TTC6 (tetratricopeptide repeat domain 6)

Gene Gene information from NCBI Gene database.
Gene miRNA Other IDs Protein Associated diseases
Entrez ID 319089
Gene name Tetratricopeptide repeat domain 6
Gene symbol TTC6
Synonyms (NCBI Gene)
C14orf25NCRNA00291
Chromosome 14
Chromosome location 14q21.1
miRNA miRNA information provided by mirtarbase database.
1
Gene miRNA Other IDs Protein Associated diseases
Show/Hide all (1)
miRTarBase ID miRNA Experiments Reference
MIRT016743 hsa-miR-335-5p Microarray 18185580
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
620954 19739 ENSG00000139865
Protein Protein information from UniProt database.
Gene miRNA Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86TZ1
Protein name Tetratricopeptide repeat protein 6 (TPR repeat protein 6)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13181 TPR_8 58 → 88 Tetratricopeptide repeat Repeat
PF13432 TPR_16 285 → 346 Family
PF13181 TPR_8 348 → 381 Tetratricopeptide repeat Repeat
PF00515 TPR_1 382 → 415 Tetratricopeptide repeat Repeat
PF00515 TPR_1 450 → 483 Tetratricopeptide repeat Repeat
Sequence 
MMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMC
ALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMT
YKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFL
NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN
PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKA
WNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEF
MGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLM
NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLK
PNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI
Sequence length 520
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
10
Gene miRNA Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (10)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ASTHMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CORONARY ANEURYSM — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LEWY BODY DEMENTIA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (3)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Breast Neoplasms Associate 32321829
★★★★★
★☆☆☆☆
Found in Text Mining only
Ciliopathies Associate 32055034
★★★★★
★☆☆☆☆
Found in Text Mining only
Lung Injury Associate 22986903
★★★★★
★☆☆☆☆
Found in Text Mining only