Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3190
Gene name Gene Name - the full gene name approved by the HGNC.	Heterogeneous nuclear ribonucleoprotein K
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HNRNPK
Synonyms (NCBI Gene) Gene synonyms aliases	AUKS, CSBP, HNRPK, TUNP
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9q21.32
Summary Summary of gene provided in NCBI Entrez Gene.	This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in th

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SNP ID	Visualize variation	Clinical significance	Consequence
rs863223402	->C	Pathogenic	Coding sequence variant, splice donor variant
rs863223403	C>T	Pathogenic-likely-pathogenic	Coding sequence variant, missense variant
rs879255263	->AA	Pathogenic	Coding sequence variant, frameshift variant
rs886041807	->C	Pathogenic	Coding sequence variant, frameshift variant
rs1064794967	C>T	Likely-pathogenic	Coding sequence variant, missense variant
rs1085307831	A>-	Pathogenic	Coding sequence variant, frameshift variant
rs1554698878	G>A	Pathogenic, likely-pathogenic	Coding sequence variant, stop gained
rs1554699378	T>G	Likely-pathogenic	Coding sequence variant, missense variant
rs1554700678	C>T	Uncertain-significance, likely-pathogenic	Coding sequence variant, missense variant
rs1554700718	T>C	Likely-pathogenic	Intron variant
rs1564062144	C>T	Likely-pathogenic	Splice acceptor variant
rs1564063967	A>G	Pathogenic	Coding sequence variant, missense variant
rs1588417800	A>G	Pathogenic	Coding sequence variant, missense variant
rs1588432187	A>C	Likely-pathogenic	Coding sequence variant, missense variant
rs1588434457	AGAA>TGAT	Likely-pathogenic	Coding sequence variant, missense variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004345	hsa-miR-450a-5p	Western blot, Microarray	18230805
MIRT005325	hsa-miR-21-5p	Luciferase reporter assay, qRT-PCR	18829576
MIRT047832	hsa-miR-30c-5p	CLASH	23622248
MIRT047832	hsa-miR-30c-5p	CLASH	23622248
MIRT046389	hsa-miR-15b-5p	CLASH	23622248
MIRT046352	hsa-miR-23b-3p	CLASH	23622248
MIRT045940	hsa-miR-125b-5p	CLASH	23622248
MIRT043787	hsa-miR-328-3p	CLASH	23622248
MIRT042152	hsa-miR-484	CLASH	23622248
MIRT041102	hsa-miR-503-5p	CLASH	23622248
MIRT040216	hsa-miR-615-3p	CLASH	23622248
MIRT040216	hsa-miR-615-3p	CLASH	23622248
MIRT040216	hsa-miR-615-3p	CLASH	23622248
MIRT038583	hsa-miR-106b-3p	CLASH	23622248
MIRT037186	hsa-miR-877-3p	CLASH	23622248
MIRT052770	hsa-miR-1260b	CLASH	23622248
MIRT657332	hsa-miR-649	HITS-CLIP	23824327
MIRT657331	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT657330	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT657329	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT379535	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT379536	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT379537	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT379538	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT379534	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT734547	hsa-miR-148a-3p	Immunoprecipitaion (IP), In situ hybridization, Microarray, Western blotting	33931969
MIRT657332	hsa-miR-649	HITS-CLIP	23824327
MIRT657331	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT657330	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT657329	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT379535	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT379536	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT379537	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT379538	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT379534	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT1051728	hsa-miR-1	CLIP-seq
MIRT1051729	hsa-miR-105	CLIP-seq
MIRT1051730	hsa-miR-1224-3p	CLIP-seq
MIRT1051731	hsa-miR-1249	CLIP-seq
MIRT1051732	hsa-miR-1264	CLIP-seq
MIRT1051733	hsa-miR-1275	CLIP-seq
MIRT1051734	hsa-miR-1276	CLIP-seq
MIRT1051735	hsa-miR-1278	CLIP-seq
MIRT1051736	hsa-miR-1286	CLIP-seq
MIRT1051737	hsa-miR-129-5p	CLIP-seq
MIRT1051738	hsa-miR-181a	CLIP-seq
MIRT1051739	hsa-miR-181b	CLIP-seq
MIRT1051740	hsa-miR-181c	CLIP-seq
MIRT1051741	hsa-miR-181d	CLIP-seq
MIRT1051742	hsa-miR-205	CLIP-seq
MIRT1051743	hsa-miR-206	CLIP-seq
MIRT1051744	hsa-miR-219-2-3p	CLIP-seq
MIRT1051745	hsa-miR-2278	CLIP-seq
MIRT1051746	hsa-miR-2467-3p	CLIP-seq
MIRT1051747	hsa-miR-2681	CLIP-seq
MIRT1051748	hsa-miR-28-5p	CLIP-seq
MIRT1051749	hsa-miR-2964a-3p	CLIP-seq
MIRT1051750	hsa-miR-298	CLIP-seq
MIRT1051751	hsa-miR-3117-5p	CLIP-seq
MIRT1051752	hsa-miR-3119	CLIP-seq
MIRT1051753	hsa-miR-3120-3p	CLIP-seq
MIRT1051754	hsa-miR-3125	CLIP-seq
MIRT1051755	hsa-miR-3129-3p	CLIP-seq
MIRT1051756	hsa-miR-3130-3p	CLIP-seq
MIRT1051757	hsa-miR-3139	CLIP-seq
MIRT1051758	hsa-miR-3157-5p	CLIP-seq
MIRT1051759	hsa-miR-3160-3p	CLIP-seq
MIRT1051760	hsa-miR-3168	CLIP-seq
MIRT1051761	hsa-miR-3194-3p	CLIP-seq
MIRT1051762	hsa-miR-3591-5p	CLIP-seq
MIRT1051763	hsa-miR-3617	CLIP-seq
MIRT1051764	hsa-miR-3647-3p	CLIP-seq
MIRT1051765	hsa-miR-3662	CLIP-seq
MIRT1051766	hsa-miR-3671	CLIP-seq
MIRT1051767	hsa-miR-3679-3p	CLIP-seq
MIRT1051768	hsa-miR-3680	CLIP-seq
MIRT1051769	hsa-miR-3685	CLIP-seq
MIRT1051770	hsa-miR-376c	CLIP-seq
MIRT1051771	hsa-miR-384	CLIP-seq
MIRT1051772	hsa-miR-3916	CLIP-seq
MIRT1051773	hsa-miR-3919	CLIP-seq
MIRT1051774	hsa-miR-3934	CLIP-seq
MIRT1051775	hsa-miR-3940-5p	CLIP-seq
MIRT1051776	hsa-miR-409-3p	CLIP-seq
MIRT1051777	hsa-miR-412	CLIP-seq
MIRT1051778	hsa-miR-4255	CLIP-seq
MIRT1051779	hsa-miR-4260	CLIP-seq
MIRT1051780	hsa-miR-4262	CLIP-seq
MIRT1051781	hsa-miR-4277	CLIP-seq
MIRT1051782	hsa-miR-4282	CLIP-seq
MIRT1051783	hsa-miR-4286	CLIP-seq
MIRT1051784	hsa-miR-4291	CLIP-seq
MIRT1051785	hsa-miR-4310	CLIP-seq
MIRT1051786	hsa-miR-4325	CLIP-seq
MIRT1051787	hsa-miR-4452	CLIP-seq
MIRT1051788	hsa-miR-4455	CLIP-seq
MIRT1051789	hsa-miR-4480	CLIP-seq
MIRT1051790	hsa-miR-4491	CLIP-seq
MIRT1051791	hsa-miR-4507	CLIP-seq
MIRT1051792	hsa-miR-450b-5p	CLIP-seq
MIRT1051793	hsa-miR-4539	CLIP-seq
MIRT1051794	hsa-miR-4639-3p	CLIP-seq
MIRT1051795	hsa-miR-4645-3p	CLIP-seq
MIRT1051796	hsa-miR-4651	CLIP-seq
MIRT1051797	hsa-miR-4657	CLIP-seq
MIRT1051798	hsa-miR-4665-5p	CLIP-seq
MIRT1051799	hsa-miR-4666-5p	CLIP-seq
MIRT1051800	hsa-miR-4691-3p	CLIP-seq
MIRT1051801	hsa-miR-4698	CLIP-seq
MIRT1051802	hsa-miR-4704-5p	CLIP-seq
MIRT1051803	hsa-miR-4705	CLIP-seq
MIRT1051804	hsa-miR-4708-5p	CLIP-seq
MIRT1051805	hsa-miR-4722-5p	CLIP-seq
MIRT1051806	hsa-miR-4731-3p	CLIP-seq
MIRT1051807	hsa-miR-4755-3p	CLIP-seq
MIRT1051808	hsa-miR-4762-5p	CLIP-seq
MIRT1051809	hsa-miR-4781-3p	CLIP-seq
MIRT1051810	hsa-miR-4793-3p	CLIP-seq
MIRT1051811	hsa-miR-4796-5p	CLIP-seq
MIRT1051812	hsa-miR-4801	CLIP-seq
MIRT1051813	hsa-miR-4802-3p	CLIP-seq
MIRT1051814	hsa-miR-4803	CLIP-seq
MIRT1051815	hsa-miR-507	CLIP-seq
MIRT1051816	hsa-miR-5095	CLIP-seq
MIRT1051817	hsa-miR-513a-3p	CLIP-seq
MIRT1051818	hsa-miR-513b	CLIP-seq
MIRT1051819	hsa-miR-520d-5p	CLIP-seq
MIRT1051820	hsa-miR-522	CLIP-seq
MIRT1051821	hsa-miR-524-5p	CLIP-seq
MIRT1051822	hsa-miR-539	CLIP-seq
MIRT1051823	hsa-miR-544	CLIP-seq
MIRT1051824	hsa-miR-545	CLIP-seq
MIRT1051825	hsa-miR-548c-3p	CLIP-seq
MIRT1051826	hsa-miR-552	CLIP-seq
MIRT1051827	hsa-miR-557	CLIP-seq
MIRT1051828	hsa-miR-577	CLIP-seq
MIRT1051829	hsa-miR-600	CLIP-seq
MIRT1051830	hsa-miR-607	CLIP-seq
MIRT1051831	hsa-miR-608	CLIP-seq
MIRT1051832	hsa-miR-609	CLIP-seq
MIRT1051833	hsa-miR-613	CLIP-seq
MIRT1051834	hsa-miR-625	CLIP-seq
MIRT1051835	hsa-miR-641	CLIP-seq
MIRT1051836	hsa-miR-708	CLIP-seq
MIRT1051837	hsa-miR-873	CLIP-seq
MIRT1051838	hsa-miR-943	CLIP-seq
MIRT1051728	hsa-miR-1	CLIP-seq
MIRT1051729	hsa-miR-105	CLIP-seq
MIRT2011765	hsa-miR-10a	CLIP-seq
MIRT2011766	hsa-miR-10b	CLIP-seq
MIRT1051731	hsa-miR-1249	CLIP-seq
MIRT1051737	hsa-miR-129-5p	CLIP-seq
MIRT2011767	hsa-miR-1305	CLIP-seq
MIRT1051738	hsa-miR-181a	CLIP-seq
MIRT1051739	hsa-miR-181b	CLIP-seq
MIRT1051740	hsa-miR-181c	CLIP-seq
MIRT1051741	hsa-miR-181d	CLIP-seq
MIRT1051743	hsa-miR-206	CLIP-seq
MIRT1051746	hsa-miR-2467-3p	CLIP-seq
MIRT1051748	hsa-miR-28-5p	CLIP-seq
MIRT1051750	hsa-miR-298	CLIP-seq
MIRT2011768	hsa-miR-3065-5p	CLIP-seq
MIRT1051752	hsa-miR-3119	CLIP-seq
MIRT1051754	hsa-miR-3125	CLIP-seq
MIRT1051756	hsa-miR-3130-3p	CLIP-seq
MIRT2011769	hsa-miR-3138	CLIP-seq
MIRT1051757	hsa-miR-3139	CLIP-seq
MIRT2011770	hsa-miR-3152-5p	CLIP-seq
MIRT1051759	hsa-miR-3160-3p	CLIP-seq
MIRT1051760	hsa-miR-3168	CLIP-seq
MIRT1051761	hsa-miR-3194-3p	CLIP-seq
MIRT2011771	hsa-miR-323-3p	CLIP-seq
MIRT1051764	hsa-miR-3647-3p	CLIP-seq
MIRT2011772	hsa-miR-3658	CLIP-seq
MIRT1051766	hsa-miR-3671	CLIP-seq
MIRT1051767	hsa-miR-3679-3p	CLIP-seq
MIRT1051772	hsa-miR-3916	CLIP-seq
MIRT2011773	hsa-miR-3920	CLIP-seq
MIRT2011774	hsa-miR-3928	CLIP-seq
MIRT1051774	hsa-miR-3934	CLIP-seq
MIRT1051776	hsa-miR-409-3p	CLIP-seq
MIRT1051777	hsa-miR-412	CLIP-seq
MIRT2011775	hsa-miR-421	CLIP-seq
MIRT1051780	hsa-miR-4262	CLIP-seq
MIRT1051782	hsa-miR-4282	CLIP-seq
MIRT2011776	hsa-miR-4299	CLIP-seq
MIRT1051786	hsa-miR-4325	CLIP-seq
MIRT2011777	hsa-miR-4456	CLIP-seq
MIRT1051789	hsa-miR-4480	CLIP-seq
MIRT2011778	hsa-miR-4490	CLIP-seq
MIRT1051790	hsa-miR-4491	CLIP-seq
MIRT1051792	hsa-miR-450b-5p	CLIP-seq
MIRT1051793	hsa-miR-4539	CLIP-seq
MIRT1051794	hsa-miR-4639-3p	CLIP-seq
MIRT1051797	hsa-miR-4657	CLIP-seq
MIRT2011779	hsa-miR-4668-3p	CLIP-seq
MIRT1051801	hsa-miR-4698	CLIP-seq
MIRT1051803	hsa-miR-4705	CLIP-seq
MIRT1051804	hsa-miR-4708-5p	CLIP-seq
MIRT1051807	hsa-miR-4755-3p	CLIP-seq
MIRT2011780	hsa-miR-4762-3p	CLIP-seq
MIRT1051808	hsa-miR-4762-5p	CLIP-seq
MIRT2011781	hsa-miR-4774-3p	CLIP-seq
MIRT2011782	hsa-miR-4774-5p	CLIP-seq
MIRT2011783	hsa-miR-4778-5p	CLIP-seq
MIRT1051809	hsa-miR-4781-3p	CLIP-seq
MIRT1051810	hsa-miR-4793-3p	CLIP-seq
MIRT2011784	hsa-miR-4800-5p	CLIP-seq
MIRT1051815	hsa-miR-507	CLIP-seq
MIRT1051816	hsa-miR-5095	CLIP-seq
MIRT1051817	hsa-miR-513a-3p	CLIP-seq
MIRT1051818	hsa-miR-513b	CLIP-seq
MIRT1051819	hsa-miR-520d-5p	CLIP-seq
MIRT1051821	hsa-miR-524-5p	CLIP-seq
MIRT1051822	hsa-miR-539	CLIP-seq
MIRT1051823	hsa-miR-544	CLIP-seq
MIRT2011785	hsa-miR-548a-3p	CLIP-seq
MIRT2011786	hsa-miR-548e	CLIP-seq
MIRT2011787	hsa-miR-548f	CLIP-seq
MIRT2011788	hsa-miR-548q	CLIP-seq
MIRT1051826	hsa-miR-552	CLIP-seq
MIRT1051827	hsa-miR-557	CLIP-seq
MIRT1051830	hsa-miR-607	CLIP-seq
MIRT1051833	hsa-miR-613	CLIP-seq
MIRT1051836	hsa-miR-708	CLIP-seq
MIRT1051728	hsa-miR-1	CLIP-seq
MIRT1051729	hsa-miR-105	CLIP-seq
MIRT2011765	hsa-miR-10a	CLIP-seq
MIRT2011766	hsa-miR-10b	CLIP-seq
MIRT1051730	hsa-miR-1224-3p	CLIP-seq
MIRT2244039	hsa-miR-1238	CLIP-seq
MIRT1051731	hsa-miR-1249	CLIP-seq
MIRT2244040	hsa-miR-1260	CLIP-seq
MIRT1051732	hsa-miR-1264	CLIP-seq
MIRT1051734	hsa-miR-1276	CLIP-seq
MIRT2244041	hsa-miR-1280	CLIP-seq
MIRT1051737	hsa-miR-129-5p	CLIP-seq
MIRT1051738	hsa-miR-181a	CLIP-seq
MIRT1051739	hsa-miR-181b	CLIP-seq
MIRT1051740	hsa-miR-181c	CLIP-seq
MIRT1051741	hsa-miR-181d	CLIP-seq
MIRT1051743	hsa-miR-206	CLIP-seq
MIRT1051745	hsa-miR-2278	CLIP-seq
MIRT1051746	hsa-miR-2467-3p	CLIP-seq
MIRT1051750	hsa-miR-298	CLIP-seq
MIRT1051752	hsa-miR-3119	CLIP-seq
MIRT1051754	hsa-miR-3125	CLIP-seq
MIRT1051756	hsa-miR-3130-3p	CLIP-seq
MIRT2011769	hsa-miR-3138	CLIP-seq
MIRT2011770	hsa-miR-3152-5p	CLIP-seq
MIRT1051761	hsa-miR-3194-3p	CLIP-seq
MIRT2011771	hsa-miR-323-3p	CLIP-seq
MIRT2244042	hsa-miR-330-3p	CLIP-seq
MIRT2244043	hsa-miR-339-5p	CLIP-seq
MIRT1051767	hsa-miR-3679-3p	CLIP-seq
MIRT1051769	hsa-miR-3685	CLIP-seq
MIRT1051771	hsa-miR-384	CLIP-seq
MIRT1051772	hsa-miR-3916	CLIP-seq
MIRT1051773	hsa-miR-3919	CLIP-seq
MIRT2244044	hsa-miR-3924	CLIP-seq
MIRT1051776	hsa-miR-409-3p	CLIP-seq
MIRT1051780	hsa-miR-4262	CLIP-seq
MIRT1051782	hsa-miR-4282	CLIP-seq
MIRT1051786	hsa-miR-4325	CLIP-seq
MIRT1051789	hsa-miR-4480	CLIP-seq
MIRT2011778	hsa-miR-4490	CLIP-seq
MIRT1051790	hsa-miR-4491	CLIP-seq
MIRT1051792	hsa-miR-450b-5p	CLIP-seq
MIRT1051793	hsa-miR-4539	CLIP-seq
MIRT1051795	hsa-miR-4645-3p	CLIP-seq
MIRT1051797	hsa-miR-4657	CLIP-seq
MIRT2244045	hsa-miR-4691-5p	CLIP-seq
MIRT1051801	hsa-miR-4698	CLIP-seq
MIRT1051803	hsa-miR-4705	CLIP-seq
MIRT1051804	hsa-miR-4708-5p	CLIP-seq
MIRT1051806	hsa-miR-4731-3p	CLIP-seq
MIRT1051807	hsa-miR-4755-3p	CLIP-seq
MIRT2244046	hsa-miR-4761-5p	CLIP-seq
MIRT2011781	hsa-miR-4774-3p	CLIP-seq
MIRT2011782	hsa-miR-4774-5p	CLIP-seq
MIRT1051809	hsa-miR-4781-3p	CLIP-seq
MIRT1051810	hsa-miR-4793-3p	CLIP-seq
MIRT1051811	hsa-miR-4796-5p	CLIP-seq
MIRT2011784	hsa-miR-4800-5p	CLIP-seq
MIRT1051812	hsa-miR-4801	CLIP-seq
MIRT1051815	hsa-miR-507	CLIP-seq
MIRT1051817	hsa-miR-513a-3p	CLIP-seq
MIRT1051820	hsa-miR-522	CLIP-seq
MIRT1051822	hsa-miR-539	CLIP-seq
MIRT1051823	hsa-miR-544	CLIP-seq
MIRT1051827	hsa-miR-557	CLIP-seq
MIRT2244047	hsa-miR-582-5p	CLIP-seq
MIRT1051830	hsa-miR-607	CLIP-seq
MIRT1051833	hsa-miR-613	CLIP-seq
MIRT2011765	hsa-miR-10a	CLIP-seq
MIRT2011766	hsa-miR-10b	CLIP-seq
MIRT2389092	hsa-miR-3163	CLIP-seq
MIRT1051822	hsa-miR-539	CLIP-seq
MIRT1051732	hsa-miR-1264	CLIP-seq
MIRT1051735	hsa-miR-1278	CLIP-seq
MIRT1051795	hsa-miR-4645-3p	CLIP-seq
MIRT1051811	hsa-miR-4796-5p	CLIP-seq
MIRT1051822	hsa-miR-539	CLIP-seq
MIRT2429683	hsa-miR-885-5p	CLIP-seq
MIRT2429684	hsa-miR-888	CLIP-seq
MIRT2011765	hsa-miR-10a	CLIP-seq
MIRT2011766	hsa-miR-10b	CLIP-seq
MIRT1051730	hsa-miR-1224-3p	CLIP-seq
MIRT2547069	hsa-miR-1226	CLIP-seq
MIRT2244039	hsa-miR-1238	CLIP-seq
MIRT1051731	hsa-miR-1249	CLIP-seq
MIRT2244040	hsa-miR-1260	CLIP-seq
MIRT2547070	hsa-miR-1272	CLIP-seq
MIRT2244041	hsa-miR-1280	CLIP-seq
MIRT1051737	hsa-miR-129-5p	CLIP-seq
MIRT2547071	hsa-miR-1322	CLIP-seq
MIRT2547072	hsa-miR-21	CLIP-seq
MIRT2547073	hsa-miR-2355-5p	CLIP-seq
MIRT2547074	hsa-miR-3134	CLIP-seq
MIRT2011770	hsa-miR-3152-5p	CLIP-seq
MIRT2389092	hsa-miR-3163	CLIP-seq
MIRT2011771	hsa-miR-323-3p	CLIP-seq
MIRT2244042	hsa-miR-330-3p	CLIP-seq
MIRT2244043	hsa-miR-339-5p	CLIP-seq
MIRT2547075	hsa-miR-3613-3p	CLIP-seq
MIRT1051767	hsa-miR-3679-3p	CLIP-seq
MIRT2244044	hsa-miR-3924	CLIP-seq
MIRT2547076	hsa-miR-3942-5p	CLIP-seq
MIRT1051782	hsa-miR-4282	CLIP-seq
MIRT1051789	hsa-miR-4480	CLIP-seq
MIRT1051792	hsa-miR-450b-5p	CLIP-seq
MIRT2547077	hsa-miR-4534	CLIP-seq
MIRT2547078	hsa-miR-4659a-3p	CLIP-seq
MIRT2547079	hsa-miR-4659b-3p	CLIP-seq
MIRT1051799	hsa-miR-4666-5p	CLIP-seq
MIRT2011779	hsa-miR-4668-3p	CLIP-seq
MIRT2547080	hsa-miR-4688	CLIP-seq
MIRT2244045	hsa-miR-4691-5p	CLIP-seq
MIRT1051801	hsa-miR-4698	CLIP-seq
MIRT2547081	hsa-miR-4703-5p	CLIP-seq
MIRT2547082	hsa-miR-4733-3p	CLIP-seq
MIRT2244046	hsa-miR-4761-5p	CLIP-seq
MIRT2011781	hsa-miR-4774-3p	CLIP-seq
MIRT2547083	hsa-miR-4776-3p	CLIP-seq
MIRT2547084	hsa-miR-4795-3p	CLIP-seq
MIRT1051813	hsa-miR-4802-3p	CLIP-seq
MIRT2547085	hsa-miR-495	CLIP-seq
MIRT1051815	hsa-miR-507	CLIP-seq
MIRT1051817	hsa-miR-513a-3p	CLIP-seq
MIRT1051818	hsa-miR-513b	CLIP-seq
MIRT2547086	hsa-miR-518a-5p	CLIP-seq
MIRT2547087	hsa-miR-527	CLIP-seq
MIRT1051825	hsa-miR-548c-3p	CLIP-seq
MIRT2547088	hsa-miR-548n	CLIP-seq
MIRT1051827	hsa-miR-557	CLIP-seq
MIRT2244047	hsa-miR-582-5p	CLIP-seq
MIRT2547089	hsa-miR-590-5p	CLIP-seq
MIRT2547090	hsa-miR-605	CLIP-seq
MIRT1051830	hsa-miR-607	CLIP-seq
MIRT2547091	hsa-miR-617	CLIP-seq
MIRT1051834	hsa-miR-625	CLIP-seq
MIRT2547092	hsa-miR-653	CLIP-seq
MIRT2011765	hsa-miR-10a	CLIP-seq
MIRT2011766	hsa-miR-10b	CLIP-seq
MIRT1051730	hsa-miR-1224-3p	CLIP-seq
MIRT2547069	hsa-miR-1226	CLIP-seq
MIRT2244039	hsa-miR-1238	CLIP-seq
MIRT1051731	hsa-miR-1249	CLIP-seq
MIRT2244040	hsa-miR-1260	CLIP-seq
MIRT2547070	hsa-miR-1272	CLIP-seq
MIRT1051735	hsa-miR-1278	CLIP-seq
MIRT2244041	hsa-miR-1280	CLIP-seq
MIRT1051737	hsa-miR-129-5p	CLIP-seq
MIRT2547071	hsa-miR-1322	CLIP-seq
MIRT2547072	hsa-miR-21	CLIP-seq
MIRT2547073	hsa-miR-2355-5p	CLIP-seq
MIRT2547074	hsa-miR-3134	CLIP-seq
MIRT2011769	hsa-miR-3138	CLIP-seq
MIRT1051760	hsa-miR-3168	CLIP-seq
MIRT2011771	hsa-miR-323-3p	CLIP-seq
MIRT2244042	hsa-miR-330-3p	CLIP-seq
MIRT2244043	hsa-miR-339-5p	CLIP-seq
MIRT2547075	hsa-miR-3613-3p	CLIP-seq
MIRT1051764	hsa-miR-3647-3p	CLIP-seq
MIRT1051767	hsa-miR-3679-3p	CLIP-seq
MIRT1051770	hsa-miR-376c	CLIP-seq
MIRT2244044	hsa-miR-3924	CLIP-seq
MIRT2547076	hsa-miR-3942-5p	CLIP-seq
MIRT1051777	hsa-miR-412	CLIP-seq
MIRT1051782	hsa-miR-4282	CLIP-seq
MIRT1051783	hsa-miR-4286	CLIP-seq
MIRT1051789	hsa-miR-4480	CLIP-seq
MIRT2011778	hsa-miR-4490	CLIP-seq
MIRT1051790	hsa-miR-4491	CLIP-seq
MIRT1051792	hsa-miR-450b-5p	CLIP-seq
MIRT2547077	hsa-miR-4534	CLIP-seq
MIRT1051797	hsa-miR-4657	CLIP-seq
MIRT2547078	hsa-miR-4659a-3p	CLIP-seq
MIRT2547079	hsa-miR-4659b-3p	CLIP-seq
MIRT1051799	hsa-miR-4666-5p	CLIP-seq
MIRT2011779	hsa-miR-4668-3p	CLIP-seq
MIRT2547080	hsa-miR-4688	CLIP-seq
MIRT2244045	hsa-miR-4691-5p	CLIP-seq
MIRT1051801	hsa-miR-4698	CLIP-seq
MIRT2547081	hsa-miR-4703-5p	CLIP-seq
MIRT2547082	hsa-miR-4733-3p	CLIP-seq
MIRT1051807	hsa-miR-4755-3p	CLIP-seq
MIRT2244046	hsa-miR-4761-5p	CLIP-seq
MIRT2011782	hsa-miR-4774-5p	CLIP-seq
MIRT2547083	hsa-miR-4776-3p	CLIP-seq
MIRT2547084	hsa-miR-4795-3p	CLIP-seq
MIRT2011784	hsa-miR-4800-5p	CLIP-seq
MIRT1051813	hsa-miR-4802-3p	CLIP-seq
MIRT1051814	hsa-miR-4803	CLIP-seq
MIRT2547085	hsa-miR-495	CLIP-seq
MIRT1051815	hsa-miR-507	CLIP-seq
MIRT1051817	hsa-miR-513a-3p	CLIP-seq
MIRT1051818	hsa-miR-513b	CLIP-seq
MIRT2547086	hsa-miR-518a-5p	CLIP-seq
MIRT2547087	hsa-miR-527	CLIP-seq
MIRT1051825	hsa-miR-548c-3p	CLIP-seq
MIRT2547088	hsa-miR-548n	CLIP-seq
MIRT1051827	hsa-miR-557	CLIP-seq
MIRT2244047	hsa-miR-582-5p	CLIP-seq
MIRT2547089	hsa-miR-590-5p	CLIP-seq
MIRT2547090	hsa-miR-605	CLIP-seq
MIRT1051830	hsa-miR-607	CLIP-seq
MIRT2547091	hsa-miR-617	CLIP-seq
MIRT1051834	hsa-miR-625	CLIP-seq
MIRT2547092	hsa-miR-653	CLIP-seq
MIRT2429683	hsa-miR-885-5p	CLIP-seq
MIRT2429684	hsa-miR-888	CLIP-seq

Show/Hide all(51)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IC	11991638
GO:0000785	Component	Chromatin	IDA	20371611, 33174841
GO:0002102	Component	Podosome	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003723	Function	RNA binding	TAS	8107114
GO:0003729	Function	MRNA binding	IBA
GO:0005515	Function	Protein binding	IPI	9651361, 10332027, 10749975, 12183465, 12577067, 16189514, 16713569, 17178840, 18457437, 18775702, 19101556, 19174163, 19249676, 20085233, 20936779, 21044950, 21516116, 21821029, 21988832, 22365833, 23092970, 23825951, 24965446, 25416956, 25678563, 25910212, 26496610, 26871637, 2710
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	33174841
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005681	Component	Spliceosomal complex	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	33174841
GO:0005737	Component	Cytoplasm	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006396	Process	RNA processing	TAS	8107114
GO:0006397	Process	MRNA processing	IEA
GO:0007165	Process	Signal transduction	TAS	16130169
GO:0008380	Process	RNA splicing	IEA
GO:0010494	Component	Cytoplasmic stress granule	IEA
GO:0010494	Component	Cytoplasmic stress granule	ISS
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0019904	Function	Protein domain specific binding	IPI	10749975
GO:0031048	Process	Regulatory ncRNA-mediated heterochromatin formation	IMP	25843628
GO:0042802	Function	Identical protein binding	IPI	16004877, 16189514, 22365833, 25416956, 29892012, 32296183, 32499643
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	20548952
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	33174841
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0048024	Process	Regulation of mRNA splicing, via spliceosome	IBA
GO:0048025	Process	Negative regulation of mRNA splicing, via spliceosome	IEA
GO:0051253	Process	Negative regulation of RNA metabolic process	IEA
GO:0060816	Process	Random inactivation of X chromosome	IDA	25843628
GO:0070062	Component	Extracellular exosome	HDA	20458337, 23533145
GO:0070161	Component	Anchoring junction	IEA
GO:0071013	Component	Catalytic step 2 spliceosome	IDA	11991638
GO:1902165	Process	Regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IEA
GO:1905581	Process	Positive regulation of low-density lipoprotein particle clearance	IMP	20371611
GO:1990904	Component	Ribonucleoprotein complex	IDA	33174841
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
600712	5044	ENSG00000165119

Protein

UniProt ID

P61978

Protein name

Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)

Protein function

One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded

PDB

1J5K , 1KHM , 1ZZI , 1ZZJ , 1ZZK , 7CRE , 7CRU , 7RJK , 7RJO

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08067	ROKNT	1 → 43	ROKNT (NUC014) domain	Domain
PF00013	KH_1	44 → 105	KH domain	Domain
PF00013	KH_1	146 → 211	KH domain	Domain
PF00013	KH_1	389 → 453	KH domain	Domain

Sequence

METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF

Sequence length

463

Interactions

View interactions

	KEGG		Reactome
	Spliceosome Viral carcinogenesis MicroRNAs in cancer		SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA HCMV Late Events

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
AU-KLINE Syndrome	au-kline syndrome	rs1554698681, rs1554698878, rs1554700718, rs1564062144, rs863223402, rs1564063967, rs863223403, rs1588434457, rs879255263, rs1588412390, rs886041807, rs1588432187, rs1554698658, rs1588417800, rs1554698213, rs1554698470 View all (1 more)	N/A

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Dysmorphism	neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-hip dysplasia syndrome	N/A	N/A	GenCC

Show/Hide Text Mining Associations (62)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	30272263
Adenocarcinoma of Lung	Associate	26972480, 31187136, 35091468
Alzheimer's disease without Neurofibrillary tangles	Associate	34274995
Amyotrophic Lateral Sclerosis	Associate	36261283
Anemia Diamond Blackfan	Associate	33660773
Breast Neoplasms	Associate	30468106, 33806648, 40604083
Burkitt Lymphoma	Associate	26317903
Calcinosis Cutis	Associate	26713736
Capillary Malformation Arteriovenous Malformation	Associate	26173930
Carcinogenesis	Associate	16953238, 19609950, 20499280, 25645922, 26713736, 27862976, 31187136, 35866661, 36209503, 36681772, 36700980
Carcinoma Hepatocellular	Associate	22760167, 31429522, 33891563, 34299096
Carcinoma Non Small Cell Lung	Associate	31187136, 31492158
Carcinoma Renal Cell	Associate	26713736
Cell Transformation Neoplastic	Associate	36209503
Cholangiocarcinoma	Associate	30444036
Colonic Neoplasms	Associate	16404425
Colorectal Neoplasms	Stimulate	16953238
Colorectal Neoplasms	Associate	30272263, 32901844
Connective Tissue Diseases	Associate	26954065
Developmental Disabilities	Associate	37407733
Drug Related Side Effects and Adverse Reactions	Associate	22582387
Fibrosis	Associate	22760167
Frontotemporal Lobar Degeneration	Associate	34274995
Glioblastoma	Associate	37460467
Glioma	Associate	26305187
Inflammation	Associate	35866661
Influenza Human	Associate	29921878
Intellectual Disability	Associate	26173930
Kabuki syndrome	Associate	26954065, 36130591
Keratitis Dendritic	Associate	36261283
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	16293596
Leukemia Myeloid Acute	Associate	27155326
Liver Cirrhosis	Associate	22760167
Lung Neoplasms	Associate	12871776, 31492158, 36681772
Melanoma	Associate	20499280, 26136337, 30272263, 32901844
Musculoskeletal Abnormalities	Associate	26173930
Mycosis Fungoides	Associate	30144205
Myelodysplastic Syndromes	Associate	30249787
Nasopharyngeal Carcinoma	Associate	24885469
Neoplasm Invasiveness	Associate	26713736
Neoplasm Metastasis	Associate	24885469, 26713736, 30444036, 36209503
Neoplasms	Associate	14562022, 16404425, 22582387, 25104022, 26713736, 26972480, 27862976, 28423633, 28708135, 30272263, 31110205, 32901844, 33731671, 34274995, 34575922 View all (5 more)
Neoplasms	Stimulate	16953238, 31492158
Neoplasms	Inhibit	19609950
Neuralgia	Associate	37877615
Osteoarthritis	Associate	24148886
Osteosarcoma	Associate	34575922
Pancreatic Neoplasms	Stimulate	19609950
Pancreatic Neoplasms	Associate	20499280
Periventricular Nodular Heterotopia	Associate	26954065
Precancerous Conditions	Associate	36700980
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	35038545
Prostatic Neoplasms	Associate	19401687, 29966326, 31221168
Prostatic Neoplasms Castration Resistant	Associate	29966326, 31221168
Spinocerebellar Ataxia 10	Associate	20548952
Squamous Cell Carcinoma of Head and Neck	Associate	19015635, 32901844
Systemic Inflammatory Response Syndrome	Associate	35866661
Triple Negative Breast Neoplasms	Associate	37592256, 38238853
Urethral Neoplasms	Associate	29480994
Urinary Bladder Neoplasms	Associate	27862976, 29480994
Uterine Cervical Neoplasms	Associate	35866661, 36700980
Uterine Cervicitis	Associate	36700980

HNRNPK (heterogeneous nuclear ribonucleoprotein K)