Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
30845
Gene name Gene Name - the full gene name approved by the HGNC.
EH domain containing 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
EHD3
Synonyms (NCBI Gene) Gene synonyms aliases
PAST3
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p23.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025667 hsa-miR-7-5p Microarray 19073608
MIRT607977 hsa-miR-3664-5p HITS-CLIP 19536157
MIRT607976 hsa-miR-4522 HITS-CLIP 19536157
MIRT450028 hsa-miR-4524a-3p HITS-CLIP 19536157
MIRT504484 hsa-miR-6867-5p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0001881 Process Receptor recycling IMP 21791287
GO:0003676 Function Nucleic acid binding TAS 10673336
GO:0005509 Function Calcium ion binding IEA
GO:0005515 Function Protein binding IPI 15020713, 17233914, 19864458, 20489164, 26226295, 27189942, 28514442, 32296183, 33961781
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
605891 3244 ENSG00000013016
Protein
UniProt ID Q9NZN3
Protein name EH domain-containing protein 3 (PAST homolog 3)
Protein function ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). In vitro causes tubulation of endocytic membranes (PubMed:24019528). Binding to phosphatidic acid induces its membrane tubu
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16880 EHD_N 24 56 N-terminal EH-domain containing protein Family
PF00350 Dynamin_N 61 221 Dynamin family Domain
PF18150 DUF5600 288 394 Domain of unknown function (DUF5600) Domain
PF12763 EF-hand_4 439 535 Cytoskeletal-regulatory complex EF hand Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta. {ECO:0000269|PubMed:10673336}.
Sequence
Sequence length 535
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Endocytosis   Factors involved in megakaryocyte development and platelet production
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