Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	3237
Gene name	Homeobox D11
Gene symbol	HOXD11
Synonyms (NCBI Gene)	HOX4HOX4F
Chromosome	2
Chromosome location	2q31.1
Summary	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene cluster

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miRTarBase ID	miRNA	Experiments	Reference
MIRT051956	hsa-let-7b-5p	CLASH	23622248
MIRT037516	hsa-miR-744-5p	CLASH	23622248
MIRT616275	hsa-miR-4706	HITS-CLIP	23824327
MIRT616276	hsa-miR-4749-5p	HITS-CLIP	23824327
MIRT037516	hsa-miR-744-5p	HITS-CLIP	23824327
MIRT616274	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616273	hsa-miR-5698	HITS-CLIP	23824327
MIRT616271	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616272	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616270	hsa-miR-6795-5p	HITS-CLIP	23824327
MIRT616269	hsa-miR-6887-5p	HITS-CLIP	23824327
MIRT616268	hsa-miR-450a-5p	HITS-CLIP	23824327
MIRT616267	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616277	hsa-miR-329-5p	HITS-CLIP	23824327
MIRT616275	hsa-miR-4706	HITS-CLIP	23824327
MIRT616276	hsa-miR-4749-5p	HITS-CLIP	23824327
MIRT037516	hsa-miR-744-5p	HITS-CLIP	23824327
MIRT616274	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616273	hsa-miR-5698	HITS-CLIP	23824327
MIRT616271	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616272	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616270	hsa-miR-6795-5p	HITS-CLIP	23824327
MIRT616269	hsa-miR-6887-5p	HITS-CLIP	23824327
MIRT616268	hsa-miR-450a-5p	HITS-CLIP	23824327
MIRT616267	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT557037	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT557036	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT557035	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT557034	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT557033	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT557032	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT557031	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT557030	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT557029	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT557028	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT557027	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT557026	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT557025	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT557024	hsa-miR-3666	PAR-CLIP	21572407
MIRT557023	hsa-miR-4295	PAR-CLIP	21572407
MIRT557022	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT557021	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT557020	hsa-miR-4326	PAR-CLIP	21572407
MIRT557019	hsa-miR-5701	PAR-CLIP	21572407
MIRT557018	hsa-miR-513a-5p	PAR-CLIP	21572407
MIRT557017	hsa-miR-27a-3p	PAR-CLIP	21572407
MIRT557016	hsa-miR-27b-3p	PAR-CLIP	21572407
MIRT557015	hsa-miR-3674	PAR-CLIP	21572407
MIRT439125	hsa-miR-10b-5p	3'LIFE	25074381
MIRT439125	hsa-miR-10b-5p	3'LIFE	25074381
MIRT616275	hsa-miR-4706	HITS-CLIP	23824327
MIRT616276	hsa-miR-4749-5p	HITS-CLIP	23824327
MIRT037516	hsa-miR-744-5p	HITS-CLIP	23824327
MIRT616274	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616273	hsa-miR-5698	HITS-CLIP	23824327
MIRT616271	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616272	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616270	hsa-miR-6795-5p	HITS-CLIP	23824327
MIRT616269	hsa-miR-6887-5p	HITS-CLIP	23824327
MIRT616268	hsa-miR-450a-5p	HITS-CLIP	23824327
MIRT616267	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616277	hsa-miR-329-5p	HITS-CLIP	23824327
MIRT616275	hsa-miR-4706	HITS-CLIP	23824327
MIRT616276	hsa-miR-4749-5p	HITS-CLIP	23824327
MIRT037516	hsa-miR-744-5p	HITS-CLIP	23824327
MIRT616274	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616273	hsa-miR-5698	HITS-CLIP	23824327
MIRT616271	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616272	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616270	hsa-miR-6795-5p	HITS-CLIP	23824327
MIRT616269	hsa-miR-6887-5p	HITS-CLIP	23824327
MIRT616268	hsa-miR-450a-5p	HITS-CLIP	23824327
MIRT616267	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT557037	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT557036	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT557035	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT557034	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT557033	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT557032	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT557031	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT557030	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT557029	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT557028	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT557027	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT557026	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT557025	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT557024	hsa-miR-3666	PAR-CLIP	21572407
MIRT557023	hsa-miR-4295	PAR-CLIP	21572407
MIRT557022	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT557021	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT557020	hsa-miR-4326	PAR-CLIP	21572407
MIRT557019	hsa-miR-5701	PAR-CLIP	21572407
MIRT557018	hsa-miR-513a-5p	PAR-CLIP	21572407
MIRT557017	hsa-miR-27a-3p	PAR-CLIP	21572407
MIRT557016	hsa-miR-27b-3p	PAR-CLIP	21572407
MIRT557015	hsa-miR-3674	PAR-CLIP	21572407
MIRT1053742	hsa-miR-3136-3p	CLIP-seq
MIRT1053743	hsa-miR-3685	CLIP-seq
MIRT2012202	hsa-miR-1262	CLIP-seq
MIRT2012203	hsa-miR-4701-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001658	Process	Branching involved in ureteric bud morphogenesis	ISS
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0009953	Process	Dorsal/ventral pattern formation	ISS
GO:0060272	Process	Embryonic skeletal joint morphogenesis	IBA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
142986	5134	ENSG00000128713

P31277

Protein name

Homeobox protein Hox-D11 (Homeobox protein Hox-4F)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12045	DUF3528	26 → 80	Protein of unknown function (DUF3528)	Family
PF12045	DUF3528	105 → 194	Protein of unknown function (DUF3528)	Family
PF00046	Homeodomain	267 → 323	Homeodomain	Domain

Sequence

MNDFDECGQSAASMYLPGCAYYVAPSDFASKPSFLSQPSSCQMTFPYSSNLAPHVQPVRE
VAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAA
EEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQ
FYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEG
SGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLS
RMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF

Sequence length

338

Interactions

View interactions

HOXD11 (homeobox D11)