HMMR (hyaluronan mediated motility receptor)

Gene

• Entrez ID: 3161
• Gene name: Hyaluronan mediated motility receptor
• Gene symbol: HMMR
• Synonyms (NCBI Gene): CD168, IHABP, RHAMM
• Chromosome: 5
• Chromosome location: 5q34
• Summary: The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spli

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024628	hsa-miR-215-5p	Microarray	19074876
MIRT026177	hsa-miR-192-5p	Microarray	19074876
MIRT027466	hsa-miR-98-5p	Microarray	19088304
MIRT044370	hsa-miR-106b-5p	CLASH	23622248
MIRT038799	hsa-miR-93-3p	CLASH	23622248
MIRT733825	hsa-miR-411-5p	Luciferase reporter assay, qRT-PCR, Western blotting	32782498
MIRT1050086	hsa-miR-4484	CLIP-seq
MIRT1050087	hsa-miR-4753-5p	CLIP-seq
MIRT1050088	hsa-miR-548an	CLIP-seq
MIRT1050089	hsa-miR-4792	CLIP-seq
MIRT1050090	hsa-miR-548m	CLIP-seq
MIRT1050091	hsa-miR-23a	CLIP-seq
MIRT1050092	hsa-miR-23b	CLIP-seq
MIRT1050093	hsa-miR-23c	CLIP-seq
MIRT1050094	hsa-miR-3120-3p	CLIP-seq
MIRT1050095	hsa-miR-3121-3p	CLIP-seq
MIRT1050096	hsa-miR-34a	CLIP-seq
MIRT1050097	hsa-miR-34c-5p	CLIP-seq
MIRT1050098	hsa-miR-3607-3p	CLIP-seq
MIRT1050099	hsa-miR-3671	CLIP-seq
MIRT1050100	hsa-miR-369-3p	CLIP-seq
MIRT1050101	hsa-miR-374a	CLIP-seq
MIRT1050102	hsa-miR-374b	CLIP-seq
MIRT1050103	hsa-miR-3920	CLIP-seq
MIRT1050104	hsa-miR-3976	CLIP-seq
MIRT1050105	hsa-miR-4326	CLIP-seq
MIRT1050106	hsa-miR-4477a	CLIP-seq
MIRT1050107	hsa-miR-4477b	CLIP-seq
MIRT1050108	hsa-miR-449a	CLIP-seq
MIRT1050109	hsa-miR-449b	CLIP-seq
MIRT1050110	hsa-miR-4670-3p	CLIP-seq
MIRT1050111	hsa-miR-548c-3p	CLIP-seq
MIRT1050112	hsa-miR-660	CLIP-seq
MIRT1050113	hsa-miR-9	CLIP-seq
MIRT1050114	hsa-miR-944	CLIP-seq
MIRT1050115	hsa-miR-1185	CLIP-seq
MIRT1050091	hsa-miR-23a	CLIP-seq
MIRT1050092	hsa-miR-23b	CLIP-seq
MIRT1050093	hsa-miR-23c	CLIP-seq
MIRT1050116	hsa-miR-3163	CLIP-seq
MIRT1050117	hsa-miR-3185	CLIP-seq
MIRT1050118	hsa-miR-340	CLIP-seq
MIRT1050096	hsa-miR-34a	CLIP-seq
MIRT1050097	hsa-miR-34c-5p	CLIP-seq
MIRT1050099	hsa-miR-3671	CLIP-seq
MIRT1050119	hsa-miR-3679-5p	CLIP-seq
MIRT1050120	hsa-miR-3942-3p	CLIP-seq
MIRT1050105	hsa-miR-4326	CLIP-seq
MIRT1050121	hsa-miR-4459	CLIP-seq
MIRT1050107	hsa-miR-4477b	CLIP-seq
MIRT1050108	hsa-miR-449a	CLIP-seq
MIRT1050109	hsa-miR-449b	CLIP-seq
MIRT1050122	hsa-miR-4528	CLIP-seq
MIRT1050123	hsa-miR-4667-5p	CLIP-seq
MIRT1050124	hsa-miR-4700-5p	CLIP-seq
MIRT1050125	hsa-miR-4773	CLIP-seq
MIRT1050126	hsa-miR-637	CLIP-seq
MIRT1050112	hsa-miR-660	CLIP-seq
MIRT1050127	hsa-miR-665	CLIP-seq
MIRT1050091	hsa-miR-23a	CLIP-seq
MIRT1050092	hsa-miR-23b	CLIP-seq
MIRT1050093	hsa-miR-23c	CLIP-seq
MIRT1050094	hsa-miR-3120-3p	CLIP-seq
MIRT2243700	hsa-miR-3162-5p	CLIP-seq
MIRT1050096	hsa-miR-34a	CLIP-seq
MIRT1050097	hsa-miR-34c-5p	CLIP-seq
MIRT1050100	hsa-miR-369-3p	CLIP-seq
MIRT1050101	hsa-miR-374a	CLIP-seq
MIRT1050102	hsa-miR-374b	CLIP-seq
MIRT1050105	hsa-miR-4326	CLIP-seq
MIRT1050107	hsa-miR-4477b	CLIP-seq
MIRT1050108	hsa-miR-449a	CLIP-seq
MIRT1050109	hsa-miR-449b	CLIP-seq
MIRT2243701	hsa-miR-4666-5p	CLIP-seq
MIRT1050089	hsa-miR-4792	CLIP-seq
MIRT1050090	hsa-miR-548m	CLIP-seq
MIRT1050091	hsa-miR-23a	CLIP-seq
MIRT1050092	hsa-miR-23b	CLIP-seq
MIRT1050093	hsa-miR-23c	CLIP-seq
MIRT1050096	hsa-miR-34a	CLIP-seq
MIRT1050097	hsa-miR-34c-5p	CLIP-seq
MIRT1050105	hsa-miR-4326	CLIP-seq
MIRT1050107	hsa-miR-4477b	CLIP-seq
MIRT1050108	hsa-miR-449a	CLIP-seq
MIRT1050109	hsa-miR-449b	CLIP-seq
MIRT2451278	hsa-miR-1273f	CLIP-seq
MIRT2451279	hsa-miR-143	CLIP-seq
MIRT2451280	hsa-miR-320e	CLIP-seq
MIRT2451281	hsa-miR-4263	CLIP-seq
MIRT2451282	hsa-miR-4708-5p	CLIP-seq
MIRT2451283	hsa-miR-4770	CLIP-seq
MIRT2451284	hsa-miR-586	CLIP-seq
MIRT2451285	hsa-miR-875-3p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
AR	Unknown	18174258

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22110403, 22666460, 25416956, 31515488
GO:0005540	Function	Hyaluronic acid binding	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS
GO:0009986	Component	Cell surface	IEA
GO:0010389	Process	Regulation of G2/M transition of mitotic cell cycle	TAS
GO:0015630	Component	Microtubule cytoskeleton	IDA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030214	Process	Hyaluronan catabolic process	TAS

Other IDs

• MIM: 600936
• HGNC: 5012
• e!Ensembl: ENSG00000072571

Protein

• UniProt ID: O75330
• Protein name: Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)
• Protein function: Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15905	HMMR_N	15 → 339	Hyaluronan mediated motility receptor N-terminal	Coiled-coil
  PF15908	HMMR_C	552 → 708	Hyaluronan mediated motility receptor C-terminal	Coiled-coil

• Tissue specificity: TISSUE SPECIFICITY: Expressed in testis (PubMed:22965910). Expressed in the breast (PubMed:8890751). {ECO:0000269|PubMed:22965910, ECO:0000269|PubMed:8890751}.
• Sequence:

  MSFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDT
  TLPASARKVKSSESKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLN
  AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK
  MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI
  SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK
  EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL
  CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL
  KGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSL
  QEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDL
  QNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAF
  EVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRC
  QLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPMECQ
  ESWK

• Sequence length: 724

Pathways

KEGG:

ECM-receptor interaction

Reactome:

Hyaluronan uptake and degradation
AURKA Activation by TPX2

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243	17922014
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	17922014
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465, rs137854466, rs137854467, rs387906547, rs387906548, rs137854469, rs137854473, rs1131692050, rs112989722, rs137854474, rs137854476, rs140593, rs1555395819, rs137854478, rs137854479, rs137854480, rs137854481, rs137854482, rs137854483, rs137854484, rs137854485, rs112289537, rs193922181, rs193922182, rs193922185, rs140603, rs193922187, rs193922188, rs193921256, rs112660651, rs193922193, rs193922194, rs193922197, rs193922198, rs193922199, rs193922203, rs193922204, rs193922205, rs193922206, rs111401431, rs193922207, rs113871094, rs111671429, rs193922216, rs193922219, rs193922220, rs193922223, rs193922224, rs193922225, rs193922226, rs193922227, rs193922228, rs193922230, rs193922235, rs147195031, rs193922236, rs193922239, rs193922240, rs193922241, rs193922246, rs397514558, rs398122934, rs397515753, rs397515754, rs397515755, rs397515756, rs397515757, rs113812345, rs397515758, rs397515759, rs397515762, rs25403, rs397515765, rs397515766, rs397515767, rs397515768, rs397515769, rs397515770, rs397515771, rs25404, rs397515773, rs397515774, rs397515775, rs397515776, rs397515778, rs397515779, rs397515781, rs112202622, rs397515782, rs397515784, rs397515785, rs397515786, rs397515788, rs397515789, rs397515790, rs397515791, rs397515792, rs397515793, rs397515794, rs397515797, rs397515798, rs397515799, rs397515801, rs397515802, rs397515803, rs397515804, rs397515805, rs397515808, rs397515810, rs397515811, rs397515812, rs111231312, rs267606798, rs397515814, rs113905529, rs397515816, rs397515817, rs397515818, rs397515819, rs397515820, rs363853, rs113249837, rs397515821, rs111929350, rs397515823, rs397515824, rs113086760, rs397515825, rs397515826, rs397515827, rs363807, rs397515828, rs397515829, rs397515830, rs397515831, rs397515833, rs111687884, rs113080385, rs397515834, rs397515836, rs113001196, rs397515840, rs397515845, rs397515846, rs397515847, rs397515848, rs397515851, rs397515852, rs397515853, rs397515854, rs111856492, rs397515859, rs397515861, rs397515863, rs397515864, rs397515865, rs397515866, rs397515867, rs137854855, rs199474693, rs587782944, rs587782947, rs587782948, rs672601352, rs876658120, rs727504651, rs727503054, rs727504315, rs727504411, rs727503057, rs727504454, rs200309328, rs363811, rs727504410, rs363821, rs727504347, rs727505006, rs727505110, rs730880356, rs727505269, rs727503058, rs727504421, rs730880107, rs730880104, rs730880103, rs730880102, rs730880101, rs730880106, rs730880100, rs730880105, rs730880099, rs112645512, rs730880108, rs730880098, rs730880097, rs794728321, rs794728283, rs794728280, rs794728336, rs794728272, rs794728160, rs794728271, rs794728270, rs794728319, rs794728262, rs794728251, rs76702162, rs794728335, rs794728334, rs794728246, rs763091520, rs794728333, rs794728237, rs761857514, rs794728234, rs140630, rs794728231, rs794728228, rs794728225, rs794728308, rs794728216, rs794728221, rs763449629, rs201058219, rs794728210, rs794728208, rs794728206, rs794728199, rs794728195, rs794728194, rs794728193, rs794728190, rs1555399381, rs794728176, rs1555399968, rs113422242, rs794728326, rs794728166, rs794728325, rs794728165, rs794728162, rs794728213, rs869025417, rs112642323, rs869025416, rs869025415, rs869025424, rs869025423, rs869025414, rs869025422, rs869025413, rs869025412, rs869025411, rs869025418, rs869025426, rs869025406, rs869025421, rs869025425, rs869025404, rs869025420, rs869025403, rs398122833, rs876657645, rs878853686, rs878853676, rs886038919, rs886038795, rs187553035, rs886038869, rs886038949, rs886038967, rs886038976, rs886038848, rs886038940, rs886038877, rs886039038, rs886038817, rs886038963, rs886039036, rs886038797, rs886039550, rs886041482, rs1057517855, rs1057518912, rs1057518973, rs1057519502, rs1057521100, rs1057521102, rs1057518881, rs1057520617, rs1057521101, rs1555394445, rs369058466, rs1060501069, rs1060501031, rs778966916, rs1060501043, rs1555397663, rs1060501017, rs1060501094, rs1060501065, rs1555393848, rs1555394151, rs1060501051, rs1060501013, rs1060501054, rs1060501048, rs1060501089, rs1060501039, rs1555398160, rs1060501022, rs1060501024, rs1060501086, rs1060501058, rs1060501036, rs1060501100, rs1060501042, rs1060501059, rs1555397743, rs1060501021, rs1060501027, rs1060501096, rs1060501038, rs1060501050, rs1064794130, rs112118237, rs1064793980, rs1064793118, rs1064793636, rs1064794282, rs1064793559, rs1085307921, rs1085308004, rs1085307468, rs112907302, rs1131691479, rs1131691373, rs1131691467, rs1131691938, rs1131691311, rs1131691806, rs1131691317, rs1555393827, rs363804, rs1555397738, rs1555399144, rs1555400274, rs1555394195, rs1555398836, rs113543334, rs1555399825, rs1555394626, rs1555395256, rs1555395257, rs1555396427, rs1555397548, rs1555398173, rs1555404803, rs1232880706, rs1555393825, rs1555394567, rs1555396998, rs1555394928, rs1555397203, rs112375043, rs1555397720, rs140599, rs1555399150, rs1555400373, rs1555405041, rs1555395229, rs1555397671, rs775417975, rs1555398774, rs1555399368, rs1555394904, rs1555395987, rs1555397424, rs1555398377, rs1555398835, rs1555401011, rs1555405043, rs1555394580, rs1555397404, rs1555398511, rs1555395826, rs1555399372, rs1555399821, rs1555399836, rs1555400063, rs363810, rs1555397655, rs1555395756, rs1555395742, rs1555393844, rs112550005, rs1555395002, rs1555395658, rs765387131, rs1555396429, rs1555396835, rs1555397014, rs1555397016, rs778710767, rs1555397557, rs1555397704, rs140648, rs1555398406, rs1555398681, rs1555399257, rs1555399361, rs1555399764, rs1555405056, rs1555393510, rs1555395980, rs1555396789, rs1555399094, rs1555399378, rs1555399816, rs1555395645, rs371097218, rs1555398278, rs1555394238, rs1555396418, rs1206813753, rs1555399271, rs1555405044, rs113544411, rs1555395663, rs1555397216, rs1555398989, rs1555399149, rs1555401670, rs1555395001, rs1445085747, rs1555393538, rs1555393565, rs1404133653, rs1555394450, rs1555394581, rs1555394633, rs1555394900, rs1555395189, rs1555395261, rs1052480459, rs1555395480, rs1555395670, rs363806, rs1555395820, rs1555396419, rs1555396765, rs1296209846, rs794728233, rs1555396853, rs1555396863, rs1555397197, rs1555397204, rs1555397212, rs1555397713, rs1555397736, rs1555398139, rs1555398144, rs1555398409, rs1555398510, rs1555398520, rs1555398524, rs1555398667, rs1555399089, rs1555399482, rs1555399763, rs1555401002, rs794728323, rs1555393508, rs1555393514, rs1555393525, rs1555393532, rs1555393653, rs1555393657, rs1555393824, rs1555393831, rs112196241, rs1555393847, rs1555393862, rs1555393863, rs1555393866, rs113935744, rs1555393882, rs1555393886, rs1555393889, rs1555394138, rs1555394144, rs1555394146, rs1555394148, rs1555394149, rs1555394152, rs1555394153, rs1555394189, rs1555394197, rs1555394206, rs1555394212, rs1555394218, rs1555394220, rs1555394235, rs1555394245, rs1555394246, rs1057520728, rs1555394390, rs1555394391, rs537570299, rs1555394397, rs1555394398, rs1555394399, rs1555394402, rs1555394407, rs1555394412, rs1555394435, rs1555394436, rs1555394441, rs1555394556, rs1555394557, rs1555394559, rs1555394561, rs1555394570, rs397515844, rs1555394571, rs1555394574, rs1555394579, rs1555394582, rs534811966, rs111588631, rs1555394628, rs1555394629, rs1555394630, rs1555394631, rs1555394641, rs1555394644, rs1555394647, rs1555394756, rs886051245, rs1555394775, rs1555394776, rs1555394777, rs1555394779, rs1555394780, rs1555394783, rs1555394901, rs1555394906, rs1555394925, rs794728253, rs886039158, rs1555395013, rs1555395187, rs1555395188, rs1555395203, rs1555395205, rs363815, rs1246984265, rs794728245, rs1555395263, rs1555395267, rs1555395456, rs1555395475, rs1555395482, rs1555395638, rs1555395641, rs1555395648, rs1555395653, rs1555395659, rs111239111, rs1555395745, rs1555395747, rs1555395753, rs1555395757, rs1555395766, rs1555395767, rs1555395843, rs1555395846, rs1555395849, rs1555395978, rs1555395981, rs1555395984, rs1555395989, rs1555395990, rs1260109901, rs1555396186, rs1555396188, rs1555396198, rs1555396199, rs1555396201, rs1555396202, rs1555396205, rs1555396213, rs1555396424, rs1555396426, rs1555396428, rs1555396435, rs1555396630, rs1555396635, rs1555396636, rs1555396639, rs1555396757, rs1555396769, rs1555396838, rs1555396844, rs140627, rs1555396858, rs1555396990, rs1555396991, rs1555396993, rs769588424, rs1555397022, rs1555397024, rs1555397160, rs1555397174, rs1555397176, rs1555397193, rs1555397209, rs1555397210, rs1555397214, rs1060501076, rs113082854, rs113693945, rs111978932, rs1555397403, rs1555397419, rs1555397420, rs1555397421, rs1555397536, rs1555397537, rs1555397540, rs1555397542, rs1555397543, rs1555397545, rs1555397546, rs1555397670, rs1555397692, rs1555397718, rs1555397723, rs1555397744, rs113393517, rs1555398148, rs1555398152, rs1555398174, rs1555398176, rs1555398179, rs1555398282, rs1555398287, rs1555398380, rs1555398394, rs1555398397, rs1555398401, rs1555398404, rs1555398407, rs1555398413, rs1555398501, rs1555398508, rs1555398512, rs1555398513, rs1555398515, rs1555398521, rs794728205, rs1555398527, rs1555398551, rs1060501075, rs1555398566, rs1555398572, rs1555398580, rs1555398582, rs140597, rs1555398622, rs1555398624, rs1555398625, rs112547596, rs1555398627, rs1555398633, rs1555398637, rs1555398642, rs778867355, rs1555398648, rs1555398659, rs1293095681, rs1060501040, rs987202268, rs1555398672, rs1555398673, rs1555398677, rs1555398793, rs1555398803, rs1555398811, rs1555398826, rs1555398833, rs1555398974, rs1555398981, rs778900586, rs1555398988, rs1555398994, rs1555398995, rs1555398996, rs1555399093, rs869025405, rs1555399101, rs1555399146, rs1555399160, rs1555399162, rs1555399164, rs1555399165, rs1555399193, rs1555399195, rs1555399202, rs1555399204, rs1555399206, rs201778577, rs1555399210, rs1555399214, rs1555399270, rs1555399273, rs1555399281, rs1555399371, rs1555399385, rs1555399477, rs1555399484, rs1555399761, rs1555399775, rs1555399802, rs1555399804, rs1555399837, rs1555399840, rs1555399940, rs1555399944, rs1555399949, rs1555399953, rs1555399954, rs1555399955, rs1555399959, rs1555399962, rs1555399963, rs1060501041, rs1555399974, rs1555399976, rs1555399977, rs1555400049, rs794728172, rs1555400062, rs1555400064, rs1555400066, rs1555400267, rs1555400268, rs1555400278, rs794728168, rs1555400279, rs1156747241, rs1555400288, rs1555400371, rs1555400372, rs1555400379, rs1555400385, rs587782943, rs1555400387, rs1555400406, rs1439533354, rs746201757, rs1555400595, rs1555400603, rs1555400604, rs1555400606, rs1555400609, rs752010116, rs1555400612, rs1555400616, rs1555401004, rs1555401005, rs146348130, rs1555401667, rs1555401671, rs1555401676, rs1555401679, rs1555401687, rs1555401689, rs1555401695, rs1555401697, rs1555401701, rs1555404799, rs1555404800, rs200295020, rs1555404810, rs1555404820, rs1555405031, rs1555405039, rs1555405045, rs1555405530, rs794728292, rs1555405533, rs1555405536, rs1555405537, rs111764111, rs1555405658, rs1555405664, rs774371494, rs1555405673, rs1555407399, rs1555407414, rs1555407423, rs1555407429, rs886041536, rs1555404806, rs1566911709, rs1566913974, rs1566894226, rs1566895223, rs1566897376, rs1566902526, rs1566915277, rs1566897374, rs1566897420, rs1566891655, rs1346043320, rs1566922396, rs1566891706, rs1566894783, rs1566913670, rs1555394196, rs1566891454, rs1566891406, rs1566891404, rs1566895262, rs1566891645, rs1566895225, rs1566896114, rs1566898399, rs1566904011, rs1566906537, rs1566908956, rs1566909766, rs1566919599, rs1566937712, rs1566915335, rs1566891675, rs1566904526, rs1566906506, rs1566900540, rs1566894230, rs1555395206, rs1566891797, rs1597512576, rs1597523873, rs1597581001, rs1597516325, rs1057524757, rs1597506641, rs1597520781, rs1597593695, rs1597529829, rs1597520625, rs1597579923, rs1597531796, rs1008275504, rs1597567249, rs1597569265, rs1597652471, rs1597516347, rs1597577114, rs1597633163, rs1597519658, rs1597593852, rs1597516501, rs1566913982, rs1555393859, rs1597513708, rs368978109, rs1480832655, rs1597520683, rs1597522390, rs1597522553, rs1597529748, rs1597533707, rs1597537815, rs1597545309, rs1597545836, rs1597563234, rs1597563280, rs1597564359, rs772108557, rs1597568968, rs1597574236, rs1597574308, rs1597577975, rs193922179, rs1597581005, rs1597593736, rs1597623670, rs1597625734, rs1597631662, rs113604459, rs1597633183, rs1597633219, rs1597518951, rs1555394781, rs1597525871, rs1597526073, rs1597569159, rs1597569536, rs1597563934, rs1597545199, rs1364210063, rs1597552583, rs1597520619, rs1597540854, rs1597591602, rs1597569551, rs1597548716, rs1597553721, rs112728248, rs1597537858, rs1597517935, rs1597540907, rs1597552388, rs1597591643, rs1597529841, rs1597506547, rs1597509836, rs1597529686, rs1566897404, rs1597533713, rs1597543486, rs1597545257, rs1597545345, rs1597548672, rs1597562812, rs1597563287, rs1597571391, rs1555400052, rs1597583989, rs363852, rs1597547226, rs363808, rs974604498, rs2043595650, rs2043526284, rs2042997306, rs1555397195, rs886039054, rs1555397213, rs2042873946	17922014

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma	Associate	33234735
Adenocarcinoma of Lung	Associate	30727821, 33187219, 34304612, 35810236, 36311801
Adenoma Oxyphilic	Associate	21887686
Bone Diseases	Stimulate	15105292
Breast Neoplasms	Associate	17392272, 22110403, 25830658, 28595038, 32705365, 33959662, 35577044, 36726984, 36930083, 37186300, 37713876
Calcinosis	Stimulate	34983451
Carcinogenesis	Associate	33849532, 35403252
Carcinoma Hepatocellular	Associate	31822116, 33540684, 33688500, 33784984, 34187556
Carcinoma Non Small Cell Lung	Associate	26439031, 29532892
Carcinoma Papillary	Stimulate	21887686
Carcinoma Papillary	Associate	31568988
Carcinoma Renal Cell	Stimulate	21887686
Carcinoma Squamous Cell	Associate	36938730
Carcinosarcoma	Stimulate	34111996
Colorectal Neoplasms	Associate	12384809, 16763611, 34051513
Colorectal Neoplasms Hereditary Nonpolyposis	Associate	16763611
Crohn Disease	Associate	10029598
Cysts	Associate	28954627
Disease	Stimulate	19724689
Endometrial Neoplasms	Associate	12712331
Fibrosarcoma	Associate	21914806
Glioblastoma	Associate	29574252, 30497369
Glioma	Associate	28161812, 36750807
Hearing Loss	Associate	36656851
Hereditary Breast and Ovarian Cancer Syndrome	Associate	25830658
Kidney Neoplasms	Associate	33287763
Leukemia	Associate	19724689, 22719778
Leukemia Hairy Cell	Associate	7678518
Leukemia Lymphocytic Chronic B Cell	Associate	19561536
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	17157168
Leukemia Myeloid Acute	Associate	15627212, 19724689, 22719778, 27659531
Leukocyte adhesion deficiency type 1	Associate	27659531
Lung Neoplasms	Associate	32831194, 37910672
Lupus Erythematosus Systemic	Associate	36726984
Lymphatic Metastasis	Associate	12712331
Mesothelioma Malignant	Associate	33849532
Mouth Neoplasms	Associate	36052378
Multiple Myeloma	Associate	10029598, 15105292, 17213289, 36737429
Multiple Myeloma	Stimulate	7678518
Myelodysplastic Syndromes	Associate	22719778
Neoplasm Metastasis	Associate	12712331, 18172264, 21435222, 24966934, 31847905, 33269813, 34051513
Neoplasm Metastasis	Stimulate	19724689
Neoplasms	Associate	12384809, 12712331, 16763611, 17392272, 20960509, 21435222, 21887686, 22970268, 24966934, 28161812, 28595038, 31568988, 34051513, 34187556, 34556750, 35577044, 37186300, 37713876
Neurofibrosarcoma	Associate	15255999
Non Muscle Invasive Bladder Neoplasms	Associate	31568988
Ovarian Neoplasms	Associate	23824740, 28591191, 28954627
Personality Disorders	Associate	15105292
Primary Ovarian Insufficiency	Associate	36732629
Prostate Cancer Hereditary 7	Associate	24708576
Prostatic Neoplasms	Associate	19724689, 26456171
Squamous Cell Carcinoma of Head and Neck	Associate	35232899, 39323031
Stomach Neoplasms	Associate	21435222
Tachycardia Atrioventricular Nodal Reentry	Stimulate	21435222
Urinary Bladder Neoplasms	Associate	20960509, 27595989
Uterine Cervical Neoplasms	Associate	24966934