Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	339327
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 546
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF546
Synonyms (NCBI Gene) Gene synonyms aliases	ZNF49
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.2

Show/Hide all(235)

miRTarBase ID	miRNA	Experiments	Reference
MIRT717929	hsa-miR-7849-3p	HITS-CLIP	19536157
MIRT717928	hsa-miR-300	HITS-CLIP	19536157
MIRT717927	hsa-miR-381-3p	HITS-CLIP	19536157
MIRT717926	hsa-miR-4666a-3p	HITS-CLIP	19536157
MIRT717925	hsa-let-7a-3p	HITS-CLIP	19536157
MIRT717924	hsa-let-7b-3p	HITS-CLIP	19536157
MIRT717923	hsa-let-7f-1-3p	HITS-CLIP	19536157
MIRT717922	hsa-miR-98-3p	HITS-CLIP	19536157
MIRT717921	hsa-miR-7977	HITS-CLIP	19536157
MIRT646787	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT663486	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT637399	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637398	hsa-miR-4769-3p	HITS-CLIP	23824327
MIRT637397	hsa-miR-6817-5p	HITS-CLIP	23824327
MIRT637396	hsa-miR-4252	HITS-CLIP	23824327
MIRT637395	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT646787	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT637399	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637399	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637398	hsa-miR-4769-3p	HITS-CLIP	23824327
MIRT637397	hsa-miR-6817-5p	HITS-CLIP	23824327
MIRT637396	hsa-miR-4252	HITS-CLIP	23824327
MIRT637395	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT495775	hsa-miR-6808-5p	PAR-CLIP	22012620
MIRT495774	hsa-miR-6893-5p	PAR-CLIP	22012620
MIRT495773	hsa-miR-940	PAR-CLIP	22012620
MIRT529470	hsa-miR-1182	PAR-CLIP	22012620
MIRT529469	hsa-miR-4781-3p	PAR-CLIP	22012620
MIRT529468	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT529467	hsa-miR-1827	PAR-CLIP	22012620
MIRT529466	hsa-miR-1207-5p	PAR-CLIP	22012620
MIRT529465	hsa-miR-4763-3p	PAR-CLIP	22012620
MIRT529464	hsa-miR-6501-5p	PAR-CLIP	22012620
MIRT529463	hsa-miR-4423-5p	PAR-CLIP	22012620
MIRT529462	hsa-miR-744-3p	PAR-CLIP	22012620
MIRT495779	hsa-miR-21-3p	PAR-CLIP	22291592
MIRT495778	hsa-miR-3591-3p	PAR-CLIP	22291592
MIRT495777	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT495776	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT495775	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT495774	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT495773	hsa-miR-940	PAR-CLIP	22291592
MIRT495772	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT495771	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT495770	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT495769	hsa-miR-4257	PAR-CLIP	22291592
MIRT495768	hsa-miR-2467-3p	PAR-CLIP	22291592
MIRT495767	hsa-miR-192-3p	PAR-CLIP	22291592
MIRT495766	hsa-miR-4776-3p	PAR-CLIP	22291592
MIRT495779	hsa-miR-21-3p	PAR-CLIP	22291592
MIRT495778	hsa-miR-3591-3p	PAR-CLIP	22291592
MIRT495777	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT495776	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT495775	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT495774	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT495773	hsa-miR-940	PAR-CLIP	22291592
MIRT495772	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT495771	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT495770	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT495769	hsa-miR-4257	PAR-CLIP	22291592
MIRT495768	hsa-miR-2467-3p	PAR-CLIP	22291592
MIRT495767	hsa-miR-192-3p	PAR-CLIP	22291592
MIRT495766	hsa-miR-4776-3p	PAR-CLIP	22291592
MIRT717929	hsa-miR-7849-3p	HITS-CLIP	19536157
MIRT717928	hsa-miR-300	HITS-CLIP	19536157
MIRT717927	hsa-miR-381-3p	HITS-CLIP	19536157
MIRT717926	hsa-miR-4666a-3p	HITS-CLIP	19536157
MIRT717925	hsa-let-7a-3p	HITS-CLIP	19536157
MIRT717924	hsa-let-7b-3p	HITS-CLIP	19536157
MIRT717923	hsa-let-7f-1-3p	HITS-CLIP	19536157
MIRT717922	hsa-miR-98-3p	HITS-CLIP	19536157
MIRT717921	hsa-miR-7977	HITS-CLIP	19536157
MIRT646787	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT663486	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT637399	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637398	hsa-miR-4769-3p	HITS-CLIP	23824327
MIRT637397	hsa-miR-6817-5p	HITS-CLIP	23824327
MIRT637396	hsa-miR-4252	HITS-CLIP	23824327
MIRT637395	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT646787	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT637399	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637399	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637398	hsa-miR-4769-3p	HITS-CLIP	23824327
MIRT637397	hsa-miR-6817-5p	HITS-CLIP	23824327
MIRT637396	hsa-miR-4252	HITS-CLIP	23824327
MIRT637395	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT495775	hsa-miR-6808-5p	PAR-CLIP	22012620
MIRT495774	hsa-miR-6893-5p	PAR-CLIP	22012620
MIRT495773	hsa-miR-940	PAR-CLIP	22012620
MIRT529470	hsa-miR-1182	PAR-CLIP	22012620
MIRT529469	hsa-miR-4781-3p	PAR-CLIP	22012620
MIRT529468	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT529467	hsa-miR-1827	PAR-CLIP	22012620
MIRT529466	hsa-miR-1207-5p	PAR-CLIP	22012620
MIRT529465	hsa-miR-4763-3p	PAR-CLIP	22012620
MIRT529464	hsa-miR-6501-5p	PAR-CLIP	22012620
MIRT529463	hsa-miR-4423-5p	PAR-CLIP	22012620
MIRT529462	hsa-miR-744-3p	PAR-CLIP	22012620
MIRT495779	hsa-miR-21-3p	PAR-CLIP	22291592
MIRT495778	hsa-miR-3591-3p	PAR-CLIP	22291592
MIRT495777	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT495776	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT495775	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT495774	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT495773	hsa-miR-940	PAR-CLIP	22291592
MIRT495772	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT495771	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT495770	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT495769	hsa-miR-4257	PAR-CLIP	22291592
MIRT495768	hsa-miR-2467-3p	PAR-CLIP	22291592
MIRT495767	hsa-miR-192-3p	PAR-CLIP	22291592
MIRT495766	hsa-miR-4776-3p	PAR-CLIP	22291592
MIRT495779	hsa-miR-21-3p	PAR-CLIP	22291592
MIRT495778	hsa-miR-3591-3p	PAR-CLIP	22291592
MIRT495777	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT495776	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT495775	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT495774	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT495773	hsa-miR-940	PAR-CLIP	22291592
MIRT495772	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT495771	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT495770	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT495769	hsa-miR-4257	PAR-CLIP	22291592
MIRT495768	hsa-miR-2467-3p	PAR-CLIP	22291592
MIRT495767	hsa-miR-192-3p	PAR-CLIP	22291592
MIRT495766	hsa-miR-4776-3p	PAR-CLIP	22291592
MIRT1528732	hsa-miR-1178	CLIP-seq
MIRT1528733	hsa-miR-1200	CLIP-seq
MIRT1528734	hsa-miR-125a-3p	CLIP-seq
MIRT1528735	hsa-miR-146b-3p	CLIP-seq
MIRT1528736	hsa-miR-197	CLIP-seq
MIRT1528737	hsa-miR-217	CLIP-seq
MIRT1528738	hsa-miR-22	CLIP-seq
MIRT1528739	hsa-miR-24	CLIP-seq
MIRT1528740	hsa-miR-2681	CLIP-seq
MIRT1528741	hsa-miR-3123	CLIP-seq
MIRT1528742	hsa-miR-3154	CLIP-seq
MIRT1528743	hsa-miR-3173-5p	CLIP-seq
MIRT1528744	hsa-miR-3179	CLIP-seq
MIRT1528745	hsa-miR-3187-3p	CLIP-seq
MIRT1528746	hsa-miR-320a	CLIP-seq
MIRT1528747	hsa-miR-320b	CLIP-seq
MIRT1528748	hsa-miR-320c	CLIP-seq
MIRT1528749	hsa-miR-320d	CLIP-seq
MIRT1528750	hsa-miR-330-3p	CLIP-seq
MIRT1528751	hsa-miR-3545-3p	CLIP-seq
MIRT1528752	hsa-miR-3663-5p	CLIP-seq
MIRT1528753	hsa-miR-3925-5p	CLIP-seq
MIRT1528754	hsa-miR-3934	CLIP-seq
MIRT1528755	hsa-miR-3936	CLIP-seq
MIRT1528756	hsa-miR-411	CLIP-seq
MIRT1528757	hsa-miR-4269	CLIP-seq
MIRT1528758	hsa-miR-4284	CLIP-seq
MIRT1528759	hsa-miR-4292	CLIP-seq
MIRT1528760	hsa-miR-4324	CLIP-seq
MIRT1528761	hsa-miR-4429	CLIP-seq
MIRT1528762	hsa-miR-4435	CLIP-seq
MIRT1528763	hsa-miR-4438	CLIP-seq
MIRT1528764	hsa-miR-4635	CLIP-seq
MIRT1528765	hsa-miR-4680-5p	CLIP-seq
MIRT1528766	hsa-miR-4686	CLIP-seq
MIRT1528767	hsa-miR-4701-5p	CLIP-seq
MIRT1528768	hsa-miR-4716-5p	CLIP-seq
MIRT1528769	hsa-miR-4755-3p	CLIP-seq
MIRT1528770	hsa-miR-486-3p	CLIP-seq
MIRT1528771	hsa-miR-5095	CLIP-seq
MIRT1528772	hsa-miR-5096	CLIP-seq
MIRT1528773	hsa-miR-544b	CLIP-seq
MIRT1528774	hsa-miR-548s	CLIP-seq
MIRT1528775	hsa-miR-588	CLIP-seq
MIRT1528776	hsa-miR-599	CLIP-seq
MIRT1528777	hsa-miR-764	CLIP-seq
MIRT1528778	hsa-miR-767-3p	CLIP-seq
MIRT1528779	hsa-miR-874	CLIP-seq
MIRT1528732	hsa-miR-1178	CLIP-seq
MIRT1528734	hsa-miR-125a-3p	CLIP-seq
MIRT1528736	hsa-miR-197	CLIP-seq
MIRT1528741	hsa-miR-3123	CLIP-seq
MIRT1528742	hsa-miR-3154	CLIP-seq
MIRT1528744	hsa-miR-3179	CLIP-seq
MIRT1528745	hsa-miR-3187-3p	CLIP-seq
MIRT1528751	hsa-miR-3545-3p	CLIP-seq
MIRT1528752	hsa-miR-3663-5p	CLIP-seq
MIRT1528753	hsa-miR-3925-5p	CLIP-seq
MIRT1528754	hsa-miR-3934	CLIP-seq
MIRT1528755	hsa-miR-3936	CLIP-seq
MIRT1528756	hsa-miR-411	CLIP-seq
MIRT1528762	hsa-miR-4435	CLIP-seq
MIRT1528764	hsa-miR-4635	CLIP-seq
MIRT1528765	hsa-miR-4680-5p	CLIP-seq
MIRT1528766	hsa-miR-4686	CLIP-seq
MIRT1528767	hsa-miR-4701-5p	CLIP-seq
MIRT1528768	hsa-miR-4716-5p	CLIP-seq
MIRT1528769	hsa-miR-4755-3p	CLIP-seq
MIRT1528772	hsa-miR-5096	CLIP-seq
MIRT1528774	hsa-miR-548s	CLIP-seq
MIRT1528775	hsa-miR-588	CLIP-seq
MIRT1528777	hsa-miR-764	CLIP-seq
MIRT1528778	hsa-miR-767-3p	CLIP-seq
MIRT2159853	hsa-miR-1179	CLIP-seq
MIRT2159854	hsa-miR-122	CLIP-seq
MIRT2159855	hsa-miR-145	CLIP-seq
MIRT1528740	hsa-miR-2681	CLIP-seq
MIRT2159856	hsa-miR-3135b	CLIP-seq
MIRT2159857	hsa-miR-320e	CLIP-seq
MIRT2159858	hsa-miR-3925-3p	CLIP-seq
MIRT2159859	hsa-miR-4719	CLIP-seq
MIRT2159860	hsa-miR-4793-5p	CLIP-seq
MIRT2159861	hsa-miR-766	CLIP-seq
MIRT2159862	hsa-miR-944	CLIP-seq
MIRT2379230	hsa-miR-1206	CLIP-seq
MIRT2159854	hsa-miR-122	CLIP-seq
MIRT1528739	hsa-miR-24	CLIP-seq
MIRT1528740	hsa-miR-2681	CLIP-seq
MIRT2379231	hsa-miR-3074-5p	CLIP-seq
MIRT2159856	hsa-miR-3135b	CLIP-seq
MIRT2159857	hsa-miR-320e	CLIP-seq
MIRT1528758	hsa-miR-4284	CLIP-seq
MIRT2379232	hsa-miR-4466	CLIP-seq
MIRT2379233	hsa-miR-4695-3p	CLIP-seq
MIRT2379234	hsa-miR-4722-3p	CLIP-seq
MIRT2379235	hsa-miR-675	CLIP-seq
MIRT2159854	hsa-miR-122	CLIP-seq
MIRT1528739	hsa-miR-24	CLIP-seq
MIRT1528740	hsa-miR-2681	CLIP-seq
MIRT2159856	hsa-miR-3135b	CLIP-seq
MIRT2159857	hsa-miR-320e	CLIP-seq
MIRT1528758	hsa-miR-4284	CLIP-seq
MIRT1528771	hsa-miR-5095	CLIP-seq
MIRT2671299	hsa-miR-4289	CLIP-seq
MIRT2671300	hsa-miR-4687-3p	CLIP-seq
MIRT2671301	hsa-miR-4775	CLIP-seq
MIRT2671299	hsa-miR-4289	CLIP-seq
MIRT2671300	hsa-miR-4687-3p	CLIP-seq
MIRT2671301	hsa-miR-4775	CLIP-seq

Show/Hide all(5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0005634	Component	Nucleus	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q86UE3

Protein name

Zinc finger protein 546 (Zinc finger protein 49)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	59 → 100	KRAB box	Family
PF00096	zf-C2H2	217 → 239	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	245 → 267	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	273 → 295	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	301 → 323	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	329 → 351	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	357 → 379	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	385 → 407	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	413 → 435	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	441 → 463	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	469 → 494		Domain
PF00096	zf-C2H2	497 → 519	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	525 → 547	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	553 → 575	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	581 → 603	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	609 → 631	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	637 → 659	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	665 → 687	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	721 → 743	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	777 → 799	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	805 → 827	Zinc finger, C2H2 type	Domain

Sequence

MQVDPPLHGPPNDFLIFQIIPLHSLSIMPRFLWILCFSMEETQGELTSSCGSKTMANVSL
AFRDVSIDLSQEEWECLDAVQRDLYKDVMLENYSNLVSLGYTIPKPDVITLLEQEKEPWI
VMREGTRNWFTDLEYKYITKNLLSEKNVCKIYLSQLQTGEKSKNTIHEDTIFRNGLQCKH
EFERQERHQMGCVSQMLIQKQISHPLHPKIHAREKSYECKECRKAFRQQSYLIQHLRIHT
GERPYKCMECGKAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKP
YECKECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECK
VCGKTFRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGK
SFSFHAELARHRRIHTGEKPYECRECGKAFRLQTELTRHHRTHTGEKPYECKECGKAFIC
GYQLTLHLRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGEL
TRHHRIHTCEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHF
KIHTGEKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHT
GEKPYECTECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICSYRLTLHQRIHTGELP
YECKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCK
ECGKAFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQRNHISEEVLCIM

Sequence length

836

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Lupus Nephritis	Associate	29953444

ZNF546 (zinc finger protein 546)