H2AC8 (H2A clustered histone 8)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Pathways
Entrez ID 3012
Gene name H2A clustered histone 8
Gene symbol H2AC8
Synonyms (NCBI Gene)
H2A.1H2A.2H2A/aH2AC4H2AFAHIST1H2AE
Chromosome 6
Chromosome location 6p22.2
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core hi
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
Gene Gene ontology Other IDs Pathways
Show/Hide all (20)
GO ID Ontology Definition Evidence Reference
GO:0000786 Component Nucleosome IBA
GO:0000786 Component Nucleosome IEA
GO:0000786 Component Nucleosome IPI 20498094, 21812398, 26694698
GO:0003677 Function DNA binding IEA
GO:0003677 Function DNA binding NAS 6647026
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Pathways
MIM HGNC e!Ensembl
602786 4724 ENSG00000277075
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Pathways
  KEGG  Reactome
  ATP-dependent chromatin remodeling
Necroptosis
Neutrophil extracellular trap formation
Alcoholism
Systemic lupus erythematosus 		  Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
RMTs methylate histone arginines
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
UCH proteinases
Ub-specific processing proteases
Metalloprotease DUBs
Deposition of new CENPA-containing nucleosomes at the centromere
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression
HCMV Early Events
HCMV Late Events
Amyloid fiber formation