NANOS1 (nanos C2HC-type zinc finger 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 340719 |
| Gene name | Nanos C2HC-type zinc finger 1 |
| Gene symbol | NANOS1 |
| Synonyms (NCBI Gene) |
EC_Rep1aNOS-1NOS1SPGF12ZC2HC12A
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| Chromosome | 10 |
| Chromosome location | 10q26.11 |
| Summary | This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repr |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
478
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8WY41 | ||||||||||
| Protein name | Nanos homolog 1 (NOS-1) (EC_Rep1a) | ||||||||||
| Protein function | May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadhe | ||||||||||
| PDB | 4CQO | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Testis and ovary (at protein level). Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed durin | ||||||||||
| Sequence |
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| Sequence length | 292 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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