SOCS7 (suppressor of cytokine signaling 7)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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30837 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Suppressor of cytokine signaling 7 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SOCS7 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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NAP4, NCKAP4 |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q12 |
miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | O14512 | |||||||||||||||
Protein name | Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4) | |||||||||||||||
Protein function | Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1 (Pu | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in brain and leukocytes (PubMed:9344857). Also in fetal lung fibroblasts and fetal brain (PubMed:9344857). {ECO:0000269|PubMed:9344857}. | |||||||||||||||
Sequence |
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Sequence length | 581 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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