Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	3213
Gene name	Homeobox B3
Gene symbol	HOXB3
Synonyms (NCBI Gene)	HOX2HOX2GHox-2.7
Chromosome	17
Chromosome location	17q21.32
Summary	This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcriptio

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006838	hsa-miR-7-5p	Luciferase reporter assay	22705304
MIRT006839	hsa-miR-218-5p	Luciferase reporter assay	22705304
MIRT025627	hsa-miR-10a-5p	Sequencing	20371350
MIRT557091	hsa-miR-124-3p	PAR-CLIP	21572407
MIRT557090	hsa-miR-4695-5p	PAR-CLIP	21572407
MIRT557089	hsa-miR-5582-5p	PAR-CLIP	21572407
MIRT557088	hsa-miR-3929	PAR-CLIP	21572407
MIRT557087	hsa-miR-4419b	PAR-CLIP	21572407
MIRT557086	hsa-miR-4478	PAR-CLIP	21572407
MIRT557049	hsa-miR-4768-3p	PAR-CLIP	21572407
MIRT557048	hsa-miR-4459	PAR-CLIP	21572407
MIRT557047	hsa-miR-4433a-3p	PAR-CLIP	21572407
MIRT557085	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT557084	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT557083	hsa-miR-4708-3p	PAR-CLIP	21572407
MIRT557082	hsa-miR-4663	PAR-CLIP	21572407
MIRT557081	hsa-miR-4653-5p	PAR-CLIP	21572407
MIRT557080	hsa-miR-665	PAR-CLIP	21572407
MIRT557079	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT557078	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT557077	hsa-miR-4295	PAR-CLIP	21572407
MIRT557076	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT557075	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT557074	hsa-miR-3666	PAR-CLIP	21572407
MIRT557073	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT557072	hsa-miR-520b	PAR-CLIP	21572407
MIRT557071	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT557070	hsa-miR-302e	PAR-CLIP	21572407
MIRT557069	hsa-miR-520e	PAR-CLIP	21572407
MIRT557068	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT557067	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT557066	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT557065	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT557064	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT557063	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT557062	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT557061	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT557060	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT557059	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT557058	hsa-miR-3662	PAR-CLIP	21572407
MIRT557057	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT557056	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT557055	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT557054	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT287771	hsa-miR-4495	PAR-CLIP	21572407
MIRT557053	hsa-miR-3065-5p	PAR-CLIP	21572407
MIRT557052	hsa-miR-128-3p	PAR-CLIP	21572407
MIRT557051	hsa-miR-216a-3p	PAR-CLIP	21572407
MIRT557050	hsa-miR-3681-3p	PAR-CLIP	21572407
MIRT557049	hsa-miR-4768-3p	PAR-CLIP	21572407
MIRT557048	hsa-miR-4459	PAR-CLIP	21572407
MIRT557047	hsa-miR-4433a-3p	PAR-CLIP	21572407
MIRT557046	hsa-miR-885-5p	PAR-CLIP	21572407
MIRT557045	hsa-miR-6748-3p	PAR-CLIP	21572407
MIRT557044	hsa-miR-4421	PAR-CLIP	21572407
MIRT557043	hsa-miR-5699-3p	PAR-CLIP	21572407
MIRT557042	hsa-miR-342-3p	PAR-CLIP	21572407
MIRT557041	hsa-miR-27a-3p	PAR-CLIP	21572407
MIRT557040	hsa-miR-27b-3p	PAR-CLIP	21572407
MIRT557039	hsa-miR-4263	PAR-CLIP	21572407
MIRT557038	hsa-miR-2681-5p	PAR-CLIP	21572407
MIRT025627	hsa-miR-10a-5p	PAR-CLIP	21572407
MIRT506958	hsa-miR-10b-5p	PAR-CLIP	21572407
MIRT506957	hsa-miR-224-5p	PAR-CLIP	21572407
MIRT506956	hsa-miR-504-5p	PAR-CLIP	21572407
MIRT506955	hsa-miR-335-5p	PAR-CLIP	21572407
MIRT506954	hsa-miR-3671	PAR-CLIP	21572407
MIRT506953	hsa-miR-607	PAR-CLIP	21572407
MIRT547898	hsa-miR-375	PAR-CLIP	21572407
MIRT547897	hsa-miR-6739-3p	PAR-CLIP	21572407
MIRT506952	hsa-miR-5096	PAR-CLIP	21572407
MIRT025627	hsa-miR-10a-5p	PAR-CLIP	23446348
MIRT506958	hsa-miR-10b-5p	PAR-CLIP	23446348
MIRT506957	hsa-miR-224-5p	PAR-CLIP	23446348
MIRT506956	hsa-miR-504-5p	PAR-CLIP	23446348
MIRT506955	hsa-miR-335-5p	PAR-CLIP	23446348
MIRT506954	hsa-miR-3671	PAR-CLIP	23446348
MIRT506953	hsa-miR-607	PAR-CLIP	23446348
MIRT506952	hsa-miR-5096	PAR-CLIP	23446348
MIRT506958	hsa-miR-10b-5p	Luciferase reporter assayqRT-PCRWestern blot	27447302
MIRT557091	hsa-miR-124-3p	PAR-CLIP	21572407
MIRT557090	hsa-miR-4695-5p	PAR-CLIP	21572407
MIRT557089	hsa-miR-5582-5p	PAR-CLIP	21572407
MIRT557088	hsa-miR-3929	PAR-CLIP	21572407
MIRT557087	hsa-miR-4419b	PAR-CLIP	21572407
MIRT557086	hsa-miR-4478	PAR-CLIP	21572407
MIRT557049	hsa-miR-4768-3p	PAR-CLIP	21572407
MIRT557048	hsa-miR-4459	PAR-CLIP	21572407
MIRT557047	hsa-miR-4433a-3p	PAR-CLIP	21572407
MIRT557085	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT557084	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT557083	hsa-miR-4708-3p	PAR-CLIP	21572407
MIRT557082	hsa-miR-4663	PAR-CLIP	21572407
MIRT557081	hsa-miR-4653-5p	PAR-CLIP	21572407
MIRT557080	hsa-miR-665	PAR-CLIP	21572407
MIRT557079	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT557078	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT557077	hsa-miR-4295	PAR-CLIP	21572407
MIRT557076	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT557075	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT557074	hsa-miR-3666	PAR-CLIP	21572407
MIRT557073	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT557072	hsa-miR-520b	PAR-CLIP	21572407
MIRT557071	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT557070	hsa-miR-302e	PAR-CLIP	21572407
MIRT557069	hsa-miR-520e	PAR-CLIP	21572407
MIRT557068	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT557067	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT557066	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT557065	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT557064	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT557063	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT557062	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT557061	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT557060	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT557059	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT557058	hsa-miR-3662	PAR-CLIP	21572407
MIRT557057	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT557056	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT557055	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT557054	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT287771	hsa-miR-4495	PAR-CLIP	21572407
MIRT557053	hsa-miR-3065-5p	PAR-CLIP	21572407
MIRT557052	hsa-miR-128-3p	PAR-CLIP	21572407
MIRT557051	hsa-miR-216a-3p	PAR-CLIP	21572407
MIRT557050	hsa-miR-3681-3p	PAR-CLIP	21572407
MIRT557049	hsa-miR-4768-3p	PAR-CLIP	21572407
MIRT557048	hsa-miR-4459	PAR-CLIP	21572407
MIRT557047	hsa-miR-4433a-3p	PAR-CLIP	21572407
MIRT557046	hsa-miR-885-5p	PAR-CLIP	21572407
MIRT557045	hsa-miR-6748-3p	PAR-CLIP	21572407
MIRT557044	hsa-miR-4421	PAR-CLIP	21572407
MIRT557043	hsa-miR-5699-3p	PAR-CLIP	21572407
MIRT557042	hsa-miR-342-3p	PAR-CLIP	21572407
MIRT557041	hsa-miR-27a-3p	PAR-CLIP	21572407
MIRT557040	hsa-miR-27b-3p	PAR-CLIP	21572407
MIRT557039	hsa-miR-4263	PAR-CLIP	21572407
MIRT557038	hsa-miR-2681-5p	PAR-CLIP	21572407
MIRT025627	hsa-miR-10a-5p	PAR-CLIP	21572407
MIRT506958	hsa-miR-10b-5p	PAR-CLIP	21572407
MIRT506957	hsa-miR-224-5p	PAR-CLIP	21572407
MIRT506956	hsa-miR-504-5p	PAR-CLIP	21572407
MIRT506955	hsa-miR-335-5p	PAR-CLIP	21572407
MIRT506954	hsa-miR-3671	PAR-CLIP	21572407
MIRT506953	hsa-miR-607	PAR-CLIP	21572407
MIRT547898	hsa-miR-375	PAR-CLIP	21572407
MIRT547897	hsa-miR-6739-3p	PAR-CLIP	21572407
MIRT506952	hsa-miR-5096	PAR-CLIP	21572407
MIRT025627	hsa-miR-10a-5p	PAR-CLIP	23446348
MIRT506958	hsa-miR-10b-5p	PAR-CLIP	23446348
MIRT506957	hsa-miR-224-5p	PAR-CLIP	23446348
MIRT506956	hsa-miR-504-5p	PAR-CLIP	23446348
MIRT506955	hsa-miR-335-5p	PAR-CLIP	23446348
MIRT506954	hsa-miR-3671	PAR-CLIP	23446348
MIRT506953	hsa-miR-607	PAR-CLIP	23446348
MIRT506952	hsa-miR-5096	PAR-CLIP	23446348
MIRT1053309	hsa-miR-1283	CLIP-seq
MIRT1053310	hsa-miR-1284	CLIP-seq
MIRT1053311	hsa-miR-3148	CLIP-seq
MIRT1053312	hsa-miR-3168	CLIP-seq
MIRT1053313	hsa-miR-3185	CLIP-seq
MIRT1053314	hsa-miR-4436a	CLIP-seq
MIRT1053315	hsa-miR-4724-5p	CLIP-seq
MIRT1053316	hsa-miR-4759	CLIP-seq
MIRT1053317	hsa-miR-548a-5p	CLIP-seq
MIRT1053318	hsa-miR-548ab	CLIP-seq
MIRT1053319	hsa-miR-548ak	CLIP-seq
MIRT1053320	hsa-miR-548b-5p	CLIP-seq
MIRT1053321	hsa-miR-548c-5p	CLIP-seq
MIRT1053322	hsa-miR-548d-5p	CLIP-seq
MIRT1053323	hsa-miR-548h	CLIP-seq
MIRT1053324	hsa-miR-548i	CLIP-seq
MIRT1053325	hsa-miR-548j	CLIP-seq
MIRT1053326	hsa-miR-548n	CLIP-seq
MIRT1053327	hsa-miR-548w	CLIP-seq
MIRT1053328	hsa-miR-548y	CLIP-seq
MIRT1053329	hsa-miR-559	CLIP-seq
MIRT1053330	hsa-miR-606	CLIP-seq
MIRT2012146	hsa-miR-1236	CLIP-seq
MIRT2012147	hsa-miR-3135b	CLIP-seq
MIRT2012148	hsa-miR-4691-5p	CLIP-seq
MIRT2451338	hsa-miR-1275	CLIP-seq
MIRT2451339	hsa-miR-4260	CLIP-seq
MIRT2451340	hsa-miR-4665-5p	CLIP-seq
MIRT2451341	hsa-miR-548c-3p	CLIP-seq
MIRT2451342	hsa-miR-625	CLIP-seq
MIRT1053309	hsa-miR-1283	CLIP-seq
MIRT2547331	hsa-miR-2682	CLIP-seq
MIRT1053311	hsa-miR-3148	CLIP-seq
MIRT1053312	hsa-miR-3168	CLIP-seq
MIRT1053313	hsa-miR-3185	CLIP-seq
MIRT2547332	hsa-miR-331-5p	CLIP-seq
MIRT2547333	hsa-miR-449c	CLIP-seq
MIRT2547334	hsa-miR-4660	CLIP-seq
MIRT1053315	hsa-miR-4724-5p	CLIP-seq
MIRT2547335	hsa-miR-4764-3p	CLIP-seq
MIRT1053317	hsa-miR-548a-5p	CLIP-seq
MIRT1053318	hsa-miR-548ab	CLIP-seq
MIRT1053319	hsa-miR-548ak	CLIP-seq
MIRT1053320	hsa-miR-548b-5p	CLIP-seq
MIRT1053321	hsa-miR-548c-5p	CLIP-seq
MIRT1053322	hsa-miR-548d-5p	CLIP-seq
MIRT1053323	hsa-miR-548h	CLIP-seq
MIRT1053324	hsa-miR-548i	CLIP-seq
MIRT1053325	hsa-miR-548j	CLIP-seq
MIRT1053326	hsa-miR-548n	CLIP-seq
MIRT1053327	hsa-miR-548w	CLIP-seq
MIRT1053328	hsa-miR-548y	CLIP-seq
MIRT1053329	hsa-miR-559	CLIP-seq
MIRT1053330	hsa-miR-606	CLIP-seq
MIRT2547336	hsa-miR-618	CLIP-seq
MIRT2547337	hsa-miR-940	CLIP-seq
MIRT1053311	hsa-miR-3148	CLIP-seq
MIRT2547332	hsa-miR-331-5p	CLIP-seq
MIRT1053317	hsa-miR-548a-5p	CLIP-seq
MIRT1053318	hsa-miR-548ab	CLIP-seq
MIRT1053319	hsa-miR-548ak	CLIP-seq
MIRT1053320	hsa-miR-548b-5p	CLIP-seq
MIRT1053321	hsa-miR-548c-5p	CLIP-seq
MIRT1053322	hsa-miR-548d-5p	CLIP-seq
MIRT1053323	hsa-miR-548h	CLIP-seq
MIRT1053324	hsa-miR-548i	CLIP-seq
MIRT1053325	hsa-miR-548j	CLIP-seq
MIRT1053326	hsa-miR-548n	CLIP-seq
MIRT1053327	hsa-miR-548w	CLIP-seq
MIRT1053328	hsa-miR-548y	CLIP-seq
MIRT1053329	hsa-miR-559	CLIP-seq

Show/Hide all (31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	7913891
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	9556594
GO:0001525	Process	Angiogenesis	IEP	17972163
GO:0002244	Process	Hematopoietic progenitor cell differentiation	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0009952	Process	Anterior/posterior pattern specification	IBA
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0021546	Process	Rhombomere development	IEA
GO:0021615	Process	Glossopharyngeal nerve morphogenesis	IEA
GO:0030878	Process	Thyroid gland development	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	9556594
GO:0048704	Process	Embryonic skeletal system morphogenesis	IBA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IEA
GO:0050767	Process	Regulation of neurogenesis	IEA
GO:0051216	Process	Cartilage development	IEA
GO:0060216	Process	Definitive hemopoiesis	IEA
GO:0060324	Process	Face development	IEA

MIM	HGNC	e!Ensembl
142966	5114	ENSG00000120093

P14651

Protein name

Homeobox protein Hox-B3 (Homeobox protein Hox-2.7) (Homeobox protein Hox-2G)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	189 → 245	Homeodomain	Domain
PF13293	DUF4074	365 → 429	Domain of unknown function (DUF4074)	Family

Sequence

MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLEGDYQRSACSLQSLGNA
APHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPG
TNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDK
SPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRR
MKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQN
AYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYAD
PLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQG
RIQEAPKLTHL

Sequence length

431

Interactions

View interactions

HOXB3 (homeobox B3)