Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	310
Gene name Gene Name - the full gene name approved by the HGNC.	Annexin A7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ANXA7
Synonyms (NCBI Gene) Gene synonyms aliases	ANX7, SNX, SYNEXIN
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q22.2
Summary Summary of gene provided in NCBI Entrez Gene.	Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and

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miRTarBase ID	miRNA	Experiments	Reference
MIRT023283	hsa-miR-122-5p	Proteomics	21750653
MIRT048217	hsa-miR-196a-5p	CLASH	23622248
MIRT043161	hsa-miR-324-5p	CLASH	23622248
MIRT439134	hsa-miR-10b-5p	3'LIFE	25074381
MIRT439134	hsa-miR-10b-5p	3'LIFE	25074381
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT786610	hsa-miR-124	CLIP-seq
MIRT786611	hsa-miR-1252	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT786616	hsa-miR-3194-3p	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT786618	hsa-miR-3665	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786620	hsa-miR-3910	CLIP-seq
MIRT786621	hsa-miR-4317	CLIP-seq
MIRT786622	hsa-miR-506	CLIP-seq
MIRT786623	hsa-miR-548n	CLIP-seq
MIRT786624	hsa-miR-570	CLIP-seq
MIRT786625	hsa-miR-616	CLIP-seq
MIRT786626	hsa-miR-657	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786627	hsa-miR-4328	CLIP-seq
MIRT786628	hsa-miR-4672	CLIP-seq
MIRT786629	hsa-miR-603	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT2172439	hsa-miR-4272	CLIP-seq
MIRT786627	hsa-miR-4328	CLIP-seq
MIRT786628	hsa-miR-4672	CLIP-seq
MIRT2172440	hsa-miR-548a-5p	CLIP-seq
MIRT2172441	hsa-miR-548ab	CLIP-seq
MIRT2172442	hsa-miR-548ak	CLIP-seq
MIRT2172443	hsa-miR-548b-5p	CLIP-seq
MIRT2172444	hsa-miR-548c-5p	CLIP-seq
MIRT2172445	hsa-miR-548d-5p	CLIP-seq
MIRT2172446	hsa-miR-548h	CLIP-seq
MIRT2172447	hsa-miR-548i	CLIP-seq
MIRT2172448	hsa-miR-548j	CLIP-seq
MIRT2172449	hsa-miR-548k	CLIP-seq
MIRT2172450	hsa-miR-548l	CLIP-seq
MIRT2172451	hsa-miR-548w	CLIP-seq
MIRT2172452	hsa-miR-548y	CLIP-seq
MIRT2172453	hsa-miR-559	CLIP-seq
MIRT786624	hsa-miR-570	CLIP-seq
MIRT786629	hsa-miR-603	CLIP-seq
MIRT2172454	hsa-miR-944	CLIP-seq
MIRT2384269	hsa-miR-3919	CLIP-seq
MIRT2384270	hsa-miR-4679	CLIP-seq
MIRT2384271	hsa-miR-4756-3p	CLIP-seq
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT2475367	hsa-miR-1183	CLIP-seq
MIRT786610	hsa-miR-124	CLIP-seq
MIRT786611	hsa-miR-1252	CLIP-seq
MIRT2475368	hsa-miR-1273f	CLIP-seq
MIRT2475369	hsa-miR-135a	CLIP-seq
MIRT2475370	hsa-miR-135b	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT2475371	hsa-miR-143	CLIP-seq
MIRT2475372	hsa-miR-190	CLIP-seq
MIRT2475373	hsa-miR-190b	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT2475374	hsa-miR-200b	CLIP-seq
MIRT2475375	hsa-miR-200c	CLIP-seq
MIRT2475376	hsa-miR-219-5p	CLIP-seq
MIRT2475377	hsa-miR-297	CLIP-seq
MIRT2475378	hsa-miR-299-3p	CLIP-seq
MIRT2475379	hsa-miR-299-5p	CLIP-seq
MIRT2475380	hsa-miR-3064-3p	CLIP-seq
MIRT2475381	hsa-miR-3119	CLIP-seq
MIRT2475382	hsa-miR-3123	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT2475383	hsa-miR-3149	CLIP-seq
MIRT2475384	hsa-miR-3163	CLIP-seq
MIRT2475385	hsa-miR-3190	CLIP-seq
MIRT786616	hsa-miR-3194-3p	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT2475386	hsa-miR-3662	CLIP-seq
MIRT786618	hsa-miR-3665	CLIP-seq
MIRT2475387	hsa-miR-3668	CLIP-seq
MIRT2475388	hsa-miR-3689a-5p	CLIP-seq
MIRT2475389	hsa-miR-3689b	CLIP-seq
MIRT2475390	hsa-miR-3689e	CLIP-seq
MIRT2475391	hsa-miR-3689f	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786620	hsa-miR-3910	CLIP-seq
MIRT2475392	hsa-miR-3923	CLIP-seq
MIRT2475393	hsa-miR-3925-5p	CLIP-seq
MIRT2475394	hsa-miR-3978	CLIP-seq
MIRT2475395	hsa-miR-4282	CLIP-seq
MIRT2475396	hsa-miR-4289	CLIP-seq
MIRT2475397	hsa-miR-429	CLIP-seq
MIRT786621	hsa-miR-4317	CLIP-seq
MIRT2475398	hsa-miR-4423-3p	CLIP-seq
MIRT2475399	hsa-miR-4445	CLIP-seq
MIRT2475400	hsa-miR-4452	CLIP-seq
MIRT2475401	hsa-miR-4491	CLIP-seq
MIRT2475402	hsa-miR-4495	CLIP-seq
MIRT2475403	hsa-miR-4657	CLIP-seq
MIRT2475404	hsa-miR-4693-5p	CLIP-seq
MIRT2475405	hsa-miR-4698	CLIP-seq
MIRT2475406	hsa-miR-4708-5p	CLIP-seq
MIRT2475407	hsa-miR-4732-5p	CLIP-seq
MIRT2475408	hsa-miR-4738-3p	CLIP-seq
MIRT2475409	hsa-miR-4770	CLIP-seq
MIRT2475410	hsa-miR-4777-5p	CLIP-seq
MIRT2475411	hsa-miR-4782-3p	CLIP-seq
MIRT2475412	hsa-miR-493	CLIP-seq
MIRT786622	hsa-miR-506	CLIP-seq
MIRT2475413	hsa-miR-508-3p	CLIP-seq
MIRT2475414	hsa-miR-518d-5p	CLIP-seq
MIRT2475415	hsa-miR-519b-5p	CLIP-seq
MIRT2475416	hsa-miR-519c-5p	CLIP-seq
MIRT2475417	hsa-miR-520c-5p	CLIP-seq
MIRT2475418	hsa-miR-520d-5p	CLIP-seq
MIRT2475419	hsa-miR-524-5p	CLIP-seq
MIRT2475420	hsa-miR-526a	CLIP-seq
MIRT2475421	hsa-miR-548m	CLIP-seq
MIRT2475422	hsa-miR-567	CLIP-seq
MIRT2475423	hsa-miR-576-3p	CLIP-seq
MIRT786625	hsa-miR-616	CLIP-seq
MIRT2475424	hsa-miR-628-3p	CLIP-seq
MIRT786626	hsa-miR-657	CLIP-seq
MIRT2172454	hsa-miR-944	CLIP-seq
MIRT786608	hsa-miR-10a	CLIP-seq
MIRT786609	hsa-miR-10b	CLIP-seq
MIRT2475367	hsa-miR-1183	CLIP-seq
MIRT786610	hsa-miR-124	CLIP-seq
MIRT786611	hsa-miR-1252	CLIP-seq
MIRT2475368	hsa-miR-1273f	CLIP-seq
MIRT2475369	hsa-miR-135a	CLIP-seq
MIRT2475370	hsa-miR-135b	CLIP-seq
MIRT786612	hsa-miR-137	CLIP-seq
MIRT2475371	hsa-miR-143	CLIP-seq
MIRT2475372	hsa-miR-190	CLIP-seq
MIRT2475373	hsa-miR-190b	CLIP-seq
MIRT786613	hsa-miR-19a	CLIP-seq
MIRT786614	hsa-miR-19b	CLIP-seq
MIRT2475374	hsa-miR-200b	CLIP-seq
MIRT2475375	hsa-miR-200c	CLIP-seq
MIRT2475376	hsa-miR-219-5p	CLIP-seq
MIRT2475377	hsa-miR-297	CLIP-seq
MIRT2475378	hsa-miR-299-3p	CLIP-seq
MIRT2475379	hsa-miR-299-5p	CLIP-seq
MIRT2475380	hsa-miR-3064-3p	CLIP-seq
MIRT2475381	hsa-miR-3119	CLIP-seq
MIRT2475382	hsa-miR-3123	CLIP-seq
MIRT786615	hsa-miR-3145-3p	CLIP-seq
MIRT2475383	hsa-miR-3149	CLIP-seq
MIRT2475384	hsa-miR-3163	CLIP-seq
MIRT2475385	hsa-miR-3190	CLIP-seq
MIRT786616	hsa-miR-3194-3p	CLIP-seq
MIRT786617	hsa-miR-323-3p	CLIP-seq
MIRT2475386	hsa-miR-3662	CLIP-seq
MIRT786618	hsa-miR-3665	CLIP-seq
MIRT2475387	hsa-miR-3668	CLIP-seq
MIRT2475388	hsa-miR-3689a-5p	CLIP-seq
MIRT2475389	hsa-miR-3689b	CLIP-seq
MIRT2475390	hsa-miR-3689e	CLIP-seq
MIRT2475391	hsa-miR-3689f	CLIP-seq
MIRT786619	hsa-miR-3714	CLIP-seq
MIRT786620	hsa-miR-3910	CLIP-seq
MIRT2475392	hsa-miR-3923	CLIP-seq
MIRT2475393	hsa-miR-3925-5p	CLIP-seq
MIRT2475394	hsa-miR-3978	CLIP-seq
MIRT2475395	hsa-miR-4282	CLIP-seq
MIRT2475396	hsa-miR-4289	CLIP-seq
MIRT2475397	hsa-miR-429	CLIP-seq
MIRT786621	hsa-miR-4317	CLIP-seq
MIRT2475398	hsa-miR-4423-3p	CLIP-seq
MIRT2475399	hsa-miR-4445	CLIP-seq
MIRT2475400	hsa-miR-4452	CLIP-seq
MIRT2475401	hsa-miR-4491	CLIP-seq
MIRT2475402	hsa-miR-4495	CLIP-seq
MIRT2475403	hsa-miR-4657	CLIP-seq
MIRT2475404	hsa-miR-4693-5p	CLIP-seq
MIRT2475405	hsa-miR-4698	CLIP-seq
MIRT2475406	hsa-miR-4708-5p	CLIP-seq
MIRT2475407	hsa-miR-4732-5p	CLIP-seq
MIRT2475408	hsa-miR-4738-3p	CLIP-seq
MIRT2475409	hsa-miR-4770	CLIP-seq
MIRT2475410	hsa-miR-4777-5p	CLIP-seq
MIRT2475411	hsa-miR-4782-3p	CLIP-seq
MIRT2475412	hsa-miR-493	CLIP-seq
MIRT786622	hsa-miR-506	CLIP-seq
MIRT2475413	hsa-miR-508-3p	CLIP-seq
MIRT2475414	hsa-miR-518d-5p	CLIP-seq
MIRT2475415	hsa-miR-519b-5p	CLIP-seq
MIRT2475416	hsa-miR-519c-5p	CLIP-seq
MIRT2475417	hsa-miR-520c-5p	CLIP-seq
MIRT2475418	hsa-miR-520d-5p	CLIP-seq
MIRT2475419	hsa-miR-524-5p	CLIP-seq
MIRT2475420	hsa-miR-526a	CLIP-seq
MIRT2475421	hsa-miR-548m	CLIP-seq
MIRT2475422	hsa-miR-567	CLIP-seq
MIRT2475423	hsa-miR-576-3p	CLIP-seq
MIRT786625	hsa-miR-616	CLIP-seq
MIRT2475424	hsa-miR-628-3p	CLIP-seq
MIRT786626	hsa-miR-657	CLIP-seq
MIRT2172454	hsa-miR-944	CLIP-seq

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001786	Function	Phosphatidylserine binding	IBA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005178	Function	Integrin binding	IPI	24007983
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	9268363, 12445460, 17699613
GO:0005544	Function	Calcium-dependent phospholipid binding	IBA
GO:0005544	Function	Calcium-dependent phospholipid binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	10672515
GO:0005737	Component	Cytoplasm	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	10672515
GO:0005886	Component	Plasma membrane	IBA
GO:0006914	Process	Autophagy	IMP	24007983
GO:0010629	Process	Negative regulation of gene expression	IMP	24007983
GO:0012506	Component	Vesicle membrane	IBA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030855	Process	Epithelial cell differentiation	IEP	21492153
GO:0031012	Component	Extracellular matrix	HDA	25037231
GO:0042584	Component	Chromaffin granule membrane	IDA	9268363
GO:0048306	Function	Calcium-dependent protein binding	IPI	12445460
GO:0051592	Process	Response to calcium ion	IEA
GO:0061025	Process	Membrane fusion	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 20458337, 23533145
GO:1904627	Process	Response to phorbol 13-acetate 12-myristate	IEA

MIM	HGNC	e!Ensembl
186360	545	ENSG00000138279

Protein

UniProt ID

P20073

Protein name

Annexin A7 (Annexin VII) (Annexin-7) (Synexin)

Protein function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

PDB

8W5S

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00191	Annexin	189 → 254	Annexin	Family
PF00191	Annexin	261 → 326	Annexin	Family
PF00191	Annexin	344 → 410	Annexin	Family
PF00191	Annexin	420 → 485	Annexin	Family

Tissue specificity

TISSUE SPECIFICITY: Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta. {ECO:0000269|PubMed:1825209}.

Sequence

MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY
PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV
PLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIR
PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK
SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ
SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD
ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF
FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR
LLLAIVGQ

Sequence length

488

Interactions

View interactions

	KEGG
	Amyotrophic lateral sclerosis

ANXA7 (annexin A7)