ACADL (acyl-CoA dehydrogenase long chain)

Gene

• Entrez ID: 33
• Gene name: Acyl-CoA dehydrogenase long chain
• Gene symbol: ACADL
• Synonyms (NCBI Gene): ACAD4, LCAD
• Chromosome: 2
• Chromosome location: 2q34
• Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initi

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022288	hsa-miR-124-3p	Microarray	18668037
MIRT715136	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT715135	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT715134	hsa-miR-3183	HITS-CLIP	19536157
MIRT715133	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT715132	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT715131	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT715130	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT715129	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT715128	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT715127	hsa-miR-4279	HITS-CLIP	19536157
MIRT715126	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT715125	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT715124	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT462192	hsa-miR-34b-3p	PAR-CLIP	23592263
MIRT462191	hsa-miR-1228-3p	PAR-CLIP	23592263
MIRT462190	hsa-miR-383-3p	PAR-CLIP	23592263
MIRT462189	hsa-miR-6089	PAR-CLIP	23592263
MIRT462188	hsa-miR-6134	PAR-CLIP	23592263
MIRT462186	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT462187	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT462185	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT462184	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT462183	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT462182	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT462181	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT462180	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT462179	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT462178	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT462177	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT462176	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT462175	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT462174	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT462173	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT462172	hsa-miR-3689c	PAR-CLIP	23592263
MIRT462170	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT462171	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT462169	hsa-miR-450a-1-3p	PAR-CLIP	23592263
MIRT462168	hsa-miR-3122	PAR-CLIP	23592263
MIRT462167	hsa-miR-3913-5p	PAR-CLIP	23592263
MIRT462166	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT462164	hsa-miR-6513-5p	PAR-CLIP	23592263
MIRT715136	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT715135	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT715134	hsa-miR-3183	HITS-CLIP	19536157
MIRT715133	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT715132	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT715131	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT715130	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT715129	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT715128	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT715127	hsa-miR-4279	HITS-CLIP	19536157
MIRT715126	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT715125	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT715124	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT462192	hsa-miR-34b-3p	PAR-CLIP	23592263
MIRT462191	hsa-miR-1228-3p	PAR-CLIP	23592263
MIRT462190	hsa-miR-383-3p	PAR-CLIP	23592263
MIRT462189	hsa-miR-6089	PAR-CLIP	23592263
MIRT462188	hsa-miR-6134	PAR-CLIP	23592263
MIRT462186	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT462187	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT462185	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT462184	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT462183	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT462182	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT462181	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT462180	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT462179	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT462178	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT462177	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT462176	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT462175	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT462174	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT462173	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT462172	hsa-miR-3689c	PAR-CLIP	23592263
MIRT462170	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT462171	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT462169	hsa-miR-450a-1-3p	PAR-CLIP	23592263
MIRT462168	hsa-miR-3122	PAR-CLIP	23592263
MIRT462167	hsa-miR-3913-5p	PAR-CLIP	23592263
MIRT462166	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT462164	hsa-miR-6513-5p	PAR-CLIP	23592263
MIRT761440	hsa-miR-323-3p	CLIP-seq
MIRT761441	hsa-miR-3682-5p	CLIP-seq
MIRT761442	hsa-miR-4684-3p	CLIP-seq
MIRT761443	hsa-miR-4699-3p	CLIP-seq
MIRT761444	hsa-miR-4724-3p	CLIP-seq
MIRT761445	hsa-miR-518a-5p	CLIP-seq
MIRT761446	hsa-miR-527	CLIP-seq
MIRT1920213	hsa-miR-4289	CLIP-seq
MIRT1920213	hsa-miR-4289	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
PPARA	Unknown	20110263

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000062	Function	Fatty-acyl-CoA binding	IEA
GO:0001659	Process	Temperature homeostasis	ISS
GO:0003995	Function	Acyl-CoA dehydrogenase activity	IBA	21873635
GO:0004466	Function	Long-chain-acyl-CoA dehydrogenase activity	IBA	21873635
GO:0004466	Function	Long-chain-acyl-CoA dehydrogenase activity	ISS
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0006635	Process	Fatty acid beta-oxidation	TAS
GO:0016401	Function	Palmitoyl-CoA oxidase activity	IBA	21873635
GO:0016401	Function	Palmitoyl-CoA oxidase activity	ISS
GO:0019254	Process	Carnitine metabolic process, CoA-linked	IBA	21873635
GO:0019254	Process	Carnitine metabolic process, CoA-linked	ISS
GO:0031966	Component	Mitochondrial membrane	IEA
GO:0033539	Process	Fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA	21873635
GO:0033539	Process	Fatty acid beta-oxidation using acyl-CoA dehydrogenase	ISS
GO:0042413	Process	Carnitine catabolic process	ISS
GO:0042758	Process	Long-chain fatty acid catabolic process	IBA	21873635
GO:0042802	Function	Identical protein binding	IEA
GO:0044242	Process	Cellular lipid catabolic process	ISS
GO:0045717	Process	Negative regulation of fatty acid biosynthetic process	ISS
GO:0046322	Process	Negative regulation of fatty acid oxidation	ISS
GO:0050660	Function	Flavin adenine dinucleotide binding	IBA	21873635
GO:0090181	Process	Regulation of cholesterol metabolic process	ISS
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	ISS	9802886

Other IDs

• MIM: 609576
• HGNC: 88
• e!Ensembl: ENSG00000115361

Protein

• UniProt ID: P28330
• Protein name: Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)
• Protein function: Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of
• PDB: 8W0T, 8W0U, 8W0Z
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02771	Acyl-CoA_dh_N	54 → 165	Acyl-CoA dehydrogenase, N-terminal domain	Domain
  PF02770	Acyl-CoA_dh_M	169 → 266	Acyl-CoA dehydrogenase, middle domain	Domain
  PF00441	Acyl-CoA_dh_1	278 → 427	Acyl-CoA dehydrogenase, C-terminal domain	Domain

• Sequence:

  MAARLLRGSLRVLGGHRAPRQLPAARCSHSGGEERLETPSAKKLTDIGIRRIFSPEHDIF
  RKSVRKFFQEEVIPHHSEWEKAGEVSREVWEKAGKQGLLGVNIAEHLGGIGGDLYSAAIV
  WEEQAYSNCSGPGFSIHSGIVMSYITNHGSEEQIKHFIPQMTAGKCIGAIAMTEPGAGSD
  LQGIKTNAKKDGSDWILNGSKVFISNGSLSDVVIVVAVTNHEAPSPAHGISLFLVENGMK
  GFIKGRKLHKMGLKAQDTAELFFEDIRLPASALLGEENKGFYYIMKELPQERLLIADVAI
  SASEFMFEETRNYVKQRKAFGKTVAHLQTVQHKLAELKTHICVTRAFVDNCLQLHEAKRL
  DSATACMAKYWASELQNSVAYDCVQLHGGWGYMWEYPIAKAYVDARVQPIYGGTNEIMKE
  LIAREIVFDK

• Sequence length: 430

Pathways

KEGG:

Fatty acid degradation
Metabolic pathways
Fatty acid metabolism
PPAR signaling pathway

Reactome:

Beta oxidation of myristoyl-CoA to lauroyl-CoA
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Acyl coa dehydrogenase deficiency	Long chain acyl-CoA dehydrogenase deficiency	rs2142981921, rs113690956, rs118204014, rs387906249, rs387906251, rs118204015, rs118204017, rs118204018, rs118204016, rs2309689, rs113994170, rs113994171, rs113994168, rs113994167, rs368949613, rs387907041, rs387907042, rs115532916, rs377022708, rs398123080, rs398123082, rs398123083, rs369560930, rs398123090, rs398123091, rs398123092, rs387906252, rs727503791, rs140629318, rs727503788, rs727503794, rs786204713, rs786204738, rs786204536, rs753108198, rs794727112, rs794727113, rs796051912, rs1555527877, rs545215807, rs796051913, rs771874163, rs112406105, rs748077880, rs766742117, rs796051916, rs751995154, rs796051917, rs863224844, rs753711253, rs149753643, rs150283105, rs770127110, rs769280599, rs886044671, rs749159573, rs1057516817, rs1057517012, rs1057516979, rs1057517130, rs1057516369, rs1057516714, rs761204548, rs200788251, rs766192888, rs1057517180, rs1057516843, rs1057516686, rs140989450, rs1057516370, rs1057517416, rs1057517281, rs1057516818, rs1057516519, rs1057517280, rs1057517331, rs111851815, rs1057517386, rs1057516226, rs1057518752, rs761102100, rs1057518506, rs1057518411, rs138058572, rs1057520088, rs1057520507, rs1060499596, rs777282696, rs758144859, rs1064796104, rs1131691553, rs1553734044, rs1555527495, rs201676770, rs765390290, rs778786636, rs1555528937, rs1432183079, rs904631654, rs1555528737, rs748450834, rs780020193, rs1555527513, rs759775666, rs1555528304, rs1555528386, rs1329022268, rs1443151475, rs539029862, rs1555528367, rs1555529044, rs1555527464, rs747351687, rs771055189, rs1452339268, rs1555527907, rs371407903, rs768236474, rs1555528804, rs1555527732, rs113467582, rs771808680, rs1555529048, rs1555529204, rs764488310, rs1555528635, rs1555528745, rs1555527450, rs1555527532, rs1555527745, rs1555527806, rs768975918, rs1555528265, rs149467828, rs773401248, rs1555527741, rs1555528508, rs1555529004, rs1567565643, rs1416443472, rs746860401, rs1567564499, rs1567567440, rs765432568, rs1567566228, rs534647044, rs1567569262, rs1179305061, rs1576347955, rs1597520263, rs1597525249, rs1597534677, rs1597534796, rs1175359422, rs1597539537, rs1597518954, rs1597518019, rs1597537351, rs1597524963, rs1597526782, rs1597533847, rs63750670, rs1576344664, rs1281137823, rs746312225, rs866688232, rs781149699, rs2071123075, rs2071185757, rs1258134795, rs2071233789, rs2071255080, rs1197133430, rs2071288883, rs762619071, rs1214222702, rs1936041020, rs766026673, rs2071288305, rs2071345821, rs1257611357, rs1935731505	9861014, 10790204, 8356011, 6401712, 24591516
Autism	Autistic behavior	rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699, rs1553510219, rs1684182454, rs1559060428, rs1553510677, rs1576352885, rs1574152522, rs1574152672, rs1696658542
Hypertrophic cardiomyopathy	Hypertrophic Cardiomyopathy	rs63750743, rs104894655, rs121908987, rs587776643, rs28938173, rs121908989, rs121908991, rs267606977, rs267606978, rs193922384, rs121909374, rs886041030, rs886041031, rs121909375, rs121909377, rs2856655, rs587776700, rs387906397, rs104894204, rs121434470, rs104894828, rs121964855, rs121964856, rs121964858, rs74315380, rs104894724, rs104894725, rs104894727, rs104894728, rs104894729, rs104894730, rs267607127, rs2147283135, rs267607128, rs267607125, rs104894502, rs104894503, rs104894504, rs28933405, rs111033560, rs121434594, rs80338797, rs104893748, rs104894368, rs104894369, rs104894370, rs121913624, rs3218713, rs121913625, rs121913626, rs121913627, rs121913628, rs121913629, rs121913630, rs121913631, rs121913632, rs121913633, rs121913634, rs3218714, rs121913636, rs121913637, rs121913638, rs121913639, rs121913641, rs121913642, rs121913643, rs121913647, rs121913650, rs121913651, rs36211715, rs121913654, rs267606911, rs267606908, rs730880850, rs121912675, rs267606629, rs193922680, rs1600482909, rs387906898, rs199476398, rs387907079, rs199474815, rs199474703, rs199476305, rs199476306, rs199476315, rs199476316, rs199476317, rs199476321, rs199476311, rs193922649, rs36211723, rs187830361, rs193922383, rs193922386, rs193922390, rs193922697, rs387907267, rs397507520, rs727505017, rs397515888, rs397515889, rs397515891, rs397515893, rs397515894, rs397515895, rs397515896, rs397515897, rs397515903, rs397515905, rs375882485, rs397515907, rs397515910, rs397515912, rs397515916, rs397515920, rs397515925, rs397515926, rs397515931, rs397515933, rs397515934, rs397515935, rs397515937, rs397515942, rs397515943, rs397515944, rs397515947, rs397515948, rs397515952, rs397515954, rs112738974, rs111729952, rs397515960, rs397515963, rs397515965, rs397515966, rs397515970, rs397515972, rs397515973, rs397515974, rs397515975, rs397515977, rs376395543, rs397515979, rs397515982, rs397515987, rs397515990, rs397515991, rs397515992, rs397515995, rs397515997, rs397516001, rs397516005, rs113358486, rs397516006, rs397516007, rs397516008, rs397516010, rs397516013, rs397516014, rs373746463, rs397516019, rs397516020, rs397516022, rs397516023, rs397516029, rs397516031, rs397516032, rs397516035, rs397516037, rs397516038, rs397516040, rs397516042, rs397516044, rs397516047, rs397516049, rs397516052, rs397516056, rs397516057, rs397516058, rs397516059, rs397516061, rs397516067, rs397516068, rs397516070, rs397516072, rs397516073, rs397516074, rs397516076, rs397516077, rs397516080, rs201078659, rs397516082, rs397516083, rs1555122751, rs397516088, rs397516089, rs397516095, rs397516098, rs397516101, rs397516103, rs397516110, rs397516127, rs371898076, rs397516132, rs397516134, rs397516142, rs3218716, rs397516153, rs397516154, rs397516155, rs397516156, rs397516157, rs397516160, rs397516161, rs397516165, rs397516166, rs397516170, rs397516171, rs397516172, rs397516178, rs397516179, rs397516187, rs397516201, rs397516202, rs145213771, rs397516207, rs397516209, rs397516212, rs397516238, rs397516248, rs397516254, rs397516258, rs397516260, rs45516091, rs397516264, rs397516266, rs397516269, rs397516340, rs397516347, rs121917760, rs397516349, rs397516353, rs397516354, rs397516355, rs397516357, rs397516373, rs397516406, rs397516455, rs397516456, rs397516457, rs397516463, rs397516464, rs45525839, rs397516470, rs397516471, rs45578238, rs111377893, rs397516736, rs397516738, rs397516739, rs397516751, rs397516752, rs397516784, rs397517283, rs397514752, rs143697995, rs267607490, rs199472948, rs138193236, rs398123279, rs869320740, rs606231340, rs606231324, rs587779392, rs587779393, rs587782951, rs587782957, rs587782958, rs587782962, rs587782965, rs138049878, rs376897125, rs368765949, rs727504247, rs376923877, rs727504277, rs727504255, rs727504246, rs727504331, rs727503513, rs727504392, rs397516039, rs727504271, rs727504321, rs727504289, rs727504305, rs727503172, rs573821685, rs727503176, rs727503178, rs727504423, rs727503180, rs727504333, rs727503182, rs727504265, rs727503184, rs727503186, rs727503187, rs727504252, rs727504864, rs727504334, rs727503192, rs397515932, rs727504366, rs727504248, rs727504287, rs200411226, rs727503204, rs727504329, rs727504269, rs573916965, rs367947846, rs727503210, rs730880335, rs727503166, rs727504390, rs730880361, rs727504276, rs111683277, rs727503174, rs727503175, rs727504349, rs727504314, rs727504371, rs730880341, rs727504293, rs727503195, rs111437311, rs727503202, rs727503203, rs727504279, rs727505152, rs727503209, rs727503211, rs727503212, rs727503217, rs727503219, rs730880366, rs727503220, rs727504356, rs727504311, rs727503261, rs727503264, rs727504238, rs148808089, rs727503271, rs727504409, rs727503276, rs727504283, rs727503296, rs45544633, rs727503246, rs727503252, rs727503253, rs202141173, rs2754158, rs727504310, rs727503260, rs727504272, rs727504240, rs727503263, rs727504239, rs727504925, rs727504237, rs727504236, rs727505202, rs727504267, rs727503278, rs727504243, rs727504285, rs727503499, rs727503504, rs727504242, rs727504264, rs727504275, rs727503500, rs727503503, rs727503120, rs730880336, rs730880337, rs730880362, rs730880210, rs730880143, rs730880159, rs730881116, rs730881122, rs730880162, rs730880605, rs730880604, rs730880600, rs730880702, rs730880598, rs730880597, rs730880699, rs730880592, rs730880675, rs730880720, rs730880719, rs730880672, rs730880668, rs730880718, rs730880666, rs730880586, rs730880584, rs11570112, rs730880578, rs730880576, rs730880660, rs730880657, rs730880655, rs730880654, rs730880653, rs730880652, rs730880714, rs730880651, rs730880558, rs730880649, rs730880647, rs730880713, rs730880646, rs730880546, rs727503197, rs730880695, rs730880644, rs730880640, rs730880712, rs730880544, rs730880542, rs730880541, rs730880538, rs730880533, rs730880531, rs730880641, rs730880639, rs397515890, rs730880724, rs730880635, rs730880723, rs730880686, rs730880631, rs730880678, rs730880629, rs730880684, rs368121566, rs730880621, rs730880681, rs375607980, rs730880618, rs730880680, rs730880679, rs730880677, rs730880704, rs730880703, rs730880721, rs730880698, rs730880664, rs730880663, rs730880662, rs730880659, rs730880916, rs727504558, rs730880759, rs730880756, rs730880750, rs730880749, rs730880748, rs730880736, rs727504241, rs727504299, rs730880732, rs730880883, rs730880930, rs730880929, rs730880875, rs370310929, rs730880926, rs730880864, rs730880856, rs397516268, rs730880922, rs730880845, rs730880388, rs730881091, rs786204352, rs786204339, rs786204338, rs786204336, rs786204329, rs2069544, rs281865416, rs773317399, rs121913648, rs730880809, rs863224483, rs863224899, rs863224900, rs863225120, rs863225121, rs863225107, rs863225114, rs863225113, rs863225104, rs863225105, rs863225112, rs863225106, rs863225109, rs863225111, rs863225100, rs863225103, rs863225102, rs863225097, rs863225101, rs730880876, rs863225272, rs863225271, rs190228518, rs863225269, rs761507504, rs864622224, rs1057515421, rs869025470, rs869025469, rs869025461, rs869025468, rs869025460, rs869025467, rs869025466, rs869025465, rs869025464, rs869025463, rs869025459, rs869025462, rs727503512, rs876657706, rs876657705, rs876657703, rs876657702, rs727503213, rs876657884, rs878854428, rs878853831, rs878853842, rs1562999443, rs1563003848, rs1562991002, rs879255639, rs886037900, rs886037902, rs886037901, rs886038822, rs886039030, rs886039185, rs754664923, rs141019458, rs1057517766, rs1057517767, rs779650200, rs1057518030, rs1057517711, rs1057519503, rs1057520814, rs1060499673, rs1060501480, rs1060501484, rs1060501481, rs1060501478, rs1064792936, rs1060501475, rs1060501479, rs1064792935, rs1060501436, rs1060501448, rs1060501443, rs1060501452, rs1060505018, rs1060499604, rs781135153, rs1064796231, rs1064793202, rs977277400, rs1064793429, rs771929829, rs745811346, rs1114167419, rs1114167361, rs1555409659, rs1555123389, rs1131691514, rs1131692185, rs1131692058, rs1553279294, rs1555120920, rs1555121924, rs1555338319, rs1555120300, rs1555121488, rs373792537, rs1444727212, rs1555338462, rs1555120937, rs1555123629, rs794727046, rs1555123633, rs1555121172, rs1555123438, rs1555336467, rs1555338658, rs1213930919, rs1432810664, rs1555122188, rs764743402, rs974671846, rs1420159591, rs745688425, rs1555338080, rs200889953, rs1555120258, rs1298025872, rs767039057, rs1555120529, rs1555121247, rs774521272, rs1555122156, rs1555123473, rs1555123496, rs1555123597, rs1555337701, rs2856897, rs869312381, rs1555122928, rs1555123743, rs1554401581, rs1555120651, rs868819340, rs1555122053, rs730880742, rs758891557, rs1555337794, rs1555338378, rs1555338758, rs1245885836, rs1566530698, rs1566513862, rs1565629792, rs730880751, rs727504294, rs1563001548, rs1565622952, rs1565625473, rs1565626409, rs1565627536, rs1565628062, rs1565628486, rs1565631430, rs1391622163, rs1131691685, rs749007293, rs1566535491, rs1565624090, rs1565625777, rs1565631428, rs1568858210, rs1566537070, rs1565627566, rs1567864804, rs1563161306, rs1565622703, rs190765116, rs1595843598, rs1565625795, rs1565628078, rs774316050, rs1565631381, rs1565631424, rs1566531421, rs730880872, rs730880870, rs1566536418, rs1566536436, rs1565623216, rs1265248322, rs113276889, rs1562998062, rs1419032418, rs1565627615, rs1565624196, rs1595843640, rs1595846398, rs764950910, rs1600448065, rs1600462474, rs1417887060, rs1600477808, rs1600480573, rs1050997719, rs1420394583, rs1595840648, rs1595841063, rs1595843549, rs1595843758, rs1595845565, rs1595845888, rs1595846344, rs1595846475, rs1595849931, rs1595070747, rs1246272841, rs730880741, rs1173617248, rs1595085409, rs730880879, rs1299079662, rs1595848628, rs1595849603, rs1450218521, rs1571627587, rs1603037717, rs1603038411, rs1595850762, rs777702465, rs1595841736, rs1595842238, rs1595845204, rs1025692267, rs1595070689, rs1198682781, rs2095879705, rs201911056, rs727504425, rs141414377, rs1596303148, rs1595841206, rs1595844714, rs1595842632, rs1595843828, rs113709679, rs1595841552, rs1595849742, rs754529157, rs1709195189, rs1342121466, rs2095880935, rs2095883508, rs2095884984, rs2095889902, rs2095891411, rs2095898532, rs780625785, rs1892592854, rs1892948780, rs2095879167, rs1956121988, rs2095893477, rs2095894178, rs1801002279, rs1892956157
Kidney disease	Chronic Kidney Diseases	rs74315342, rs749740335, rs757649673, rs112417755, rs35138315	29545352
Myasthenia gravis	Myasthenias	rs5030818, rs121912815, rs121912817, rs121912818, rs121912821, rs75466054, rs121912822, rs121912823, rs794727516, rs764497513, rs376808313, rs1279554995, rs1554802792, rs369251527, rs372760913, rs1554802808, rs769234940, rs201439531, rs1272947184, rs757303526, rs760936252, rs1590576560, rs1838635262

Unknown
Disease term	Disease name	Evidence	References	Source
Acyl CoA Dehydrogenase Deficiency	long chain acyl-CoA dehydrogenase deficiency			GenCC

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Hepatocellular	Inhibit	37151879
Colorectal Neoplasms	Associate	32953885
Diabetes Mellitus Type 2	Inhibit	24403596
Lung Neoplasms	Associate	34970420
Meningioma	Associate	37014425
Mitochondrial Diseases	Associate	34970420
Neoplasms	Inhibit	25242319, 32961983, 37151879, 38393683
Neoplasms	Associate	40050905
Osteoarthritis	Associate	38292759
Sjogren's Syndrome	Associate	29504848
Squamous Cell Carcinoma of Head and Neck	Associate	32961983
Stomach Neoplasms	Associate	26330360