Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3106
Gene name Gene Name - the full gene name approved by the HGNC.	Major histocompatibility complex, class I, B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HLA-B
Synonyms (NCBI Gene) Gene synonyms aliases	AS, B-4901, HLAB
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p21.33
Summary Summary of gene provided in NCBI Entrez Gene.	HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the

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miRTarBase ID	miRNA	Experiments	Reference
MIRT039965	hsa-miR-615-3p	CLASH	23622248
MIRT716701	hsa-miR-1306-5p	HITS-CLIP	19536157
MIRT716700	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT716699	hsa-miR-626	HITS-CLIP	19536157
MIRT716698	hsa-miR-6876-3p	HITS-CLIP	19536157
MIRT716697	hsa-miR-4656	HITS-CLIP	19536157
MIRT716696	hsa-miR-6829-5p	HITS-CLIP	19536157
MIRT716695	hsa-miR-4492	HITS-CLIP	19536157
MIRT716694	hsa-miR-4498	HITS-CLIP	19536157
MIRT716693	hsa-miR-5001-5p	HITS-CLIP	19536157
MIRT716692	hsa-miR-762	HITS-CLIP	19536157
MIRT716691	hsa-miR-4675	HITS-CLIP	19536157
MIRT716690	hsa-miR-4741	HITS-CLIP	19536157
MIRT716689	hsa-miR-6756-5p	HITS-CLIP	19536157
MIRT716688	hsa-miR-6766-5p	HITS-CLIP	19536157
MIRT716687	hsa-miR-541-3p	HITS-CLIP	19536157
MIRT716686	hsa-miR-654-5p	HITS-CLIP	19536157
MIRT716685	hsa-miR-6895-3p	HITS-CLIP	19536157
MIRT716684	hsa-miR-593-3p	HITS-CLIP	19536157
MIRT716683	hsa-miR-4417	HITS-CLIP	19536157
MIRT716682	hsa-miR-1587	HITS-CLIP	19536157
MIRT716681	hsa-miR-3620-5p	HITS-CLIP	19536157
MIRT716680	hsa-miR-6818-3p	HITS-CLIP	19536157
MIRT486968	hsa-miR-495-5p	PAR-CLIP	23592263
MIRT486966	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT486967	hsa-miR-6750-5p	PAR-CLIP	23592263
MIRT486965	hsa-miR-6822-5p	PAR-CLIP	23592263
MIRT486964	hsa-miR-9500	PAR-CLIP	23592263
MIRT486963	hsa-miR-10b-3p	PAR-CLIP	23592263
MIRT486962	hsa-miR-936	PAR-CLIP	23592263
MIRT486961	hsa-miR-199a-3p	PAR-CLIP	23592263
MIRT486960	hsa-miR-199b-3p	PAR-CLIP	23592263
MIRT486959	hsa-miR-3129-5p	PAR-CLIP	23592263
MIRT486958	hsa-miR-548ao-5p	PAR-CLIP	23592263
MIRT486957	hsa-miR-548ax	PAR-CLIP	23592263
MIRT486956	hsa-miR-4660	PAR-CLIP	23592263
MIRT392124	hsa-miR-3653-3p	PAR-CLIP	23592263
MIRT486955	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT486954	hsa-miR-7156-3p	PAR-CLIP	23592263
MIRT486953	hsa-miR-1301-3p	PAR-CLIP	23592263
MIRT486952	hsa-miR-5047	PAR-CLIP	23592263
MIRT486951	hsa-miR-30a-3p	PAR-CLIP	23592263
MIRT486950	hsa-miR-30d-3p	PAR-CLIP	23592263
MIRT486949	hsa-miR-30e-3p	PAR-CLIP	23592263
MIRT716701	hsa-miR-1306-5p	HITS-CLIP	19536157
MIRT716700	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT716699	hsa-miR-626	HITS-CLIP	19536157
MIRT716698	hsa-miR-6876-3p	HITS-CLIP	19536157
MIRT716697	hsa-miR-4656	HITS-CLIP	19536157
MIRT716696	hsa-miR-6829-5p	HITS-CLIP	19536157
MIRT716695	hsa-miR-4492	HITS-CLIP	19536157
MIRT716694	hsa-miR-4498	HITS-CLIP	19536157
MIRT716693	hsa-miR-5001-5p	HITS-CLIP	19536157
MIRT716692	hsa-miR-762	HITS-CLIP	19536157
MIRT716691	hsa-miR-4675	HITS-CLIP	19536157
MIRT716690	hsa-miR-4741	HITS-CLIP	19536157
MIRT716689	hsa-miR-6756-5p	HITS-CLIP	19536157
MIRT716688	hsa-miR-6766-5p	HITS-CLIP	19536157
MIRT716687	hsa-miR-541-3p	HITS-CLIP	19536157
MIRT716686	hsa-miR-654-5p	HITS-CLIP	19536157
MIRT716685	hsa-miR-6895-3p	HITS-CLIP	19536157
MIRT716684	hsa-miR-593-3p	HITS-CLIP	19536157
MIRT716683	hsa-miR-4417	HITS-CLIP	19536157
MIRT716682	hsa-miR-1587	HITS-CLIP	19536157
MIRT716681	hsa-miR-3620-5p	HITS-CLIP	19536157
MIRT716680	hsa-miR-6818-3p	HITS-CLIP	19536157
MIRT486968	hsa-miR-495-5p	PAR-CLIP	23592263
MIRT486966	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT486967	hsa-miR-6750-5p	PAR-CLIP	23592263
MIRT486965	hsa-miR-6822-5p	PAR-CLIP	23592263
MIRT486964	hsa-miR-9500	PAR-CLIP	23592263
MIRT486963	hsa-miR-10b-3p	PAR-CLIP	23592263
MIRT486962	hsa-miR-936	PAR-CLIP	23592263
MIRT486961	hsa-miR-199a-3p	PAR-CLIP	23592263
MIRT486960	hsa-miR-199b-3p	PAR-CLIP	23592263
MIRT486959	hsa-miR-3129-5p	PAR-CLIP	23592263
MIRT486958	hsa-miR-548ao-5p	PAR-CLIP	23592263
MIRT486957	hsa-miR-548ax	PAR-CLIP	23592263
MIRT486956	hsa-miR-4660	PAR-CLIP	23592263
MIRT392124	hsa-miR-3653-3p	PAR-CLIP	23592263
MIRT486955	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT486954	hsa-miR-7156-3p	PAR-CLIP	23592263
MIRT486953	hsa-miR-1301-3p	PAR-CLIP	23592263
MIRT486952	hsa-miR-5047	PAR-CLIP	23592263
MIRT486951	hsa-miR-30a-3p	PAR-CLIP	23592263
MIRT486950	hsa-miR-30d-3p	PAR-CLIP	23592263
MIRT486949	hsa-miR-30e-3p	PAR-CLIP	23592263
MIRT1048287	hsa-miR-3185	CLIP-seq
MIRT1048288	hsa-miR-4719	CLIP-seq
MIRT1549513	hsa-miR-103b	CLIP-seq
MIRT1549514	hsa-miR-1301	CLIP-seq
MIRT1549515	hsa-miR-148a	CLIP-seq
MIRT1549516	hsa-miR-148b	CLIP-seq
MIRT1549517	hsa-miR-152	CLIP-seq
MIRT1549518	hsa-miR-23a	CLIP-seq
MIRT1549519	hsa-miR-23b	CLIP-seq
MIRT1549520	hsa-miR-23c	CLIP-seq
MIRT1549521	hsa-miR-3146	CLIP-seq
MIRT1549522	hsa-miR-3166	CLIP-seq
MIRT1549523	hsa-miR-3653	CLIP-seq
MIRT1549524	hsa-miR-3672	CLIP-seq
MIRT1549525	hsa-miR-4311	CLIP-seq
MIRT1549526	hsa-miR-4708-5p	CLIP-seq
MIRT1549527	hsa-miR-548p	CLIP-seq
MIRT1549528	hsa-miR-561	CLIP-seq
MIRT1549518	hsa-miR-23a	CLIP-seq
MIRT1549519	hsa-miR-23b	CLIP-seq
MIRT1549520	hsa-miR-23c	CLIP-seq
MIRT1549521	hsa-miR-3146	CLIP-seq
MIRT1549514	hsa-miR-1301	CLIP-seq
MIRT1549515	hsa-miR-148a	CLIP-seq
MIRT1549516	hsa-miR-148b	CLIP-seq
MIRT1549517	hsa-miR-152	CLIP-seq
MIRT2010971	hsa-miR-181a	CLIP-seq
MIRT2010972	hsa-miR-181b	CLIP-seq
MIRT2010973	hsa-miR-181c	CLIP-seq
MIRT2010974	hsa-miR-181d	CLIP-seq
MIRT2010975	hsa-miR-2467-5p	CLIP-seq
MIRT1549523	hsa-miR-3653	CLIP-seq
MIRT2010976	hsa-miR-3942-3p	CLIP-seq
MIRT2010977	hsa-miR-4262	CLIP-seq
MIRT1549525	hsa-miR-4311	CLIP-seq
MIRT1549526	hsa-miR-4708-5p	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT2243211	hsa-miR-1273f	CLIP-seq
MIRT2010971	hsa-miR-181a	CLIP-seq
MIRT2010972	hsa-miR-181b	CLIP-seq
MIRT2010973	hsa-miR-181c	CLIP-seq
MIRT2010974	hsa-miR-181d	CLIP-seq
MIRT2243212	hsa-miR-224	CLIP-seq
MIRT1549518	hsa-miR-23a	CLIP-seq
MIRT1549519	hsa-miR-23b	CLIP-seq
MIRT1549520	hsa-miR-23c	CLIP-seq
MIRT2010975	hsa-miR-2467-5p	CLIP-seq
MIRT1549521	hsa-miR-3146	CLIP-seq
MIRT1549522	hsa-miR-3166	CLIP-seq
MIRT2243213	hsa-miR-3616-5p	CLIP-seq
MIRT2243214	hsa-miR-3647-5p	CLIP-seq
MIRT1549524	hsa-miR-3672	CLIP-seq
MIRT2243215	hsa-miR-371-5p	CLIP-seq
MIRT2243216	hsa-miR-371b-5p	CLIP-seq
MIRT2010977	hsa-miR-4262	CLIP-seq
MIRT2243217	hsa-miR-4635	CLIP-seq
MIRT1048288	hsa-miR-4719	CLIP-seq
MIRT2243218	hsa-miR-4756-3p	CLIP-seq
MIRT1549528	hsa-miR-561	CLIP-seq
MIRT2243219	hsa-miR-573	CLIP-seq
MIRT2243220	hsa-miR-593	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT1549518	hsa-miR-23a	CLIP-seq
MIRT1549519	hsa-miR-23b	CLIP-seq
MIRT1549520	hsa-miR-23c	CLIP-seq
MIRT2010975	hsa-miR-2467-5p	CLIP-seq
MIRT1549521	hsa-miR-3146	CLIP-seq
MIRT1549522	hsa-miR-3166	CLIP-seq
MIRT1549525	hsa-miR-4311	CLIP-seq
MIRT2243217	hsa-miR-4635	CLIP-seq
MIRT1549526	hsa-miR-4708-5p	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT1549513	hsa-miR-103b	CLIP-seq
MIRT2429606	hsa-miR-125a-3p	CLIP-seq
MIRT1549514	hsa-miR-1301	CLIP-seq
MIRT1549515	hsa-miR-148a	CLIP-seq
MIRT1549516	hsa-miR-148b	CLIP-seq
MIRT1549517	hsa-miR-152	CLIP-seq
MIRT2010971	hsa-miR-181a	CLIP-seq
MIRT2010972	hsa-miR-181b	CLIP-seq
MIRT2010973	hsa-miR-181c	CLIP-seq
MIRT2010974	hsa-miR-181d	CLIP-seq
MIRT2429607	hsa-miR-298	CLIP-seq
MIRT2429608	hsa-miR-3121-5p	CLIP-seq
MIRT1549523	hsa-miR-3653	CLIP-seq
MIRT2429609	hsa-miR-3678-3p	CLIP-seq
MIRT2429610	hsa-miR-3934	CLIP-seq
MIRT2010976	hsa-miR-3942-3p	CLIP-seq
MIRT2010977	hsa-miR-4262	CLIP-seq
MIRT2429611	hsa-miR-4714-3p	CLIP-seq
MIRT2429612	hsa-miR-539	CLIP-seq
MIRT1549527	hsa-miR-548p	CLIP-seq
MIRT1549528	hsa-miR-561	CLIP-seq
MIRT2429613	hsa-miR-570	CLIP-seq
MIRT2429614	hsa-miR-580	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT2429615	hsa-miR-764	CLIP-seq
MIRT2429606	hsa-miR-125a-3p	CLIP-seq
MIRT2437601	hsa-miR-128	CLIP-seq
MIRT2437602	hsa-miR-1292	CLIP-seq
MIRT2010971	hsa-miR-181a	CLIP-seq
MIRT2010972	hsa-miR-181b	CLIP-seq
MIRT2010973	hsa-miR-181c	CLIP-seq
MIRT2010974	hsa-miR-181d	CLIP-seq
MIRT1549518	hsa-miR-23a	CLIP-seq
MIRT1549519	hsa-miR-23b	CLIP-seq
MIRT1549520	hsa-miR-23c	CLIP-seq
MIRT2437603	hsa-miR-27a	CLIP-seq
MIRT2437604	hsa-miR-27b	CLIP-seq
MIRT2429607	hsa-miR-298	CLIP-seq
MIRT2429608	hsa-miR-3121-5p	CLIP-seq
MIRT2437605	hsa-miR-3138	CLIP-seq
MIRT1549521	hsa-miR-3146	CLIP-seq
MIRT2437606	hsa-miR-3150a-3p	CLIP-seq
MIRT1549522	hsa-miR-3166	CLIP-seq
MIRT2437607	hsa-miR-3175	CLIP-seq
MIRT2429609	hsa-miR-3678-3p	CLIP-seq
MIRT2429610	hsa-miR-3934	CLIP-seq
MIRT2437608	hsa-miR-4261	CLIP-seq
MIRT2010977	hsa-miR-4262	CLIP-seq
MIRT2437609	hsa-miR-4310	CLIP-seq
MIRT1549525	hsa-miR-4311	CLIP-seq
MIRT2437610	hsa-miR-4457	CLIP-seq
MIRT2437611	hsa-miR-4471	CLIP-seq
MIRT2437612	hsa-miR-4496	CLIP-seq
MIRT2437613	hsa-miR-4667-5p	CLIP-seq
MIRT2437614	hsa-miR-4700-5p	CLIP-seq
MIRT1549526	hsa-miR-4708-5p	CLIP-seq
MIRT2437615	hsa-miR-4731-3p	CLIP-seq
MIRT2437616	hsa-miR-4801	CLIP-seq
MIRT2437617	hsa-miR-541	CLIP-seq
MIRT2243220	hsa-miR-593	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT2429615	hsa-miR-764	CLIP-seq
MIRT2437618	hsa-miR-939	CLIP-seq
MIRT2429606	hsa-miR-125a-3p	CLIP-seq
MIRT2010971	hsa-miR-181a	CLIP-seq
MIRT2010972	hsa-miR-181b	CLIP-seq
MIRT2010973	hsa-miR-181c	CLIP-seq
MIRT2010974	hsa-miR-181d	CLIP-seq
MIRT2243212	hsa-miR-224	CLIP-seq
MIRT2010975	hsa-miR-2467-5p	CLIP-seq
MIRT2429607	hsa-miR-298	CLIP-seq
MIRT2429608	hsa-miR-3121-5p	CLIP-seq
MIRT1048287	hsa-miR-3185	CLIP-seq
MIRT2243213	hsa-miR-3616-5p	CLIP-seq
MIRT2243214	hsa-miR-3647-5p	CLIP-seq
MIRT2429609	hsa-miR-3678-3p	CLIP-seq
MIRT2429610	hsa-miR-3934	CLIP-seq
MIRT2010977	hsa-miR-4262	CLIP-seq
MIRT1549525	hsa-miR-4311	CLIP-seq
MIRT2243217	hsa-miR-4635	CLIP-seq
MIRT1549526	hsa-miR-4708-5p	CLIP-seq
MIRT1048288	hsa-miR-4719	CLIP-seq
MIRT2243219	hsa-miR-573	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT2429615	hsa-miR-764	CLIP-seq
MIRT2429606	hsa-miR-125a-3p	CLIP-seq
MIRT2010971	hsa-miR-181a	CLIP-seq
MIRT2010972	hsa-miR-181b	CLIP-seq
MIRT2010973	hsa-miR-181c	CLIP-seq
MIRT2010974	hsa-miR-181d	CLIP-seq
MIRT2429607	hsa-miR-298	CLIP-seq
MIRT2429608	hsa-miR-3121-5p	CLIP-seq
MIRT2429609	hsa-miR-3678-3p	CLIP-seq
MIRT2429610	hsa-miR-3934	CLIP-seq
MIRT2010977	hsa-miR-4262	CLIP-seq
MIRT1549525	hsa-miR-4311	CLIP-seq
MIRT1549526	hsa-miR-4708-5p	CLIP-seq
MIRT2010978	hsa-miR-642b	CLIP-seq
MIRT2429615	hsa-miR-764	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
CIITA	Activation	11053628
HIVEP2	Unknown	1409593
MYC	Activation	8206526
MYCN	Unknown	8895520

Show/Hide all(60)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0001916	Process	Positive regulation of T cell mediated cytotoxicity	IBA
GO:0001916	Process	Positive regulation of T cell mediated cytotoxicity	IDA	2420472
GO:0002250	Process	Adaptive immune response	IEA
GO:0002376	Process	Immune system process	IEA
GO:0002474	Process	Antigen processing and presentation of peptide antigen via MHC class I	IEA
GO:0002476	Process	Antigen processing and presentation of endogenous peptide antigen via MHC class Ib	IBA
GO:0002486	Process	Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	IBA
GO:0002486	Process	Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	IDA	22031944
GO:0002667	Process	Regulation of T cell anergy	IMP	20008523
GO:0005102	Function	Signaling receptor binding	IBA
GO:0005102	Function	Signaling receptor binding	IPI	8046333, 20008523
GO:0005515	Function	Protein binding	IPI	12853576, 19858347, 24018270, 26439010, 27649529, 28546555
GO:0005615	Component	Extracellular space	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA	20946353
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IDA	20946353
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	NAS	518865, 2715640, 8420828, 8976183
GO:0005886	Component	Plasma membrane	TAS
GO:0006952	Process	Defense response	TAS	3011411
GO:0006955	Process	Immune response	IBA
GO:0006955	Process	Immune response	IEA
GO:0006955	Process	Immune response	IMP	22321387
GO:0006955	Process	Immune response	NAS	518865, 2715640, 8420828, 8976183
GO:0009897	Component	External side of plasma membrane	IBA
GO:0009986	Component	Cell surface	HDA	19581412
GO:0009986	Component	Cell surface	IDA	9754572, 22031944
GO:0009986	Component	Cell surface	IEA
GO:0012507	Component	ER to Golgi transport vesicle membrane	IEA
GO:0012507	Component	ER to Golgi transport vesicle membrane	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	3011411
GO:0016045	Process	Detection of bacterium	IMP	22321387
GO:0019882	Process	Antigen processing and presentation	IEA
GO:0030667	Component	Secretory granule membrane	TAS
GO:0030670	Component	Phagocytic vesicle membrane	IEA
GO:0030670	Component	Phagocytic vesicle membrane	TAS
GO:0031901	Component	Early endosome membrane	IEA
GO:0031901	Component	Early endosome membrane	TAS
GO:0032655	Process	Regulation of interleukin-12 production	IMP	20008523
GO:0032675	Process	Regulation of interleukin-6 production	IMP	20008523
GO:0042270	Process	Protection from natural killer cell mediated cytotoxicity	IDA	2784569, 8046333, 18502829
GO:0042605	Function	Peptide antigen binding	IBA
GO:0042605	Function	Peptide antigen binding	IDA	22031944, 23646949
GO:0042612	Component	MHC class I protein complex	IDA	22031944
GO:0042612	Component	MHC class I protein complex	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0046977	Function	TAP binding	IDA	8617941
GO:0046977	Function	TAP binding	IDA	8617941
GO:0051087	Function	Protein-folding chaperone binding	IPI	15056662
GO:0055038	Component	Recycling endosome membrane	IEA
GO:0055038	Component	Recycling endosome membrane	TAS
GO:0070062	Component	Extracellular exosome	HDA	12519789, 19056867, 19199708, 20458337
GO:0098553	Component	Lumenal side of endoplasmic reticulum membrane	IEA
GO:0098553	Component	Lumenal side of endoplasmic reticulum membrane	TAS
GO:2001198	Process	Regulation of dendritic cell differentiation	IMP	20008523

MIM	HGNC	e!Ensembl
142830	4932	ENSG00000234745

Protein

UniProt ID

P01889

Protein name

HLA class I histocompatibility antigen, B alpha chain (Human leukocyte antigen B) (HLA-B)

Protein function

Antigen-presenting major histocompatibility complex class I (MHCI) molecule. In complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived peptides on antigen-presenting cells for recognition by alpha-beta T cell receptor (

PDB

1A1M , 1A1N , 1A1O , 1A9B , 1A9E , 1AGB , 1AGC , 1AGD , 1AGE , 1AGF , 1CG9 , 1E27 , 1E28 , 1HSA , 1JGD , 1JGE , 1K5N , 1M05 , 1M6O , 1MI5 , 1N2R , 1OF2 , 1OGT , 1SYS , 1SYV , 1UXS , 1UXW , 1W0V , 1W0W , 1XH3 , 1XR8 , 1XR9 , 1ZHK , 1ZHL , 1ZSD , 2A83 , 2AK4 , 2AXF , 2AXG , 2BSR , 2BSS , 2BST , 2BVO , 2BVP , 2BVQ , 2H6P , 2HJL , 2NW3 , 2NX5 , 2RFX , 2YPK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00129	MHC_I	25 → 203	Class I Histocompatibility antigen, domains alpha 1 and 2	Domain
PF07654	C1-set	211 → 290	Immunoglobulin C1-set domain	Domain
PF06623	MHC_I_C	337 → 362	MHC_I C-terminus	Family

Sequence

MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF
DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ
SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR
RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT
WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP
SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL
TA

Sequence length

362

Interactions

View interactions

	KEGG		Reactome
	Endocytosis Phagosome Cellular senescence Cell adhesion molecules Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Human cytomegalovirus infection Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Viral carcinogenesis Autoimmune thyroid disease Allograft rejection Graft-versus-host disease Viral myocarditis		ER-Phagosome pathway Endosomal/Vacuolar pathway Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions Neutrophil degranulation Interferon gamma signaling Interferon alpha/beta signaling Antigen Presentation: Folding, assembly and peptide loading of class I MHC

HLA-B (major histocompatibility complex, class I, B)