APLP2 (amyloid beta precursor like protein 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 334 |
| Gene name | Amyloid beta precursor like protein 2 |
| Gene symbol | APLP2 |
| Synonyms (NCBI Gene) |
APLP-2APPHAPPL2CDEBP
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| Chromosome | 11 |
| Chromosome location | 11q24.3 |
| Summary | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at |
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miRNA
miRNA information provided by mirtarbase database.
529
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q06481 | ||||||||||||||||||||||||||||||
| Protein name | Amyloid beta precursor like protein 2 (APPH) (Amyloid beta (A4) precursor-like protein 2) (Amyloid protein homolog) (Amyloid-like protein 2) (APLP-2) (CDEI box-binding protein) (CDEBP) (Sperm membrane protein YWK-II) | ||||||||||||||||||||||||||||||
| Protein function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin | ||||||||||||||||||||||||||||||
| PDB | 5JBT , 5TPT , 8RQ6 | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues. | ||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 763 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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