Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3205
Gene name Gene Name - the full gene name approved by the HGNC.	Homeobox A9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HOXA9
Synonyms (NCBI Gene) Gene synonyms aliases	ABD-B, HOX1, HOX1.7, HOX1G
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p15.2
Summary Summary of gene provided in NCBI Entrez Gene.	In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic develo

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001918	hsa-miR-126-3p	GFP reporter assay, qRT-PCR, Western blot	18474618
MIRT001917	hsa-miR-145-5p	GFP reporter assay, qRT-PCR, Western blot	18474618
MIRT001917	hsa-miR-145-5p	GFP reporter assay, qRT-PCR, Western blot	18474618
MIRT001918	hsa-miR-126-3p	Luciferase reporter assay	18474618
MIRT000149	hsa-miR-210-3p	Luciferase reporter assay	19782034
MIRT016142	hsa-miR-652-3p	Sequencing	20371350
MIRT019591	hsa-miR-340-5p	Sequencing	20371350
MIRT027337	hsa-miR-101-3p	Sequencing	20371350
MIRT027927	hsa-miR-96-5p	Sequencing	20371350
MIRT028225	hsa-miR-33a-5p	Sequencing	20371350
MIRT030092	hsa-miR-26b-5p	Sequencing	20371350
MIRT030986	hsa-miR-21-5p	Microarray	18591254
MIRT031333	hsa-miR-18a-5p	Sequencing	20371350
MIRT043225	hsa-miR-324-5p	CLASH	23622248
MIRT039078	hsa-miR-769-3p	CLASH	23622248
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	22353710
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	22353710
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	22353710
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	22353710
MIRT438331	hsa-miR-142-3p	Luciferase reporter assay	24057258
MIRT053330	hsa-miR-196b-5p	ChIP-seq	24334453
MIRT030986	hsa-miR-21-5p	ChIP-seq	24334453
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay	23894305
MIRT438331	hsa-miR-142-3p	Luciferase reporter assay	24057258
MIRT053330	hsa-miR-196b-5p	ChIP-seq	24334453
MIRT030986	hsa-miR-21-5p	ChIP-seq	24334453
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay	23894305
MIRT258269	hsa-miR-3154	HITS-CLIP	23824327
MIRT657313	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT657312	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT657311	hsa-miR-4267	HITS-CLIP	23824327
MIRT657310	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT657309	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT657308	hsa-miR-4421	HITS-CLIP	23824327
MIRT657307	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT657306	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT657305	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT657304	hsa-miR-7977	HITS-CLIP	23824327
MIRT657303	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT657302	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT053330	hsa-miR-196b-5p	PAR-CLIP	20371350
MIRT547902	hsa-miR-196a-5p	PAR-CLIP	20371350
MIRT571995	hsa-miR-548ac	PAR-CLIP	20371350
MIRT571994	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT571993	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT571992	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT571991	hsa-miR-548z	PAR-CLIP	20371350
MIRT571990	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT571989	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT571988	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT571987	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT571986	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT571985	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT571984	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT547901	hsa-miR-548m	PAR-CLIP	20371350
MIRT527502	hsa-miR-6856-3p	PAR-CLIP	20371350
MIRT527501	hsa-miR-181c-3p	PAR-CLIP	20371350
MIRT103533	hsa-miR-3163	PAR-CLIP	20371350
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT547900	hsa-miR-4528	PAR-CLIP	20371350
MIRT320406	hsa-miR-1284	PAR-CLIP	20371350
MIRT547899	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT019591	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT527499	hsa-miR-421	PAR-CLIP	20371350
MIRT053330	hsa-miR-196b-5p	PAR-CLIP	20371350
MIRT547902	hsa-miR-196a-5p	PAR-CLIP	20371350
MIRT547901	hsa-miR-548m	PAR-CLIP	20371350
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT547900	hsa-miR-4528	PAR-CLIP	20371350
MIRT547899	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT019591	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT527499	hsa-miR-421	PAR-CLIP	20371350
MIRT557099	hsa-miR-182-5p	PAR-CLIP	21572407
MIRT557098	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT103531	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT557097	hsa-miR-136-3p	PAR-CLIP	21572407
MIRT557096	hsa-miR-5002-5p	PAR-CLIP	21572407
MIRT557095	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT557094	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT320463	hsa-miR-4470	PAR-CLIP	21572407
MIRT557093	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT557092	hsa-miR-1271-5p	PAR-CLIP	21572407
MIRT027927	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT053330	hsa-miR-196b-5p	PAR-CLIP	21572407
MIRT547902	hsa-miR-196a-5p	PAR-CLIP	21572407
MIRT547901	hsa-miR-548m	PAR-CLIP	21572407
MIRT103533	hsa-miR-3163	PAR-CLIP	21572407
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	21572407
MIRT547900	hsa-miR-4528	PAR-CLIP	21572407
MIRT547899	hsa-miR-3124-3p	PAR-CLIP	21572407
MIRT019591	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT527499	hsa-miR-421	PAR-CLIP	21572407
MIRT541201	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT527502	hsa-miR-6856-3p	PAR-CLIP	22012620
MIRT527501	hsa-miR-181c-3p	PAR-CLIP	22012620
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	22012620
MIRT320406	hsa-miR-1284	PAR-CLIP	22012620
MIRT320400	hsa-let-7f-2-3p	PAR-CLIP	22012620
MIRT320405	hsa-miR-1185-1-3p	PAR-CLIP	22012620
MIRT320404	hsa-miR-1185-2-3p	PAR-CLIP	22012620
MIRT527499	hsa-miR-421	PAR-CLIP	22012620
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Luciferase reporter assay, qRT-PCR	26586336
MIRT053330	hsa-miR-196b-5p	Microarray, qRT-PCR	33611311
MIRT053330	hsa-miR-196b-5p	Microarray, qRT-PCR	33611311
MIRT557099	hsa-miR-182-5p	Luciferase reporter assay, Western blotting, qRT-PCR	31906958
MIRT000149	hsa-miR-210-3p	Western blotting, Luciferase reporter assay, qRT-PCR	31875764
MIRT733218	hsa-miR-19b-3p	Luciferase reporter assay, Western blotting, qRT-PCR	31564891
MIRT734806	hsa-miR-652-5p	Luciferase reporter assay, Western blotting, qRT-PCR	31740654
MIRT735757	hsa-miR-186-5p	Luciferase reporter assay, Western blotting, qRT-PCR	31802902
MIRT258269	hsa-miR-3154	HITS-CLIP	23824327
MIRT657313	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT657312	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT657311	hsa-miR-4267	HITS-CLIP	23824327
MIRT657310	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT657309	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT657308	hsa-miR-4421	HITS-CLIP	23824327
MIRT657307	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT657306	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT657305	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT657304	hsa-miR-7977	HITS-CLIP	23824327
MIRT657303	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT657302	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT053330	hsa-miR-196b-5p	PAR-CLIP	20371350
MIRT547902	hsa-miR-196a-5p	PAR-CLIP	20371350
MIRT571995	hsa-miR-548ac	PAR-CLIP	20371350
MIRT571994	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT571993	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT571992	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT571991	hsa-miR-548z	PAR-CLIP	20371350
MIRT571990	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT571989	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT571988	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT571987	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT571986	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT571985	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT571984	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT547901	hsa-miR-548m	PAR-CLIP	20371350
MIRT527502	hsa-miR-6856-3p	PAR-CLIP	20371350
MIRT527501	hsa-miR-181c-3p	PAR-CLIP	20371350
MIRT103533	hsa-miR-3163	PAR-CLIP	20371350
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT547900	hsa-miR-4528	PAR-CLIP	20371350
MIRT320406	hsa-miR-1284	PAR-CLIP	20371350
MIRT547899	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT019591	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT527499	hsa-miR-421	PAR-CLIP	20371350
MIRT053330	hsa-miR-196b-5p	PAR-CLIP	20371350
MIRT547902	hsa-miR-196a-5p	PAR-CLIP	20371350
MIRT547901	hsa-miR-548m	PAR-CLIP	20371350
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT547900	hsa-miR-4528	PAR-CLIP	20371350
MIRT547899	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT019591	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT527499	hsa-miR-421	PAR-CLIP	20371350
MIRT557099	hsa-miR-182-5p	PAR-CLIP	21572407
MIRT557098	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT103531	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT557097	hsa-miR-136-3p	PAR-CLIP	21572407
MIRT557096	hsa-miR-5002-5p	PAR-CLIP	21572407
MIRT557095	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT557094	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT320463	hsa-miR-4470	PAR-CLIP	21572407
MIRT557093	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT557092	hsa-miR-1271-5p	PAR-CLIP	21572407
MIRT027927	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT053330	hsa-miR-196b-5p	PAR-CLIP	21572407
MIRT547902	hsa-miR-196a-5p	PAR-CLIP	21572407
MIRT547901	hsa-miR-548m	PAR-CLIP	21572407
MIRT103533	hsa-miR-3163	PAR-CLIP	21572407
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	21572407
MIRT547900	hsa-miR-4528	PAR-CLIP	21572407
MIRT547899	hsa-miR-3124-3p	PAR-CLIP	21572407
MIRT019591	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT527499	hsa-miR-421	PAR-CLIP	21572407
MIRT541201	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT527502	hsa-miR-6856-3p	PAR-CLIP	22012620
MIRT527501	hsa-miR-181c-3p	PAR-CLIP	22012620
MIRT527500	hsa-miR-4709-5p	PAR-CLIP	22012620
MIRT320406	hsa-miR-1284	PAR-CLIP	22012620
MIRT320400	hsa-let-7f-2-3p	PAR-CLIP	22012620
MIRT320405	hsa-miR-1185-1-3p	PAR-CLIP	22012620
MIRT320404	hsa-miR-1185-2-3p	PAR-CLIP	22012620
MIRT527499	hsa-miR-421	PAR-CLIP	22012620
MIRT756085	hsa-miR-139-5p	Luciferase reporter assay, Western blotting, qRT-PCR, Immunoprecipitaion (IP)	35800618
MIRT756085	hsa-miR-139-5p	Luciferase reporter assay, Western blotting, qRT-PCR, Immunoprecipitaion (IP)	35800618
MIRT1053270	hsa-miR-1193	CLIP-seq
MIRT1053271	hsa-miR-133a	CLIP-seq
MIRT1053272	hsa-miR-133b	CLIP-seq
MIRT1053273	hsa-miR-147b	CLIP-seq
MIRT1053274	hsa-miR-210	CLIP-seq
MIRT1053275	hsa-miR-2113	CLIP-seq
MIRT1053276	hsa-miR-3153	CLIP-seq
MIRT1053277	hsa-miR-3165	CLIP-seq
MIRT1053278	hsa-miR-4282	CLIP-seq
MIRT1053279	hsa-miR-4420	CLIP-seq
MIRT1053280	hsa-miR-4646-5p	CLIP-seq
MIRT1053281	hsa-miR-4668-5p	CLIP-seq
MIRT1053282	hsa-miR-4706	CLIP-seq
MIRT1053283	hsa-miR-4749-5p	CLIP-seq
MIRT1053284	hsa-miR-542-5p	CLIP-seq
MIRT1053285	hsa-miR-744	CLIP-seq
MIRT1549598	hsa-let-7a	CLIP-seq
MIRT1549599	hsa-let-7b	CLIP-seq
MIRT1549600	hsa-let-7c	CLIP-seq
MIRT1549601	hsa-let-7d	CLIP-seq
MIRT1549602	hsa-let-7e	CLIP-seq
MIRT1549603	hsa-let-7f	CLIP-seq
MIRT1549604	hsa-let-7g	CLIP-seq
MIRT1549605	hsa-let-7i	CLIP-seq
MIRT1549606	hsa-miR-1245b-5p	CLIP-seq
MIRT1053271	hsa-miR-133a	CLIP-seq
MIRT1053272	hsa-miR-133b	CLIP-seq
MIRT1549607	hsa-miR-199a-3p	CLIP-seq
MIRT1549608	hsa-miR-199b-3p	CLIP-seq
MIRT1549609	hsa-miR-202	CLIP-seq
MIRT1549610	hsa-miR-25	CLIP-seq
MIRT1549611	hsa-miR-3129-5p	CLIP-seq
MIRT1549612	hsa-miR-3142	CLIP-seq
MIRT1549613	hsa-miR-32	CLIP-seq
MIRT1549614	hsa-miR-363	CLIP-seq
MIRT1549615	hsa-miR-367	CLIP-seq
MIRT1549616	hsa-miR-4458	CLIP-seq
MIRT1549617	hsa-miR-4500	CLIP-seq
MIRT1549618	hsa-miR-4672	CLIP-seq
MIRT1549619	hsa-miR-518a-5p	CLIP-seq
MIRT1549620	hsa-miR-527	CLIP-seq
MIRT1549621	hsa-miR-548ae	CLIP-seq
MIRT1549622	hsa-miR-548aj	CLIP-seq
MIRT1549623	hsa-miR-548am	CLIP-seq
MIRT1549624	hsa-miR-548x	CLIP-seq
MIRT1549625	hsa-miR-606	CLIP-seq
MIRT1549626	hsa-miR-92a	CLIP-seq
MIRT1549627	hsa-miR-92b	CLIP-seq
MIRT1549628	hsa-miR-936	CLIP-seq
MIRT1549629	hsa-miR-98	CLIP-seq
MIRT1556545	hsa-miR-140-3p	CLIP-seq
MIRT2429701	hsa-miR-3065-3p	CLIP-seq
MIRT2429702	hsa-miR-365	CLIP-seq
MIRT2429703	hsa-miR-4313	CLIP-seq
MIRT2547323	hsa-miR-1251	CLIP-seq
MIRT2547324	hsa-miR-21	CLIP-seq
MIRT2429701	hsa-miR-3065-3p	CLIP-seq
MIRT2429702	hsa-miR-365	CLIP-seq
MIRT2547325	hsa-miR-3688-3p	CLIP-seq
MIRT2547326	hsa-miR-3978	CLIP-seq
MIRT2547327	hsa-miR-4277	CLIP-seq
MIRT2429703	hsa-miR-4313	CLIP-seq
MIRT2547328	hsa-miR-4694-3p	CLIP-seq
MIRT2547329	hsa-miR-4768-5p	CLIP-seq
MIRT2547330	hsa-miR-590-5p	CLIP-seq
MIRT2547323	hsa-miR-1251	CLIP-seq
MIRT2547324	hsa-miR-21	CLIP-seq
MIRT2429701	hsa-miR-3065-3p	CLIP-seq
MIRT2682451	hsa-miR-338-5p	CLIP-seq
MIRT2429702	hsa-miR-365	CLIP-seq
MIRT2547325	hsa-miR-3688-3p	CLIP-seq
MIRT2547326	hsa-miR-3978	CLIP-seq
MIRT2547327	hsa-miR-4277	CLIP-seq
MIRT2429703	hsa-miR-4313	CLIP-seq
MIRT2682452	hsa-miR-4691-5p	CLIP-seq
MIRT2547328	hsa-miR-4694-3p	CLIP-seq
MIRT2547329	hsa-miR-4768-5p	CLIP-seq
MIRT2547330	hsa-miR-590-5p	CLIP-seq
MIRT2682453	hsa-miR-875-5p	CLIP-seq

Transcription factors

Show/Hide all(5)

Transcription factor	Regulation	Reference
CREBBP	Activation	16849538
KAT6A	Activation	22713874;23994619
NFKB1	Repression	18068911
SALL4	Activation	24051379
SUZ12	Unknown	15225548

Show/Hide all(28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	16189514, 19060904, 22269951, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005667	Component	Transcription regulator complex	IEA
GO:0006351	Process	Transcription, DNA-templated	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0007275	Process	Multicellular organism development	TAS	8563754
GO:0007283	Process	Spermatogenesis	IEA
GO:0007338	Process	Single fertilization	IEA
GO:0008584	Process	Male gonad development	IEA
GO:0009952	Process	Anterior/posterior pattern specification	IBA	21873635
GO:0009954	Process	Proximal/distal pattern formation	IBA	21873635
GO:0019899	Function	Enzyme binding	IPI	22269951
GO:0030879	Process	Mammary gland development	IEA
GO:0035115	Process	Embryonic forelimb morphogenesis	IEA
GO:0042118	Process	Endothelial cell activation	IMP	22269951
GO:0045638	Process	Negative regulation of myeloid cell differentiation	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IBA	21873635
GO:0060065	Process	Uterus development	IEA
GO:0060216	Process	Definitive hemopoiesis	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
142956	5109	ENSG00000078399

Protein

UniProt ID

P31269

Protein name

Homeobox protein Hox-A9 (Homeobox protein Hox-1G)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothel

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04617	Hox9_act	1 → 193		Family
PF00046	Homeodomain	207 → 263	Homeodomain	Domain

Sequence

MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQSKA
TVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALS
FAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNA
ENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVA
RLLNLTERQVKIWFQNRRMKMKKINKDRAKDE

Sequence length

272

Interactions

View interactions

	KEGG
	Transcriptional misregulation in cancer

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Leukemia	Leukemia, Myelocytic, Acute, Acute Myeloid Leukemia (AML-M2)	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	22541086
Melanoma	melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340 View all (64 more)	16778180

Show/Hide Text Mining Associations (98)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	26134223, 30032824
Adenocarcinoma of Lung	Inhibit	28178989
Adenoma Islet Cell	Stimulate	30575306
Adenoma Oxyphilic	Associate	28662726
Arm Injuries	Associate	36734258
Ataxia	Associate	36734258
Atrial Fibrillation	Associate	37620966
Atypical Squamous Cells of the Cervix	Associate	16803519
Bicuspid Aortic Valve Disease	Associate	36734258
Blast Crisis	Associate	10848835
Breast Neoplasms	Associate	16766534, 27409175, 28748001, 34416888
Breast Neoplasms	Inhibit	20727230
Calcinosis	Associate	31043660
Calcinosis Cutis	Associate	22723371
Carcinogenesis	Associate	23569218
Carcinoma Hepatocellular	Associate	20079733, 20676325, 22976466, 28951629, 38062093
Carcinoma Non Small Cell Lung	Associate	24081945, 24937636, 31906958, 32430478, 36461127, 37038139
Carcinoma Ovarian Epithelial	Associate	25966226, 28387653
Carcinoma Papillary	Associate	36366735
Carcinoma Renal Cell	Associate	28662726
Carcinoma Squamous Cell	Associate	17369352
Cell Transformation Viral	Associate	19696924, 23840580
Cerulean cataract	Associate	19338047
Cholangiocarcinoma	Associate	24089088
Chordoma	Associate	28515451
Clubfoot	Associate	19938081
Colorectal Neoplasms	Associate	35743243, 36065412, 38285101
Colorectal Neoplasms Hereditary Nonpolyposis	Associate	25625843
Daneman Davy Mancer syndrome	Associate	36734258
Dyskinesias	Associate	24886209
Emanuel syndrome	Associate	10848835, 11841413, 15721637, 9074407
End Stage Liver Disease	Associate	34419462
Endometrial Neoplasms	Associate	26522113, 31787246
Epidermolysis bullosa with pyloric atresia	Associate	30850842
Esophageal Neoplasms	Associate	19472401
Esophageal Squamous Cell Carcinoma	Associate	19472401
Glioblastoma	Associate	20068170, 20935218, 21947269, 33154193
Glioma	Associate	21339190, 21947269, 30536324, 35845958
Glioma	Stimulate	35349479
Glucosephosphate Dehydrogenase Deficiency	Associate	25677060
Hand foot uterus syndrome	Associate	36734258
Head and Neck Neoplasms	Associate	24671639
Hemangioblastoma	Associate	26768750
Hematologic Neoplasms	Associate	14604967, 36192425
Hyperkeratosis Epidermolytic	Associate	31701765
Hyperplasia	Stimulate	20805992
Hypersensitivity Immediate	Associate	26134223
Inflammation	Associate	22269951, 32330594
Leukemia	Associate	11369863, 14604967, 15657436, 16709517, 20565746, 23818607, 24858818, 27317766, 33001025, 33924850, 34502319, 36139405, 36595475, 38216972
Leukemia Biphenotypic Acute	Associate	27317766
Leukemia Biphenotypic Acute	Stimulate	35981137
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	10848835, 11830496, 23894305
Leukemia Myeloid	Associate	10996203, 11830496
Leukemia Myeloid	Stimulate	17327400
Leukemia Myeloid Acute	Associate	10848835, 10936866, 11830496, 15721637, 17327400, 19696924, 20565746, 20805992, 21937451, 23840580, 25987065, 31164492, 32664447, 34502319, 36577137 View all (4 more)
Leukemia Myeloid Acute	Stimulate	14604967, 31426381
Leukemia T Cell	Associate	29384529
Lung Neoplasms	Associate	22522909, 30516882, 32138766, 37038139
Lymphatic Metastasis	Stimulate	30843252
Lymphatic Metastasis	Associate	38285101
Lymphedema Hereditary IB	Associate	30032824
Lymphoma Mantle Cell	Associate	21603610
Melanoma	Associate	28578692
Meningioma	Associate	23349797
Mouth Neoplasms	Associate	24886209
Myelodysplastic Syndromes	Associate	15982348
Myeloproliferative Disorders	Associate	19338047
Neoplasm Metastasis	Associate	24886209, 30843252, 32881299
Neoplasms	Associate	11841413, 16838325, 17369352, 17623056, 21603610, 22522909, 24067365, 25287138, 25625843, 26134223, 26332997, 27039722, 27225590, 27729459, 28387653 View all (12 more)
Neoplasms	Inhibit	20534969, 20727230, 24937636
Neoplasms	Stimulate	38285101
Neoplasms Cystic Mucinous and Serous	Associate	25625843
Neoplasms Germ Cell and Embryonal	Associate	33224314
Non Muscle Invasive Bladder Neoplasms	Associate	26332997
Obesity	Associate	34588385
Oncogene Addiction	Associate	16838325, 23894305
Ovarian Neoplasms	Associate	17623056, 25625843, 34419462, 34514844
Ovarian Neoplasms	Stimulate	36366735
Periodic fever familial autosomal dominant	Associate	20068170
Philadelphia Chromosome	Associate	10848835
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	33069783
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	12358913, 16029452, 16644881, 32103106, 36192425
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Stimulate	12637319, 15982348
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Inhibit	29384529
Prodromal Symptoms	Associate	24081945
Prostatic Neoplasms	Associate	35372588
Scleroderma Systemic	Associate	21769840
Seminoma	Associate	33224314
Squamous Cell Carcinoma of Head and Neck	Associate	21558411, 24671639, 24886209, 28780773, 29927694, 30843252, 34850551
Syndrome	Associate	36734258
Testicular Germ Cell Tumor	Associate	33224314
Thyroid Cancer Papillary	Associate	31043660
Thyroid Carcinoma Anaplastic	Associate	34719830
Urinary Bladder Neoplasms	Associate	23056278, 26332997, 27598218
Urogenital Abnormalities	Associate	36734258
Uterine Cervical Neoplasms	Inhibit	27039722
Uveal melanoma	Associate	31740654
Vascular Remodeling	Associate	21388517

HOXA9 (homeobox A9)