HMGB3 (high mobility group box 3)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3149 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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High mobility group box 3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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HMGB3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HMG-2a, HMG-4, HMG2A, HMG4 |
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Chromosome
Chromosome number
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X |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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Xq28 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | O15347 | |||||||||||||||
| Protein name | High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4) | |||||||||||||||
| Protein function | Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference for non-canonical DNA structures such as single-stranded DNA. Can bend | |||||||||||||||
| PDB | 2EQZ , 2YQI | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed predominantly in placenta. | |||||||||||||||
| Sequence |
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| Sequence length | 200 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||