS4A10
Synonyms (NCBI Gene)
CD20L7MS4A9
Chromosome 11
Chromosome location 11q12.2
Summary Most MS4A genes, including MS4A10, encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons.[supplied by OMIM, Apr 2004]
miRNA miRNA information provided by mirtarbase database.
449
miRTarBase ID miRNA Experiments Reference
MIRT051606 hsa-let-7e-5p CLASH 23622248
MIRT1160825 hsa-miR-10a CLIP-seq
MIRT1160826 hsa-miR-10b CLIP-seq
MIRT1160827 hsa-miR-1262 CLIP-seq
MIRT1160828 hsa-miR-1268 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 33961781, 35044719
GO:0005886 Component Plasma membrane IBA
GO:0007166 Process Cell surface receptor signaling pathway IBA
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608403 13368 ENSG00000172689
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96PG2
Protein name Membrane-spanning 4-domains subfamily A member 10 (CD20 antigen-like 7)
Protein function May be involved in signal transduction as a component of a multimeric receptor complex.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04103 CD20 59 193 CD20-like family Family
Sequence
MKAEATVIPSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQKKSSLLKEL
GAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYL
KMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVL
ELFLPVPTAVTAW
RGDCPSAKNDDACLVPNTPLHLKGLPVEPPPSYQSVIQGDAQHKQHQ
RLREVKQVAPDTWIVTDGAAIWTQTAN
Sequence length 267
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
GRANULOMATOSIS WITH POLYANGIITIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations