Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	339344
Gene name	Myb related transcription factor, partner of profilin
Gene symbol	MYPOP
Synonyms (NCBI Gene)	P42pop
Chromosome	19
Chromosome location	19q13.32

205

Show/Hide all (205)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038718	hsa-miR-93-3p	CLASH	23622248
MIRT440160	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT440160	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT1170445	hsa-miR-1207-3p	CLIP-seq
MIRT1170446	hsa-miR-1236	CLIP-seq
MIRT1170447	hsa-miR-1258	CLIP-seq
MIRT1170448	hsa-miR-1289	CLIP-seq
MIRT1170449	hsa-miR-1297	CLIP-seq
MIRT1170450	hsa-miR-1301	CLIP-seq
MIRT1170451	hsa-miR-1321	CLIP-seq
MIRT1170452	hsa-miR-1324	CLIP-seq
MIRT1170453	hsa-miR-135a	CLIP-seq
MIRT1170454	hsa-miR-135b	CLIP-seq
MIRT1170455	hsa-miR-1827	CLIP-seq
MIRT1170456	hsa-miR-2110	CLIP-seq
MIRT1170457	hsa-miR-26a	CLIP-seq
MIRT1170458	hsa-miR-26b	CLIP-seq
MIRT1170459	hsa-miR-3150a-3p	CLIP-seq
MIRT1170460	hsa-miR-3162-5p	CLIP-seq
MIRT1170461	hsa-miR-3166	CLIP-seq
MIRT1170462	hsa-miR-3175	CLIP-seq
MIRT1170463	hsa-miR-3179	CLIP-seq
MIRT1170464	hsa-miR-3202	CLIP-seq
MIRT1170465	hsa-miR-3612	CLIP-seq
MIRT1170466	hsa-miR-361-3p	CLIP-seq
MIRT1170467	hsa-miR-3689d	CLIP-seq
MIRT1170468	hsa-miR-3919	CLIP-seq
MIRT1170469	hsa-miR-3936	CLIP-seq
MIRT1170470	hsa-miR-3944-5p	CLIP-seq
MIRT1170471	hsa-miR-4436b-3p	CLIP-seq
MIRT1170472	hsa-miR-4465	CLIP-seq
MIRT1170473	hsa-miR-4475	CLIP-seq
MIRT1170474	hsa-miR-4514	CLIP-seq
MIRT1170475	hsa-miR-4645-5p	CLIP-seq
MIRT1170476	hsa-miR-4660	CLIP-seq
MIRT1170477	hsa-miR-4673	CLIP-seq
MIRT1170478	hsa-miR-4692	CLIP-seq
MIRT1170479	hsa-miR-4739	CLIP-seq
MIRT1170480	hsa-miR-4740-3p	CLIP-seq
MIRT1170481	hsa-miR-4747-5p	CLIP-seq
MIRT1170482	hsa-miR-4753-3p	CLIP-seq
MIRT1170483	hsa-miR-4755-3p	CLIP-seq
MIRT1170484	hsa-miR-4756-5p	CLIP-seq
MIRT1170485	hsa-miR-4761-3p	CLIP-seq
MIRT1170486	hsa-miR-4771	CLIP-seq
MIRT1170487	hsa-miR-4773	CLIP-seq
MIRT1170488	hsa-miR-491-5p	CLIP-seq
MIRT1170489	hsa-miR-5047	CLIP-seq
MIRT1170490	hsa-miR-576-3p	CLIP-seq
MIRT1170491	hsa-miR-650	CLIP-seq
MIRT1170492	hsa-miR-873	CLIP-seq
MIRT1170493	hsa-miR-939	CLIP-seq
MIRT2049108	hsa-miR-1178	CLIP-seq
MIRT1170447	hsa-miR-1258	CLIP-seq
MIRT2049109	hsa-miR-1275	CLIP-seq
MIRT1170449	hsa-miR-1297	CLIP-seq
MIRT2049110	hsa-miR-1299	CLIP-seq
MIRT1170451	hsa-miR-1321	CLIP-seq
MIRT1170452	hsa-miR-1324	CLIP-seq
MIRT2049111	hsa-miR-1470	CLIP-seq
MIRT2049112	hsa-miR-150	CLIP-seq
MIRT1170455	hsa-miR-1827	CLIP-seq
MIRT2049113	hsa-miR-197	CLIP-seq
MIRT1170457	hsa-miR-26a	CLIP-seq
MIRT1170458	hsa-miR-26b	CLIP-seq
MIRT2049114	hsa-miR-3123	CLIP-seq
MIRT1170460	hsa-miR-3162-5p	CLIP-seq
MIRT1170461	hsa-miR-3166	CLIP-seq
MIRT2049115	hsa-miR-3173-3p	CLIP-seq
MIRT1170462	hsa-miR-3175	CLIP-seq
MIRT1170463	hsa-miR-3179	CLIP-seq
MIRT2049116	hsa-miR-3192	CLIP-seq
MIRT1170464	hsa-miR-3202	CLIP-seq
MIRT1170465	hsa-miR-3612	CLIP-seq
MIRT1170466	hsa-miR-361-3p	CLIP-seq
MIRT2049117	hsa-miR-3655	CLIP-seq
MIRT2049118	hsa-miR-3670	CLIP-seq
MIRT2049119	hsa-miR-3907	CLIP-seq
MIRT1170468	hsa-miR-3919	CLIP-seq
MIRT1170469	hsa-miR-3936	CLIP-seq
MIRT1170470	hsa-miR-3944-5p	CLIP-seq
MIRT2049120	hsa-miR-4254	CLIP-seq
MIRT2049121	hsa-miR-4269	CLIP-seq
MIRT2049122	hsa-miR-4270	CLIP-seq
MIRT2049123	hsa-miR-4286	CLIP-seq
MIRT2049124	hsa-miR-4292	CLIP-seq
MIRT2049125	hsa-miR-4300	CLIP-seq
MIRT2049126	hsa-miR-4308	CLIP-seq
MIRT1170471	hsa-miR-4436b-3p	CLIP-seq
MIRT2049127	hsa-miR-4441	CLIP-seq
MIRT1170472	hsa-miR-4465	CLIP-seq
MIRT1170473	hsa-miR-4475	CLIP-seq
MIRT2049128	hsa-miR-4481	CLIP-seq
MIRT1170474	hsa-miR-4514	CLIP-seq
MIRT2049129	hsa-miR-4633-3p	CLIP-seq
MIRT1170475	hsa-miR-4645-5p	CLIP-seq
MIRT2049130	hsa-miR-4665-5p	CLIP-seq
MIRT2049131	hsa-miR-4667-3p	CLIP-seq
MIRT1170477	hsa-miR-4673	CLIP-seq
MIRT1170478	hsa-miR-4692	CLIP-seq
MIRT2049132	hsa-miR-4713-5p	CLIP-seq
MIRT1170479	hsa-miR-4739	CLIP-seq
MIRT1170480	hsa-miR-4740-3p	CLIP-seq
MIRT2049133	hsa-miR-4742-5p	CLIP-seq
MIRT2049134	hsa-miR-4745-5p	CLIP-seq
MIRT1170481	hsa-miR-4747-5p	CLIP-seq
MIRT1170483	hsa-miR-4755-3p	CLIP-seq
MIRT1170484	hsa-miR-4756-5p	CLIP-seq
MIRT1170485	hsa-miR-4761-3p	CLIP-seq
MIRT1170486	hsa-miR-4771	CLIP-seq
MIRT1170487	hsa-miR-4773	CLIP-seq
MIRT2049135	hsa-miR-4779	CLIP-seq
MIRT2049136	hsa-miR-486-5p	CLIP-seq
MIRT2049137	hsa-miR-532-3p	CLIP-seq
MIRT1170490	hsa-miR-576-3p	CLIP-seq
MIRT2049138	hsa-miR-642a	CLIP-seq
MIRT2049139	hsa-miR-649	CLIP-seq
MIRT1170491	hsa-miR-650	CLIP-seq
MIRT1170492	hsa-miR-873	CLIP-seq
MIRT2049140	hsa-miR-875-3p	CLIP-seq
MIRT2049141	hsa-miR-885-5p	CLIP-seq
MIRT2049142	hsa-miR-920	CLIP-seq
MIRT2049143	hsa-miR-940	CLIP-seq
MIRT1170446	hsa-miR-1236	CLIP-seq
MIRT1170447	hsa-miR-1258	CLIP-seq
MIRT2278180	hsa-miR-1281	CLIP-seq
MIRT1170448	hsa-miR-1289	CLIP-seq
MIRT1170449	hsa-miR-1297	CLIP-seq
MIRT2049110	hsa-miR-1299	CLIP-seq
MIRT2278181	hsa-miR-1307	CLIP-seq
MIRT1170452	hsa-miR-1324	CLIP-seq
MIRT2278182	hsa-miR-1469	CLIP-seq
MIRT2049111	hsa-miR-1470	CLIP-seq
MIRT2049113	hsa-miR-197	CLIP-seq
MIRT1170456	hsa-miR-2110	CLIP-seq
MIRT1170457	hsa-miR-26a	CLIP-seq
MIRT1170458	hsa-miR-26b	CLIP-seq
MIRT1170459	hsa-miR-3150a-3p	CLIP-seq
MIRT1170460	hsa-miR-3162-5p	CLIP-seq
MIRT1170461	hsa-miR-3166	CLIP-seq
MIRT2049115	hsa-miR-3173-3p	CLIP-seq
MIRT1170462	hsa-miR-3175	CLIP-seq
MIRT1170463	hsa-miR-3179	CLIP-seq
MIRT2278183	hsa-miR-3183	CLIP-seq
MIRT2049116	hsa-miR-3192	CLIP-seq
MIRT1170464	hsa-miR-3202	CLIP-seq
MIRT1170466	hsa-miR-361-3p	CLIP-seq
MIRT2049117	hsa-miR-3655	CLIP-seq
MIRT2049118	hsa-miR-3670	CLIP-seq
MIRT1170467	hsa-miR-3689d	CLIP-seq
MIRT1170468	hsa-miR-3919	CLIP-seq
MIRT2278184	hsa-miR-3940-5p	CLIP-seq
MIRT1170470	hsa-miR-3944-5p	CLIP-seq
MIRT2049123	hsa-miR-4286	CLIP-seq
MIRT2278185	hsa-miR-4287	CLIP-seq
MIRT2049124	hsa-miR-4292	CLIP-seq
MIRT2049126	hsa-miR-4308	CLIP-seq
MIRT1170472	hsa-miR-4465	CLIP-seq
MIRT2278186	hsa-miR-4469	CLIP-seq
MIRT2278187	hsa-miR-4507	CLIP-seq
MIRT1170474	hsa-miR-4514	CLIP-seq
MIRT2049131	hsa-miR-4667-3p	CLIP-seq
MIRT2278188	hsa-miR-4685-3p	CLIP-seq
MIRT1170478	hsa-miR-4692	CLIP-seq
MIRT2278189	hsa-miR-4723-3p	CLIP-seq
MIRT1170480	hsa-miR-4740-3p	CLIP-seq
MIRT1170481	hsa-miR-4747-5p	CLIP-seq
MIRT1170482	hsa-miR-4753-3p	CLIP-seq
MIRT1170486	hsa-miR-4771	CLIP-seq
MIRT1170487	hsa-miR-4773	CLIP-seq
MIRT2049135	hsa-miR-4779	CLIP-seq
MIRT2278190	hsa-miR-4789-5p	CLIP-seq
MIRT1170488	hsa-miR-491-5p	CLIP-seq
MIRT2049137	hsa-miR-532-3p	CLIP-seq
MIRT2278191	hsa-miR-566	CLIP-seq
MIRT1170490	hsa-miR-576-3p	CLIP-seq
MIRT2278192	hsa-miR-602	CLIP-seq
MIRT2049138	hsa-miR-642a	CLIP-seq
MIRT1170492	hsa-miR-873	CLIP-seq
MIRT2049140	hsa-miR-875-3p	CLIP-seq
MIRT2049141	hsa-miR-885-5p	CLIP-seq
MIRT1170493	hsa-miR-939	CLIP-seq
MIRT1170446	hsa-miR-1236	CLIP-seq
MIRT1170449	hsa-miR-1297	CLIP-seq
MIRT1170451	hsa-miR-1321	CLIP-seq
MIRT1170452	hsa-miR-1324	CLIP-seq
MIRT1170455	hsa-miR-1827	CLIP-seq
MIRT1170457	hsa-miR-26a	CLIP-seq
MIRT1170458	hsa-miR-26b	CLIP-seq
MIRT1170461	hsa-miR-3166	CLIP-seq
MIRT1170462	hsa-miR-3175	CLIP-seq
MIRT1170465	hsa-miR-3612	CLIP-seq
MIRT1170472	hsa-miR-4465	CLIP-seq
MIRT1170473	hsa-miR-4475	CLIP-seq
MIRT1170474	hsa-miR-4514	CLIP-seq
MIRT1170475	hsa-miR-4645-5p	CLIP-seq
MIRT1170477	hsa-miR-4673	CLIP-seq
MIRT1170478	hsa-miR-4692	CLIP-seq
MIRT1170479	hsa-miR-4739	CLIP-seq
MIRT1170482	hsa-miR-4753-3p	CLIP-seq
MIRT1170483	hsa-miR-4755-3p	CLIP-seq
MIRT1170484	hsa-miR-4756-5p	CLIP-seq
MIRT1170487	hsa-miR-4773	CLIP-seq
MIRT1170491	hsa-miR-650	CLIP-seq
MIRT1170492	hsa-miR-873	CLIP-seq

Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	ISS
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISS
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IEA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISS
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0042802	Function	Identical protein binding	IEA

MIM	HGNC	e!Ensembl
617861	20178	ENSG00000176182

Q86VE0

Protein name

Myb-related transcription factor, partner of profilin (Myb-related protein p42POP) (Partner of profilin)

Protein function

Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5'-YAAC[GT]G-3'. Dimerization with PFN1 reduces its DNA-binding capacity (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13873	Myb_DNA-bind_5	16 → 93	Myb/SANT-like DNA-binding domain	Domain

Sequence

MASAAAGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIA
AKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAIL
GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE
PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSP
PSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPG
TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR
SEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP

Sequence length

399

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
NEUROTIC DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HAND	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Epilepsy	Associate	37192718	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	30018400	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Inhibit	30018400	★★★★★ ★☆☆☆☆ Found in Text Mining only

MYPOP (Myb related transcription factor, partner of profilin)