Gene Gene information from NCBI Gene database.
Entrez ID 317781
Gene name DEAD-box helicase 51
Gene symbol DDX51
Synonyms (NCBI Gene)
-
Chromosome 12
Chromosome location 12q24.33
miRNA miRNA information provided by mirtarbase database.
471
miRTarBase ID miRNA Experiments Reference
MIRT022177 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT618268 hsa-miR-6819-3p HITS-CLIP 23824327
MIRT618267 hsa-miR-6877-3p HITS-CLIP 23824327
MIRT618266 hsa-miR-8062 HITS-CLIP 23824327
MIRT618265 hsa-miR-4722-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IEA
GO:0003724 Function RNA helicase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N8A6
Protein name ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51)
Protein function ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00270 DEAD 222 441 DEAD/DEAH box helicase Domain
PF00271 Helicase_C 490 600 Helicase conserved C-terminal domain Family
Sequence
MALFYVARYPGPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAST
EPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAP
GEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPR
WLAEPNCVRRNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGF
LVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKV
FNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGF
SLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCC
PQMPLQKLLFSATLTQNPEKL
QQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLT
HHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG
PGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAG

KTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEE
RKQRAA
Sequence length 666
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Gastric cancer Uncertain significance rs200793638 RCV005928933