Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	338324
Gene name Gene Name - the full gene name approved by the HGNC.	S100 calcium binding protein A7A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	S100A7A
Synonyms (NCBI Gene) Gene synonyms aliases	NICE-2, NICE2, S100A15, S100A7L1, S100A7f
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q21.3

Show/Hide all(152)

miRTarBase ID	miRNA	Experiments	Reference
MIRT030254	hsa-miR-26b-5p	Microarray	19088304
MIRT646032	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT646031	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT646030	hsa-miR-3167	HITS-CLIP	23824327
MIRT646029	hsa-miR-876-5p	HITS-CLIP	23824327
MIRT646028	hsa-miR-1290	HITS-CLIP	23824327
MIRT646027	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT646026	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT646025	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT646024	hsa-miR-23c	HITS-CLIP	23824327
MIRT646023	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT646022	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT646020	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT646021	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT646018	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT646032	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT646031	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT646030	hsa-miR-3167	HITS-CLIP	23824327
MIRT646029	hsa-miR-876-5p	HITS-CLIP	23824327
MIRT646028	hsa-miR-1290	HITS-CLIP	23824327
MIRT646027	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT646026	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT646025	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT646024	hsa-miR-23c	HITS-CLIP	23824327
MIRT646023	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT646022	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT646020	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT646021	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT646018	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT1324095	hsa-miR-1200	CLIP-seq
MIRT1324096	hsa-miR-1254	CLIP-seq
MIRT1324097	hsa-miR-1255a	CLIP-seq
MIRT1324098	hsa-miR-1255b	CLIP-seq
MIRT1324099	hsa-miR-125a-3p	CLIP-seq
MIRT1324100	hsa-miR-1321	CLIP-seq
MIRT1324101	hsa-miR-2355-3p	CLIP-seq
MIRT1324102	hsa-miR-298	CLIP-seq
MIRT1324103	hsa-miR-30a	CLIP-seq
MIRT1324104	hsa-miR-30b	CLIP-seq
MIRT1324105	hsa-miR-30c	CLIP-seq
MIRT1324106	hsa-miR-30d	CLIP-seq
MIRT1324107	hsa-miR-30e	CLIP-seq
MIRT1324108	hsa-miR-3116	CLIP-seq
MIRT1324109	hsa-miR-3117-5p	CLIP-seq
MIRT1324110	hsa-miR-3125	CLIP-seq
MIRT1324111	hsa-miR-3126-5p	CLIP-seq
MIRT1324112	hsa-miR-3134	CLIP-seq
MIRT1324113	hsa-miR-3135b	CLIP-seq
MIRT1324114	hsa-miR-3165	CLIP-seq
MIRT1324115	hsa-miR-3185	CLIP-seq
MIRT1324116	hsa-miR-33a	CLIP-seq
MIRT1324117	hsa-miR-33b	CLIP-seq
MIRT1324118	hsa-miR-342-5p	CLIP-seq
MIRT1324119	hsa-miR-3612	CLIP-seq
MIRT1324120	hsa-miR-3616-3p	CLIP-seq
MIRT1324121	hsa-miR-3650	CLIP-seq
MIRT1324122	hsa-miR-3689a-3p	CLIP-seq
MIRT1324123	hsa-miR-3689c	CLIP-seq
MIRT1324124	hsa-miR-3691-5p	CLIP-seq
MIRT1324125	hsa-miR-3916	CLIP-seq
MIRT1324126	hsa-miR-3929	CLIP-seq
MIRT1324127	hsa-miR-425	CLIP-seq
MIRT1324128	hsa-miR-4305	CLIP-seq
MIRT1324129	hsa-miR-4311	CLIP-seq
MIRT1324130	hsa-miR-4314	CLIP-seq
MIRT1324131	hsa-miR-4317	CLIP-seq
MIRT1324132	hsa-miR-4324	CLIP-seq
MIRT1324133	hsa-miR-4419a	CLIP-seq
MIRT1324134	hsa-miR-4419b	CLIP-seq
MIRT1324135	hsa-miR-4436b-3p	CLIP-seq
MIRT1324136	hsa-miR-4455	CLIP-seq
MIRT1324137	hsa-miR-4478	CLIP-seq
MIRT1324138	hsa-miR-4493	CLIP-seq
MIRT1324139	hsa-miR-4499	CLIP-seq
MIRT1324140	hsa-miR-4510	CLIP-seq
MIRT1324141	hsa-miR-4513	CLIP-seq
MIRT1324142	hsa-miR-4517	CLIP-seq
MIRT1324143	hsa-miR-4534	CLIP-seq
MIRT1324144	hsa-miR-4646-3p	CLIP-seq
MIRT1324145	hsa-miR-4651	CLIP-seq
MIRT1324146	hsa-miR-4664-5p	CLIP-seq
MIRT1324147	hsa-miR-4667-5p	CLIP-seq
MIRT1324148	hsa-miR-4683	CLIP-seq
MIRT1324149	hsa-miR-4700-5p	CLIP-seq
MIRT1324150	hsa-miR-4710	CLIP-seq
MIRT1324151	hsa-miR-4719	CLIP-seq
MIRT1324152	hsa-miR-4733-3p	CLIP-seq
MIRT1324153	hsa-miR-4739	CLIP-seq
MIRT1324154	hsa-miR-4756-5p	CLIP-seq
MIRT1324155	hsa-miR-4762-3p	CLIP-seq
MIRT1324156	hsa-miR-4792	CLIP-seq
MIRT1324157	hsa-miR-4802-5p	CLIP-seq
MIRT1324158	hsa-miR-489	CLIP-seq
MIRT1324159	hsa-miR-544b	CLIP-seq
MIRT1324160	hsa-miR-608	CLIP-seq
MIRT1324161	hsa-miR-609	CLIP-seq
MIRT1324162	hsa-miR-637	CLIP-seq
MIRT1324163	hsa-miR-650	CLIP-seq
MIRT1324164	hsa-miR-661	CLIP-seq
MIRT1324120	hsa-miR-3616-3p	CLIP-seq
MIRT2096209	hsa-miR-3622a-5p	CLIP-seq
MIRT2096210	hsa-miR-3657	CLIP-seq
MIRT2096211	hsa-miR-4423-3p	CLIP-seq
MIRT1324135	hsa-miR-4436b-3p	CLIP-seq
MIRT2096212	hsa-miR-4481	CLIP-seq
MIRT2096213	hsa-miR-4669	CLIP-seq
MIRT2096214	hsa-miR-4679	CLIP-seq
MIRT1324151	hsa-miR-4719	CLIP-seq
MIRT2096215	hsa-miR-4745-5p	CLIP-seq
MIRT2096216	hsa-miR-507	CLIP-seq
MIRT2096217	hsa-miR-557	CLIP-seq
MIRT2096218	hsa-miR-630	CLIP-seq
MIRT2320435	hsa-miR-1197	CLIP-seq
MIRT2320436	hsa-miR-3153	CLIP-seq
MIRT2320437	hsa-miR-3169	CLIP-seq
MIRT2320438	hsa-miR-4515	CLIP-seq
MIRT1324152	hsa-miR-4733-3p	CLIP-seq
MIRT2320439	hsa-miR-665	CLIP-seq
MIRT2458707	hsa-miR-1909	CLIP-seq
MIRT2458708	hsa-miR-214	CLIP-seq
MIRT2458709	hsa-miR-3123	CLIP-seq
MIRT2458710	hsa-miR-3619-5p	CLIP-seq
MIRT2458711	hsa-miR-3714	CLIP-seq
MIRT2458712	hsa-miR-3925-5p	CLIP-seq
MIRT2458713	hsa-miR-3976	CLIP-seq
MIRT2458714	hsa-miR-4492	CLIP-seq
MIRT2458715	hsa-miR-4498	CLIP-seq
MIRT2458716	hsa-miR-4505	CLIP-seq
MIRT2458717	hsa-miR-761	CLIP-seq
MIRT2458718	hsa-miR-762	CLIP-seq
MIRT2616343	hsa-miR-1297	CLIP-seq
MIRT2458707	hsa-miR-1909	CLIP-seq
MIRT2458708	hsa-miR-214	CLIP-seq
MIRT2616344	hsa-miR-26a	CLIP-seq
MIRT2616345	hsa-miR-26b	CLIP-seq
MIRT2458709	hsa-miR-3123	CLIP-seq
MIRT2458710	hsa-miR-3619-5p	CLIP-seq
MIRT2458711	hsa-miR-3714	CLIP-seq
MIRT2458712	hsa-miR-3925-5p	CLIP-seq
MIRT2458713	hsa-miR-3976	CLIP-seq
MIRT2616346	hsa-miR-4465	CLIP-seq
MIRT2458714	hsa-miR-4492	CLIP-seq
MIRT2458715	hsa-miR-4498	CLIP-seq
MIRT2458716	hsa-miR-4505	CLIP-seq
MIRT2458717	hsa-miR-761	CLIP-seq
MIRT2458718	hsa-miR-762	CLIP-seq
MIRT2616347	hsa-miR-944	CLIP-seq
MIRT2616343	hsa-miR-1297	CLIP-seq
MIRT2616344	hsa-miR-26a	CLIP-seq
MIRT2616345	hsa-miR-26b	CLIP-seq
MIRT2616346	hsa-miR-4465	CLIP-seq
MIRT2616347	hsa-miR-944	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0042802	Function	Identical protein binding	IDA	21148126
GO:0043542	Process	Endothelial cell migration	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0046914	Function	Transition metal ion binding	IEA
GO:0048306	Function	Calcium-dependent protein binding	IBA

MIM	HGNC	e!Ensembl
617427	21657	ENSG00000184330

Protein

UniProt ID

Q86SG5

Protein name

Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A)

Protein function

May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases.

PDB

4AQI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01023	S_100	6 → 45	S-100/ICaBP type calcium binding domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Overexpressed in psoriasis.

Sequence

MSNTQAERSIIGMIDMFHKYTGRDGKIEKPSLLTMMKENFPNFLSACDKKGIHYLATVFE
KKDKNEDKKIDFSEFLSLLGDIAADYHKQSHGAAPCSGGSQ

Sequence length

101

Interactions

View interactions

	KEGG		Reactome
	IL-17 signaling pathway		Metal sequestration by antimicrobial proteins

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Mastocytosis	Mastocytosis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	28498804
Arthritis Psoriatic	Associate	22402441
Breast Neoplasms	Stimulate	19136201
Carcinoma Hepatocellular	Associate	33546025
Carcinoma Non Small Cell Lung	Associate	23451142
Cholesteatoma	Associate	25093596
Esophageal Neoplasms	Associate	36588538
Inflammation	Associate	25093596
Leukemia Myeloid Acute	Associate	31919040
Lung Neoplasms	Associate	28498804
Macular Degeneration	Stimulate	29696386
Mouth Neoplasms	Associate	25029526
Neoplasm Metastasis	Stimulate	28498804
Ovarian Neoplasms	Associate	30558666, 33217795
Psoriasis	Associate	22402441

S100A7A (S100 calcium binding protein A7A)