Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
3310
Gene name Gene Name - the full gene name approved by the HGNC.
Heat shock protein family A (Hsp70) member 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
HSPA6
Synonyms (NCBI Gene) Gene synonyms aliases
HSP70B'
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q23.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT459171 hsa-miR-3714 HITS-CLIP 21572407
MIRT459169 hsa-miR-1306-3p HITS-CLIP 21572407
MIRT459168 hsa-miR-6511a-3p HITS-CLIP 21572407
MIRT459167 hsa-miR-6511b-3p HITS-CLIP 21572407
MIRT459166 hsa-miR-605-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21044950, 32296183
GO:0005524 Function ATP binding IBA 21873635
GO:0005576 Component Extracellular region TAS
GO:0005634 Component Nucleus IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
140555 5239 ENSG00000173110
Protein
UniProt ID P17066
Protein name Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Protein function Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation
PDB 3FE1
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00012 HSP70 8 614 Hsp70 protein Family
Sequence
Sequence length 643
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Spliceosome
MAPK signaling pathway
Protein processing in endoplasmic reticulum
Endocytosis
Longevity regulating pathway - multiple species
Antigen processing and presentation
Estrogen signaling pathway
Prion disease
Legionellosis
Toxoplasmosis
Measles
Lipid and atherosclerosis
  Regulation of HSF1-mediated heat shock response
Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Arthritis Juvenile arthritis rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470 19565504
Unknown
Disease term Disease name Evidence References Source
Takayasu Arteritis Takayasu Arteritis GWAS
Inflammatory Bowel Disease Inflammatory Bowel Disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Anorectal Malformations Associate 30887706
Autistic Disorder Associate 18378158
Brain Diseases Associate 18378158
Breast Neoplasms Associate 36647876
Carcinogenesis Associate 32154766
Carcinoma Hepatocellular Associate 25798051, 28732507
Colitis Ulcerative Associate 26826017
Dental Caries Associate 27567034
Diabetes Gestational Associate 29685721
Disease Associate 31619230