A1CF (APOBEC1 complementation factor)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 29974 |
| Gene name | APOBEC1 complementation factor |
| Gene symbol | A1CF |
| Synonyms (NCBI Gene) |
ACFACF64ACF65APOBEC1CFASP
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| Chromosome | 10 |
| Chromosome location | 10q11.23 |
| Summary | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NQ94 | |||||||||||||||||||||||||
| Protein name | APOBEC1 complementation factor (APOBEC1-stimulating protein) | |||||||||||||||||||||||||
| Protein function | Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docki | |||||||||||||||||||||||||
| PDB | 2CPD | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed with highest levels in brain, liver, pancreas, colon and spleen. {ECO:0000269|PubMed:10669759}. | |||||||||||||||||||||||||
| Sequence |
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| Sequence length | 594 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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