NXPH1 (neurexophilin 1)

Gene

• Entrez ID: 30010
• Gene name: Neurexophilin 1
• Gene symbol: NXPH1
• Synonyms (NCBI Gene): NPH1, Nbla00697
• Chromosome: 7
• Chromosome location: 7p21.3
• Summary: This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1200546	hsa-let-7a	CLIP-seq
MIRT1200547	hsa-let-7b	CLIP-seq
MIRT1200548	hsa-let-7c	CLIP-seq
MIRT1200549	hsa-let-7d	CLIP-seq
MIRT1200550	hsa-let-7e	CLIP-seq
MIRT1200551	hsa-let-7f	CLIP-seq
MIRT1200552	hsa-let-7g	CLIP-seq
MIRT1200553	hsa-let-7i	CLIP-seq
MIRT1200554	hsa-miR-1285	CLIP-seq
MIRT1200555	hsa-miR-1287	CLIP-seq
MIRT1200556	hsa-miR-1304	CLIP-seq
MIRT1200557	hsa-miR-1305	CLIP-seq
MIRT1200558	hsa-miR-146b-3p	CLIP-seq
MIRT1200559	hsa-miR-194	CLIP-seq
MIRT1200560	hsa-miR-202	CLIP-seq
MIRT1200561	hsa-miR-3065-5p	CLIP-seq
MIRT1200562	hsa-miR-3135b	CLIP-seq
MIRT1200563	hsa-miR-3148	CLIP-seq
MIRT1200564	hsa-miR-3187-5p	CLIP-seq
MIRT1200565	hsa-miR-3194-3p	CLIP-seq
MIRT1200566	hsa-miR-323-3p	CLIP-seq
MIRT1200567	hsa-miR-339-5p	CLIP-seq
MIRT1200568	hsa-miR-3613-5p	CLIP-seq
MIRT1200569	hsa-miR-3924	CLIP-seq
MIRT1200570	hsa-miR-409-3p	CLIP-seq
MIRT1200571	hsa-miR-421	CLIP-seq
MIRT1200572	hsa-miR-4427	CLIP-seq
MIRT1200573	hsa-miR-4458	CLIP-seq
MIRT1200574	hsa-miR-4500	CLIP-seq
MIRT1200575	hsa-miR-4659a-3p	CLIP-seq
MIRT1200576	hsa-miR-4659b-3p	CLIP-seq
MIRT1200577	hsa-miR-4680-3p	CLIP-seq
MIRT1200578	hsa-miR-4728-3p	CLIP-seq
MIRT1200579	hsa-miR-4778-3p	CLIP-seq
MIRT1200580	hsa-miR-499-3p	CLIP-seq
MIRT1200581	hsa-miR-499a-3p	CLIP-seq
MIRT1200582	hsa-miR-568	CLIP-seq
MIRT1200583	hsa-miR-612	CLIP-seq
MIRT1200584	hsa-miR-759	CLIP-seq
MIRT1200585	hsa-miR-875-3p	CLIP-seq
MIRT1200586	hsa-miR-98	CLIP-seq
MIRT1200554	hsa-miR-1285	CLIP-seq
MIRT1200564	hsa-miR-3187-5p	CLIP-seq
MIRT1200580	hsa-miR-499-3p	CLIP-seq
MIRT1200581	hsa-miR-499a-3p	CLIP-seq
MIRT1200583	hsa-miR-612	CLIP-seq
MIRT1200554	hsa-miR-1285	CLIP-seq
MIRT1200564	hsa-miR-3187-5p	CLIP-seq
MIRT1200580	hsa-miR-499-3p	CLIP-seq
MIRT1200581	hsa-miR-499a-3p	CLIP-seq
MIRT1200583	hsa-miR-612	CLIP-seq
MIRT1200554	hsa-miR-1285	CLIP-seq
MIRT1200564	hsa-miR-3187-5p	CLIP-seq
MIRT1200580	hsa-miR-499-3p	CLIP-seq
MIRT1200581	hsa-miR-499a-3p	CLIP-seq
MIRT2058022	hsa-miR-587	CLIP-seq
MIRT1200583	hsa-miR-612	CLIP-seq
MIRT1200584	hsa-miR-759	CLIP-seq
MIRT1200546	hsa-let-7a	CLIP-seq
MIRT1200547	hsa-let-7b	CLIP-seq
MIRT1200548	hsa-let-7c	CLIP-seq
MIRT1200549	hsa-let-7d	CLIP-seq
MIRT1200550	hsa-let-7e	CLIP-seq
MIRT1200551	hsa-let-7f	CLIP-seq
MIRT1200552	hsa-let-7g	CLIP-seq
MIRT1200553	hsa-let-7i	CLIP-seq
MIRT2286411	hsa-miR-1248	CLIP-seq
MIRT1200554	hsa-miR-1285	CLIP-seq
MIRT1200556	hsa-miR-1304	CLIP-seq
MIRT1200559	hsa-miR-194	CLIP-seq
MIRT1200560	hsa-miR-202	CLIP-seq
MIRT1200564	hsa-miR-3187-5p	CLIP-seq
MIRT1200573	hsa-miR-4458	CLIP-seq
MIRT1200574	hsa-miR-4500	CLIP-seq
MIRT1200575	hsa-miR-4659a-3p	CLIP-seq
MIRT1200576	hsa-miR-4659b-3p	CLIP-seq
MIRT1200579	hsa-miR-4778-3p	CLIP-seq
MIRT1200580	hsa-miR-499-3p	CLIP-seq
MIRT1200581	hsa-miR-499a-3p	CLIP-seq
MIRT2058022	hsa-miR-587	CLIP-seq
MIRT1200583	hsa-miR-612	CLIP-seq
MIRT2286412	hsa-miR-642b	CLIP-seq
MIRT1200586	hsa-miR-98	CLIP-seq
MIRT1200554	hsa-miR-1285	CLIP-seq
MIRT1200564	hsa-miR-3187-5p	CLIP-seq
MIRT1200580	hsa-miR-499-3p	CLIP-seq
MIRT1200581	hsa-miR-499a-3p	CLIP-seq
MIRT1200583	hsa-miR-612	CLIP-seq
MIRT2584401	hsa-miR-338-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005102	Function	Signaling receptor binding	IBA
GO:0005102	Function	Signaling receptor binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0043083	Component	Synaptic cleft	IEA
GO:0050804	Process	Modulation of chemical synaptic transmission	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0098982	Component	GABA-ergic synapse	IEA

Other IDs

• MIM: 604639
• HGNC: 20693
• e!Ensembl: ENSG00000122584

Protein

• UniProt ID: P58417
• Protein name: Neurexophilin-1
• Protein function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06312	Neurexophilin	63 → 271	Neurexophilin	Family

• Sequence:

  MQAACWYVLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLS
  QTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFG
  WGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQ
  QTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICI
  YISFYSTDYKLVQKVCPDYNYHSDTPYFPSG

• Sequence length: 271