ANKRD45 (ankyrin repeat domain 45)

Gene

• Entrez ID: 339416
• Gene name: Ankyrin repeat domain 45
• Gene symbol: ANKRD45
• Synonyms (NCBI Gene): CT117
• Chromosome: 1
• Chromosome location: 1q25.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT647190	hsa-miR-6757-3p	HITS-CLIP	23824327
MIRT647189	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT647188	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT647187	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT647186	hsa-miR-4299	HITS-CLIP	23824327
MIRT647185	hsa-miR-548q	HITS-CLIP	23824327
MIRT647184	hsa-miR-4456	HITS-CLIP	23824327
MIRT647183	hsa-miR-7978	HITS-CLIP	23824327
MIRT647182	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT647181	hsa-miR-623	HITS-CLIP	23824327
MIRT647180	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT647179	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT647178	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT647177	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT489178	hsa-miR-1321	PAR-CLIP	23446348
MIRT489177	hsa-miR-4739	PAR-CLIP	23446348
MIRT489176	hsa-miR-4756-5p	PAR-CLIP	23446348
MIRT513066	hsa-miR-6783-5p	PAR-CLIP	23446348
MIRT489175	hsa-miR-7515	PAR-CLIP	23446348
MIRT489174	hsa-miR-3202	PAR-CLIP	23446348
MIRT513065	hsa-miR-4747-5p	PAR-CLIP	23446348
MIRT513064	hsa-miR-5196-5p	PAR-CLIP	23446348
MIRT489171	hsa-miR-149-3p	PAR-CLIP	23446348
MIRT489170	hsa-miR-4728-5p	PAR-CLIP	23446348
MIRT489169	hsa-miR-6785-5p	PAR-CLIP	23446348
MIRT489168	hsa-miR-6883-5p	PAR-CLIP	23446348
MIRT513063	hsa-miR-4271	PAR-CLIP	23446348
MIRT513062	hsa-miR-4725-3p	PAR-CLIP	23446348
MIRT513060	hsa-miR-6780b-5p	PAR-CLIP	23446348
MIRT499607	hsa-miR-4787-5p	PAR-CLIP	24398324
MIRT499606	hsa-miR-4706	PAR-CLIP	24398324
MIRT499605	hsa-miR-4749-5p	PAR-CLIP	24398324
MIRT499604	hsa-miR-744-5p	PAR-CLIP	24398324
MIRT499603	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT499602	hsa-miR-4306	PAR-CLIP	24398324
MIRT499600	hsa-miR-4644	PAR-CLIP	24398324
MIRT499601	hsa-miR-5192	PAR-CLIP	24398324
MIRT499599	hsa-miR-6752-5p	PAR-CLIP	24398324
MIRT499598	hsa-miR-6842-5p	PAR-CLIP	24398324
MIRT499597	hsa-miR-7110-5p	PAR-CLIP	24398324
MIRT499596	hsa-miR-4651	PAR-CLIP	24398324
MIRT499595	hsa-miR-608	PAR-CLIP	24398324
MIRT499594	hsa-miR-363-5p	PAR-CLIP	24398324
MIRT499593	hsa-miR-6745	PAR-CLIP	24398324
MIRT499592	hsa-miR-6880-5p	PAR-CLIP	24398324
MIRT489184	hsa-miR-3125	PAR-CLIP	23592263
MIRT489183	hsa-miR-3916	PAR-CLIP	23592263
MIRT489182	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT489181	hsa-miR-4476	PAR-CLIP	23592263
MIRT489180	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT489179	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT489178	hsa-miR-1321	PAR-CLIP	23592263
MIRT489177	hsa-miR-4739	PAR-CLIP	23592263
MIRT489176	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT489175	hsa-miR-7515	PAR-CLIP	23592263
MIRT489174	hsa-miR-3202	PAR-CLIP	23592263
MIRT489173	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT489172	hsa-miR-8085	PAR-CLIP	23592263
MIRT489171	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT489170	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT489169	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT489168	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT489167	hsa-miR-3175	PAR-CLIP	23592263
MIRT489166	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT647190	hsa-miR-6757-3p	HITS-CLIP	23824327
MIRT647189	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT647188	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT647187	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT647186	hsa-miR-4299	HITS-CLIP	23824327
MIRT647185	hsa-miR-548q	HITS-CLIP	23824327
MIRT647184	hsa-miR-4456	HITS-CLIP	23824327
MIRT647183	hsa-miR-7978	HITS-CLIP	23824327
MIRT647182	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT647181	hsa-miR-623	HITS-CLIP	23824327
MIRT647180	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT647179	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT647178	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT647177	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT489178	hsa-miR-1321	PAR-CLIP	23446348
MIRT489177	hsa-miR-4739	PAR-CLIP	23446348
MIRT489176	hsa-miR-4756-5p	PAR-CLIP	23446348
MIRT513066	hsa-miR-6783-5p	PAR-CLIP	23446348
MIRT489175	hsa-miR-7515	PAR-CLIP	23446348
MIRT489174	hsa-miR-3202	PAR-CLIP	23446348
MIRT513065	hsa-miR-4747-5p	PAR-CLIP	23446348
MIRT513064	hsa-miR-5196-5p	PAR-CLIP	23446348
MIRT489171	hsa-miR-149-3p	PAR-CLIP	23446348
MIRT489170	hsa-miR-4728-5p	PAR-CLIP	23446348
MIRT489169	hsa-miR-6785-5p	PAR-CLIP	23446348
MIRT489168	hsa-miR-6883-5p	PAR-CLIP	23446348
MIRT513063	hsa-miR-4271	PAR-CLIP	23446348
MIRT513062	hsa-miR-4725-3p	PAR-CLIP	23446348
MIRT513060	hsa-miR-6780b-5p	PAR-CLIP	23446348
MIRT499607	hsa-miR-4787-5p	PAR-CLIP	24398324
MIRT499606	hsa-miR-4706	PAR-CLIP	24398324
MIRT499605	hsa-miR-4749-5p	PAR-CLIP	24398324
MIRT499604	hsa-miR-744-5p	PAR-CLIP	24398324
MIRT499603	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT499602	hsa-miR-4306	PAR-CLIP	24398324
MIRT499600	hsa-miR-4644	PAR-CLIP	24398324
MIRT499601	hsa-miR-5192	PAR-CLIP	24398324
MIRT499599	hsa-miR-6752-5p	PAR-CLIP	24398324
MIRT499598	hsa-miR-6842-5p	PAR-CLIP	24398324
MIRT499597	hsa-miR-7110-5p	PAR-CLIP	24398324
MIRT499596	hsa-miR-4651	PAR-CLIP	24398324
MIRT499595	hsa-miR-608	PAR-CLIP	24398324
MIRT499594	hsa-miR-363-5p	PAR-CLIP	24398324
MIRT499593	hsa-miR-6745	PAR-CLIP	24398324
MIRT499592	hsa-miR-6880-5p	PAR-CLIP	24398324
MIRT489184	hsa-miR-3125	PAR-CLIP	23592263
MIRT489183	hsa-miR-3916	PAR-CLIP	23592263
MIRT489182	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT489181	hsa-miR-4476	PAR-CLIP	23592263
MIRT489180	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT489179	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT489178	hsa-miR-1321	PAR-CLIP	23592263
MIRT489177	hsa-miR-4739	PAR-CLIP	23592263
MIRT489176	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT489175	hsa-miR-7515	PAR-CLIP	23592263
MIRT489174	hsa-miR-3202	PAR-CLIP	23592263
MIRT489173	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT489172	hsa-miR-8085	PAR-CLIP	23592263
MIRT489171	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT489170	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT489169	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT489168	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT489167	hsa-miR-3175	PAR-CLIP	23592263
MIRT489166	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT784159	hsa-miR-1	CLIP-seq
MIRT784160	hsa-miR-10a	CLIP-seq
MIRT784161	hsa-miR-10b	CLIP-seq
MIRT784162	hsa-miR-197	CLIP-seq
MIRT784163	hsa-miR-206	CLIP-seq
MIRT784164	hsa-miR-3149	CLIP-seq
MIRT784165	hsa-miR-3185	CLIP-seq
MIRT784166	hsa-miR-3187-3p	CLIP-seq
MIRT784167	hsa-miR-339-5p	CLIP-seq
MIRT784168	hsa-miR-3614-5p	CLIP-seq
MIRT784169	hsa-miR-3652	CLIP-seq
MIRT784170	hsa-miR-3664-5p	CLIP-seq
MIRT784171	hsa-miR-3673	CLIP-seq
MIRT784172	hsa-miR-3689a-3p	CLIP-seq
MIRT784173	hsa-miR-3689c	CLIP-seq
MIRT784174	hsa-miR-411	CLIP-seq
MIRT784175	hsa-miR-4430	CLIP-seq
MIRT784176	hsa-miR-4435	CLIP-seq
MIRT784177	hsa-miR-4466	CLIP-seq
MIRT784178	hsa-miR-4639-3p	CLIP-seq
MIRT784179	hsa-miR-4658	CLIP-seq
MIRT784180	hsa-miR-4701-5p	CLIP-seq
MIRT784181	hsa-miR-4716-5p	CLIP-seq
MIRT784182	hsa-miR-4725-5p	CLIP-seq
MIRT784183	hsa-miR-4755-3p	CLIP-seq
MIRT784184	hsa-miR-4758-5p	CLIP-seq
MIRT784185	hsa-miR-4781-3p	CLIP-seq
MIRT784186	hsa-miR-504	CLIP-seq
MIRT784187	hsa-miR-5096	CLIP-seq
MIRT784188	hsa-miR-541	CLIP-seq
MIRT784189	hsa-miR-548s	CLIP-seq
MIRT784190	hsa-miR-571	CLIP-seq
MIRT784191	hsa-miR-588	CLIP-seq
MIRT784192	hsa-miR-613	CLIP-seq
MIRT784193	hsa-miR-654-5p	CLIP-seq
MIRT784194	hsa-miR-675	CLIP-seq
MIRT784166	hsa-miR-3187-3p	CLIP-seq
MIRT784176	hsa-miR-4435	CLIP-seq
MIRT784180	hsa-miR-4701-5p	CLIP-seq
MIRT784181	hsa-miR-4716-5p	CLIP-seq
MIRT784183	hsa-miR-4755-3p	CLIP-seq
MIRT784185	hsa-miR-4781-3p	CLIP-seq
MIRT784189	hsa-miR-548s	CLIP-seq
MIRT784191	hsa-miR-588	CLIP-seq
MIRT1555948	hsa-miR-185	CLIP-seq
MIRT1555949	hsa-miR-744	CLIP-seq
MIRT784159	hsa-miR-1	CLIP-seq
MIRT1555948	hsa-miR-185	CLIP-seq
MIRT784163	hsa-miR-206	CLIP-seq
MIRT1931288	hsa-miR-3163	CLIP-seq
MIRT784169	hsa-miR-3652	CLIP-seq
MIRT784170	hsa-miR-3664-5p	CLIP-seq
MIRT784171	hsa-miR-3673	CLIP-seq
MIRT1931289	hsa-miR-4263	CLIP-seq
MIRT784175	hsa-miR-4430	CLIP-seq
MIRT784177	hsa-miR-4466	CLIP-seq
MIRT784178	hsa-miR-4639-3p	CLIP-seq
MIRT1931290	hsa-miR-548a-3p	CLIP-seq
MIRT1931291	hsa-miR-548e	CLIP-seq
MIRT1931292	hsa-miR-548f	CLIP-seq
MIRT1931293	hsa-miR-552	CLIP-seq
MIRT784192	hsa-miR-613	CLIP-seq
MIRT784194	hsa-miR-675	CLIP-seq
MIRT1555949	hsa-miR-744	CLIP-seq
MIRT784159	hsa-miR-1	CLIP-seq
MIRT2171863	hsa-miR-125a-3p	CLIP-seq
MIRT2171864	hsa-miR-1285	CLIP-seq
MIRT2171865	hsa-miR-1289	CLIP-seq
MIRT2171866	hsa-miR-1307	CLIP-seq
MIRT2171867	hsa-miR-150	CLIP-seq
MIRT1555948	hsa-miR-185	CLIP-seq
MIRT784162	hsa-miR-197	CLIP-seq
MIRT784163	hsa-miR-206	CLIP-seq
MIRT2171868	hsa-miR-217	CLIP-seq
MIRT2171869	hsa-miR-24	CLIP-seq
MIRT784166	hsa-miR-3187-3p	CLIP-seq
MIRT2171870	hsa-miR-3187-5p	CLIP-seq
MIRT2171871	hsa-miR-3198	CLIP-seq
MIRT2171872	hsa-miR-3613-5p	CLIP-seq
MIRT784169	hsa-miR-3652	CLIP-seq
MIRT784170	hsa-miR-3664-5p	CLIP-seq
MIRT784171	hsa-miR-3673	CLIP-seq
MIRT2171873	hsa-miR-380	CLIP-seq
MIRT2171874	hsa-miR-3934	CLIP-seq
MIRT2171875	hsa-miR-409-3p	CLIP-seq
MIRT784174	hsa-miR-411	CLIP-seq
MIRT2171876	hsa-miR-4294	CLIP-seq
MIRT2171877	hsa-miR-4309	CLIP-seq
MIRT2171878	hsa-miR-4312	CLIP-seq
MIRT2171879	hsa-miR-432	CLIP-seq
MIRT784175	hsa-miR-4430	CLIP-seq
MIRT784176	hsa-miR-4435	CLIP-seq
MIRT2171880	hsa-miR-4437	CLIP-seq
MIRT2171881	hsa-miR-4454	CLIP-seq
MIRT784177	hsa-miR-4466	CLIP-seq
MIRT2171882	hsa-miR-4532	CLIP-seq
MIRT2171883	hsa-miR-4638-5p	CLIP-seq
MIRT784178	hsa-miR-4639-3p	CLIP-seq
MIRT784180	hsa-miR-4701-5p	CLIP-seq
MIRT784181	hsa-miR-4716-5p	CLIP-seq
MIRT2171884	hsa-miR-4722-5p	CLIP-seq
MIRT784183	hsa-miR-4755-3p	CLIP-seq
MIRT2171885	hsa-miR-4757-5p	CLIP-seq
MIRT2171886	hsa-miR-4763-5p	CLIP-seq
MIRT2171887	hsa-miR-4764-3p	CLIP-seq
MIRT2171888	hsa-miR-4768-3p	CLIP-seq
MIRT784185	hsa-miR-4781-3p	CLIP-seq
MIRT2171889	hsa-miR-5095	CLIP-seq
MIRT784187	hsa-miR-5096	CLIP-seq
MIRT784189	hsa-miR-548s	CLIP-seq
MIRT1931293	hsa-miR-552	CLIP-seq
MIRT2171890	hsa-miR-582-5p	CLIP-seq
MIRT784191	hsa-miR-588	CLIP-seq
MIRT2171891	hsa-miR-610	CLIP-seq
MIRT2171892	hsa-miR-612	CLIP-seq
MIRT784192	hsa-miR-613	CLIP-seq
MIRT2171893	hsa-miR-661	CLIP-seq
MIRT784194	hsa-miR-675	CLIP-seq
MIRT2171894	hsa-miR-764	CLIP-seq
MIRT784159	hsa-miR-1	CLIP-seq
MIRT2171866	hsa-miR-1307	CLIP-seq
MIRT784163	hsa-miR-206	CLIP-seq
MIRT784169	hsa-miR-3652	CLIP-seq
MIRT784170	hsa-miR-3664-5p	CLIP-seq
MIRT784171	hsa-miR-3673	CLIP-seq
MIRT2384224	hsa-miR-4284	CLIP-seq
MIRT2171879	hsa-miR-432	CLIP-seq
MIRT784175	hsa-miR-4430	CLIP-seq
MIRT784177	hsa-miR-4466	CLIP-seq
MIRT2171883	hsa-miR-4638-5p	CLIP-seq
MIRT784178	hsa-miR-4639-3p	CLIP-seq
MIRT2384225	hsa-miR-4772-3p	CLIP-seq
MIRT2171889	hsa-miR-5095	CLIP-seq
MIRT1931293	hsa-miR-552	CLIP-seq
MIRT784192	hsa-miR-613	CLIP-seq
MIRT784194	hsa-miR-675	CLIP-seq
MIRT2443699	hsa-miR-663b	CLIP-seq
MIRT784159	hsa-miR-1	CLIP-seq
MIRT2171863	hsa-miR-125a-3p	CLIP-seq
MIRT2171866	hsa-miR-1307	CLIP-seq
MIRT784163	hsa-miR-206	CLIP-seq
MIRT2171869	hsa-miR-24	CLIP-seq
MIRT784169	hsa-miR-3652	CLIP-seq
MIRT784171	hsa-miR-3673	CLIP-seq
MIRT2171874	hsa-miR-3934	CLIP-seq
MIRT2384224	hsa-miR-4284	CLIP-seq
MIRT784175	hsa-miR-4430	CLIP-seq
MIRT2171880	hsa-miR-4437	CLIP-seq
MIRT784177	hsa-miR-4466	CLIP-seq
MIRT2171882	hsa-miR-4532	CLIP-seq
MIRT2171883	hsa-miR-4638-5p	CLIP-seq
MIRT784192	hsa-miR-613	CLIP-seq
MIRT784194	hsa-miR-675	CLIP-seq
MIRT2171894	hsa-miR-764	CLIP-seq
MIRT784159	hsa-miR-1	CLIP-seq
MIRT2171863	hsa-miR-125a-3p	CLIP-seq
MIRT2171866	hsa-miR-1307	CLIP-seq
MIRT784163	hsa-miR-206	CLIP-seq
MIRT2171869	hsa-miR-24	CLIP-seq
MIRT784169	hsa-miR-3652	CLIP-seq
MIRT784171	hsa-miR-3673	CLIP-seq
MIRT2171874	hsa-miR-3934	CLIP-seq
MIRT2384224	hsa-miR-4284	CLIP-seq
MIRT784175	hsa-miR-4430	CLIP-seq
MIRT2171880	hsa-miR-4437	CLIP-seq
MIRT784177	hsa-miR-4466	CLIP-seq
MIRT2171882	hsa-miR-4532	CLIP-seq
MIRT2171883	hsa-miR-4638-5p	CLIP-seq
MIRT2384225	hsa-miR-4772-3p	CLIP-seq
MIRT784192	hsa-miR-613	CLIP-seq
MIRT784194	hsa-miR-675	CLIP-seq
MIRT2171894	hsa-miR-764	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005737	Component	Cytoplasm	IDA	31208154
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0008283	Process	Cell population proliferation	IMP	31208154
GO:0030496	Component	Midbody	IDA	31208154
GO:0032154	Component	Cleavage furrow	IDA	31208154
GO:0032154	Component	Cleavage furrow	IEA
GO:0090543	Component	Flemming body	IEA

Other IDs

• MIM: 618712
• HGNC: 24786
• e!Ensembl: ENSG00000183831

Protein

• UniProt ID: Q5TZF3
• Protein name: Ankyrin repeat domain-containing protein 45
• Protein function: May play a role during cell division.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	57 → 140	Ankyrin repeats (3 copies)	Repeat

• Sequence:

  MESEGPPESESSEFFSQQEEENEEEEAQEPEETGPKNPLLQPALTGDVEGLQKIFEDPEN
  PHHEQAMQLLLEEDIVGRNLLYAACMAGQSDVIRALAKYGVNLNEKTTRGYTLLHCAAAW
  GRLETLKALVELDVDIEALNFREERARDVAARYSQTECVEFLDWADARLTLKKYIAKVSL
  AVTDTEKGSGKLLKEDKNTILSACRAKNEWLETHTEASINELFEQRQQLEDIVTPIFTKM
  TTPCQVKSAKSVTSHDQKRSQDDTSN

• Sequence length: 266

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
IDIOPATHIC OSTEONECROSIS OF THE FEMORAL HEAD	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSYCHIATRIC DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Carcinoma Hepatocellular	Associate	28418032	★☆☆☆☆ Found in Text Mining only