Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	3202
Gene name	Homeobox A5
Gene symbol	HOXA5
Synonyms (NCBI Gene)	HOX1HOX1.3HOX1C
Chromosome	7
Chromosome location	7p15.2
Summary	In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic develo

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miRTarBase ID	miRNA	Experiments	Reference
MIRT000958	hsa-miR-130a-3p	Luciferase reporter assayqRT-PCRWestern blotNorthern blot	17957028
MIRT000958	hsa-miR-130a-3p	Review	19935707
MIRT001794	hsa-miR-19a-3p	Luciferase reporter assay	14697198
MIRT006906	hsa-miR-196a-5p	Luciferase reporter assayqRT-PCRWestern blot	22876840
MIRT016043	hsa-miR-374b-5p	Sequencing	20371350
MIRT016627	hsa-miR-484	Sequencing	20371350
MIRT019581	hsa-miR-340-5p	Sequencing	20371350
MIRT020201	hsa-miR-130b-3p	Sequencing	20371350
MIRT000958	hsa-miR-130a-3p	Reporter assay;Other	17957028
MIRT025008	hsa-miR-183-5p	Sequencing	20371350
MIRT031182	hsa-miR-19b-3p	Sequencing	20371350
MIRT001794	hsa-miR-19a-3p	Reporter assay;Other	21271217
MIRT049277	hsa-miR-92a-3p	CLASH	23622248
MIRT320350	hsa-miR-200c-3p	qRT-PCR	23294929
MIRT320350	hsa-miR-200c-3p	qRT-PCR	23294929
MIRT025008	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT547915	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT547914	hsa-miR-1271-5p	PAR-CLIP	21572407
MIRT547913	hsa-miR-3666	PAR-CLIP	21572407
MIRT547912	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT547911	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT547910	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT020201	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT547909	hsa-miR-4295	PAR-CLIP	21572407
MIRT000958	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT547908	hsa-miR-8485	PAR-CLIP	21572407
MIRT258223	hsa-miR-5003-5p	PAR-CLIP	21572407
MIRT547907	hsa-miR-1909-5p	PAR-CLIP	21572407
MIRT547906	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT547905	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT547904	hsa-miR-4658	PAR-CLIP	21572407
MIRT547903	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT006906	hsa-miR-196a-5p	PAR-CLIP	23446348
MIRT513875	hsa-miR-196b-5p	PAR-CLIP	23446348
MIRT513873	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT513874	hsa-miR-3927-3p	PAR-CLIP	23446348
MIRT513872	hsa-miR-6831-5p	PAR-CLIP	23446348
MIRT513871	hsa-miR-6830-5p	PAR-CLIP	23446348
MIRT513870	hsa-miR-4457	PAR-CLIP	23446348
MIRT513868	hsa-miR-302b-5p	PAR-CLIP	23446348
MIRT513869	hsa-miR-302d-5p	PAR-CLIP	23446348
MIRT513867	hsa-miR-5585-3p	PAR-CLIP	23446348
MIRT734037	hsa-miR-891a-5p	Luciferase reporter assayWestern blottingqRT-PCR	33986868
MIRT025008	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT547915	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT547914	hsa-miR-1271-5p	PAR-CLIP	21572407
MIRT547913	hsa-miR-3666	PAR-CLIP	21572407
MIRT547912	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT547911	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT547910	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT020201	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT547909	hsa-miR-4295	PAR-CLIP	21572407
MIRT000958	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT547908	hsa-miR-8485	PAR-CLIP	21572407
MIRT258223	hsa-miR-5003-5p	PAR-CLIP	21572407
MIRT547907	hsa-miR-1909-5p	PAR-CLIP	21572407
MIRT547906	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT547905	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT547904	hsa-miR-4658	PAR-CLIP	21572407
MIRT547903	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT006906	hsa-miR-196a-5p	PAR-CLIP	23446348
MIRT513875	hsa-miR-196b-5p	PAR-CLIP	23446348
MIRT513873	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT513874	hsa-miR-3927-3p	PAR-CLIP	23446348
MIRT513872	hsa-miR-6831-5p	PAR-CLIP	23446348
MIRT513871	hsa-miR-6830-5p	PAR-CLIP	23446348
MIRT513870	hsa-miR-4457	PAR-CLIP	23446348
MIRT513868	hsa-miR-302b-5p	PAR-CLIP	23446348
MIRT513869	hsa-miR-302d-5p	PAR-CLIP	23446348
MIRT513867	hsa-miR-5585-3p	PAR-CLIP	23446348
MIRT1053201	hsa-miR-1271	CLIP-seq
MIRT1053202	hsa-miR-1278	CLIP-seq
MIRT1053203	hsa-miR-128	CLIP-seq
MIRT1053204	hsa-miR-129-5p	CLIP-seq
MIRT1053205	hsa-miR-1297	CLIP-seq
MIRT1053206	hsa-miR-1305	CLIP-seq
MIRT1053207	hsa-miR-130a	CLIP-seq
MIRT1053208	hsa-miR-130b	CLIP-seq
MIRT1053209	hsa-miR-196a	CLIP-seq
MIRT1053210	hsa-miR-196b	CLIP-seq
MIRT1053211	hsa-miR-200b	CLIP-seq
MIRT1053212	hsa-miR-200c	CLIP-seq
MIRT1053213	hsa-miR-26a	CLIP-seq
MIRT1053214	hsa-miR-26b	CLIP-seq
MIRT1053215	hsa-miR-27a	CLIP-seq
MIRT1053216	hsa-miR-27b	CLIP-seq
MIRT1053217	hsa-miR-301a	CLIP-seq
MIRT1053218	hsa-miR-301b	CLIP-seq
MIRT1053219	hsa-miR-3117-5p	CLIP-seq
MIRT1053220	hsa-miR-3179	CLIP-seq
MIRT1053221	hsa-miR-320a	CLIP-seq
MIRT1053222	hsa-miR-320b	CLIP-seq
MIRT1053223	hsa-miR-320c	CLIP-seq
MIRT1053224	hsa-miR-320d	CLIP-seq
MIRT1053225	hsa-miR-3682-5p	CLIP-seq
MIRT1053226	hsa-miR-382	CLIP-seq
MIRT1053227	hsa-miR-3927	CLIP-seq
MIRT1053228	hsa-miR-3941	CLIP-seq
MIRT1053229	hsa-miR-3977	CLIP-seq
MIRT1053230	hsa-miR-429	CLIP-seq
MIRT1053231	hsa-miR-4311	CLIP-seq
MIRT1053232	hsa-miR-4429	CLIP-seq
MIRT1053233	hsa-miR-4436a	CLIP-seq
MIRT1053234	hsa-miR-4438	CLIP-seq
MIRT1053235	hsa-miR-4465	CLIP-seq
MIRT1053236	hsa-miR-454	CLIP-seq
MIRT1053237	hsa-miR-4652-5p	CLIP-seq
MIRT1053238	hsa-miR-466	CLIP-seq
MIRT1053239	hsa-miR-4672	CLIP-seq
MIRT1053240	hsa-miR-4711-3p	CLIP-seq
MIRT1053241	hsa-miR-4713-3p	CLIP-seq
MIRT1053242	hsa-miR-4716-3p	CLIP-seq
MIRT1053243	hsa-miR-4720-3p	CLIP-seq
MIRT1053244	hsa-miR-4731-3p	CLIP-seq
MIRT1053245	hsa-miR-4789-5p	CLIP-seq
MIRT1053246	hsa-miR-4801	CLIP-seq
MIRT1053247	hsa-miR-4804-3p	CLIP-seq
MIRT1053248	hsa-miR-498	CLIP-seq
MIRT1053249	hsa-miR-5095	CLIP-seq
MIRT1053250	hsa-miR-548ac	CLIP-seq
MIRT1053251	hsa-miR-548ae	CLIP-seq
MIRT1053252	hsa-miR-548aj	CLIP-seq
MIRT1053253	hsa-miR-548am	CLIP-seq
MIRT1053254	hsa-miR-548d-3p	CLIP-seq
MIRT1053255	hsa-miR-548x	CLIP-seq
MIRT1053256	hsa-miR-548z	CLIP-seq
MIRT1053257	hsa-miR-592	CLIP-seq
MIRT1053258	hsa-miR-599	CLIP-seq
MIRT1053259	hsa-miR-802	CLIP-seq
MIRT1053260	hsa-miR-96	CLIP-seq
MIRT1053205	hsa-miR-1297	CLIP-seq
MIRT1053213	hsa-miR-26a	CLIP-seq
MIRT1053214	hsa-miR-26b	CLIP-seq
MIRT1053225	hsa-miR-3682-5p	CLIP-seq
MIRT1053229	hsa-miR-3977	CLIP-seq
MIRT1053235	hsa-miR-4465	CLIP-seq
MIRT1053259	hsa-miR-802	CLIP-seq
MIRT2012092	hsa-miR-124	CLIP-seq
MIRT1053202	hsa-miR-1278	CLIP-seq
MIRT1053203	hsa-miR-128	CLIP-seq
MIRT2012093	hsa-miR-1283	CLIP-seq
MIRT2012094	hsa-miR-1289	CLIP-seq
MIRT1053204	hsa-miR-129-5p	CLIP-seq
MIRT2012095	hsa-miR-142-5p	CLIP-seq
MIRT1053209	hsa-miR-196a	CLIP-seq
MIRT1053210	hsa-miR-196b	CLIP-seq
MIRT2012096	hsa-miR-19a	CLIP-seq
MIRT2012097	hsa-miR-19b	CLIP-seq
MIRT1053211	hsa-miR-200b	CLIP-seq
MIRT1053212	hsa-miR-200c	CLIP-seq
MIRT2012098	hsa-miR-224	CLIP-seq
MIRT1053215	hsa-miR-27a	CLIP-seq
MIRT1053216	hsa-miR-27b	CLIP-seq
MIRT1053219	hsa-miR-3117-5p	CLIP-seq
MIRT2012099	hsa-miR-3180-5p	CLIP-seq
MIRT2012100	hsa-miR-3198	CLIP-seq
MIRT2012101	hsa-miR-329	CLIP-seq
MIRT2012102	hsa-miR-337-3p	CLIP-seq
MIRT2012103	hsa-miR-340	CLIP-seq
MIRT2012104	hsa-miR-3622a-5p	CLIP-seq
MIRT2012105	hsa-miR-362-3p	CLIP-seq
MIRT1053227	hsa-miR-3927	CLIP-seq
MIRT1053230	hsa-miR-429	CLIP-seq
MIRT2012106	hsa-miR-4294	CLIP-seq
MIRT2012107	hsa-miR-4309	CLIP-seq
MIRT2012108	hsa-miR-432	CLIP-seq
MIRT2012109	hsa-miR-4328	CLIP-seq
MIRT2012110	hsa-miR-4484	CLIP-seq
MIRT1053241	hsa-miR-4713-3p	CLIP-seq
MIRT2012111	hsa-miR-4797-3p	CLIP-seq
MIRT2012112	hsa-miR-4797-5p	CLIP-seq
MIRT2012113	hsa-miR-506	CLIP-seq
MIRT2012114	hsa-miR-517a	CLIP-seq
MIRT2012115	hsa-miR-517b	CLIP-seq
MIRT2012116	hsa-miR-517c	CLIP-seq
MIRT2012117	hsa-miR-518a-5p	CLIP-seq
MIRT2012118	hsa-miR-520a-5p	CLIP-seq
MIRT2012119	hsa-miR-525-5p	CLIP-seq
MIRT2012120	hsa-miR-527	CLIP-seq
MIRT2012121	hsa-miR-548an	CLIP-seq
MIRT2012122	hsa-miR-574-3p	CLIP-seq
MIRT1053258	hsa-miR-599	CLIP-seq
MIRT2012123	hsa-miR-767-3p	CLIP-seq
MIRT2244364	hsa-miR-1252	CLIP-seq
MIRT1053215	hsa-miR-27a	CLIP-seq
MIRT1053216	hsa-miR-27b	CLIP-seq
MIRT2244365	hsa-miR-3942-3p	CLIP-seq
MIRT1053243	hsa-miR-4720-3p	CLIP-seq
MIRT1053244	hsa-miR-4731-3p	CLIP-seq
MIRT1053246	hsa-miR-4801	CLIP-seq
MIRT1053247	hsa-miR-4804-3p	CLIP-seq
MIRT2244366	hsa-miR-499a-5p	CLIP-seq
MIRT2244367	hsa-miR-890	CLIP-seq
MIRT1053204	hsa-miR-129-5p	CLIP-seq
MIRT2465447	hsa-miR-145	CLIP-seq
MIRT2465448	hsa-miR-375	CLIP-seq
MIRT2465449	hsa-miR-561	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	10879542
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	10879542
GO:0001501	Process	Skeletal system development	IEA
GO:0002009	Process	Morphogenesis of an epithelium	IEA
GO:0003016	Process	Respiratory system process	IEA
GO:0003677	Function	DNA binding	IDA	8657138
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IDA	10879542, 16756717
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	15545268, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	15545268
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007389	Process	Pattern specification process	IEA
GO:0007585	Process	Respiratory gaseous exchange by respiratory system	IEA
GO:0009952	Process	Anterior/posterior pattern specification	IBA
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0010628	Process	Positive regulation of gene expression	IDA	10875927
GO:0016477	Process	Cell migration	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IMP	17957028, 23136161
GO:0030324	Process	Lung development	IEA
GO:0030878	Process	Thyroid gland development	IEA
GO:0033599	Process	Regulation of mammary gland epithelial cell proliferation	IEA
GO:0035264	Process	Multicellular organism growth	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IDA	10879542
GO:0045639	Process	Positive regulation of myeloid cell differentiation	IDA	10397719
GO:0045647	Process	Negative regulation of erythrocyte differentiation	IDA	10397719
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	10879542, 16756717
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0048286	Process	Lung alveolus development	IEA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IEA
GO:0048706	Process	Embryonic skeletal system development	IEA
GO:0060435	Process	Bronchiole development	IEA
GO:0060439	Process	Trachea morphogenesis	IEA
GO:0060441	Process	Epithelial tube branching involved in lung morphogenesis	IEA
GO:0060480	Process	Lung goblet cell differentiation	IEA
GO:0060481	Process	Lobar bronchus epithelium development	IEA
GO:0060484	Process	Lung-associated mesenchyme development	IEA
GO:0060535	Process	Trachea cartilage morphogenesis	IEA
GO:0060536	Process	Cartilage morphogenesis	IEA
GO:0060574	Process	Intestinal epithelial cell maturation	IEA
GO:0060638	Process	Mesenchymal-epithelial cell signaling	IEA
GO:0060644	Process	Mammary gland epithelial cell differentiation	IEA
GO:0060749	Process	Mammary gland alveolus development	IEA
GO:0060764	Process	Cell-cell signaling involved in mammary gland development	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
142952	5106	ENSG00000106004

P20719

Protein name

Homeobox protein Hox-A5 (Homeobox protein Hox-1C)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	196 → 252	Homeodomain	Domain

Sequence

MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG
SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKN
SLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWM
RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK
IWFQNRRMKWKKDNKLKSMSMAAAGGAFRP

Sequence length

270

Interactions

View interactions

HOXA5 (homeobox A5)