Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3235
Gene name Gene Name - the full gene name approved by the HGNC.	Homeobox D9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HOXD9
Synonyms (NCBI Gene) Gene synonyms aliases	HOX4, HOX4C, Hox-4.3, Hox-5.2
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q31.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene cluster

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miRTarBase ID	miRNA	Experiments	Reference
MIRT724683	hsa-miR-3614-5p	HITS-CLIP	19536157
MIRT724682	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT715096	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT715095	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT715094	hsa-miR-6728-3p	HITS-CLIP	19536157
MIRT715093	hsa-miR-4769-3p	HITS-CLIP	19536157
MIRT715092	hsa-miR-6817-5p	HITS-CLIP	19536157
MIRT715091	hsa-miR-4713-3p	HITS-CLIP	19536157
MIRT715090	hsa-miR-4727-5p	HITS-CLIP	19536157
MIRT715089	hsa-miR-4715-3p	HITS-CLIP	19536157
MIRT536752	hsa-miR-6776-3p	PAR-CLIP	22012620
MIRT536751	hsa-miR-488-5p	PAR-CLIP	22012620
MIRT536750	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT536749	hsa-miR-2355-5p	PAR-CLIP	22012620
MIRT442589	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT442588	hsa-miR-4786-3p	PAR-CLIP	22100165
MIRT442587	hsa-miR-625-5p	PAR-CLIP	22100165
MIRT442586	hsa-miR-6795-5p	PAR-CLIP	22100165
MIRT442585	hsa-miR-6887-5p	PAR-CLIP	22100165
MIRT442584	hsa-miR-328-5p	PAR-CLIP	22100165
MIRT442583	hsa-miR-6885-5p	PAR-CLIP	22100165
MIRT442582	hsa-miR-1275	PAR-CLIP	22100165
MIRT442581	hsa-miR-4665-5p	PAR-CLIP	22100165
MIRT442579	hsa-miR-7109-5p	PAR-CLIP	22100165
MIRT442580	hsa-miR-6751-5p	PAR-CLIP	22100165
MIRT442578	hsa-miR-6803-5p	PAR-CLIP	22100165
MIRT442577	hsa-miR-450a-2-3p	PAR-CLIP	22100165
MIRT442576	hsa-miR-4260	PAR-CLIP	22100165
MIRT442575	hsa-miR-5572	PAR-CLIP	22100165
MIRT442589	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT442588	hsa-miR-4786-3p	PAR-CLIP	22100165
MIRT442587	hsa-miR-625-5p	PAR-CLIP	22100165
MIRT442586	hsa-miR-6795-5p	PAR-CLIP	22100165
MIRT442585	hsa-miR-6887-5p	PAR-CLIP	22100165
MIRT442584	hsa-miR-328-5p	PAR-CLIP	22100165
MIRT442583	hsa-miR-6885-5p	PAR-CLIP	22100165
MIRT442582	hsa-miR-1275	PAR-CLIP	22100165
MIRT442581	hsa-miR-4665-5p	PAR-CLIP	22100165
MIRT442579	hsa-miR-7109-5p	PAR-CLIP	22100165
MIRT442580	hsa-miR-6751-5p	PAR-CLIP	22100165
MIRT442578	hsa-miR-6803-5p	PAR-CLIP	22100165
MIRT442577	hsa-miR-450a-2-3p	PAR-CLIP	22100165
MIRT442576	hsa-miR-4260	PAR-CLIP	22100165
MIRT442575	hsa-miR-5572	PAR-CLIP	22100165
MIRT724683	hsa-miR-3614-5p	HITS-CLIP	19536157
MIRT724682	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT715096	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT715095	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT715094	hsa-miR-6728-3p	HITS-CLIP	19536157
MIRT715093	hsa-miR-4769-3p	HITS-CLIP	19536157
MIRT715092	hsa-miR-6817-5p	HITS-CLIP	19536157
MIRT715091	hsa-miR-4713-3p	HITS-CLIP	19536157
MIRT715090	hsa-miR-4727-5p	HITS-CLIP	19536157
MIRT715089	hsa-miR-4715-3p	HITS-CLIP	19536157
MIRT536752	hsa-miR-6776-3p	PAR-CLIP	22012620
MIRT536751	hsa-miR-488-5p	PAR-CLIP	22012620
MIRT536750	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT536749	hsa-miR-2355-5p	PAR-CLIP	22012620
MIRT442589	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT442588	hsa-miR-4786-3p	PAR-CLIP	22100165
MIRT442587	hsa-miR-625-5p	PAR-CLIP	22100165
MIRT442586	hsa-miR-6795-5p	PAR-CLIP	22100165
MIRT442585	hsa-miR-6887-5p	PAR-CLIP	22100165
MIRT442584	hsa-miR-328-5p	PAR-CLIP	22100165
MIRT442583	hsa-miR-6885-5p	PAR-CLIP	22100165
MIRT442582	hsa-miR-1275	PAR-CLIP	22100165
MIRT442581	hsa-miR-4665-5p	PAR-CLIP	22100165
MIRT442579	hsa-miR-7109-5p	PAR-CLIP	22100165
MIRT442580	hsa-miR-6751-5p	PAR-CLIP	22100165
MIRT442578	hsa-miR-6803-5p	PAR-CLIP	22100165
MIRT442577	hsa-miR-450a-2-3p	PAR-CLIP	22100165
MIRT442576	hsa-miR-4260	PAR-CLIP	22100165
MIRT442575	hsa-miR-5572	PAR-CLIP	22100165
MIRT442589	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT442588	hsa-miR-4786-3p	PAR-CLIP	22100165
MIRT442587	hsa-miR-625-5p	PAR-CLIP	22100165
MIRT442586	hsa-miR-6795-5p	PAR-CLIP	22100165
MIRT442585	hsa-miR-6887-5p	PAR-CLIP	22100165
MIRT442584	hsa-miR-328-5p	PAR-CLIP	22100165
MIRT442583	hsa-miR-6885-5p	PAR-CLIP	22100165
MIRT442582	hsa-miR-1275	PAR-CLIP	22100165
MIRT442581	hsa-miR-4665-5p	PAR-CLIP	22100165
MIRT442579	hsa-miR-7109-5p	PAR-CLIP	22100165
MIRT442580	hsa-miR-6751-5p	PAR-CLIP	22100165
MIRT442578	hsa-miR-6803-5p	PAR-CLIP	22100165
MIRT442577	hsa-miR-450a-2-3p	PAR-CLIP	22100165
MIRT442576	hsa-miR-4260	PAR-CLIP	22100165
MIRT442575	hsa-miR-5572	PAR-CLIP	22100165
MIRT1053812	hsa-miR-3120-3p	CLIP-seq
MIRT1053813	hsa-miR-570	CLIP-seq
MIRT2244601	hsa-miR-1224-5p	CLIP-seq
MIRT1053812	hsa-miR-3120-3p	CLIP-seq
MIRT2244602	hsa-miR-4751	CLIP-seq
MIRT1053813	hsa-miR-570	CLIP-seq
MIRT2547485	hsa-miR-3141	CLIP-seq
MIRT2547486	hsa-miR-3914	CLIP-seq
MIRT2547487	hsa-miR-4311	CLIP-seq
MIRT2547488	hsa-miR-4419a	CLIP-seq
MIRT2547489	hsa-miR-4477b	CLIP-seq
MIRT2547490	hsa-miR-4481	CLIP-seq
MIRT2547491	hsa-miR-4510	CLIP-seq
MIRT2547492	hsa-miR-4654	CLIP-seq
MIRT2547493	hsa-miR-4719	CLIP-seq
MIRT2547494	hsa-miR-4745-5p	CLIP-seq
MIRT2547495	hsa-miR-4769-5p	CLIP-seq

Transcription factors

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Transcription factor	Regulation	Reference
HOXD9	Activation	7926763

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	1756725
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	1756725
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	1756725
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IBA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005730	Component	Nucleolus	IDA
GO:0006351	Process	DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007338	Process	Single fertilization	IEA
GO:0007519	Process	Skeletal muscle tissue development	IEA
GO:0008344	Process	Adult locomotory behavior	IEA
GO:0009952	Process	Anterior/posterior pattern specification	IBA
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0009954	Process	Proximal/distal pattern formation	IBA
GO:0009954	Process	Proximal/distal pattern formation	IEA
GO:0010468	Process	Regulation of gene expression	IEA
GO:0030879	Process	Mammary gland development	IEA
GO:0035115	Process	Embryonic forelimb morphogenesis	IEA
GO:0035136	Process	Forelimb morphogenesis	IEA
GO:0035137	Process	Hindlimb morphogenesis	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IBA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IEA
GO:0048706	Process	Embryonic skeletal system development	IEA
GO:0048935	Process	Peripheral nervous system neuron development	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

MIM	HGNC	e!Ensembl
142982	5140	ENSG00000128709

Protein

UniProt ID

P28356

Protein name

Homeobox protein Hox-D9 (Homeobox protein Hox-4C) (Homeobox protein Hox-5.2)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04617	Hox9_act	11 → 133		Family
PF00046	Homeodomain	286 → 342	Homeodomain	Domain

Sequence

MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATA
AEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWM
EPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSS
STSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSS
EPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLEL
EKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD

Sequence length

352

Interactions

View interactions

HOXD9 (homeobox D9)