S100A7A (S100 calcium binding protein A7A)

Gene

• Entrez ID: 338324
• Gene name: S100 calcium binding protein A7A
• Gene symbol: S100A7A
• Synonyms (NCBI Gene): NICE-2, NICE2, S100A15, S100A7L1, S100A7f
• Chromosome: 1
• Chromosome location: 1q21.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT030254	hsa-miR-26b-5p	Microarray	19088304
MIRT646032	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT646031	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT646030	hsa-miR-3167	HITS-CLIP	23824327
MIRT646029	hsa-miR-876-5p	HITS-CLIP	23824327
MIRT646028	hsa-miR-1290	HITS-CLIP	23824327
MIRT646027	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT646026	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT646025	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT646024	hsa-miR-23c	HITS-CLIP	23824327
MIRT646023	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT646022	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT646020	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT646021	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT646018	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT646032	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT646031	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT646030	hsa-miR-3167	HITS-CLIP	23824327
MIRT646029	hsa-miR-876-5p	HITS-CLIP	23824327
MIRT646028	hsa-miR-1290	HITS-CLIP	23824327
MIRT646027	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT646026	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT646025	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT646024	hsa-miR-23c	HITS-CLIP	23824327
MIRT646023	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT646022	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT646020	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT646021	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT646018	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT1324095	hsa-miR-1200	CLIP-seq
MIRT1324096	hsa-miR-1254	CLIP-seq
MIRT1324097	hsa-miR-1255a	CLIP-seq
MIRT1324098	hsa-miR-1255b	CLIP-seq
MIRT1324099	hsa-miR-125a-3p	CLIP-seq
MIRT1324100	hsa-miR-1321	CLIP-seq
MIRT1324101	hsa-miR-2355-3p	CLIP-seq
MIRT1324102	hsa-miR-298	CLIP-seq
MIRT1324103	hsa-miR-30a	CLIP-seq
MIRT1324104	hsa-miR-30b	CLIP-seq
MIRT1324105	hsa-miR-30c	CLIP-seq
MIRT1324106	hsa-miR-30d	CLIP-seq
MIRT1324107	hsa-miR-30e	CLIP-seq
MIRT1324108	hsa-miR-3116	CLIP-seq
MIRT1324109	hsa-miR-3117-5p	CLIP-seq
MIRT1324110	hsa-miR-3125	CLIP-seq
MIRT1324111	hsa-miR-3126-5p	CLIP-seq
MIRT1324112	hsa-miR-3134	CLIP-seq
MIRT1324113	hsa-miR-3135b	CLIP-seq
MIRT1324114	hsa-miR-3165	CLIP-seq
MIRT1324115	hsa-miR-3185	CLIP-seq
MIRT1324116	hsa-miR-33a	CLIP-seq
MIRT1324117	hsa-miR-33b	CLIP-seq
MIRT1324118	hsa-miR-342-5p	CLIP-seq
MIRT1324119	hsa-miR-3612	CLIP-seq
MIRT1324120	hsa-miR-3616-3p	CLIP-seq
MIRT1324121	hsa-miR-3650	CLIP-seq
MIRT1324122	hsa-miR-3689a-3p	CLIP-seq
MIRT1324123	hsa-miR-3689c	CLIP-seq
MIRT1324124	hsa-miR-3691-5p	CLIP-seq
MIRT1324125	hsa-miR-3916	CLIP-seq
MIRT1324126	hsa-miR-3929	CLIP-seq
MIRT1324127	hsa-miR-425	CLIP-seq
MIRT1324128	hsa-miR-4305	CLIP-seq
MIRT1324129	hsa-miR-4311	CLIP-seq
MIRT1324130	hsa-miR-4314	CLIP-seq
MIRT1324131	hsa-miR-4317	CLIP-seq
MIRT1324132	hsa-miR-4324	CLIP-seq
MIRT1324133	hsa-miR-4419a	CLIP-seq
MIRT1324134	hsa-miR-4419b	CLIP-seq
MIRT1324135	hsa-miR-4436b-3p	CLIP-seq
MIRT1324136	hsa-miR-4455	CLIP-seq
MIRT1324137	hsa-miR-4478	CLIP-seq
MIRT1324138	hsa-miR-4493	CLIP-seq
MIRT1324139	hsa-miR-4499	CLIP-seq
MIRT1324140	hsa-miR-4510	CLIP-seq
MIRT1324141	hsa-miR-4513	CLIP-seq
MIRT1324142	hsa-miR-4517	CLIP-seq
MIRT1324143	hsa-miR-4534	CLIP-seq
MIRT1324144	hsa-miR-4646-3p	CLIP-seq
MIRT1324145	hsa-miR-4651	CLIP-seq
MIRT1324146	hsa-miR-4664-5p	CLIP-seq
MIRT1324147	hsa-miR-4667-5p	CLIP-seq
MIRT1324148	hsa-miR-4683	CLIP-seq
MIRT1324149	hsa-miR-4700-5p	CLIP-seq
MIRT1324150	hsa-miR-4710	CLIP-seq
MIRT1324151	hsa-miR-4719	CLIP-seq
MIRT1324152	hsa-miR-4733-3p	CLIP-seq
MIRT1324153	hsa-miR-4739	CLIP-seq
MIRT1324154	hsa-miR-4756-5p	CLIP-seq
MIRT1324155	hsa-miR-4762-3p	CLIP-seq
MIRT1324156	hsa-miR-4792	CLIP-seq
MIRT1324157	hsa-miR-4802-5p	CLIP-seq
MIRT1324158	hsa-miR-489	CLIP-seq
MIRT1324159	hsa-miR-544b	CLIP-seq
MIRT1324160	hsa-miR-608	CLIP-seq
MIRT1324161	hsa-miR-609	CLIP-seq
MIRT1324162	hsa-miR-637	CLIP-seq
MIRT1324163	hsa-miR-650	CLIP-seq
MIRT1324164	hsa-miR-661	CLIP-seq
MIRT1324120	hsa-miR-3616-3p	CLIP-seq
MIRT2096209	hsa-miR-3622a-5p	CLIP-seq
MIRT2096210	hsa-miR-3657	CLIP-seq
MIRT2096211	hsa-miR-4423-3p	CLIP-seq
MIRT1324135	hsa-miR-4436b-3p	CLIP-seq
MIRT2096212	hsa-miR-4481	CLIP-seq
MIRT2096213	hsa-miR-4669	CLIP-seq
MIRT2096214	hsa-miR-4679	CLIP-seq
MIRT1324151	hsa-miR-4719	CLIP-seq
MIRT2096215	hsa-miR-4745-5p	CLIP-seq
MIRT2096216	hsa-miR-507	CLIP-seq
MIRT2096217	hsa-miR-557	CLIP-seq
MIRT2096218	hsa-miR-630	CLIP-seq
MIRT2320435	hsa-miR-1197	CLIP-seq
MIRT2320436	hsa-miR-3153	CLIP-seq
MIRT2320437	hsa-miR-3169	CLIP-seq
MIRT2320438	hsa-miR-4515	CLIP-seq
MIRT1324152	hsa-miR-4733-3p	CLIP-seq
MIRT2320439	hsa-miR-665	CLIP-seq
MIRT2458707	hsa-miR-1909	CLIP-seq
MIRT2458708	hsa-miR-214	CLIP-seq
MIRT2458709	hsa-miR-3123	CLIP-seq
MIRT2458710	hsa-miR-3619-5p	CLIP-seq
MIRT2458711	hsa-miR-3714	CLIP-seq
MIRT2458712	hsa-miR-3925-5p	CLIP-seq
MIRT2458713	hsa-miR-3976	CLIP-seq
MIRT2458714	hsa-miR-4492	CLIP-seq
MIRT2458715	hsa-miR-4498	CLIP-seq
MIRT2458716	hsa-miR-4505	CLIP-seq
MIRT2458717	hsa-miR-761	CLIP-seq
MIRT2458718	hsa-miR-762	CLIP-seq
MIRT2616343	hsa-miR-1297	CLIP-seq
MIRT2458707	hsa-miR-1909	CLIP-seq
MIRT2458708	hsa-miR-214	CLIP-seq
MIRT2616344	hsa-miR-26a	CLIP-seq
MIRT2616345	hsa-miR-26b	CLIP-seq
MIRT2458709	hsa-miR-3123	CLIP-seq
MIRT2458710	hsa-miR-3619-5p	CLIP-seq
MIRT2458711	hsa-miR-3714	CLIP-seq
MIRT2458712	hsa-miR-3925-5p	CLIP-seq
MIRT2458713	hsa-miR-3976	CLIP-seq
MIRT2616346	hsa-miR-4465	CLIP-seq
MIRT2458714	hsa-miR-4492	CLIP-seq
MIRT2458715	hsa-miR-4498	CLIP-seq
MIRT2458716	hsa-miR-4505	CLIP-seq
MIRT2458717	hsa-miR-761	CLIP-seq
MIRT2458718	hsa-miR-762	CLIP-seq
MIRT2616347	hsa-miR-944	CLIP-seq
MIRT2616343	hsa-miR-1297	CLIP-seq
MIRT2616344	hsa-miR-26a	CLIP-seq
MIRT2616345	hsa-miR-26b	CLIP-seq
MIRT2616346	hsa-miR-4465	CLIP-seq
MIRT2616347	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0042802	Function	Identical protein binding	IDA	21148126
GO:0043542	Process	Endothelial cell migration	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0046914	Function	Transition metal ion binding	IEA
GO:0048306	Function	Calcium-dependent protein binding	IBA

Other IDs

• MIM: 617427
• HGNC: 21657
• e!Ensembl: ENSG00000184330

Protein

• UniProt ID: Q86SG5
• Protein name: Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A)
• Protein function: May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases.
• PDB: 4AQI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01023	S_100	6 → 45	S-100/ICaBP type calcium binding domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Overexpressed in psoriasis.
• Sequence:

  MSNTQAERSIIGMIDMFHKYTGRDGKIEKPSLLTMMKENFPNFLSACDKKGIHYLATVFE
  KKDKNEDKKIDFSEFLSLLGDIAADYHKQSHGAAPCSGGSQ

• Sequence length: 101

Pathways

KEGG:

IL-17 signaling pathway

Reactome:

Metal sequestration by antimicrobial proteins