NRBF2 (nuclear receptor binding factor 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 29982 |
| Gene name | Nuclear receptor binding factor 2 |
| Gene symbol | NRBF2 |
| Synonyms (NCBI Gene) |
COPRCOPR1COPR2NRBF-2
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| Chromosome | 10 |
| Chromosome location | 10q21.3 |
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miRNA
miRNA information provided by mirtarbase database.
693
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
13
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96F24 | |||||||||||||||
| Protein name | Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR) | |||||||||||||||
| Protein function | May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). ; Involved in starvation-induced autophagy probably by its association with PI3K comple | |||||||||||||||
| PDB | 4ZEY | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852). {ECO:0000269|PubMed:15610520, ECO:0000269|PubMed:18619852}. | |||||||||||||||
| Sequence |
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| Sequence length | 287 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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