DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 3301 |
| Gene name | DnaJ heat shock protein family (Hsp40) member A1 |
| Gene symbol | DNAJA1 |
| Synonyms (NCBI Gene) |
DJ-2DjA1HDJ2HSDJHSJ-2HSJ2HSPF4NEDD7hDJ-2
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| Chromosome | 9 |
| Chromosome location | 9p21.1 |
| Summary | This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are cha |
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miRNA
miRNA information provided by mirtarbase database.
532
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
47
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P31689 | ||||||||||||||||||||
| Protein name | DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2) | ||||||||||||||||||||
| Protein function | Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone | ||||||||||||||||||||
| PDB | 2LO1 , 2M6Y , 6E8M , 8E2O | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver. {ECO:0000269|PubMed:10816573, ECO:0000269|PubMed:15595953}. | ||||||||||||||||||||
| Sequence | |||||||||||||||||||||
| Sequence length | 397 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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