Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3133
Gene name Gene Name - the full gene name approved by the HGNC.	Major histocompatibility complex, class I, E
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HLA-E
Synonyms (NCBI Gene) Gene synonyms aliases	HLA-6.2, QA1
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p22.1
Summary Summary of gene provided in NCBI Entrez Gene.	HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides

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miRTarBase ID	miRNA	Experiments	Reference
MIRT049514	hsa-miR-92a-3p	CLASH	23622248
MIRT038407	hsa-miR-296-3p	CLASH	23622248
MIRT722051	hsa-miR-124-3p	HITS-CLIP	19536157
MIRT722049	hsa-miR-5582-5p	HITS-CLIP	19536157
MIRT722048	hsa-miR-605-3p	HITS-CLIP	19536157
MIRT722047	hsa-miR-4493	HITS-CLIP	19536157
MIRT722046	hsa-miR-6126	HITS-CLIP	19536157
MIRT722045	hsa-miR-6770-5p	HITS-CLIP	19536157
MIRT618780	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT618779	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT618778	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT618777	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT618776	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT618775	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT618774	hsa-miR-3135b	HITS-CLIP	23824327
MIRT618773	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT618772	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT618771	hsa-miR-3652	HITS-CLIP	23824327
MIRT618770	hsa-miR-4430	HITS-CLIP	23824327
MIRT618769	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT618768	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT618767	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT618780	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT618779	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT618778	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT618777	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT618776	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT618775	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT618774	hsa-miR-3135b	HITS-CLIP	23824327
MIRT618773	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT618772	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT618771	hsa-miR-3652	HITS-CLIP	23824327
MIRT618770	hsa-miR-4430	HITS-CLIP	23824327
MIRT618769	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT618768	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT618767	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT618780	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT618779	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT618778	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT618777	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT618776	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT618775	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT618774	hsa-miR-3135b	HITS-CLIP	23824327
MIRT618773	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT618772	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT618771	hsa-miR-3652	HITS-CLIP	23824327
MIRT618770	hsa-miR-4430	HITS-CLIP	23824327
MIRT618769	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT618768	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT618767	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT440496	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440496	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT722051	hsa-miR-124-3p	HITS-CLIP	19536157
MIRT722049	hsa-miR-5582-5p	HITS-CLIP	19536157
MIRT722048	hsa-miR-605-3p	HITS-CLIP	19536157
MIRT722047	hsa-miR-4493	HITS-CLIP	19536157
MIRT722046	hsa-miR-6126	HITS-CLIP	19536157
MIRT722045	hsa-miR-6770-5p	HITS-CLIP	19536157
MIRT618780	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT618779	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT618778	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT618777	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT618776	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT618775	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT618774	hsa-miR-3135b	HITS-CLIP	23824327
MIRT618773	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT618772	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT618771	hsa-miR-3652	HITS-CLIP	23824327
MIRT618770	hsa-miR-4430	HITS-CLIP	23824327
MIRT618769	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT618768	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT618767	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT618780	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT618779	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT618778	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT618777	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT618776	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT618775	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT618774	hsa-miR-3135b	HITS-CLIP	23824327
MIRT618773	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT618772	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT618771	hsa-miR-3652	HITS-CLIP	23824327
MIRT618770	hsa-miR-4430	HITS-CLIP	23824327
MIRT618769	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT618768	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT618767	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT618780	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT618779	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT618778	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT618777	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT618776	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT618775	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT618774	hsa-miR-3135b	HITS-CLIP	23824327
MIRT618773	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT618772	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT618771	hsa-miR-3652	HITS-CLIP	23824327
MIRT618770	hsa-miR-4430	HITS-CLIP	23824327
MIRT618769	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT618768	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT618767	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT1048484	hsa-miR-1193	CLIP-seq
MIRT1048485	hsa-miR-1200	CLIP-seq
MIRT1048486	hsa-miR-1252	CLIP-seq
MIRT1048487	hsa-miR-1269	CLIP-seq
MIRT1048488	hsa-miR-1269b	CLIP-seq
MIRT1048489	hsa-miR-1281	CLIP-seq
MIRT1048490	hsa-miR-1288	CLIP-seq
MIRT1048491	hsa-miR-1294	CLIP-seq
MIRT1048492	hsa-miR-129-5p	CLIP-seq
MIRT1048493	hsa-miR-1324	CLIP-seq
MIRT1048494	hsa-miR-1913	CLIP-seq
MIRT1048495	hsa-miR-1976	CLIP-seq
MIRT1048496	hsa-miR-2116	CLIP-seq
MIRT1048497	hsa-miR-22	CLIP-seq
MIRT1048498	hsa-miR-2392	CLIP-seq
MIRT1048499	hsa-miR-3123	CLIP-seq
MIRT1048500	hsa-miR-3149	CLIP-seq
MIRT1048501	hsa-miR-3152-3p	CLIP-seq
MIRT1048502	hsa-miR-3160-3p	CLIP-seq
MIRT1048503	hsa-miR-3179	CLIP-seq
MIRT1048504	hsa-miR-3190	CLIP-seq
MIRT1048505	hsa-miR-3199	CLIP-seq
MIRT1048506	hsa-miR-3202	CLIP-seq
MIRT1048507	hsa-miR-324-3p	CLIP-seq
MIRT1048508	hsa-miR-3529	CLIP-seq
MIRT1048509	hsa-miR-3617	CLIP-seq
MIRT1048510	hsa-miR-379	CLIP-seq
MIRT1048511	hsa-miR-3915	CLIP-seq
MIRT1048512	hsa-miR-3925-5p	CLIP-seq
MIRT1048513	hsa-miR-3928	CLIP-seq
MIRT1048514	hsa-miR-411	CLIP-seq
MIRT1048515	hsa-miR-4257	CLIP-seq
MIRT1048516	hsa-miR-4279	CLIP-seq
MIRT1048517	hsa-miR-4290	CLIP-seq
MIRT1048518	hsa-miR-4302	CLIP-seq
MIRT1048519	hsa-miR-4311	CLIP-seq
MIRT1048520	hsa-miR-4316	CLIP-seq
MIRT1048521	hsa-miR-4324	CLIP-seq
MIRT1048522	hsa-miR-4438	CLIP-seq
MIRT1048523	hsa-miR-4451	CLIP-seq
MIRT1048524	hsa-miR-4476	CLIP-seq
MIRT1048525	hsa-miR-4487	CLIP-seq
MIRT1048526	hsa-miR-4515	CLIP-seq
MIRT1048527	hsa-miR-4532	CLIP-seq
MIRT1048528	hsa-miR-4533	CLIP-seq
MIRT1048529	hsa-miR-4650-3p	CLIP-seq
MIRT1048530	hsa-miR-4662a-5p	CLIP-seq
MIRT1048531	hsa-miR-4667-3p	CLIP-seq
MIRT1048532	hsa-miR-4676-5p	CLIP-seq
MIRT1048533	hsa-miR-4697-3p	CLIP-seq
MIRT1048534	hsa-miR-4722-3p	CLIP-seq
MIRT1048535	hsa-miR-4726-3p	CLIP-seq
MIRT1048536	hsa-miR-4735-5p	CLIP-seq
MIRT1048537	hsa-miR-4740-5p	CLIP-seq
MIRT1048538	hsa-miR-4747-3p	CLIP-seq
MIRT1048539	hsa-miR-4747-5p	CLIP-seq
MIRT1048540	hsa-miR-4773	CLIP-seq
MIRT1048541	hsa-miR-4775	CLIP-seq
MIRT1048542	hsa-miR-4786-3p	CLIP-seq
MIRT1048543	hsa-miR-4789-3p	CLIP-seq
MIRT1048544	hsa-miR-483-5p	CLIP-seq
MIRT1048545	hsa-miR-5095	CLIP-seq
MIRT1048546	hsa-miR-513a-3p	CLIP-seq
MIRT1048547	hsa-miR-544b	CLIP-seq
MIRT1048548	hsa-miR-558	CLIP-seq
MIRT1048549	hsa-miR-563	CLIP-seq
MIRT1048550	hsa-miR-575	CLIP-seq
MIRT1048551	hsa-miR-576-3p	CLIP-seq
MIRT1048552	hsa-miR-590-3p	CLIP-seq
MIRT1048553	hsa-miR-633	CLIP-seq
MIRT1048554	hsa-miR-641	CLIP-seq
MIRT1048555	hsa-miR-642b	CLIP-seq
MIRT1549535	hsa-miR-4457	CLIP-seq
MIRT1556537	hsa-miR-3682-5p	CLIP-seq
MIRT1556538	hsa-miR-3973	CLIP-seq
MIRT1556539	hsa-miR-4330	CLIP-seq
MIRT1556540	hsa-miR-4777-3p	CLIP-seq
MIRT1556541	hsa-miR-520g	CLIP-seq
MIRT1556542	hsa-miR-520h	CLIP-seq
MIRT1556543	hsa-miR-561	CLIP-seq
MIRT2011029	hsa-miR-10a	CLIP-seq
MIRT2011030	hsa-miR-10b	CLIP-seq
MIRT1048485	hsa-miR-1200	CLIP-seq
MIRT2011031	hsa-miR-122	CLIP-seq
MIRT1048489	hsa-miR-1281	CLIP-seq
MIRT2011032	hsa-miR-142-5p	CLIP-seq
MIRT1048494	hsa-miR-1913	CLIP-seq
MIRT1048495	hsa-miR-1976	CLIP-seq
MIRT1048499	hsa-miR-3123	CLIP-seq
MIRT2011033	hsa-miR-3145-5p	CLIP-seq
MIRT1048507	hsa-miR-324-3p	CLIP-seq
MIRT2011034	hsa-miR-340	CLIP-seq
MIRT2011035	hsa-miR-3620	CLIP-seq
MIRT1048512	hsa-miR-3925-5p	CLIP-seq
MIRT1048516	hsa-miR-4279	CLIP-seq
MIRT1048517	hsa-miR-4290	CLIP-seq
MIRT1048518	hsa-miR-4302	CLIP-seq
MIRT1048521	hsa-miR-4324	CLIP-seq
MIRT1048522	hsa-miR-4438	CLIP-seq
MIRT1048531	hsa-miR-4667-3p	CLIP-seq
MIRT1048533	hsa-miR-4697-3p	CLIP-seq
MIRT1048534	hsa-miR-4722-3p	CLIP-seq
MIRT1048545	hsa-miR-5095	CLIP-seq
MIRT1048547	hsa-miR-544b	CLIP-seq
MIRT2011036	hsa-miR-552	CLIP-seq
MIRT2243314	hsa-miR-1238	CLIP-seq
MIRT1048489	hsa-miR-1281	CLIP-seq
MIRT2011032	hsa-miR-142-5p	CLIP-seq
MIRT2243315	hsa-miR-2117	CLIP-seq
MIRT2243316	hsa-miR-3130-3p	CLIP-seq
MIRT1048501	hsa-miR-3152-3p	CLIP-seq
MIRT2011034	hsa-miR-340	CLIP-seq
MIRT2243317	hsa-miR-3688-5p	CLIP-seq
MIRT1048514	hsa-miR-411	CLIP-seq
MIRT2243318	hsa-miR-4446-5p	CLIP-seq
MIRT2243319	hsa-miR-4456	CLIP-seq
MIRT1048527	hsa-miR-4532	CLIP-seq
MIRT1048530	hsa-miR-4662a-5p	CLIP-seq
MIRT1048532	hsa-miR-4676-5p	CLIP-seq
MIRT2243320	hsa-miR-4753-3p	CLIP-seq
MIRT2243321	hsa-miR-4755-5p	CLIP-seq
MIRT2243322	hsa-miR-4778-3p	CLIP-seq
MIRT1048544	hsa-miR-483-5p	CLIP-seq
MIRT2243323	hsa-miR-5096	CLIP-seq
MIRT1048549	hsa-miR-563	CLIP-seq
MIRT1048550	hsa-miR-575	CLIP-seq
MIRT2243324	hsa-miR-670	CLIP-seq
MIRT2243325	hsa-miR-885-3p	CLIP-seq
MIRT1556537	hsa-miR-3682-5p	CLIP-seq
MIRT1048511	hsa-miR-3915	CLIP-seq
MIRT1048513	hsa-miR-3928	CLIP-seq
MIRT2389017	hsa-miR-4264	CLIP-seq
MIRT2389018	hsa-miR-4797-3p	CLIP-seq
MIRT2437619	hsa-miR-3117-5p	CLIP-seq
MIRT2437620	hsa-miR-4292	CLIP-seq
MIRT2437621	hsa-miR-4305	CLIP-seq
MIRT2437622	hsa-miR-4308	CLIP-seq
MIRT2243318	hsa-miR-4446-5p	CLIP-seq
MIRT2437623	hsa-miR-4704-5p	CLIP-seq
MIRT2243321	hsa-miR-4755-5p	CLIP-seq
MIRT2243324	hsa-miR-670	CLIP-seq
MIRT1048485	hsa-miR-1200	CLIP-seq
MIRT2011031	hsa-miR-122	CLIP-seq
MIRT2546440	hsa-miR-124	CLIP-seq
MIRT2546441	hsa-miR-1254	CLIP-seq
MIRT2546442	hsa-miR-1264	CLIP-seq
MIRT2546443	hsa-miR-1273d	CLIP-seq
MIRT1048489	hsa-miR-1281	CLIP-seq
MIRT1048492	hsa-miR-129-5p	CLIP-seq
MIRT2546444	hsa-miR-138	CLIP-seq
MIRT2546445	hsa-miR-140-3p	CLIP-seq
MIRT2011032	hsa-miR-142-5p	CLIP-seq
MIRT2546446	hsa-miR-149	CLIP-seq
MIRT2546447	hsa-miR-181a	CLIP-seq
MIRT2546448	hsa-miR-181b	CLIP-seq
MIRT2546449	hsa-miR-181c	CLIP-seq
MIRT2546450	hsa-miR-181d	CLIP-seq
MIRT2546451	hsa-miR-1914	CLIP-seq
MIRT1048495	hsa-miR-1976	CLIP-seq
MIRT2546452	hsa-miR-23a	CLIP-seq
MIRT2546453	hsa-miR-23b	CLIP-seq
MIRT2546454	hsa-miR-23c	CLIP-seq
MIRT2546455	hsa-miR-24	CLIP-seq
MIRT2546456	hsa-miR-296-5p	CLIP-seq
MIRT2546457	hsa-miR-3064-3p	CLIP-seq
MIRT2546458	hsa-miR-3116	CLIP-seq
MIRT2437619	hsa-miR-3117-5p	CLIP-seq
MIRT2546459	hsa-miR-3119	CLIP-seq
MIRT1048499	hsa-miR-3123	CLIP-seq
MIRT2243316	hsa-miR-3130-3p	CLIP-seq
MIRT2011033	hsa-miR-3145-5p	CLIP-seq
MIRT1048500	hsa-miR-3149	CLIP-seq
MIRT2546460	hsa-miR-3162-5p	CLIP-seq
MIRT1048505	hsa-miR-3199	CLIP-seq
MIRT2546461	hsa-miR-320a	CLIP-seq
MIRT2546462	hsa-miR-320b	CLIP-seq
MIRT2546463	hsa-miR-320c	CLIP-seq
MIRT2546464	hsa-miR-320d	CLIP-seq
MIRT2546465	hsa-miR-323-5p	CLIP-seq
MIRT2546466	hsa-miR-338-5p	CLIP-seq
MIRT2011034	hsa-miR-340	CLIP-seq
MIRT2546467	hsa-miR-3659	CLIP-seq
MIRT2243317	hsa-miR-3688-5p	CLIP-seq
MIRT2546468	hsa-miR-3689a-5p	CLIP-seq
MIRT2546469	hsa-miR-3689b	CLIP-seq
MIRT2546470	hsa-miR-3689e	CLIP-seq
MIRT2546471	hsa-miR-3689f	CLIP-seq
MIRT2546472	hsa-miR-3692	CLIP-seq
MIRT2546473	hsa-miR-370	CLIP-seq
MIRT2546474	hsa-miR-371-5p	CLIP-seq
MIRT2546475	hsa-miR-371b-5p	CLIP-seq
MIRT2546476	hsa-miR-3922-5p	CLIP-seq
MIRT1048512	hsa-miR-3925-5p	CLIP-seq
MIRT2546477	hsa-miR-3940-5p	CLIP-seq
MIRT2546478	hsa-miR-3943	CLIP-seq
MIRT2546479	hsa-miR-3944-5p	CLIP-seq
MIRT1048514	hsa-miR-411	CLIP-seq
MIRT2546480	hsa-miR-4252	CLIP-seq
MIRT2546481	hsa-miR-4262	CLIP-seq
MIRT2546482	hsa-miR-4272	CLIP-seq
MIRT2546483	hsa-miR-4277	CLIP-seq
MIRT1048516	hsa-miR-4279	CLIP-seq
MIRT2546484	hsa-miR-4284	CLIP-seq
MIRT2437620	hsa-miR-4292	CLIP-seq
MIRT2437621	hsa-miR-4305	CLIP-seq
MIRT2437622	hsa-miR-4308	CLIP-seq
MIRT2546485	hsa-miR-4314	CLIP-seq
MIRT2546486	hsa-miR-4323	CLIP-seq
MIRT1048521	hsa-miR-4324	CLIP-seq
MIRT2546487	hsa-miR-4429	CLIP-seq
MIRT2546488	hsa-miR-4436b-5p	CLIP-seq
MIRT1048522	hsa-miR-4438	CLIP-seq
MIRT2546489	hsa-miR-4443	CLIP-seq
MIRT2243318	hsa-miR-4446-5p	CLIP-seq
MIRT2546490	hsa-miR-4447	CLIP-seq
MIRT2243319	hsa-miR-4456	CLIP-seq
MIRT1549535	hsa-miR-4457	CLIP-seq
MIRT2546491	hsa-miR-4472	CLIP-seq
MIRT2546492	hsa-miR-4474-3p	CLIP-seq
MIRT2546493	hsa-miR-4488	CLIP-seq
MIRT2546494	hsa-miR-4506	CLIP-seq
MIRT2546495	hsa-miR-4507	CLIP-seq
MIRT1048527	hsa-miR-4532	CLIP-seq
MIRT2546496	hsa-miR-4639-3p	CLIP-seq
MIRT2546497	hsa-miR-4658	CLIP-seq
MIRT2546498	hsa-miR-4667-5p	CLIP-seq
MIRT2546499	hsa-miR-4679	CLIP-seq
MIRT2546500	hsa-miR-4697-5p	CLIP-seq
MIRT2546501	hsa-miR-4700-5p	CLIP-seq
MIRT2437623	hsa-miR-4704-5p	CLIP-seq
MIRT1048534	hsa-miR-4722-3p	CLIP-seq
MIRT2546502	hsa-miR-4731-5p	CLIP-seq
MIRT1048536	hsa-miR-4735-5p	CLIP-seq
MIRT2546503	hsa-miR-4738-5p	CLIP-seq
MIRT1048538	hsa-miR-4747-3p	CLIP-seq
MIRT2243321	hsa-miR-4755-5p	CLIP-seq
MIRT2546504	hsa-miR-4758-3p	CLIP-seq
MIRT2546505	hsa-miR-4772-3p	CLIP-seq
MIRT1048541	hsa-miR-4775	CLIP-seq
MIRT2243322	hsa-miR-4778-3p	CLIP-seq
MIRT2546506	hsa-miR-506	CLIP-seq
MIRT1048545	hsa-miR-5095	CLIP-seq
MIRT1048546	hsa-miR-513a-3p	CLIP-seq
MIRT2546507	hsa-miR-541	CLIP-seq
MIRT2546508	hsa-miR-543	CLIP-seq
MIRT1048547	hsa-miR-544b	CLIP-seq
MIRT2546509	hsa-miR-548q	CLIP-seq
MIRT2546510	hsa-miR-550a	CLIP-seq
MIRT2011036	hsa-miR-552	CLIP-seq
MIRT1048549	hsa-miR-563	CLIP-seq
MIRT2546511	hsa-miR-570	CLIP-seq
MIRT2546512	hsa-miR-574-5p	CLIP-seq
MIRT1048552	hsa-miR-590-3p	CLIP-seq
MIRT2546513	hsa-miR-603	CLIP-seq
MIRT2546514	hsa-miR-604	CLIP-seq
MIRT2546515	hsa-miR-615-5p	CLIP-seq
MIRT2546516	hsa-miR-637	CLIP-seq
MIRT2546517	hsa-miR-647	CLIP-seq
MIRT2546518	hsa-miR-654-5p	CLIP-seq
MIRT2546519	hsa-miR-660	CLIP-seq
MIRT2546520	hsa-miR-663b	CLIP-seq
MIRT2243324	hsa-miR-670	CLIP-seq
MIRT2546521	hsa-miR-876-3p	CLIP-seq
MIRT2243325	hsa-miR-885-3p	CLIP-seq
MIRT2546522	hsa-miR-885-5p	CLIP-seq
MIRT1048485	hsa-miR-1200	CLIP-seq
MIRT2011031	hsa-miR-122	CLIP-seq
MIRT2546440	hsa-miR-124	CLIP-seq
MIRT2546441	hsa-miR-1254	CLIP-seq
MIRT2546442	hsa-miR-1264	CLIP-seq
MIRT2546443	hsa-miR-1273d	CLIP-seq
MIRT1048489	hsa-miR-1281	CLIP-seq
MIRT1048492	hsa-miR-129-5p	CLIP-seq
MIRT2546444	hsa-miR-138	CLIP-seq
MIRT2546445	hsa-miR-140-3p	CLIP-seq
MIRT2546446	hsa-miR-149	CLIP-seq
MIRT2546447	hsa-miR-181a	CLIP-seq
MIRT2546448	hsa-miR-181b	CLIP-seq
MIRT2546449	hsa-miR-181c	CLIP-seq
MIRT2546450	hsa-miR-181d	CLIP-seq
MIRT2546451	hsa-miR-1914	CLIP-seq
MIRT1048495	hsa-miR-1976	CLIP-seq
MIRT2546452	hsa-miR-23a	CLIP-seq
MIRT2546453	hsa-miR-23b	CLIP-seq
MIRT2546454	hsa-miR-23c	CLIP-seq
MIRT2546455	hsa-miR-24	CLIP-seq
MIRT2546456	hsa-miR-296-5p	CLIP-seq
MIRT2546457	hsa-miR-3064-3p	CLIP-seq
MIRT2546458	hsa-miR-3116	CLIP-seq
MIRT2437619	hsa-miR-3117-5p	CLIP-seq
MIRT2546459	hsa-miR-3119	CLIP-seq
MIRT1048499	hsa-miR-3123	CLIP-seq
MIRT2243316	hsa-miR-3130-3p	CLIP-seq
MIRT2011033	hsa-miR-3145-5p	CLIP-seq
MIRT1048500	hsa-miR-3149	CLIP-seq
MIRT2546460	hsa-miR-3162-5p	CLIP-seq
MIRT1048505	hsa-miR-3199	CLIP-seq
MIRT2546461	hsa-miR-320a	CLIP-seq
MIRT2546462	hsa-miR-320b	CLIP-seq
MIRT2546463	hsa-miR-320c	CLIP-seq
MIRT2546464	hsa-miR-320d	CLIP-seq
MIRT2546465	hsa-miR-323-5p	CLIP-seq
MIRT2546466	hsa-miR-338-5p	CLIP-seq
MIRT2546467	hsa-miR-3659	CLIP-seq
MIRT2243317	hsa-miR-3688-5p	CLIP-seq
MIRT2546473	hsa-miR-370	CLIP-seq
MIRT2546476	hsa-miR-3922-5p	CLIP-seq
MIRT1048512	hsa-miR-3925-5p	CLIP-seq
MIRT2546477	hsa-miR-3940-5p	CLIP-seq
MIRT2546478	hsa-miR-3943	CLIP-seq
MIRT2546479	hsa-miR-3944-5p	CLIP-seq
MIRT1048514	hsa-miR-411	CLIP-seq
MIRT2546481	hsa-miR-4262	CLIP-seq
MIRT2546482	hsa-miR-4272	CLIP-seq
MIRT2546483	hsa-miR-4277	CLIP-seq
MIRT1048516	hsa-miR-4279	CLIP-seq
MIRT2546484	hsa-miR-4284	CLIP-seq
MIRT2437620	hsa-miR-4292	CLIP-seq
MIRT2437621	hsa-miR-4305	CLIP-seq
MIRT2437622	hsa-miR-4308	CLIP-seq
MIRT2546485	hsa-miR-4314	CLIP-seq
MIRT2546486	hsa-miR-4323	CLIP-seq
MIRT1048521	hsa-miR-4324	CLIP-seq
MIRT2546487	hsa-miR-4429	CLIP-seq
MIRT1048522	hsa-miR-4438	CLIP-seq
MIRT2546489	hsa-miR-4443	CLIP-seq
MIRT2243318	hsa-miR-4446-5p	CLIP-seq
MIRT2546490	hsa-miR-4447	CLIP-seq
MIRT2243319	hsa-miR-4456	CLIP-seq
MIRT1549535	hsa-miR-4457	CLIP-seq
MIRT2546491	hsa-miR-4472	CLIP-seq
MIRT2546492	hsa-miR-4474-3p	CLIP-seq
MIRT2546493	hsa-miR-4488	CLIP-seq
MIRT2546494	hsa-miR-4506	CLIP-seq
MIRT2546495	hsa-miR-4507	CLIP-seq
MIRT1048527	hsa-miR-4532	CLIP-seq
MIRT2546496	hsa-miR-4639-3p	CLIP-seq
MIRT2546497	hsa-miR-4658	CLIP-seq
MIRT2546498	hsa-miR-4667-5p	CLIP-seq
MIRT2546500	hsa-miR-4697-5p	CLIP-seq
MIRT2546501	hsa-miR-4700-5p	CLIP-seq
MIRT2437623	hsa-miR-4704-5p	CLIP-seq
MIRT1048534	hsa-miR-4722-3p	CLIP-seq
MIRT2546502	hsa-miR-4731-5p	CLIP-seq
MIRT1048536	hsa-miR-4735-5p	CLIP-seq
MIRT2546503	hsa-miR-4738-5p	CLIP-seq
MIRT1048538	hsa-miR-4747-3p	CLIP-seq
MIRT2243321	hsa-miR-4755-5p	CLIP-seq
MIRT2546505	hsa-miR-4772-3p	CLIP-seq
MIRT1048541	hsa-miR-4775	CLIP-seq
MIRT2546506	hsa-miR-506	CLIP-seq
MIRT1048545	hsa-miR-5095	CLIP-seq
MIRT2546507	hsa-miR-541	CLIP-seq
MIRT2546508	hsa-miR-543	CLIP-seq
MIRT1048547	hsa-miR-544b	CLIP-seq
MIRT2546509	hsa-miR-548q	CLIP-seq
MIRT2546510	hsa-miR-550a	CLIP-seq
MIRT2011036	hsa-miR-552	CLIP-seq
MIRT1048549	hsa-miR-563	CLIP-seq
MIRT2546511	hsa-miR-570	CLIP-seq
MIRT2546512	hsa-miR-574-5p	CLIP-seq
MIRT1048552	hsa-miR-590-3p	CLIP-seq
MIRT2546513	hsa-miR-603	CLIP-seq
MIRT2546514	hsa-miR-604	CLIP-seq
MIRT2546515	hsa-miR-615-5p	CLIP-seq
MIRT2546516	hsa-miR-637	CLIP-seq
MIRT2546517	hsa-miR-647	CLIP-seq
MIRT2546518	hsa-miR-654-5p	CLIP-seq
MIRT2546519	hsa-miR-660	CLIP-seq
MIRT2546520	hsa-miR-663b	CLIP-seq
MIRT2243324	hsa-miR-670	CLIP-seq
MIRT2546521	hsa-miR-876-3p	CLIP-seq
MIRT2243325	hsa-miR-885-3p	CLIP-seq
MIRT2546522	hsa-miR-885-5p	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
HIVEP2	Unknown	1409593
MYC	Activation	8206526
MYCN	Unknown	8895520
STAT1	Unknown	11137213

Show/Hide all(77)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0001815	Process	Positive regulation of antibody-dependent cellular cytotoxicity	IDA	30134159
GO:0001916	Process	Positive regulation of T cell mediated cytotoxicity	IBA
GO:0001916	Process	Positive regulation of T cell mediated cytotoxicity	IDA	20195504, 25631937
GO:0002228	Process	Natural killer cell mediated immunity	IDA	9655483, 18448674
GO:0002250	Process	Adaptive immune response	IDA	25631937
GO:0002250	Process	Adaptive immune response	IEA
GO:0002376	Process	Immune system process	IEA
GO:0002474	Process	Antigen processing and presentation of peptide antigen via MHC class I	IEA
GO:0002476	Process	Antigen processing and presentation of endogenous peptide antigen via MHC class Ib	IBA
GO:0002476	Process	Antigen processing and presentation of endogenous peptide antigen via MHC class Ib	IDA	9754572
GO:0002477	Process	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib	IDA	20195504, 30087334
GO:0002486	Process	Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	IBA
GO:0002519	Process	Natural killer cell tolerance induction	IDA	9486650
GO:0002639	Process	Positive regulation of immunoglobulin production	IDA	25631937
GO:0002715	Process	Regulation of natural killer cell mediated immunity	IDA	18448674
GO:0002717	Process	Positive regulation of natural killer cell mediated immunity	IDA	9754572
GO:0002729	Process	Positive regulation of natural killer cell cytokine production	IDA	30134159
GO:0005102	Function	Signaling receptor binding	IBA
GO:0005102	Function	Signaling receptor binding	IPI	18448674
GO:0005515	Function	Protein binding	IPI	9427624, 18083576, 20483783, 33961781
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IDA	17179229
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IDA	9427624, 17179229
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006955	Process	Immune response	IBA
GO:0006955	Process	Immune response	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0009897	Component	External side of plasma membrane	IBA
GO:0009986	Component	Cell surface	IDA	9754572, 12411439, 25631937
GO:0009986	Component	Cell surface	IEA
GO:0012507	Component	ER to Golgi transport vesicle membrane	IEA
GO:0012507	Component	ER to Golgi transport vesicle membrane	TAS
GO:0016020	Component	Membrane	IEA
GO:0019731	Process	Antibacterial humoral response	IDA	25631937
GO:0019882	Process	Antigen processing and presentation	IEA
GO:0030670	Component	Phagocytic vesicle membrane	IEA
GO:0030670	Component	Phagocytic vesicle membrane	TAS
GO:0030881	Function	Beta-2-microglobulin binding	IDA	16474394, 18339401, 18448674, 25631937, 30087334
GO:0030881	Function	Beta-2-microglobulin binding	IMP	12411439
GO:0031901	Component	Early endosome membrane	IEA
GO:0031901	Component	Early endosome membrane	TAS
GO:0032398	Component	MHC class Ib protein complex	IDA	9427624, 20195504, 23335510, 25631937, 30087334, 37264229
GO:0032736	Process	Positive regulation of interleukin-13 production	IDA	25631937
GO:0032753	Process	Positive regulation of interleukin-4 production	IDA	25631937
GO:0032759	Process	Positive regulation of TRAIL production	IDA	25631937
GO:0032760	Process	Positive regulation of tumor necrosis factor production	IDA	25631937
GO:0032815	Process	Negative regulation of natural killer cell activation	IDA	37264229
GO:0032816	Process	Positive regulation of natural killer cell activation	IDA	37264229
GO:0032819	Process	Positive regulation of natural killer cell proliferation	IDA	30134159
GO:0036037	Process	CD8-positive, alpha-beta T cell activation	IDA	25631937
GO:0042130	Process	Negative regulation of T cell proliferation	IDA	20195504
GO:0042270	Process	Protection from natural killer cell mediated cytotoxicity	IDA	9754572, 25631937
GO:0042288	Function	MHC class I protein binding	IDA	9754572
GO:0042605	Function	Peptide antigen binding	IBA
GO:0042605	Function	Peptide antigen binding	IDA	9427624, 9486650, 9754572, 10799855, 16474394, 18083576, 18339401, 18448674, 23335510, 25631937, 30087334
GO:0042605	Function	Peptide antigen binding	IMP	12411439
GO:0042608	Function	T cell receptor binding	IDA	16474394
GO:0042612	Component	MHC class I protein complex	IDA	12411439, 16474394, 18448674
GO:0042612	Component	MHC class I protein complex	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0045953	Process	Negative regulation of natural killer cell mediated cytotoxicity	IDA	9486650, 10799855, 17179229, 23335510
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	IDA	23335510
GO:0046703	Function	Natural killer cell lectin-like receptor binding	IPI	25631937
GO:0048018	Function	Receptor ligand activity	IDA	25631937
GO:0050830	Process	Defense response to Gram-positive bacterium	IDA	25631937
GO:0055038	Component	Recycling endosome membrane	IEA
GO:0055038	Component	Recycling endosome membrane	TAS
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0098553	Component	Lumenal side of endoplasmic reticulum membrane	IEA
GO:0098553	Component	Lumenal side of endoplasmic reticulum membrane	TAS
GO:2000566	Process	Positive regulation of CD8-positive, alpha-beta T cell proliferation	IDA	25631937
GO:2001187	Process	Positive regulation of CD8-positive, alpha-beta T cell activation	IDA	28676677

MIM	HGNC	e!Ensembl
143010	4962	ENSG00000204592

Protein

UniProt ID

P13747

Protein name

HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain E (sHLA-E)]

Protein function

Non-classical major histocompatibility class Ib molecule involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglobulin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molecules (V

PDB

1KPR , 1KTL , 1MHE , 2ESV , 3AM8 , 3BZE , 3BZF , 3CDG , 3CII , 5W1V , 5W1W , 6GGM , 6GH1 , 6GH4 , 6GHN , 6GL1 , 6ZKW , 6ZKX , 6ZKY , 6ZKZ , 7BH8 , 7NDQ , 7NDT , 7NDU , 7P49 , 7P4B , 8QFY , 8RLT , 8RLU , 8RLV

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00129	MHC_I	22 → 200	Class I Histocompatibility antigen, domains alpha 1 and 2	Domain
PF07654	C1-set	207 → 287	Immunoglobulin C1-set domain	Domain
PF06623	MHC_I_C	334 → 355	MHC_I C-terminus	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in secretory endometrial cells during pregnancy (at protein level). The expression in nonlymphoid tissues is restricted to endothelial cells from all types of vessels, including arteries, veins, capillaries, and lymphatics (a

Sequence

MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND
AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH
GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY
LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ
DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ
PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL

Sequence length

358

Interactions

View interactions

	KEGG		Reactome
	Endocytosis Phagosome Cellular senescence Cell adhesion molecules Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Human cytomegalovirus infection Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Viral carcinogenesis Autoimmune thyroid disease Allograft rejection Graft-versus-host disease Viral myocarditis		ER-Phagosome pathway Endosomal/Vacuolar pathway Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions DAP12 signaling Interferon gamma signaling Interferon alpha/beta signaling Antigen Presentation: Folding, assembly and peptide loading of class I MHC

HLA-E (major histocompatibility complex, class I, E)