Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	339123
Gene name Gene Name - the full gene name approved by the HGNC.	Jumonji domain containing 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	JMJD8
Synonyms (NCBI Gene) Gene synonyms aliases	C16orf20, PP14397
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16p13.3

Show/Hide all(3)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038844	hsa-miR-93-3p	CLASH	23622248
MIRT1077095	hsa-miR-361-3p	CLIP-seq
MIRT1077095	hsa-miR-361-3p	CLIP-seq

Show/Hide all(14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000987	Function	Cis-regulatory region sequence-specific DNA binding	IBA
GO:0005515	Function	Protein binding	IPI	27199445
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	29133832
GO:0005737	Component	Cytoplasm	IDA	27199445
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	29133832
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	IDA	29133832
GO:0005788	Component	Endoplasmic reticulum lumen	IEA
GO:0006110	Process	Regulation of glycolytic process	IMP	27199445
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IMP	27671354
GO:1903302	Process	Regulation of pyruvate kinase activity	IMP	27199445
GO:1903672	Process	Positive regulation of sprouting angiogenesis	IMP	27199445

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q96S16

Protein name

JmjC domain-containing protein 8 (Jumonji domain-containing protein 8)

Protein function

Functions as a positive regulator of TNF-induced NF-kappa-B signaling (PubMed:27671354). Regulates angiogenesis and cellular metabolism through interaction with PKM (PubMed:27199445).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13621	Cupin_8	52 → 261	Cupin-like domain	Domain

Sequence

MAPASRLLALWALAAVALPGSGAEGDGGWRPGGPGAVAEEERCTVERRADLTYAEFVQQY
AFVRPVILQGLTDNSRFRALCSRDRLLASFGDRVVRLSTANTYSYHKVDLPFQEYVEQLL
HPQDPTSLGNDTLYFFGDNNFTEWASLFRHYSPPPFGLLGTAPAYSFGIAGAGSGVPFHW
HGPGYSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLRDTYPALPPSARPLECTIRAGEVL
YFPDRWWHATLNLDTSVFISTFLG

Sequence length

264

Interactions

View interactions

JMJD8 (jumonji domain containing 8)