APLP2 (amyloid beta precursor like protein 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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334 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Amyloid beta precursor like protein 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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APLP2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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APLP-2, APPH, APPL2, CDEBP |
Chromosome
Chromosome number
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11 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q24.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||||||||||||
UniProt ID | Q06481 | ||||||||||||||||||||||||||||||
Protein name | Amyloid beta precursor like protein 2 (APPH) (Amyloid beta (A4) precursor-like protein 2) (Amyloid protein homolog) (Amyloid-like protein 2) (APLP-2) (CDEI box-binding protein) (CDEBP) (Sperm membrane protein YWK-II) | ||||||||||||||||||||||||||||||
Protein function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin | ||||||||||||||||||||||||||||||
PDB | 5JBT , 5TPT , 8RQ6 | ||||||||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues. | ||||||||||||||||||||||||||||||
Sequence |
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Sequence length | 763 | ||||||||||||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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